Miroslav Hekrdla | Searcharxiv

arXiv2026

High-resolution single-molecule mass measurement of megadalton assemblies in solution

Resolving heterogeneity in megadalton assemblies requires precise single-molecule mass measurements in solution. Mass photometry infers mass from individual molecular surface-landing events, and event-to-event measurement variability limits precision. Nanofluidic scattering microscopy overcomes this limitation by continuously tracking molecules in motion, enabling repeated sampling and temporal averaging of these fluctuations. Benchmarking with 4.5 MDa DNA origami demonstrates up to a fourfold improved resolution, approaching the performance of ensemble-averaged native mass spectrometry.

physics.optics↗

arXiv2015

Ordered Tomlinson-Harashima Precoding in G.fast Downstream

G.fast is an upcoming next generation DSL standard envisioned to use bandwidth up to 212 MHz. Far-end crosstalk (FEXT) at these frequencies greatly overcomes direct links. Its cancellation based on non-linear Tomlinson-Harashima Precoding (THP) proved to show significant advantage over standard linear precoding. This paper proposes a novel THP structure in which ordering of successive interference pre-cancellation can be optimized for downstream with non-cooperating receivers. The optimized scheme is compared to existing THP structure denoted as equal-rate THP which is widely adopted in wireless downlink. Structure and performance of both methods differ significantly favoring the proposed scheme. The ordering that maximizes the minimum rate (max-min fairness) for each tone of the discrete multi-tone modulation is the familiar V-BLAST ordering. However, V-BLAST does not lead to the global maximum when applied independently on each tone. The proposed novel Dynamic Ordering (DO) strategy takes into account asymmetric channel statistics to yield the highest minimum aggregated rate.

cs.IT↗