arXiv subjects

Mehran Kardar

Publications and source records attributed to Mehran Kardar.

At least 37 records · Page 2Linked to original sources

arXiv2023

Competition on the edge of an expanding population

In growing populations, the fate of mutations depends on their competitive ability against the ancestor and their ability to colonize new territory. Here we present a theory that integrates both aspects of mutant fitness by coupling the classic description of one-dimensional competition (Fisher equation) to the minimal model of front shape (KPZ equation). We solved these equations and found three regimes, which are controlled solely by the expansion rates, solely by the competitive abilities, or by both. Collectively, our results provide a simple framework to study spatial competition.

q-bio.PE↗

arXiv2022

Equilibrium forces on non-reciprocal materials

We discuss and analyze the properties of Casimir forces acting between nonreciprocal objects in thermal equilibrium. By starting from the fluctuation-dissipation theorem and splitting the force into those arising from individual sources, we show that if all temperatures are equal, the resulting force is reciprocal and is derivable as the gradient of a Casimir (free) energy. While the expression for the free energy is identical to the one for reciprocal objects, there are several distinct features: To leading order in reflections, the free energy can be decomposed as the sum of two terms, the first corresponding to two reciprocal objects, and the second corresponding to two anti-reciprocal objects. The first term is negative and typically yields attraction, while the second can have either sign. For the case of two objects that are each other's mirror images, the second term is positive and yields repulsion. The sum of terms can lead to overall repulsive forces, in agreement with previous observations. Stable configurations, ruled out for reciprocal cases, appear possible for nonreciprocal objects. We show that for three objects, a three-body free energy exists, indicating that previously found persistent heat currents in situations of three objects cannot be used to produce persistent torques.

quant-ph↗

arXiv2022

Something Can Come of Nothing: Surface Approaches to Quantum Fluctuations and the Casimir Force

The Casimir force provides a striking example of the effects of quantum fluctuations in a mesoscopic system. Because it arises from the objects' electromagnetic response, the necessary calculations in quantum field theory are most naturally expressed in terms of electromagnetic scattering from each object. In this review we illustrate a variety of such techniques, with a focus on those that can be expressed in terms of surface effects, including both idealized boundary conditions and their physical realization in terms of material properties.

quant-ph↗

arXiv2022

Passive objects in confined active fluids: a localization transition

We study how walls confining active fluids interact with asymmetric passive objects placed in their bulk. We show that the objects experience non-conservative long-ranged forces mediated by the active bath. To leading order, these forces can be computed using a generalized image theorem. The walls repel asymmetric objects, irrespective of their microscopic properties or their orientations. For circular cavities, we demonstrate how this may lead to the localization of asymmetric objects in the center of the cavity, something impossible for symmetric ones.

cond-mat.stat-mech↗

arXiv2021

Disordered boundaries destroy bulk phase separation in scalar active matter

We show that disordered boundaries destroy bulk phase separation in scalar active systems in dimension $d<d_c=3$. This is in strong contrast with the equilibrium case where boundaries have no impact on the bulk of phase-separated systems. The underlying mechanism is revealed by considering a localized deformation of an otherwise flat wall, from which the case of a disordered boundary can be inferred. We find long-ranged correlations of the density field as well as a cascade of eddies which we show prevent bulk phase separation in low enough dimensions. The results are derived for dilute systems as well as in the presence of interactions, under the sole condition that the density field is the unique hydrodynamic mode. Our theoretical calculations are validated by numerical simulations of microscopic active systems.

cond-mat.soft↗

arXiv2021

A Seascape Origin of Richards Growth

First proposed as an empirical rule over half a century ago, the Richards growth equation has been frequently invoked in population modeling and pandemic forecasting. Central to this model is the advent of a fractional exponent $γ$, typically fitted to the data. While various motivations for this non-analytical form have been proposed, it is still considered foremost an empirical fitting procedure. Here, we find that Richards-like growth laws emerge naturally from generic analytical growth rules in a distributed population, upon inclusion of {\bf (i)} migration (spatial diffusion) amongst different locales, and {\bf (ii)} stochasticity in the growth rate, also known as "seascape noise." The latter leads to a wide (power-law) distribution in local population number that, while smoothened through the former, can still result in a fractional growth law for the overall population. This justification of the Richards growth law thus provides a testable connection to the distribution of constituents of the population.

q-bio.PE↗

arXiv2021

Near field propulsion forces from nonreciprocal media

Arguments based on symmetry and thermodynamics may suggest the existence of a ratchet-like lateral Casimir force between two plates at different temperatures and with broken inversion symmetry. We find that this is not sufficient, and at least one plate must be made of nonreciprocal material. This setup operates as a heat engine by transforming heat radiation into mechanical force. Although the ratio of the lateral force to heat transfer in the near field regime diverges inversely with the plates separation, $d$, an Onsager symmetry, which we extend to nonreciprocal plates, limits the engine efficiency to the Carnot value $η_c$. The optimal velocity of operation in the far field is of the order of $cη_c$, where $c$ is the speed of light. In the near field regime, this velocity can be reduced to the order of $\barωd η_c$, where $\barω$ is a typical material frequency.

quant-ph↗

arXiv2020

Disorder-Induced Long-Ranged Correlations in Scalar Active Matter

We study the impact of a random quenched potentials and torques on scalar active matter. Microscopic simulations reveal that motility-induced phase separation is replaced in two-dimensions by an asymptotically homogeneous phase with anomalous long-ranged correlations and non-vanishing steady-state currents. Using a combination of phenomenological models and a field-theoretical treatment, we show the existence of a lower-critical dimension, $d_c=4$, below which phase separation is only observed for systems smaller than an Imry-Ma length-scale. We identify a weak-disorder regime in which the structure factor scales as $S(q) \sim 1/q^2$ which accounts for our numerics. In $d=2$ we predict that, at larger scales, the behaviour should cross over to a strong-disorder regime. In $d>2$, these two regimes exist separately, depending on the strength of the potential.

cond-mat.stat-mech↗

arXiv2020

Population Extinction on a Random Fitness Seascape

Models of population growth and extinction are an increasingly popular subject of study. However, consequences of stochasticity and noise in shaping distributions and outcomes are not sufficiently explored. Here we consider a distributed population with logistic growth at each location, subject to "seascape" noise, wherein the population's fitness randomly varies with {\it location and time}. Despite its simplicity, the model actually incorporates variants of directed percolation, and directed polymers in random media, within a mean-field perspective. Probability distributions of the population can be computed self-consistently; and the extinction transition is shown to exhibit novel critical behavior with exponents dependent on the ratio of the strengths of migration and noise amplitudes. The results are compared and contrasted with the more conventional choice of demographic noise due to stochastic changes in reproduction.

cond-mat.stat-mech↗

arXiv2020

Studying viral populations with tools from quantum spin chains

We study Eigen's model of quasi-species, characterized by sequences that replicate with a specified fitness and mutate independently at single sites. The evolution of the population vector in time is then closely related to that of quantum spins in imaginary time. We employ multiple perspectives and tools from interacting quantum systems to examine growth and collapse of realistic viral populations, specifically certain HIV proteins. All approaches used, including the simplest perturbation theory, give consistent results.

cond-mat.stat-mech↗

arXiv2019

Activated diffusiophoresis

Perturbations of fluid media can give rise to non-equilibrium dynamics, which may in turn cause motion of immersed inclusions. We consider perturbations ("activations") that are local in space and time, of a fluid density which is conserved, and study the resulting diffusiophoretic phenomena that emerge at a large distance. Specifically, we consider cases where the perturbations propagate diffusively, providing examples from passive and active matter for which this is expected to be the case. Activations can, for instance, be realized by sudden and local changes in interaction potentials of the medium, or by local changes of its activity. Various analytical results are provided for the case of confinement by two parallel walls. We investigate the possibility of extracting work from inclusions which are moving through the activated fluid. Further, we show that a time-dependent density profile, created via suitable activation protocols, allows for conveyance of inclusions along controlled and stable trajectories. In contrast, in states with a steady density, inclusions cannot be held at stable positions, reminiscent of Earnshaw's theorem of electrostatics. We expect these findings to be applicable in a range of experimental systems.

cond-mat.stat-mech↗

arXiv2019

Pinning of Diffusional Patterns by Non-Uniform Curvature

Diffusion-driven patterns appear on curved surfaces in many settings, initiated by unstable modes of an underlying Laplacian operator. On a flat surface or perfect sphere, the patterns are degenerate, reflecting translational/rotational symmetry. Deformations, e.g. by a bulge or indentation, break symmetry and can pin a pattern. We adapt methods of conformal mapping and perturbation theory to examine how curvature inhomogeneities select and pin patterns, and confirm the results numerically. The theory provides an analogy to quantum mechanics in a geometry-dependent potential and yields intuitive implications for cell membranes, tissues, thin films, and noise-induced quasipatterns.

cond-mat.soft↗

arXiv2019

Percolation of sites not removed by a random walker in $d$ dimensions

How does removal of sites by a random walk lead to blockage of percolation? To study this problem of correlated site percolation, we consider a random walk (RW) of $N=uL^d$ steps on a $d$-dimensional hypercubic lattice of size $L^d$ (with periodic boundaries). We systematically explore dependence of the probability $Π_d(L,u)$ of percolation (existence of a spanning cluster) of sites not removed by the RW on $L$ and $u$. The concentration of unvisited sites decays exponentially with increasing $u$, while the visited sites are highly correlated -- their correlations decaying with the distance $r$ as $1/r^{d-2}$ (in $d>2$). Upon increasing $L$, the percolation probability $Π_d(L,u)$ approaches a step function, jumping from 1 to 0 when $u$ crosses a percolation threshold $u_c$ that is close to 3 for all $3\le d\le6$. Within numerical accuracy, the correlation length associated with percolation diverges with exponents consistent with $ν=2/(d-2)$. There is no percolation threshold at the lower critical dimension of $d=2$, with the percolation probability approaching a smooth function $Π_2(\infty,u)>0$.

cond-mat.stat-mech↗

arXiv2019

Ramifications of disorder on active particles in one dimension

The effects of quenched disorder on a single and many active run-and-tumble particles is studied in one dimension. For a single particle, we consider both the steady-state distribution and the particle's dynamics subject to disorder in three parameters: a bounded external potential, the particle's speed, and its tumbling rate. We show that in the case of a disordered potential, the behavior is like an equilibrium particle diffusing on a random force landscape, implying a dynamics that is logarithmically slow in time. In the situations of disorder in the speed or tumbling rate, we find that the particle generically exhibits diffusive motion, although particular choices of the disorder may lead to anomalous diffusion. Based on the single-particle results, we find that in a system with many interacting particles, disorder in the potential leads to strong clustering. We characterize the clustering in two different regimes depending on the system size and show that the mean cluster size scales with the system size, in contrast to non-disordered systems.

cond-mat.stat-mech↗

arXiv2019

Bacterial range expansions on a growing front: Roughness, Fixation, and Directed Percolation

Directed Percolation (DP) is a classic model for nonequilibrium phase transitions into a single absorbing state (fixation). It has been extensively studied by analytical and numerical techniques in diverse contexts. Recently, DP has appeared as a generic model for the evolutionary/ecological dynamics of competing bacterial populations. Range expansion -- the stochastic reproduction of bacteria competing for space to be occupied by their progeny -- leads to a fluctuating and rough growth front, which is known from experiment and simulation to affect the underlying critical behavior of the DP transition. In this work, we employ symmetry arguments to construct a pair of non-linear stochastic partial differential equations describing the co-evolution of surface roughness with the composition field of DP. Macroscopic manifestations (phenomenology) of these equations on growth patterns and genealogical tracks of range expansion are discussed; followed by a renormalization group analysis of possible scaling behaviors at the DP transition.

cond-mat.stat-mech↗

arXiv2019

Pinning of Diffusional Instabilities by Non-Uniform Curvature

Turing patterns emerge from a spatially uniform state following a linear instability driven by diffusion. Features of the eventual pattern (stabilized by non-linearities) are already present in the initial unstable modes. On a uniform flat surface or perfect sphere, the unstable modes and final patterns are degenerate, reflecting translational/rotational symmetry. This symmetry can be broken, e.g. by a bump on a flat substrate or by deforming a sphere. As the diffusion operator on a two dimensional manifold depends on the underlying curvature, the degeneracy of the initial unstable mode is similarly reduced. Different shapes can pin different modes. We adapt methods of conformal mapping and perturbation theory to analytically examine how bumps and ripples entrain modes of the diffusion operator on cylinders and spheres. We confirm these results numerically, and provide closed form expressions that describe how non-uniformities in curvature pin diffusion-driven instabilities and the resulting patterns.

cond-mat.soft↗

arXiv2019

Pair Dispersion in Dilute Suspension of Active Swimmers

Ensembles of biological and artificial microswimmers produce long-range velocity fields with strong nonequilibrium fluctuations, which result in dramatic increase diffusivity of embedded particles (tracers). While such enhanced diffusivity may point to enhanced mixing of the fluid, a rigorous quantification of the mixing efficiency requires analysis of pair dispersion of tracers, rather than simple one-particle diffusivity. Here, we calculate analytically the scale-dependent coefficient of relative diffusivity of passive tracers embedded in a dilute suspension of run-and-tumble microswimmers. Although each tracer is subject to strong fluctuations resulting in large absolute diffusivity, the small-scale relative dispersion is suppressed due to the correlations in fluid velocity which are relevant when the inter-tracers separation is below the persistence length of the swimmers motion. Our results suggest that the reorientation of swimming direction plays an important role in biological mixing and should be accounted in design of potential active matter devices capable of effective fluid mixing at microscale.

cond-mat.soft↗

arXiv2018

Evolution in range expansions with competition at rough boundaries

When a biological population expands into new territory, genetic drift develops an enormous influence on evolution at the propagating front. In such range expansion processes, fluctuations in allele frequencies occur through stochastic \textit{spatial} wandering of both genetic lineages and the boundaries between genetically segregated sectors. Laboratory experiments on microbial range expansions have shown that this stochastic wandering, transverse to the front, is superdiffusive due to the front's growing roughness, implying much faster loss of genetic diversity than predicted by simple flat front diffusive models. We study the evolutionary consequences of this superdiffusive wandering using two complementary numerical models of range expansions: the stepping stone model, and a new interpretation of the model of directed paths in random media, in the context of a roughening population front. Through these approaches we compute statistics for the times since common ancestry for pairs of individuals with a given spatial separation at the front, and we explore how environmental heterogeneities can locally suppress these superdiffusive fluctuations.

physics.bio-ph↗