arXiv subjects

Nima Hejazi

Publications and source records attributed to Nima Hejazi.

2 recordsLinked to original sources

arXiv2026

Evaluating the effects of policy interventions subject to early adoption: A case study of prescription drug monitoring programs and opioid dispensing

Policies that require organizations to use new systems, such as prescription drug monitoring programs (PDMPs), are often implemented in phases, with an initial period of voluntary access followed by mandated compliance. This allows the policy intervention to be adopted before compliance is required (early adoption), causing outcomes to change before the mandate takes effect. When early adoption is present, the no-anticipation assumption underlying synthetic control methods (SCM) is violated, leading to biased policy effect estimates. We formalize early adoption in a potential outcomes framework for staggered policy implementation and decompose the total policy effect into early adoption and mandate components. We then propose a two-stage, early adoption-aware SCM procedure that first estimates early adoption effects using an interactive fixed effects model fit to pre-mandate data and then residualizes outcomes before applying SCM variants to estimate mandate and total policy effects. Simulations, including settings with correlation between early adoption and latent factors, show reduced bias and improved uncertainty quantification relative to conventional SCM estimators. We apply the framework to state-level PDMP policies and per-capita opioid dispensing. After accounting for early adoption, estimates suggest reductions in opioid dispensing following PDMP availability and mandates; however, the estimates are imprecise and not statistically significant.

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arXiv2019

Causal mediation analysis for stochastic interventions

Mediation analysis in causal inference has traditionally focused on binary exposures and deterministic interventions, and a decomposition of the average treatment effect in terms of direct and indirect effects. In this paper we present an analogous decomposition of the \textit{population intervention effect}, defined through stochastic interventions on the exposure. Population intervention effects provide a generalized framework in which a variety of interesting causal contrasts can be defined, including effects for continuous and categorical exposures. We show that identification of direct and indirect effects for the population intervention effect requires weaker assumptions than its average treatment effect counterpart, under the assumption of no mediator-outcome confounders affected by exposure. In particular, identification of direct effects is guaranteed in experiments that randomize the exposure and the mediator. We discuss various estimators of the direct and indirect effects, including substitution, re-weighted, and efficient estimators based on flexible regression techniques, allowing for multivariate mediators. Our efficient estimator is asymptotically linear under a condition requiring $n^{1/4}$-consistency of certain regression functions. We perform a simulation study in which we assess the finite-sample properties of our proposed estimators. We present the results of an illustrative study where we assess the effect of participation in a sports team on BMI among children, using mediators such as exercise habits, daily consumption of snacks, and overweight status.

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