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Neo Christopher Chung

Publications and source records attributed to Neo Christopher Chung.

23 records · Page 2Linked to original sources

Human in the Loop for Machine Creativity

Artificial intelligence (AI) is increasingly utilized in synthesizing visuals, texts, and audio. These AI-based works, often derived from neural networks, are entering the mainstream market, as digital paintings, songs, books, and others. We conceptualize both existing and future human-in-the-loop (HITL) approaches for creative applications and to develop more expressive, nuanced, and multimodal models. Particularly, how can our expertise as curators and collaborators be encoded in AI models in an interactive manner? We examine and speculate on long term implications for models, interfaces, and machine creativity. Our selection, creation, and interpretation of AI art inherently contain our emotional responses, cultures, and contexts. Therefore, the proposed HITL may help algorithms to learn creative processes that are much harder to codify or quantify. We envision multimodal HITL processes, where texts, visuals, sounds, and other information are coupled together, with automated analysis of humans and environments. Overall, these HITL approaches will increase interaction between human and AI, and thus help the future AI systems to better understand our own creative and emotional processes.

cs.HC↗

Input Bias in Rectified Gradients and Modified Saliency Maps

Interpretation and improvement of deep neural networks relies on better understanding of their underlying mechanisms. In particular, gradients of classes or concepts with respect to the input features (e.g., pixels in images) are often used as importance scores or estimators, which are visualized in saliency maps. Thus, a family of saliency methods provide an intuitive way to identify input features with substantial influences on classifications or latent concepts. Several modifications to conventional saliency maps, such as Rectified Gradients and Layer-wise Relevance Propagation (LRP), have been introduced to allegedly denoise and improve interpretability. While visually coherent in certain cases, Rectified Gradients and other modified saliency maps introduce a strong input bias (e.g., brightness in the RGB space) because of inappropriate uses of the input features. We demonstrate that dark areas of an input image are not highlighted by a saliency map using Rectified Gradients, even if it is relevant for the class or concept. Even in the scaled images, the input bias exists around an artificial point in color spectrum. Our modification, which simply eliminates multiplication with input features, removes this bias. This showcases how a visual criteria may not align with true explainability of deep learning models.

cs.CV↗

Concept Saliency Maps to Visualize Relevant Features in Deep Generative Models

Evaluating, explaining, and visualizing high-level concepts in generative models, such as variational autoencoders (VAEs), is challenging in part due to a lack of known prediction classes that are required to generate saliency maps in supervised learning. While saliency maps may help identify relevant features (e.g., pixels) in the input for classification tasks of deep neural networks, similar frameworks are understudied in unsupervised learning. Therefore, we introduce a new method of obtaining saliency maps for latent representations of known or novel high-level concepts, often called concept vectors in generative models. Concept scores, analogous to class scores in classification tasks, are defined as dot products between concept vectors and encoded input data, which can be readily used to compute the gradients. The resulting concept saliency maps are shown to highlight input features deemed important for high-level concepts. Our method is applied to the VAE's latent space of CelebA dataset in which known attributes such as "smiles" and "hats" are used to elucidate relevant facial features. Furthermore, our application to spatial transcriptomic (ST) data of a mouse olfactory bulb demonstrates the potential of latent representations of morphological layers and molecular features in advancing our understanding of complex biological systems. By extending the popular method of saliency maps to generative models, the proposed concept saliency maps help improve interpretability of latent variable models in deep learning. Codes to reproduce and to implement concept saliency maps: https://github.com/lenbrocki/concept-saliency-maps

cs.LG↗

Jaccard/Tanimoto similarity test and estimation methods

Binary data are used in a broad area of biological sciences. Using binary presence-absence data, we can evaluate species co-occurrences that help elucidate relationships among organisms and environments. To summarize similarity between occurrences of species, we routinely use the Jaccard/Tanimoto coefficient, which is the ratio of their intersection to their union. It is natural, then, to identify statistically significant Jaccard/Tanimoto coefficients, which suggest non-random co-occurrences of species. However, statistical hypothesis testing using this similarity coefficient has been seldom used or studied. We introduce a hypothesis test for similarity for biological presence-absence data, using the Jaccard/Tanimoto coefficient. Several key improvements are presented including unbiased estimation of expectation and centered Jaccard/Tanimoto coefficients, that account for occurrence probabilities. We derived the exact and asymptotic solutions and developed the bootstrap and measurement concentration algorithms to compute statistical significance of binary similarity. Comprehensive simulation studies demonstrate that our proposed methods produce accurate p-values and false discovery rates. The proposed estimation methods are orders of magnitude faster than the exact solution. The proposed methods are implemented in an open source R package called jaccard (https://cran.r-project.org/package=jaccard). We introduce a suite of statistical methods for the Jaccard/Tanimoto similarity coefficient, that enable straightforward incorporation of probabilistic measures in analysis for species co-occurrences. Due to their generality, the proposed methods and implementations are applicable to a wide range of binary data arising from genomics, biochemistry, and other areas of science.

stat.ME↗

Statistical significance of variables driving systematic variation

There are a number of well-established methods such as principal components analysis (PCA) for automatically capturing systematic variation due to latent variables in large-scale genomic data. PCA and related methods may directly provide a quantitative characterization of a complex biological variable that is otherwise difficult to precisely define or model. An unsolved problem in this context is how to systematically identify the genomic variables that are drivers of systematic variation captured by PCA. Principal components (and other estimates of systematic variation) are directly constructed from the genomic variables themselves, making measures of statistical significance artificially inflated when using conventional methods due to over-fitting. We introduce a new approach called the jackstraw that allows one to accurately identify genomic variables that are statistically significantly associated with any subset or linear combination of principal components (PCs). The proposed method can greatly simplify complex significance testing problems encountered in genomics and can be utilized to identify the genomic variables significantly associated with latent variables. Using simulation, we demonstrate that our method attains accurate measures of statistical significance over a range of relevant scenarios. We consider yeast cell-cycle gene expression data, and show that the proposed method can be used to straightforwardly identify statistically significant genes that are cell-cycle regulated. We also analyze gene expression data from post-trauma patients, allowing the gene expression data to provide a molecularly-driven phenotype. We find a greater enrichment for inflammatory-related gene sets compared to using a clinically defined phenotype. The proposed method provides a useful bridge between large-scale quantifications of systematic variation and gene-level significance analyses.

stat.ME↗