arXiv subjects

Martin Renqiang Min

Publications and source records attributed to Martin Renqiang Min.

At least 19 recordsLinked to original sources

arXiv2026

DiscussLLM: Teaching Large Language Models When to Speak

Large Language Models (LLMs) have demonstrated remarkable capabilities in understanding and generating human-like text, yet they largely operate as reactive agents, responding only when directly prompted. This passivity creates an "awareness gap," limiting their potential as truly collaborative partners in dynamic human discussions. We introduce $\textit{DiscussLLM}$, a framework designed to bridge this gap by training models to proactively decide not just $\textit{what}$ to say, but critically, $\textit{when}$ to speak. Our primary contribution is a scalable two-stage data generation pipeline that synthesizes a large-scale dataset of realistic multi-turn human discussions. Each discussion is annotated with one of five intervention types (e.g., Factual Correction, Concept Definition) and contains an explicit conversational trigger where an AI intervention adds value. By training models to predict a special silent token when no intervention is needed, they learn to remain quiet until a helpful contribution can be made. We explore two architectural baselines: an integrated end-to-end model and a decoupled classifier-generator system optimized for low-latency inference. We evaluate these models on their ability to accurately time interventions and generate helpful responses, paving the way for more situationally aware and proactive conversational AI.

cs.CL↗

arXiv2026

CalibFree: Self-Supervised View Feature Separation for Calibration-Free Multi-Camera Multi-Object Tracking

Multi-camera multi-object tracking (MCMOT) faces significant challenges in maintaining consistent object identities across varying camera perspectives, particularly when precise calibration and extensive annotations are required. In this paper, we present CalibFree, a self-supervised representation learning framework that does not need any calibration or manual labeling for the MCMOT task. By promoting feature separation between view-agnostic and view-specific representations through single-view distillation and cross-view reconstruction, our method adapts to complex, dynamic scenarios with minimal overhead. Experiments on the MMP-MvMHAT dataset show a 3% improvement in overall accuracy and a 7.5% increase in the average F1 score over state-of-the-art approaches, confirming the effectiveness of our calibration-free design. Moreover, on the more diverse MvMHAT dataset, our approach demonstrates superior over-time tracking and strong cross-view performance, highlighting its adaptability to a wide range of camera configurations. Code will be publicly available upon acceptance.

cs.CV↗

arXiv2026

Uncertainty-Guided Latent Diagnostic Trajectory Learning for Sequential Clinical Diagnosis

Clinical diagnosis requires sequential evidence acquisition under uncertainty. However, most Large Language Model (LLM) based diagnostic systems assume fully observed patient information and therefore do not explicitly model how clinical evidence should be sequentially acquired over time. Even when diagnosis is formulated as a sequential decision process, it is still challenging to learn effective diagnostic trajectories. This is because the space of possible evidence-acquisition paths is relatively large, while clinical datasets rarely provide explicit supervision information for desirable diagnostic paths. To this end, we formulate sequential diagnosis as a Latent Diagnostic Trajectory Learning (LDTL) framework based on a planning LLM agent and a diagnostic LLM agent. For the diagnostic LLM agent, diagnostic action sequences are treated as latent paths and we introduce a posterior distribution that prioritizes trajectories providing more diagnostic information. The planning LLM agent is then trained to follow this distribution, encouraging coherent diagnostic trajectories that progressively reduce uncertainty. Experiments on the MIMIC-CDM benchmark demonstrate that our proposed LDTL framework outperforms existing baselines in diagnostic accuracy under a sequential clinical diagnosis setting, while requiring fewer diagnostic tests. Furthermore, ablation studies highlight the critical role of trajectory-level posterior alignment in achieving these improvements.

cs.AI↗

arXiv2025

DICE: Discrete Inversion Enabling Controllable Editing for Multinomial Diffusion and Masked Generative Models

Discrete diffusion models have achieved success in tasks like image generation and masked language modeling but face limitations in controlled content editing. We introduce DICE (Discrete Inversion for Controllable Editing), the first approach to enable precise inversion for discrete diffusion models, including multinomial diffusion and masked generative models. By recording noise sequences and masking patterns during the reverse diffusion process, DICE enables accurate reconstruction and flexible editing of discrete data without the need for predefined masks or attention manipulation. We demonstrate the effectiveness of DICE across both image and text domains, evaluating it on models such as VQ-Diffusion, Paella, and RoBERTa. Our results show that DICE preserves high data fidelity while enhancing editing capabilities, offering new opportunities for fine-grained content manipulation in discrete spaces.

cs.CV↗

arXiv2025

EditGRPO: Reinforcement Learning with Post-Rollout Edits for Clinically Accurate Chest X-Ray Report Generation

Radiology report generation requires advanced medical image analysis, effective temporal reasoning, and accurate text generation. Although recent innovations, particularly multimodal large language models, have shown improved performance, their supervised fine-tuning (SFT) objective is not explicitly aligned with clinical efficacy. In this work, we introduce EditGRPO, a mixed-policy reinforcement learning algorithm designed specifically to optimize the generation through clinically motivated rewards. EditGRPO integrates on-policy exploration with off-policy guidance by injecting sentence-level detailed corrections during training rollouts. This mixed-policy approach addresses the exploration dilemma and sampling efficiency issues typically encountered in RL. Applied to a Qwen2.5-VL-3B, EditGRPO outperforms both SFT and vanilla GRPO baselines, achieving an average improvement of 3.4\% in clinical metrics across four major datasets. Notably, EditGRPO also demonstrates superior out-of-domain generalization, with an average performance gain of 5.9\% on unseen datasets.

cs.CL↗

arXiv2025

PPDiff: Diffusing in Hybrid Sequence-Structure Space for Protein-Protein Complex Design

Designing protein-binding proteins with high affinity is critical in biomedical research and biotechnology. Despite recent advancements targeting specific proteins, the ability to create high-affinity binders for arbitrary protein targets on demand, without extensive rounds of wet-lab testing, remains a significant challenge. Here, we introduce PPDiff, a diffusion model to jointly design the sequence and structure of binders for arbitrary protein targets in a non-autoregressive manner. PPDiffbuilds upon our developed Sequence Structure Interleaving Network with Causal attention layers (SSINC), which integrates interleaved self-attention layers to capture global amino acid correlations, k-nearest neighbor (kNN) equivariant graph layers to model local interactions in three-dimensional (3D) space, and causal attention layers to simplify the intricate interdependencies within the protein sequence. To assess PPDiff, we curate PPBench, a general protein-protein complex dataset comprising 706,360 complexes from the Protein Data Bank (PDB). The model is pretrained on PPBenchand finetuned on two real-world applications: target-protein mini-binder complex design and antigen-antibody complex design. PPDiffconsistently surpasses baseline methods, achieving success rates of 50.00%, 23.16%, and 16.89% for the pretraining task and the two downstream applications, respectively. The code, data and models are available at https://github.com/JocelynSong/PPDiff.

cs.LG↗

arXiv2025

Object-Aware 4D Human Motion Generation

Recent advances in video diffusion models have enabled the generation of high-quality videos. However, these videos still suffer from unrealistic deformations, semantic violations, and physical inconsistencies that are largely rooted in the absence of 3D physical priors. To address these challenges, we propose an object-aware 4D human motion generation framework grounded in 3D Gaussian representations and motion diffusion priors. With pre-generated 3D humans and objects, our method, Motion Score Distilled Interaction (MSDI), employs the spatial and prompt semantic information in large language models (LLMs) and motion priors through the proposed Motion Diffusion Score Distillation Sampling (MSDS). The combination of MSDS and LLMs enables our spatial-aware motion optimization, which distills score gradients from pre-trained motion diffusion models, to refine human motion while respecting object and semantic constraints. Unlike prior methods requiring joint training on limited interaction datasets, our zero-shot approach avoids retraining and generalizes to out-of-distribution object aware human motions. Experiments demonstrate that our framework produces natural and physically plausible human motions that respect 3D spatial context, offering a scalable solution for realistic 4D generation.

cs.CV↗

arXiv2025

Group Relative Augmentation for Data Efficient Action Detection

Adapting large Video-Language Models (VLMs) for action detection using only a few examples poses challenges like overfitting and the granularity mismatch between scene-level pre-training and required person-centric understanding. We propose an efficient adaptation strategy combining parameter-efficient tuning (LoRA) with a novel learnable internal feature augmentation. Applied within the frozen VLM backbone using FiLM, these augmentations generate diverse feature variations directly relevant to the task. Additionally, we introduce a group-weighted loss function that dynamically modulates the training contribution of each augmented sample based on its prediction divergence relative to the group average. This promotes robust learning by prioritizing informative yet reasonable augmentations. We demonstrate our method's effectiveness on complex multi-label, multi-person action detection datasets (AVA, MOMA), achieving strong mAP performance and showcasing significant data efficiency for adapting VLMs from limited examples.

cs.CV↗

arXiv2025

Solving Inverse Problems via Diffusion-Based Priors: An Approximation-Free Ensemble Sampling Approach

Diffusion models (DMs) have proven to be effective in modeling high-dimensional distributions, leading to their widespread adoption for representing complex priors in Bayesian inverse problems (BIPs). However, current DM-based posterior sampling methods proposed for solving common BIPs rely on heuristic approximations to the generative process. To exploit the generative capability of DMs and avoid the usage of such approximations, we propose an ensemble-based algorithm that performs posterior sampling without the use of heuristic approximations. Our algorithm is motivated by existing works that combine DM-based methods with the sequential Monte Carlo (SMC) method. By examining how the prior evolves through the diffusion process encoded by the pre-trained score function, we derive a modified partial differential equation (PDE) governing the evolution of the corresponding posterior distribution. This PDE includes a modified diffusion term and a reweighting term, which can be simulated via stochastic weighted particle methods. Theoretically, we prove that the error between the true posterior distribution can be bounded in terms of the training error of the pre-trained score function and the number of particles in the ensemble. Empirically, we validate our algorithm on several inverse problems in imaging to show that our method gives more accurate reconstructions compared to existing DM-based methods.

cs.LG↗

arXiv2025

Reducing Hallucinations of Medical Multimodal Large Language Models with Visual Retrieval-Augmented Generation

Multimodal Large Language Models (MLLMs) have shown impressive performance in vision and text tasks. However, hallucination remains a major challenge, especially in fields like healthcare where details are critical. In this work, we show how MLLMs may be enhanced to support Visual RAG (V-RAG), a retrieval-augmented generation framework that incorporates both text and visual data from retrieved images. On the MIMIC-CXR chest X-ray report generation and Multicare medical image caption generation datasets, we show that Visual RAG improves the accuracy of entity probing, which asks whether a medical entities is grounded by an image. We show that the improvements extend both to frequent and rare entities, the latter of which may have less positive training data. Downstream, we apply V-RAG with entity probing to correct hallucinations and generate more clinically accurate X-ray reports, obtaining a higher RadGraph-F1 score.

cs.CL↗

arXiv2025

Exploring the Role of Reasoning Structures for Constructing Proofs in Multi-Step Natural Language Reasoning with Large Language Models

When performing complex multi-step reasoning tasks, the ability of Large Language Models (LLMs) to derive structured intermediate proof steps is important for ensuring that the models truly perform the desired reasoning and for improving models' explainability. This paper is centred around a focused study: whether the current state-of-the-art generalist LLMs can leverage the structures in a few examples to better construct the proof structures with \textit{in-context learning}. Our study specifically focuses on structure-aware demonstration and structure-aware pruning. We demonstrate that they both help improve performance. A detailed analysis is provided to help understand the results.

cs.CL↗

arXiv2024

Learning Disentangled Equivariant Representation for Explicitly Controllable 3D Molecule Generation

We consider the conditional generation of 3D drug-like molecules with \textit{explicit control} over molecular properties such as drug-like properties (e.g., Quantitative Estimate of Druglikeness or Synthetic Accessibility score) and effectively binding to specific protein sites. To tackle this problem, we propose an E(3)-equivariant Wasserstein autoencoder and factorize the latent space of our generative model into two disentangled aspects: molecular properties and the remaining structural context of 3D molecules. Our model ensures explicit control over these molecular attributes while maintaining equivariance of coordinate representation and invariance of data likelihood. Furthermore, we introduce a novel alignment-based coordinate loss to adapt equivariant networks for auto-regressive de-novo 3D molecule generation from scratch. Extensive experiments validate our model's effectiveness on property-guided and context-guided molecule generation, both for de-novo 3D molecule design and structure-based drug discovery against protein targets.

cs.LG↗

arXiv2024

Exploiting VLM Localizability and Semantics for Open Vocabulary Action Detection

Action detection aims to detect (recognize and localize) human actions spatially and temporally in videos. Existing approaches focus on the closed-set setting where an action detector is trained and tested on videos from a fixed set of action categories. However, this constrained setting is not viable in an open world where test videos inevitably come beyond the trained action categories. In this paper, we address the practical yet challenging Open-Vocabulary Action Detection (OVAD) problem. It aims to detect any action in test videos while training a model on a fixed set of action categories. To achieve such an open-vocabulary capability, we propose a novel method OpenMixer that exploits the inherent semantics and localizability of large vision-language models (VLM) within the family of query-based detection transformers (DETR). Specifically, the OpenMixer is developed by spatial and temporal OpenMixer blocks (S-OMB and T-OMB), and a dynamically fused alignment (DFA) module. The three components collectively enjoy the merits of strong generalization from pre-trained VLMs and end-to-end learning from DETR design. Moreover, we established OVAD benchmarks under various settings, and the experimental results show that the OpenMixer performs the best over baselines for detecting seen and unseen actions. We release the codes, models, and dataset splits at https://github.com/Cogito2012/OpenMixer.

cs.CV↗

arXiv2024

Variational methods for Learning Multilevel Genetic Algorithms using the Kantorovich Monad

Levels of selection and multilevel evolutionary processes are essential concepts in evolutionary theory, and yet there is a lack of common mathematical models for these core ideas. Here, we propose a unified mathematical framework for formulating and optimizing multilevel evolutionary processes and genetic algorithms over arbitrarily many levels based on concepts from category theory and population genetics. We formulate a multilevel version of the Wright-Fisher process using this approach, and we show that this model can be analyzed to clarify key features of multilevel selection. Particularly, we derive an extended multilevel probabilistic version of Price's Equation via the Kantorovich Monad, and we use this to characterize regimes of parameter space within which selection acts antagonistically or cooperatively across levels. Finally, we show how our framework can provide a unified setting for learning genetic algorithms (GAs), and we show how we can use a Variational Optimization and a multi-level analogue of coalescent analysis to fit multilevel GAs to simulated data.

q-bio.PE↗

arXiv2024

Learning to Localize Actions in Instructional Videos with LLM-Based Multi-Pathway Text-Video Alignment

Learning to localize temporal boundaries of procedure steps in instructional videos is challenging due to the limited availability of annotated large-scale training videos. Recent works focus on learning the cross-modal alignment between video segments and ASR-transcripted narration texts through contrastive learning. However, these methods fail to account for the alignment noise, i.e., irrelevant narrations to the instructional task in videos and unreliable timestamps in narrations. To address these challenges, this work proposes a novel training framework. Motivated by the strong capabilities of Large Language Models (LLMs) in procedure understanding and text summarization, we first apply an LLM to filter out task-irrelevant information and summarize task-related procedure steps (LLM-steps) from narrations. To further generate reliable pseudo-matching between the LLM-steps and the video for training, we propose the Multi-Pathway Text-Video Alignment (MPTVA) strategy. The key idea is to measure alignment between LLM-steps and videos via multiple pathways, including: (1) step-narration-video alignment using narration timestamps, (2) direct step-to-video alignment based on their long-term semantic similarity, and (3) direct step-to-video alignment focusing on short-term fine-grained semantic similarity learned from general video domains. The results from different pathways are fused to generate reliable pseudo step-video matching. We conducted extensive experiments across various tasks and problem settings to evaluate our proposed method. Our approach surpasses state-of-the-art methods in three downstream tasks: procedure step grounding, step localization, and narration grounding by 5.9\%, 3.1\%, and 2.8\%.

cs.CV↗

arXiv2024

Planner3D: LLM-enhanced graph prior meets 3D indoor scene explicit regularization

Compositional 3D scene synthesis has diverse applications across a spectrum of industries such as robotics, films, and video games, as it closely mirrors the complexity of real-world multi-object environments. Conventional works typically employ shape retrieval based frameworks which naturally suffer from limited shape diversity. Recent progresses have been made in object shape generation with generative models such as diffusion models, which increases the shape fidelity. However, these approaches separately treat 3D shape generation and layout generation. The synthesized scenes are usually hampered by layout collision, which suggests that the scene-level fidelity is still under-explored. In this paper, we aim at generating realistic and reasonable 3D indoor scenes from scene graph. To enrich the priors of the given scene graph inputs, large language model is utilized to aggregate the global-wise features with local node-wise and edge-wise features. With a unified graph encoder, graph features are extracted to guide joint layout-shape generation. Additional regularization is introduced to explicitly constrain the produced 3D layouts. Benchmarked on the SG-FRONT dataset, our method achieves better 3D scene synthesis, especially in terms of scene-level fidelity. The source code will be released after publication.

cs.CV↗

arXiv2024

Why Not Use Your Textbook? Knowledge-Enhanced Procedure Planning of Instructional Videos

In this paper, we explore the capability of an agent to construct a logical sequence of action steps, thereby assembling a strategic procedural plan. This plan is crucial for navigating from an initial visual observation to a target visual outcome, as depicted in real-life instructional videos. Existing works have attained partial success by extensively leveraging various sources of information available in the datasets, such as heavy intermediate visual observations, procedural names, or natural language step-by-step instructions, for features or supervision signals. However, the task remains formidable due to the implicit causal constraints in the sequencing of steps and the variability inherent in multiple feasible plans. To tackle these intricacies that previous efforts have overlooked, we propose to enhance the capabilities of the agent by infusing it with procedural knowledge. This knowledge, sourced from training procedure plans and structured as a directed weighted graph, equips the agent to better navigate the complexities of step sequencing and its potential variations. We coin our approach KEPP, a novel Knowledge-Enhanced Procedure Planning system, which harnesses a probabilistic procedural knowledge graph extracted from training data, effectively acting as a comprehensive textbook for the training domain. Experimental evaluations across three widely-used datasets under settings of varying complexity reveal that KEPP attains superior, state-of-the-art results while requiring only minimal supervision.

cs.CV↗

arXiv2023

Disentangled Wasserstein Autoencoder for T-Cell Receptor Engineering

In protein biophysics, the separation between the functionally important residues (forming the active site or binding surface) and those that create the overall structure (the fold) is a well-established and fundamental concept. Identifying and modifying those functional sites is critical for protein engineering but computationally non-trivial, and requires significant domain knowledge. To automate this process from a data-driven perspective, we propose a disentangled Wasserstein autoencoder with an auxiliary classifier, which isolates the function-related patterns from the rest with theoretical guarantees. This enables one-pass protein sequence editing and improves the understanding of the resulting sequences and editing actions involved. To demonstrate its effectiveness, we apply it to T-cell receptors (TCRs), a well-studied structure-function case. We show that our method can be used to alter the function of TCRs without changing the structural backbone, outperforming several competing methods in generation quality and efficiency, and requiring only 10% of the running time needed by baseline models. To our knowledge, this is the first approach that utilizes disentangled representations for TCR engineering.

q-bio.BM↗