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Miguel Castelo-Branco

Publications and source records attributed to Miguel Castelo-Branco.

6 recordsLinked to original sources

Analysis of Motor Signatures of Social Adaptation in Autism for Efficient Human-Centric Systems

Dance imitation integrates motor planning, sensorimotor integration, and social cognition, offering a sensitive framework to characterize motor behavior in autism. In this work, we explore a computational analysis framework to identify potential biomarkers that allow the design and development of improved medical and human-machine systems. We analyzed 3D motion capture data from autistic and neurotypical adults performing dance imitation under solo and socially-framed duo conditions. Methodologically, using Dynamic Time Warping, we quantified movement consistency and propose the Social Context Sensitivity Index (SCSI) to measure modulation of variability by social framing. These features were then used on a classifier to discriminate subjects into autistic or neurotypical groups. Results show that neurotypical adults exhibited increased movement variability in socially-framed imitation, especially in upper and lower limbs, whereas autistic adults maintained consistent movement across contexts. Classification achieved 79.2% balanced accuracy in distinguishing groups. These findings suggest that social context sensitivity in motor imitation constitutes a robust biomarker of autism-related motor behavior, highlighting the importance of social modulation in motor assessments and informing the development of inclusive human-centric technologies.

cs.HC

Self-Emotion-Mediated Exploration in Artificial Intelligence Mirrors: Findings from Cognitive Psychology

Background: Exploration of the physical environment is an indispensable precursor to information acquisition and knowledge consolidation for living organisms. Yet, current artificial intelligence models lack these autonomy capabilities during training, hindering their adaptability. This work proposes a learning framework for artificial agents to obtain an intrinsic exploratory drive, based on epistemic and achievement emotions triggered during data observation. Methods: This study proposes a dual-module reinforcement framework, where data analysis scores dictate pride or surprise, in accordance with psychological studies on humans. A correlation between these states and exploration is then optimized for agents to meet their learning goals. Results: Causal relationships between states and exploration are demonstrated by the majority of agents. A 15.4\% mean increase is noted for surprise, with a 2.8\% mean decrease for pride. Resulting correlations of $ρ_{surprise}=0.461$ and $ρ_{pride}=-0.237$ are obtained, mirroring previously reported human behavior. Conclusions: These findings lead to the conclusion that bio-inspiration for AI development can be of great use. This can incur benefits typically found in living beings, such as autonomy. Further, it empirically shows how AI methodologies can corroborate human behavioral findings, showcasing major interdisciplinary importance. Ramifications are discussed.

cs.AI

Resistive Plate Chambers for brain PET imaging and particle tracking and timing (TOF-tracker)

In this work we explore readout architectures for the simultaneous high-resolution timing and bidimensional tracking of charged particles with Resistive Plate Chambers (TOF-tracker) and for the accurate detection of gamma rays for PET imaging. On 625 $cm^2$ of active area we obtained a time resolution of 61 ps $σ$ and bidimensional position resolution below 150 $μ$m $σ$ for the tracking and timing of charged particles from cosmic rays. An intrinsic precision of 0.49 mm FWHM was determined for the localization of a small $β^+$ source via the detection of its annihilation radiation.

physics.ins-det

An RPC-PET brain scanner demonstrator: first results

We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40 gas gaps with 3D location of the interaction point of the photon. Besides other imagery, we show that the reconstructed image resolution, as evaluated by a hot-rod phantom, is sub-millimetric, which is beyond the state-of-the-art of the standard PET technology for this application.

physics.ins-det

A Deep Learning-based Integrated Framework for Quality-aware Undersampled Cine Cardiac MRI Reconstruction and Analysis

Cine cardiac magnetic resonance (CMR) imaging is considered the gold standard for cardiac function evaluation. However, cine CMR acquisition is inherently slow and in recent decades considerable effort has been put into accelerating scan times without compromising image quality or the accuracy of derived results. In this paper, we present a fully-automated, quality-controlled integrated framework for reconstruction, segmentation and downstream analysis of undersampled cine CMR data. The framework enables active acquisition of radial k-space data, in which acquisition can be stopped as soon as acquired data are sufficient to produce high quality reconstructions and segmentations. This results in reduced scan times and automated analysis, enabling robust and accurate estimation of functional biomarkers. To demonstrate the feasibility of the proposed approach, we perform realistic simulations of radial k-space acquisitions on a dataset of subjects from the UK Biobank and present results on in-vivo cine CMR k-space data collected from healthy subjects. The results demonstrate that our method can produce quality-controlled images in a mean scan time reduced from 12 to 4 seconds per slice, and that image quality is sufficient to allow clinically relevant parameters to be automatically estimated to within 5% mean absolute difference.

eess.IV

Quality-aware Cine Cardiac MRI Reconstruction and Analysis from Undersampled k-space Data

Cine cardiac MRI is routinely acquired for the assessment of cardiac health, but the imaging process is slow and typically requires several breath-holds to acquire sufficient k-space profiles to ensure good image quality. Several undersampling-based reconstruction techniques have been proposed during the last decades to speed up cine cardiac MRI acquisition. However, the undersampling factor is commonly fixed to conservative values before acquisition to ensure diagnostic image quality, potentially leading to unnecessarily long scan times. In this paper, we propose an end-to-end quality-aware cine short-axis cardiac MRI framework that combines image acquisition and reconstruction with downstream tasks such as segmentation, volume curve analysis and estimation of cardiac functional parameters. The goal is to reduce scan time by acquiring only a fraction of k-space data to enable the reconstruction of images that can pass quality control checks and produce reliable estimates of cardiac functional parameters. The framework consists of a deep learning model for the reconstruction of 2D+t cardiac cine MRI images from undersampled data, an image quality-control step to detect good quality reconstructions, followed by a deep learning model for bi-ventricular segmentation, a quality-control step to detect good quality segmentations and automated calculation of cardiac functional parameters. To demonstrate the feasibility of the proposed approach, we perform simulations using a cohort of selected participants from the UK Biobank (n=270), 200 healthy subjects and 70 patients with cardiomyopathies. Our results show that we can produce quality-controlled images in a scan time reduced from 12 to 4 seconds per slice, enabling reliable estimates of cardiac functional parameters such as ejection fraction within 5% mean absolute error.

eess.IV