arXiv subjects

Luping Zhou

Publications and source records attributed to Luping Zhou.

At least 73 records · Page 4Linked to original sources

arXiv2023

Rethinking Data Perturbation and Model Stabilization for Semi-supervised Medical Image Segmentation

Studies on semi-supervised medical image segmentation (SSMIS) have seen fast progress recently. Due to the limited labelled data, SSMIS methods mainly focus on effectively leveraging unlabeled data to enhance the segmentation performance. However, despite their promising performance, current state-of-the-art methods often prioritize integrating complex techniques and loss terms rather than addressing the core challenges of semi-supervised scenarios directly. We argue that the key to SSMIS lies in generating substantial and appropriate prediction disagreement on unlabeled data. To this end, we emphasize the crutiality of data perturbation and model stabilization in semi-supervised segmentation, and propose a simple yet effective approach to boost SSMIS performance significantly, dubbed DPMS. Specifically, we first revisit SSMIS from three distinct perspectives: the data, the model, and the loss, and conduct a comprehensive study of corresponding strategies to examine their effectiveness. Based on these examinations, we then propose DPMS, which adopts a plain teacher-student framework with a standard supervised loss and unsupervised consistency loss. To produce appropriate prediction disagreements, DPMS perturbs the unlabeled data via strong augmentations to enlarge prediction disagreements considerably. On the other hand, using EMA teacher when strong augmentation is applied does not necessarily improve performance. DPMS further utilizes a forwarding-twice and momentum updating strategies for normalization statistics to stabilize the training on unlabeled data effectively. Despite its simplicity, DPMS can obtain new state-of-the-art performance on the public 2D ACDC and 3D LA datasets across various semi-supervised settings, e.g. obtaining a remarkable 22.62% improvement against previous SOTA on ACDC with 5% labels.

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arXiv2023

Contrastive Diffusion Model with Auxiliary Guidance for Coarse-to-Fine PET Reconstruction

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One widely adopted technique is the generative adversarial networks (GANs), yet recently, diffusion probabilistic models (DPMs) have emerged as a compelling alternative due to their improved sample quality and higher log-likelihood scores compared to GANs. Despite this, DPMs suffer from two major drawbacks in real clinical settings, i.e., the computationally expensive sampling process and the insufficient preservation of correspondence between the conditioning LPET image and the reconstructed PET (RPET) image. To address the above limitations, this paper presents a coarse-to-fine PET reconstruction framework that consists of a coarse prediction module (CPM) and an iterative refinement module (IRM). The CPM generates a coarse PET image via a deterministic process, and the IRM samples the residual iteratively. By delegating most of the computational overhead to the CPM, the overall sampling speed of our method can be significantly improved. Furthermore, two additional strategies, i.e., an auxiliary guidance strategy and a contrastive diffusion strategy, are proposed and integrated into the reconstruction process, which can enhance the correspondence between the LPET image and the RPET image, further improving clinical reliability. Extensive experiments on two human brain PET datasets demonstrate that our method outperforms the state-of-the-art PET reconstruction methods. The source code is available at \url{https://github.com/Show-han/PET-Reconstruction}.

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arXiv2023

Towards Semi-supervised Learning with Non-random Missing Labels

Semi-supervised learning (SSL) tackles the label missing problem by enabling the effective usage of unlabeled data. While existing SSL methods focus on the traditional setting, a practical and challenging scenario called label Missing Not At Random (MNAR) is usually ignored. In MNAR, the labeled and unlabeled data fall into different class distributions resulting in biased label imputation, which deteriorates the performance of SSL models. In this work, class transition tracking based Pseudo-Rectifying Guidance (PRG) is devised for MNAR. We explore the class-level guidance information obtained by the Markov random walk, which is modeled on a dynamically created graph built over the class tracking matrix. PRG unifies the historical information of class distribution and class transitions caused by the pseudo-rectifying procedure to maintain the model's unbiased enthusiasm towards assigning pseudo-labels to all classes, so as the quality of pseudo-labels on both popular classes and rare classes in MNAR could be improved. Finally, we show the superior performance of PRG across a variety of MNAR scenarios, outperforming the latest SSL approaches combining bias removal solutions by a large margin. Code and model weights are available at https://github.com/NJUyued/PRG4SSL-MNAR.

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arXiv2023

Automatic Radiology Report Generation by Learning with Increasingly Hard Negatives

Automatic radiology report generation is challenging as medical images or reports are usually similar to each other due to the common content of anatomy. This makes a model hard to capture the uniqueness of individual images and is prone to producing undesired generic or mismatched reports. This situation calls for learning more discriminative features that could capture even fine-grained mismatches between images and reports. To achieve this, this paper proposes a novel framework to learn discriminative image and report features by distinguishing them from their closest peers, i.e., hard negatives. Especially, to attain more discriminative features, we gradually raise the difficulty of such a learning task by creating increasingly hard negative reports for each image in the feature space during training, respectively. By treating the increasingly hard negatives as auxiliary variables, we formulate this process as a min-max alternating optimisation problem. At each iteration, conditioned on a given set of hard negative reports, image and report features are learned as usual by minimising the loss functions related to report generation. After that, a new set of harder negative reports will be created by maximising a loss reflecting image-report alignment. By solving this optimisation, we attain a model that can generate more specific and accurate reports. It is noteworthy that our framework enhances discriminative feature learning without introducing extra network weights. Also, in contrast to the existing way of generating hard negatives, our framework extends beyond the granularity of the dataset by generating harder samples out of the training set. Experimental study on benchmark datasets verifies the efficacy of our framework and shows that it can serve as a plug-in to readily improve existing medical report generation models.

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arXiv2023

Q2ATransformer: Improving Medical VQA via an Answer Querying Decoder

Medical Visual Question Answering (VQA) systems play a supporting role to understand clinic-relevant information carried by medical images. The questions to a medical image include two categories: close-end (such as Yes/No question) and open-end. To obtain answers, the majority of the existing medical VQA methods relies on classification approaches, while a few works attempt to use generation approaches or a mixture of the two. The classification approaches are relatively simple but perform poorly on long open-end questions. To bridge this gap, in this paper, we propose a new Transformer based framework for medical VQA (named as Q2ATransformer), which integrates the advantages of both the classification and the generation approaches and provides a unified treatment for the close-end and open-end questions. Specifically, we introduce an additional Transformer decoder with a set of learnable candidate answer embeddings to query the existence of each answer class to a given image-question pair. Through the Transformer attention, the candidate answer embeddings interact with the fused features of the image-question pair to make the decision. In this way, despite being a classification-based approach, our method provides a mechanism to interact with the answer information for prediction like the generation-based approaches. On the other hand, by classification, we mitigate the task difficulty by reducing the search space of answers. Our method achieves new state-of-the-art performance on two medical VQA benchmarks. Especially, for the open-end questions, we achieve 79.19% on VQA-RAD and 54.85% on PathVQA, with 16.09% and 41.45% absolute improvements, respectively.

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arXiv2023

Neural Vector Fields: Implicit Representation by Explicit Learning

Deep neural networks (DNNs) are widely applied for nowadays 3D surface reconstruction tasks and such methods can be further divided into two categories, which respectively warp templates explicitly by moving vertices or represent 3D surfaces implicitly as signed or unsigned distance functions. Taking advantage of both advanced explicit learning process and powerful representation ability of implicit functions, we propose a novel 3D representation method, Neural Vector Fields (NVF). It not only adopts the explicit learning process to manipulate meshes directly, but also leverages the implicit representation of unsigned distance functions (UDFs) to break the barriers in resolution and topology. Specifically, our method first predicts the displacements from queries towards the surface and models the shapes as \textit{Vector Fields}. Rather than relying on network differentiation to obtain direction fields as most existing UDF-based methods, the produced vector fields encode the distance and direction fields both and mitigate the ambiguity at "ridge" points, such that the calculation of direction fields is straightforward and differentiation-free. The differentiation-free characteristic enables us to further learn a shape codebook via Vector Quantization, which encodes the cross-object priors, accelerates the training procedure, and boosts model generalization on cross-category reconstruction. The extensive experiments on surface reconstruction benchmarks indicate that our method outperforms those state-of-the-art methods in different evaluation scenarios including watertight vs non-watertight shapes, category-specific vs category-agnostic reconstruction, category-unseen reconstruction, and cross-domain reconstruction. Our code is released at https://github.com/Wi-sc/NVF.

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arXiv2023

Single-view 3D Mesh Reconstruction for Seen and Unseen Categories

Single-view 3D object reconstruction is a fundamental and challenging computer vision task that aims at recovering 3D shapes from single-view RGB images. Most existing deep learning based reconstruction methods are trained and evaluated on the same categories, and they cannot work well when handling objects from novel categories that are not seen during training. Focusing on this issue, this paper tackles Single-view 3D Mesh Reconstruction, to study the model generalization on unseen categories and encourage models to reconstruct objects literally. Specifically, we propose an end-to-end two-stage network, GenMesh, to break the category boundaries in reconstruction. Firstly, we factorize the complicated image-to-mesh mapping into two simpler mappings, i.e., image-to-point mapping and point-to-mesh mapping, while the latter is mainly a geometric problem and less dependent on object categories. Secondly, we devise a local feature sampling strategy in 2D and 3D feature spaces to capture the local geometry shared across objects to enhance model generalization. Thirdly, apart from the traditional point-to-point supervision, we introduce a multi-view silhouette loss to supervise the surface generation process, which provides additional regularization and further relieves the overfitting problem. The experimental results show that our method significantly outperforms the existing works on the ShapeNet and Pix3D under different scenarios and various metrics, especially for novel objects. The project link is https://github.com/Wi-sc/GenMesh.

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arXiv2023

Learning Partial Correlation based Deep Visual Representation for Image Classification

Visual representation based on covariance matrix has demonstrates its efficacy for image classification by characterising the pairwise correlation of different channels in convolutional feature maps. However, pairwise correlation will become misleading once there is another channel correlating with both channels of interest, resulting in the ``confounding'' effect. For this case, ``partial correlation'' which removes the confounding effect shall be estimated instead. Nevertheless, reliably estimating partial correlation requires to solve a symmetric positive definite matrix optimisation, known as sparse inverse covariance estimation (SICE). How to incorporate this process into CNN remains an open issue. In this work, we formulate SICE as a novel structured layer of CNN. To ensure end-to-end trainability, we develop an iterative method to solve the above matrix optimisation during forward and backward propagation steps. Our work obtains a partial correlation based deep visual representation and mitigates the small sample problem often encountered by covariance matrix estimation in CNN. Computationally, our model can be effectively trained with GPU and works well with a large number of channels of advanced CNNs. Experiments show the efficacy and superior classification performance of our deep visual representation compared to covariance matrix based counterparts.

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arXiv2023

METransformer: Radiology Report Generation by Transformer with Multiple Learnable Expert Tokens

In clinical scenarios, multi-specialist consultation could significantly benefit the diagnosis, especially for intricate cases. This inspires us to explore a "multi-expert joint diagnosis" mechanism to upgrade the existing "single expert" framework commonly seen in the current literature. To this end, we propose METransformer, a method to realize this idea with a transformer-based backbone. The key design of our method is the introduction of multiple learnable "expert" tokens into both the transformer encoder and decoder. In the encoder, each expert token interacts with both vision tokens and other expert tokens to learn to attend different image regions for image representation. These expert tokens are encouraged to capture complementary information by an orthogonal loss that minimizes their overlap. In the decoder, each attended expert token guides the cross-attention between input words and visual tokens, thus influencing the generated report. A metrics-based expert voting strategy is further developed to generate the final report. By the multi-experts concept, our model enjoys the merits of an ensemble-based approach but through a manner that is computationally more efficient and supports more sophisticated interactions among experts. Experimental results demonstrate the promising performance of our proposed model on two widely used benchmarks. Last but not least, the framework-level innovation makes our work ready to incorporate advances on existing "single-expert" models to further improve its performance.

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arXiv2023

Task-Oriented Multi-Modal Mutual Leaning for Vision-Language Models

Prompt learning has become one of the most efficient paradigms for adapting large pre-trained vision-language models to downstream tasks. Current state-of-the-art methods, like CoOp and ProDA, tend to adopt soft prompts to learn an appropriate prompt for each specific task. Recent CoCoOp further boosts the base-to-new generalization performance via an image-conditional prompt. However, it directly fuses identical image semantics to prompts of different labels and significantly weakens the discrimination among different classes as shown in our experiments. Motivated by this observation, we first propose a class-aware text prompt (CTP) to enrich generated prompts with label-related image information. Unlike CoCoOp, CTP can effectively involve image semantics and avoid introducing extra ambiguities into different prompts. On the other hand, instead of reserving the complete image representations, we propose text-guided feature tuning (TFT) to make the image branch attend to class-related representation. A contrastive loss is employed to align such augmented text and image representations on downstream tasks. In this way, the image-to-text CTP and text-to-image TFT can be mutually promoted to enhance the adaptation of VLMs for downstream tasks. Extensive experiments demonstrate that our method outperforms the existing methods by a significant margin. Especially, compared to CoCoOp, we achieve an average improvement of 4.03% on new classes and 3.19% on harmonic-mean over eleven classification benchmarks.

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arXiv2023

Conflict-Based Cross-View Consistency for Semi-Supervised Semantic Segmentation

Semi-supervised semantic segmentation (SSS) has recently gained increasing research interest as it can reduce the requirement for large-scale fully-annotated training data. The current methods often suffer from the confirmation bias from the pseudo-labelling process, which can be alleviated by the co-training framework. The current co-training-based SSS methods rely on hand-crafted perturbations to prevent the different sub-nets from collapsing into each other, but these artificial perturbations cannot lead to the optimal solution. In this work, we propose a new conflict-based cross-view consistency (CCVC) method based on a two-branch co-training framework which aims at enforcing the two sub-nets to learn informative features from irrelevant views. In particular, we first propose a new cross-view consistency (CVC) strategy that encourages the two sub-nets to learn distinct features from the same input by introducing a feature discrepancy loss, while these distinct features are expected to generate consistent prediction scores of the input. The CVC strategy helps to prevent the two sub-nets from stepping into the collapse. In addition, we further propose a conflict-based pseudo-labelling (CPL) method to guarantee the model will learn more useful information from conflicting predictions, which will lead to a stable training process. We validate our new CCVC approach on the SSS benchmark datasets where our method achieves new state-of-the-art performance. Our code is available at https://github.com/xiaoyao3302/CCVC.

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arXiv2023

Bridging Synthetic and Real Images: a Transferable and Multiple Consistency aided Fundus Image Enhancement Framework

Deep learning based image enhancement models have largely improved the readability of fundus images in order to decrease the uncertainty of clinical observations and the risk of misdiagnosis. However, due to the difficulty of acquiring paired real fundus images at different qualities, most existing methods have to adopt synthetic image pairs as training data. The domain shift between the synthetic and the real images inevitably hinders the generalization of such models on clinical data. In this work, we propose an end-to-end optimized teacher-student framework to simultaneously conduct image enhancement and domain adaptation. The student network uses synthetic pairs for supervised enhancement, and regularizes the enhancement model to reduce domain-shift by enforcing teacher-student prediction consistency on the real fundus images without relying on enhanced ground-truth. Moreover, we also propose a novel multi-stage multi-attention guided enhancement network (MAGE-Net) as the backbones of our teacher and student network. Our MAGE-Net utilizes multi-stage enhancement module and retinal structure preservation module to progressively integrate the multi-scale features and simultaneously preserve the retinal structures for better fundus image quality enhancement. Comprehensive experiments on both real and synthetic datasets demonstrate that our framework outperforms the baseline approaches. Moreover, our method also benefits the downstream clinical tasks.

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arXiv2022

MutexMatch: Semi-Supervised Learning with Mutex-Based Consistency Regularization

The core issue in semi-supervised learning (SSL) lies in how to effectively leverage unlabeled data, whereas most existing methods tend to put a great emphasis on the utilization of high-confidence samples yet seldom fully explore the usage of low-confidence samples. In this paper, we aim to utilize low-confidence samples in a novel way with our proposed mutex-based consistency regularization, namely MutexMatch. Specifically, the high-confidence samples are required to exactly predict "what it is" by conventional True-Positive Classifier, while the low-confidence samples are employed to achieve a simpler goal -- to predict with ease "what it is not" by True-Negative Classifier. In this sense, we not only mitigate the pseudo-labeling errors but also make full use of the low-confidence unlabeled data by consistency of dissimilarity degree. MutexMatch achieves superior performance on multiple benchmark datasets, i.e., CIFAR-10, CIFAR-100, SVHN, STL-10, mini-ImageNet and Tiny-ImageNet. More importantly, our method further shows superiority when the amount of labeled data is scarce, e.g., 92.23% accuracy with only 20 labeled data on CIFAR-10. Our code and model weights have been released at https://github.com/NJUyued/MutexMatch4SSL.

cs.CV↗

arXiv2022

Augmentation Matters: A Simple-yet-Effective Approach to Semi-supervised Semantic Segmentation

Recent studies on semi-supervised semantic segmentation (SSS) have seen fast progress. Despite their promising performance, current state-of-the-art methods tend to increasingly complex designs at the cost of introducing more network components and additional training procedures. Differently, in this work, we follow a standard teacher-student framework and propose AugSeg, a simple and clean approach that focuses mainly on data perturbations to boost the SSS performance. We argue that various data augmentations should be adjusted to better adapt to the semi-supervised scenarios instead of directly applying these techniques from supervised learning. Specifically, we adopt a simplified intensity-based augmentation that selects a random number of data transformations with uniformly sampling distortion strengths from a continuous space. Based on the estimated confidence of the model on different unlabeled samples, we also randomly inject labelled information to augment the unlabeled samples in an adaptive manner. Without bells and whistles, our simple AugSeg can readily achieve new state-of-the-art performance on SSS benchmarks under different partition protocols.

cs.CV↗

arXiv2022

Instance-specific and Model-adaptive Supervision for Semi-supervised Semantic Segmentation

Recently, semi-supervised semantic segmentation has achieved promising performance with a small fraction of labeled data. However, most existing studies treat all unlabeled data equally and barely consider the differences and training difficulties among unlabeled instances. Differentiating unlabeled instances can promote instance-specific supervision to adapt to the model's evolution dynamically. In this paper, we emphasize the cruciality of instance differences and propose an instance-specific and model-adaptive supervision for semi-supervised semantic segmentation, named iMAS. Relying on the model's performance, iMAS employs a class-weighted symmetric intersection-over-union to evaluate quantitative hardness of each unlabeled instance and supervises the training on unlabeled data in a model-adaptive manner. Specifically, iMAS learns from unlabeled instances progressively by weighing their corresponding consistency losses based on the evaluated hardness. Besides, iMAS dynamically adjusts the augmentation for each instance such that the distortion degree of augmented instances is adapted to the model's generalization capability across the training course. Not integrating additional losses and training procedures, iMAS can obtain remarkable performance gains against current state-of-the-art approaches on segmentation benchmarks under different semi-supervised partition protocols.

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arXiv2022

A Medical Semantic-Assisted Transformer for Radiographic Report Generation

Automated radiographic report generation is a challenging cross-domain task that aims to automatically generate accurate and semantic-coherence reports to describe medical images. Despite the recent progress in this field, there are still many challenges at least in the following aspects. First, radiographic images are very similar to each other, and thus it is difficult to capture the fine-grained visual differences using CNN as the visual feature extractor like many existing methods. Further, semantic information has been widely applied to boost the performance of generation tasks (e.g. image captioning), but existing methods often fail to provide effective medical semantic features. Toward solving those problems, in this paper, we propose a memory-augmented sparse attention block utilizing bilinear pooling to capture the higher-order interactions between the input fine-grained image features while producing sparse attention. Moreover, we introduce a novel Medical Concepts Generation Network (MCGN) to predict fine-grained semantic concepts and incorporate them into the report generation process as guidance. Our proposed method shows promising performance on the recently released largest benchmark MIMIC-CXR. It outperforms multiple state-of-the-art methods in image captioning and medical report generation.

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arXiv2022

Instance Image Retrieval by Learning Purely From Within the Dataset

Quality feature representation is key to instance image retrieval. To attain it, existing methods usually resort to a deep model pre-trained on benchmark datasets or even fine-tune the model with a task-dependent labelled auxiliary dataset. Although achieving promising results, this approach is restricted by two issues: 1) the domain gap between benchmark datasets and the dataset of a given retrieval task; 2) the required auxiliary dataset cannot be readily obtained. In light of this situation, this work looks into a different approach which has not been well investigated for instance image retrieval previously: {can we learn feature representation \textit{specific to} a given retrieval task in order to achieve excellent retrieval?} Our finding is encouraging. By adding an object proposal generator to generate image regions for self-supervised learning, the investigated approach can successfully learn feature representation specific to a given dataset for retrieval. This representation can be made even more effective by boosting it with image similarity information mined from the dataset. As experimentally validated, such a simple ``self-supervised learning + self-boosting'' approach can well compete with the relevant state-of-the-art retrieval methods. Ablation study is conducted to show the appealing properties of this approach and its limitation on generalisation across datasets.

cs.CV↗

arXiv2022

RDA: Reciprocal Distribution Alignment for Robust Semi-supervised Learning

In this work, we propose Reciprocal Distribution Alignment (RDA) to address semi-supervised learning (SSL), which is a hyperparameter-free framework that is independent of confidence threshold and works with both the matched (conventionally) and the mismatched class distributions. Distribution mismatch is an often overlooked but more general SSL scenario where the labeled and the unlabeled data do not fall into the identical class distribution. This may lead to the model not exploiting the labeled data reliably and drastically degrade the performance of SSL methods, which could not be rescued by the traditional distribution alignment. In RDA, we enforce a reciprocal alignment on the distributions of the predictions from two classifiers predicting pseudo-labels and complementary labels on the unlabeled data. These two distributions, carrying complementary information, could be utilized to regularize each other without any prior of class distribution. Moreover, we theoretically show that RDA maximizes the input-output mutual information. Our approach achieves promising performance in SSL under a variety of scenarios of mismatched distributions, as well as the conventional matched SSL setting. Our code is available at: https://github.com/NJUyued/RDA4RobustSSL.

cs.LG↗