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Milind Tambe

Publications and source records attributed to Milind Tambe.

At least 127 records · Page 7Linked to original sources

Clinical trial of an AI-augmented intervention for HIV prevention in youth experiencing homelessness

Youth experiencing homelessness (YEH) are subject to substantially greater risk of HIV infection, compounded both by their lack of access to stable housing and the disproportionate representation of youth of marginalized racial, ethnic, and gender identity groups among YEH. A key goal for health equity is to improve adoption of protective behaviors in this population. One promising strategy for intervention is to recruit peer leaders from the population of YEH to promote behaviors such as condom usage and regular HIV testing to their social contacts. This raises a computational question: which youth should be selected as peer leaders to maximize the overall impact of the intervention? We developed an artificial intelligence system to optimize such social network interventions in a community health setting. We conducted a clinical trial enrolling 713 YEH at drop-in centers in a large US city. The clinical trial compared interventions planned with the algorithm to those where the highest-degree nodes in the youths' social network were recruited as peer leaders (the standard method in public health) and to an observation-only control group. Results from the clinical trial show that youth in the AI group experience statistically significant reductions in key risk behaviors for HIV transmission, while those in the other groups do not. This provides, to our knowledge, the first empirical validation of the usage of AI methods to optimize social network interventions for health. We conclude by discussing lessons learned over the course of the project which may inform future attempts to use AI in community-level interventions.

cs.SI↗

Automatically Learning Compact Quality-aware Surrogates for Optimization Problems

Solving optimization problems with unknown parameters often requires learning a predictive model to predict the values of the unknown parameters and then solving the problem using these values. Recent work has shown that including the optimization problem as a layer in the model training pipeline results in predictions of the unobserved parameters that lead to higher decision quality. Unfortunately, this process comes at a large computational cost because the optimization problem must be solved and differentiated through in each training iteration; furthermore, it may also sometimes fail to improve solution quality due to non-smoothness issues that arise when training through a complex optimization layer. To address these shortcomings, we learn a low-dimensional surrogate model of a large optimization problem by representing the feasible space in terms of meta-variables, each of which is a linear combination of the original variables. By training a low-dimensional surrogate model end-to-end, and jointly with the predictive model, we achieve: i) a large reduction in training and inference time; and ii) improved performance by focusing attention on the more important variables in the optimization and learning in a smoother space. Empirically, we demonstrate these improvements on a non-convex adversary modeling task, a submodular recommendation task and a convex portfolio optimization task.

cs.LG↗

Tracking disease outbreaks from sparse data with Bayesian inference

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods exist, they work best at coarse-grained national or state scales with abundant data, and struggle to accommodate the partial observability and sparse data common at finer scales (e.g., individual schools or towns). For example, case counts may be sparse when only a small fraction of infections are caught by a testing program. Or, whether an infected individual tests positive may depend on the kind of test and the point in time when they are tested. We propose a Bayesian framework which accommodates partial observability in a principled manner. Our model places a Gaussian process prior over the unknown reproduction number at each time step and models observations sampled from the distribution of a specific testing program. For example, our framework can accommodate a variety of kinds of tests (viral RNA, antibody, antigen, etc.) and sampling schemes (e.g., longitudinal or cross-sectional screening). Inference in this framework is complicated by the presence of tens or hundreds of thousands of discrete latent variables. To address this challenge, we propose an efficient stochastic variational inference method which relies on a novel gradient estimator for the variational objective. Experimental results for an example motivated by COVID-19 show that our method produces an accurate and well-calibrated posterior, while standard methods for estimating the reproduction number can fail badly.

stat.ME↗

Preliminary Results from a Peer-Led, Social Network Intervention, Augmented by Artificial Intelligence to Prevent HIV among Youth Experiencing Homelessness

Each year, there are nearly 4 million youth experiencing homelessness (YEH) in the United States with HIV prevalence ranging from 3 to 11.5%. Peer change agent (PCA) models for HIV prevention have been used successfully in many populations, but there have been notable failures. In recent years, network interventionists have suggested that these failures could be attributed to PCA selection procedures. The change agents themselves who are selected to do the PCA work can often be as important as the messages they convey. To address this concern, we tested a new PCA intervention for YEH, with three arms: (1) an arm using an artificial intelligence (AI) planning algorithm to select PCA, (2) a popularity arm--the standard PCA approach--operationalized as highest degree centrality (DC), and (3) an observation only comparison group (OBS). PCA models that promote HIV testing, HIV knowledge, and condom use are efficacious for YEH. Both the AI and DC arms showed improvements over time. AI-based PCA selection led to better outcomes and increased the speed of intervention effects. Specifically, the changes in behavior observed in the AI arm occurred by 1 month, but not until 3 months in the DC arm. Given the transient nature of YEH and the high risk for HIV infection, more rapid intervention effects are desirable.

cs.SI↗

Missed calls, Automated Calls and Health Support: Using AI to improve maternal health outcomes by increasing program engagement

India accounts for 11% of maternal deaths globally where a woman dies in childbirth every fifteen minutes. Lack of access to preventive care information is a significant problem contributing to high maternal morbidity and mortality numbers, especially in low-income households. We work with ARMMAN, a non-profit based in India, to further the use of call-based information programs by early-on identifying women who might not engage on these programs that are proven to affect health parameters positively.We analyzed anonymized call-records of over 300,000 women registered in an awareness program created by ARMMAN that uses cellphone calls to regularly disseminate health related information. We built robust deep learning based models to predict short term and long term dropout risk from call logs and beneficiaries' demographic information. Our model performs 13% better than competitive baselines for short-term forecasting and 7% better for long term forecasting. We also discuss the applicability of this method in the real world through a pilot validation that uses our method to perform targeted interventions.

cs.CY↗

Collapsing Bandits and Their Application to Public Health Interventions

We propose and study Collpasing Bandits, a new restless multi-armed bandit (RMAB) setting in which each arm follows a binary-state Markovian process with a special structure: when an arm is played, the state is fully observed, thus "collapsing" any uncertainty, but when an arm is passive, no observation is made, thus allowing uncertainty to evolve. The goal is to keep as many arms in the "good" state as possible by planning a limited budget of actions per round. Such Collapsing Bandits are natural models for many healthcare domains in which workers must simultaneously monitor patients and deliver interventions in a way that maximizes the health of their patient cohort. Our main contributions are as follows: (i) Building on the Whittle index technique for RMABs, we derive conditions under which the Collapsing Bandits problem is indexable. Our derivation hinges on novel conditions that characterize when the optimal policies may take the form of either "forward" or "reverse" threshold policies. (ii) We exploit the optimality of threshold policies to build fast algorithms for computing the Whittle index, including a closed-form. (iii) We evaluate our algorithm on several data distributions including data from a real-world healthcare task in which a worker must monitor and deliver interventions to maximize their patients' adherence to tuberculosis medication. Our algorithm achieves a 3-order-of-magnitude speedup compared to state-of-the-art RMAB techniques while achieving similar performance.

cs.LG↗

End-to-End Game-Focused Learning of Adversary Behavior in Security Games

Stackelberg security games are a critical tool for maximizing the utility of limited defense resources to protect important targets from an intelligent adversary. Motivated by green security, where the defender may only observe an adversary's response to defense on a limited set of targets, we study the problem of learning a defense that generalizes well to a new set of targets with novel feature values and combinations. Traditionally, this problem has been addressed via a two-stage approach where an adversary model is trained to maximize predictive accuracy without considering the defender's optimization problem. We develop an end-to-end game-focused approach, where the adversary model is trained to maximize a surrogate for the defender's expected utility. We show both in theory and experimental results that our game-focused approach achieves higher defender expected utility than the two-stage alternative when there is limited data.

cs.GT↗

Game Theory on the Ground: The Effect of Increased Patrols on Deterring Poachers

Applications of artificial intelligence for wildlife protection have focused on learning models of poacher behavior based on historical patterns. However, poachers' behaviors are described not only by their historical preferences, but also their reaction to ranger patrols. Past work applying machine learning and game theory to combat poaching have hypothesized that ranger patrols deter poachers, but have been unable to find evidence to identify how or even if deterrence occurs. Here for the first time, we demonstrate a measurable deterrence effect on real-world poaching data. We show that increased patrols in one region deter poaching in the next timestep, but poachers then move to neighboring regions. Our findings offer guidance on how adversaries should be modeled in realistic game-theoretic settings.

cs.CY↗

Exploring Algorithmic Fairness in Robust Graph Covering Problems

Fueled by algorithmic advances, AI algorithms are increasingly being deployed in settings subject to unanticipated challenges with complex social effects. Motivated by real-world deployment of AI driven, social-network based suicide prevention and landslide risk management interventions, this paper focuses on robust graph covering problems subject to group fairness constraints. We show that, in the absence of fairness constraints, state-of-the-art algorithms for the robust graph covering problem result in biased node coverage: they tend to discriminate individuals (nodes) based on membership in traditionally marginalized groups. To mitigate this issue, we propose a novel formulation of the robust graph covering problem with group fairness constraints and a tractable approximation scheme applicable to real-world instances. We provide a formal analysis of the price of group fairness (PoF) for this problem, where we show that uncertainty can lead to greater PoF. We demonstrate the effectiveness of our approach on several real-world social networks. Our method yields competitive node coverage while significantly improving group fairness relative to state-of-the-art methods.

math.OC↗

Influence maximization in unknown social networks: Learning Policies for Effective Graph Sampling

A serious challenge when finding influential actors in real-world social networks is the lack of knowledge about the structure of the underlying network. Current state-of-the-art methods rely on hand-crafted sampling algorithms; these methods sample nodes and their neighbours in a carefully constructed order and choose opinion leaders from this discovered network to maximize influence spread in the (unknown) complete network. In this work, we propose a reinforcement learning framework for network discovery that automatically learns useful node and graph representations that encode important structural properties of the network. At training time, the method identifies portions of the network such that the nodes selected from this sampled subgraph can effectively influence nodes in the complete network. The realization of such transferable network structure based adaptable policies is attributed to the meticulous design of the framework that encodes relevant node and graph signatures driven by an appropriate reward scheme. We experiment with real-world social networks from four different domains and show that the policies learned by our RL agent provide a 10-36% improvement over the current state-of-the-art method.

cs.SI↗

End to end learning and optimization on graphs

Real-world applications often combine learning and optimization problems on graphs. For instance, our objective may be to cluster the graph in order to detect meaningful communities (or solve other common graph optimization problems such as facility location, maxcut, and so on). However, graphs or related attributes are often only partially observed, introducing learning problems such as link prediction which must be solved prior to optimization. Standard approaches treat learning and optimization entirely separately, while recent machine learning work aims to predict the optimal solution directly from the inputs. Here, we propose an alternative decision-focused learning approach that integrates a differentiable proxy for common graph optimization problems as a layer in learned systems. The main idea is to learn a representation that maps the original optimization problem onto a simpler proxy problem that can be efficiently differentiated through. Experimental results show that our ClusterNet system outperforms both pure end-to-end approaches (that directly predict the optimal solution) and standard approaches that entirely separate learning and optimization. Code for our system is available at https://github.com/bwilder0/clusternet.

cs.LG↗

Solving Online Threat Screening Games using Constrained Action Space Reinforcement Learning

Large-scale screening for potential threats with limited resources and capacity for screening is a problem of interest at airports, seaports, and other ports of entry. Adversaries can observe screening procedures and arrive at a time when there will be gaps in screening due to limited resource capacities. To capture this game between ports and adversaries, this problem has been previously represented as a Stackelberg game, referred to as a Threat Screening Game (TSG). Given the significant complexity associated with solving TSGs and uncertainty in arrivals of customers, existing work has assumed that screenees arrive and are allocated security resources at the beginning of the time window. In practice, screenees such as airport passengers arrive in bursts correlated with flight time and are not bound by fixed time windows. To address this, we propose an online threat screening model in which screening strategy is determined adaptively as a passenger arrives while satisfying a hard bound on acceptable risk of not screening a threat. To solve the online problem with a hard bound on risk, we formulate it as a Reinforcement Learning (RL) problem with constraints on the action space (hard bound on risk). We provide a novel way to efficiently enforce linear inequality constraints on the action output in Deep Reinforcement Learning. We show that our solution allows us to significantly reduce screenee wait time while guaranteeing a bound on risk.

cs.GT↗

Stay Ahead of Poachers: Illegal Wildlife Poaching Prediction and Patrol Planning Under Uncertainty with Field Test Evaluations

Illegal wildlife poaching threatens ecosystems and drives endangered species toward extinction. However, efforts for wildlife protection are constrained by the limited resources of law enforcement agencies. To help combat poaching, the Protection Assistant for Wildlife Security (PAWS) is a machine learning pipeline that has been developed as a data-driven approach to identify areas at high risk of poaching throughout protected areas and compute optimal patrol routes. In this paper, we take an end-to-end approach to the data-to-deployment pipeline for anti-poaching. In doing so, we address challenges including extreme class imbalance (up to 1:200), bias, and uncertainty in wildlife poaching data to enhance PAWS, and we apply our methodology to three national parks with diverse characteristics. (i) We use Gaussian processes to quantify predictive uncertainty, which we exploit to improve robustness of our prescribed patrols and increase detection of snares by an average of 30%. We evaluate our approach on real-world historical poaching data from Murchison Falls and Queen Elizabeth National Parks in Uganda and, for the first time, Srepok Wildlife Sanctuary in Cambodia. (ii) We present the results of large-scale field tests conducted in Murchison Falls and Srepok Wildlife Sanctuary which confirm that the predictive power of PAWS extends promisingly to multiple parks. This paper is part of an effort to expand PAWS to 800 parks around the world through integration with SMART conservation software.

stat.AP↗

MIPaaL: Mixed Integer Program as a Layer

Machine learning components commonly appear in larger decision-making pipelines; however, the model training process typically focuses only on a loss that measures accuracy between predicted values and ground truth values. Decision-focused learning explicitly integrates the downstream decision problem when training the predictive model, in order to optimize the quality of decisions induced by the predictions. It has been successfully applied to several limited combinatorial problem classes, such as those that can be expressed as linear programs (LP), and submodular optimization. However, these previous applications have uniformly focused on problems from specific classes with simple constraints. Here, we enable decision-focused learning for the broad class of problems that can be encoded as a Mixed Integer Linear Program (MIP), hence supporting arbitrary linear constraints over discrete and continuous variables. We show how to differentiate through a MIP by employing a cutting planes solution approach, which is an exact algorithm that iteratively adds constraints to a continuous relaxation of the problem until an integral solution is found. We evaluate our new end-to-end approach on several real world domains and show that it outperforms the standard two phase approaches that treat prediction and prescription separately, as well as a baseline approach of simply applying decision-focused learning to the LP relaxation of the MIP.

cs.LG↗

Learning to Prescribe Interventions for Tuberculosis Patients Using Digital Adherence Data

Digital Adherence Technologies (DATs) are an increasingly popular method for verifying patient adherence to many medications. We analyze data from one city served by 99DOTS, a phone-call-based DAT deployed for Tuberculosis (TB) treatment in India where nearly 3 million people are afflicted with the disease each year. The data contains nearly 17,000 patients and 2.1M dose records. We lay the groundwork for learning from this real-world data, including a method for avoiding the effects of unobserved interventions in training data used for machine learning. We then construct a deep learning model, demonstrate its interpretability, and show how it can be adapted and trained in different clinical scenarios to better target and improve patient care. In the real-time risk prediction setting our model could be used to proactively intervene with 21% more patients and before 76% more missed doses than current heuristic baselines. For outcome prediction, our model performs 40% better than baseline methods, allowing cities to target more resources to clinics with a heavier burden of patients at risk of failure. Finally, we present a case study demonstrating how our model can be trained in an end-to-end decision focused learning setting to achieve 15% better solution quality in an example decision problem faced by health workers.

cs.LG↗

Group-Fairness in Influence Maximization

Influence maximization is a widely used model for information dissemination in social networks. Recent work has employed such interventions across a wide range of social problems, spanning public health, substance abuse, and international development (to name a few examples). A critical but understudied question is whether the benefits of such interventions are fairly distributed across different groups in the population; e.g., avoiding discrimination with respect to sensitive attributes such as race or gender. Drawing on legal and game-theoretic concepts, we introduce formal definitions of fairness in influence maximization. We provide an algorithmic framework to find solutions which satisfy fairness constraints, and in the process improve the state of the art for general multi-objective submodular maximization problems. Experimental results on real data from an HIV prevention intervention for homeless youth show that standard influence maximization techniques oftentimes neglect smaller groups which contribute less to overall utility, resulting in a disparity which our proposed algorithms substantially reduce.

cs.GT↗

Who and When to Screen: Multi-Round Active Screening for Recurrent Infectious Diseases Under Uncertainty

Controlling recurrent infectious diseases is a vital yet complicated problem. In this paper, we propose a novel active screening model (ACTS) and algorithms to facilitate active screening for recurrent diseases (no permanent immunity) under infection uncertainty. Our contributions are: (1) A new approach to modeling multi-round network-based screening/contact tracing under uncertainty, which is a common real-life practice in a variety of diseases; (2) Two novel algorithms, Full- and Fast-REMEDY. Full-REMEDY considers the effect of future actions and finds a policy that provides high solution quality, where Fast-REMEDY scales linearly in the size of the network; (3) We evaluate Full- and Fast-REMEDY on several real-world datasets which emulate human contact and find that they control diseases better than the baselines. To the best of our knowledge, this is the first work on multi-round active screening with uncertainty for diseases with no permanent immunity.

q-bio.QM↗

Social Network Based Substance Abuse Prevention via Network Modification (A Preliminary Study)

Substance use and abuse is a significant public health problem in the United States. Group-based intervention programs offer a promising means of preventing and reducing substance abuse. While effective, unfortunately, inappropriate intervention groups can result in an increase in deviant behaviors among participants, a process known as deviancy training. This paper investigates the problem of optimizing the social influence related to the deviant behavior via careful construction of the intervention groups. We propose a Mixed Integer Optimization formulation that decides on the intervention groups, captures the impact of the groups on the structure of the social network, and models the impact of these changes on behavior propagation. In addition, we propose a scalable hybrid meta-heuristic algorithm that combines Mixed Integer Programming and Large Neighborhood Search to find near-optimal network partitions. Our algorithm is packaged in the form of GUIDE, an AI-based decision aid that recommends intervention groups. Being the first quantitative decision aid of this kind, GUIDE is able to assist practitioners, in particular social workers, in three key areas: (a) GUIDE proposes near-optimal solutions that are shown, via extensive simulations, to significantly improve over the traditional qualitative practices for forming intervention groups; (b) GUIDE is able to identify circumstances when an intervention will lead to deviancy training, thus saving time, money, and effort; (c) GUIDE can evaluate current strategies of group formation and discard strategies that will lead to deviancy training. In developing GUIDE, we are primarily interested in substance use interventions among homeless youth as a high risk and vulnerable population. GUIDE is developed in collaboration with Urban Peak, a homeless-youth serving organization in Denver, CO, and is under preparation for deployment.

cs.SI↗