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Pascal Frossard

Publications and source records attributed to Pascal Frossard.

At least 19 recordsLinked to original sources

RePercENT: Scaling Disentangled Representation Learning Beyond Two Modalities

To leverage the full potential of multimodal data, we need representations that go beyond the state-of-the-art alignment and fusion approaches and exploit all cross-modal interactions without sacrificing modality-specific information. Learning disentangled representations is a principled way to identify the underlying shared and unique factors that are hidden in observational data. However, while multimodal disentanglement is a compelling paradigm, existing methods are largely confined to the two-modality regime due to its inherent scalability bottleneck. To address this, we propose RePercENT, a self-supervised framework designed to surpass these limitations and unlocks scalable pairwise disentanglement beyond two modalities. Through a multimodal `plug-and-play' architecture, our approach operates directly on pre-extracted embeddings, eliminating the need for extensive joint pre-training while making no assumptions regarding the underlying modalities or foundation model backbones. Moreover, we introduce a joint optimization objective for simultaneously deriving the shared and unique components, and provide formal theoretical guarantees that characterize the optimality of our solution. Spanning modalities from images and videos to clinical reports and omics, and tasks from sentiment analysis to tumor classification, RePercENT successfully recovers disentangled components while maintaining competitive performance and significantly reducing computational complexity.

cs.LG↗

Library of Layers (LoL): Adaptively Ordering Transformer Layers at Runtime

Computer programmers chain together the same reusable computational primitives, for example, conditional statements or loops, but in different orders to implement different algorithms. In contrast, existing language model architectures always execute their layers in the same order. We introduce Library of Layers (LoL), an architecture that dynamically orders its layers during inference to solve the problem at hand. LoL has a single hyperparameter, the size of its global library of transformer blocks, that allows it to transition seamlessly between parameter reuse and sparsity, generalizing the parameter-efficiency and FLOPs-efficiency tradeoffs of dense, depth-recurrent, and mixture of experts architectures in one unified family. We show that LoL achieves competitive performance with all three above baselines when pretrained on text data. On synthetic sudoku and maze data, we observe that the model employs distinct layer orderings to implement different solution strategies, and we can intervene on routing to force a model to apply a specific solution strategy to a problem instance. In a multilingual natural language setting, we find that LoL chooses different layer order patterns based on language and script. Similarly, we train LoL on safety data and fit probes to its router outputs, finding that these probes distinguish safe from unsafe text with high AUROC. LoL provides a path toward a future in which models dynamically compose their own computational graph, enabling more efficient and controllable reasoning.

cs.LG↗

PolarFlow: Spectral Geometric Flow Matching for Directed Graph Generation via Polar Decomposition

Directed graphs model asymmetric relationships in biology, transportation, social networks, and electronic design automation. Recent discrete diffusion and flow-matching methods generate directed graphs effectively, but their edge-wise categorical formulations require dense predictions over all ordered node pairs and repeated categorical updates during generation. This motivates a fundamental question: can comparable generative quality be achieved through a more computationally efficient formulation that better exploits the structure of directed adjacency matrices? Existing benchmarks also cover limited network structures, restricting comprehensive evaluation. We introduce PolarFlow, a continuous geometric flow-matching framework based on polar decomposition and truncated spectral coordinates. Its representation comprises four coupled components: a Stiefel frame and rotation angles encoding the orthogonal factor, and a second Stiefel frame and nonnegative eigenvalues characterizing the positive-semidefinite factor. PolarFlow learns a joint velocity field along geometry-aware conditional paths on this product space, reconstructs a continuous adjacency-score matrix, and discretizes it into a binary directed graph. By replacing discrete edge-wise generation with joint continuous transport, PolarFlow improves computational efficiency while retaining global adjacency structure. To broaden evaluation, we introduce complementary Circuit and Twitter benchmarks spanning engineered functional and naturally evolved social networks. Across synthetic and real-world datasets, PolarFlow achieves generative quality comparable to competitive discrete methods while substantially reducing training and sampling time.

eess.SP↗

Loopholing All the Way: Language Modeling with pure Self-Conditioning

Recent Diffusion Language Models (DLMs) use Self-Conditioning (SC), or Loopholing, to improve their performance. While SC is traditionally seen as an auxiliary heuristic, its empirical success raises the question: can a continuous generative model be based purely on Self-Conditioning? We answer affirmatively with LAW (``Loopholing All the Way''), which propagates the Expected Embedding under the denoiser's prediction across steps, decoding the tokens once, at the end. On Sudoku, LAW outperforms previous Discrete and Continuous Diffusion Models, including Loopholing Discrete Diffusion. On Maze, LAW is the most accurate from 2 to 64 NFE. After training on TinyGSM and sampling at temperature 1 with 1024 NFE, LAW solves 42.2% of GSM8K problems against 34.5% for uniform Loopholing Discrete Diffusion. Additionally, fine-tuning a pre-trained Uniform Diffusion Model (Duo) with LAW increases its accuracy from 17.2% to 48.1%. Finally, on OpenWebText, LAW pushes the Pareto frontier and approaches Autoregressive Models (ARMs) with 64 NFE. Find our code at https://github.com/ilievanadezhda/law.

cs.LG↗

PriFT: Guiding Supervised Fine-Tuning with Pretrained Priors

Supervised fine-tuning (SFT) is an efficient approach for downstream task adaptation and often serves as the initialization stage for reinforcement learning (RL), but it can show weaker generalization than RL. A key limitation is its off-policy objective: SFT fits fixed demonstrations token by token, including targets poorly aligned with the model's pretrained distribution, which can lead to overfitting. A recent line of work addresses this issue by assigning larger training weights to tokens better aligned with the current model's predictive distribution, with the intuition that fitting these tokens are less distortive to the model's knowledge and representations. However, computing the token weights from the model that is currently fine-tuned entangles token weights with the optimization trajectory, inducing a self-reinforcing loop which concentrates the supervision signal to a narrow set of initially preferred tokens. To address this, we propose PriFT (Prior-support guided Fine-Tuning), which derives token weights from a frozen pretrained reference to obtain a stable reweighting signal unaffected by fine-tuning. This signal estimates prior support: the extent to which each target token is supported by the pretrained distribution. By reweighting tokens according to their prior support, PriFT limits excessive adaptation to targets requiring substantial deviation from the pretrained distribution and improves SFT generalization. We introduce two instantiations: PriFT-prob uses pretrained target-token probability, while PriFT-mass selects tokens by cumulative probability mass under the pretrained distribution. Across mathematical reasoning, code generation, and medical QA, PriFT achieves state-of-the-art results among SFT baselines, while also providing a stronger initialization for subsequent RL.

cs.CL↗

Efficient Edge-aware Attention Network for Graph Generation

Graph generative models commonly use graph-specific Transformer architectures to jointly update node and edge features. However, these architectures do not directly benefit from recent hardware-aware attention implementations, limiting their scalability. The adaptation is, however, non-trivial: edge and graph-level features must be injected into pairwise attention scores, graph masks must be respected, and dynamic edge updates remain a major source of quadratic memory usage. We propose an edge-aware attention layer for graph generation that incorporates structural information through head-wise score modulation, while updating edge representations with a lightweight residual mechanism that retains attention-score dependent edge updates. This layer can be effectively implemented using PyTorch's FlexAttention. We achieve similar generation quality to our baseline while reducing peak GPU memory by around 65% and substantially improving training and sampling throughput. These results suggest that the proposed architecture is a practical step toward scalable graph foundation models.

cs.LG↗

spora: A Unified Multimodal Dataset and Platform for Spatial Proteomics

Spatial proteomics (SP) captures the molecular composition and spatial organization of tissues at single-cell resolution, opening a direct view of the cellular ecosystems that drive disease. Protein panels, acquisition platforms, and tissue contexts differ from one cohort to the next, and a coherent picture of tissue biology can only emerge from models trained to bridge this heterogeneity. Foundation models offer the natural path forward, but their training depends on large, harmonized corpora that span platforms, panels, and cohorts. No public resource currently approaches that scale; available data sit in small, narrowly scoped releases with incompatible formats and conventions. We present $\texttt{spora}$, a large-scale multimodal SP dataset of 13,546 standardized multiplex images from 5,477 patients across 35 cohorts and five major SP technologies. Curated with biomedical experts, $\texttt{spora}$ provides model training-ready formats together with cell and tissue segmentations, structured clinical metadata, and, where available, paired H&E enabling the training of virtual staining models. It is complemented by $\texttt{spora [io]}$, a unified interface for tiling, sampling, and standardization across all cohorts and modalities, and $\texttt{spora [bench]}$, a benchmark suite spanning cell phenotyping, diagnostic and therapeutic prediction as well as virtual staining tasks across twelve cohorts that places current SP foundation models on common ground against task specific baselines.

cs.CV↗

PING: physics informed graph neural network for advection-diffusion processes with applications to solar power forecasting

Advection-diffusion plays an essential role in transport phenomena such as atmospheric and cloud dynamics. Improved forecasting of cloud motion, in turn, enhances solar power production forecasts and facilitates the integration of additional photovoltaic (PV) sources into the power grid. However, both classical numerical models and emerging deep learning approaches face challenges when applied to spatially irregular sensor networks such as those formed by weather stations. In this work, we adopt a graph signal processing perspective and model advection-diffusion particles as signals on a graph to capture the dynamics of these processes. We introduce a Physics-Informed Graph Neural Network (PING) for forecasting future advection-diffusion particle concentrations on irregular grids. The model incorporates a discretized advection-diffusion equation as a soft constraint in the loss function to guide learning toward physically consistent solutions. This model is on par with state of the art models on synthetic and real transport phenomena datasets, including sea surface temperature and cloud index datasets. Furthermore, the PING model is successfully coupled with models for forecasting PV power production. This hybrid approach leverages data fusion from ground-based sensors at PV stations and satellite images with cloud concentration to improve the accuracy of intra-day PV power production.

cs.LG↗

Deep End-to-End Survival Analysis with Temporal Consistency

In this study, we present a novel Survival Analysis algorithm designed to efficiently handle large-scale longitudinal data. Our approach draws inspiration from Reinforcement Learning principles, particularly the Deep Q-Network paradigm, extending Temporal Learning concepts to Survival Regression. A central argument in our method relies on temporal consistency, a recursive consistency condition between survival predictions made at consecutive states. Our framework introduces a delayed target network that decouples the generation of temporally consistent training targets from model updates, providing a more stable training signal while enabling mini-batch optimization and end-to-end training. Additionally, it supports arbitrarily complex architectures, enabling the modeling of intricate temporal dependencies. Through numerous experiments we provide empirical evidence demonstrating our framework's ability to exploit temporal consistency across datasets of varying sizes. Moreover, our algorithm outperforms benchmarks on datasets with long sequences, demonstrating its ability to capture long-term patterns. Finally, ablation studies show that the degree of target delay has a substantial effect on predictive performance and training variability. Across two distinct survival model families, delayed target updates consistently improve over the same-timescale baseline.

cs.LG↗

Enhancing Diffusion Language Models with Autoregressive Post-Training Weights

Diffusion language models (dLLMs) have emerged as a promising alternative to autoregressive (AR) language models, offering flexible token-update orders and parallel decoding. Recent dLLMs are often initialized from pretrained AR models before diffusion conversion in order to inherit their learned representations. After the conversion, however, they typically ignore the extensive post-training ecosystem of their AR ancestors. In this work, we show that these existing AR post-training weight updates can instead be effectively recycled to enhance diffusion models. Despite the changes by AR-to-diffusion conversion, directly adding an AR post-training weight update to a diffusion base model remains effective, bringing its performance close to that achieved by direct diffusion post-training. Notably, AR and diffusion post-training updates are nearly orthogonal in weight space, yet induce substantially more aligned representation changes in the diffusion model. Their distinct updates are also complementary: composing their weights can retain gains from both regimes and further improve the post-trained diffusion model. Based on these findings, we propose A2D, a simple training-free framework for enhancing diffusion models with existing AR post-training resources. A2D can transfer capabilities from AR post-trained models to diffusion base models, and further improve already post-trained diffusion models by composing AR and diffusion post-training updates. Across various dLLMs, including Dream, DreamReasoner, DiffuCoder, Dream-Coder, Nemotron-Labs-Diffusion, and DiffusionGemma, A2D reliably improves instruction following, mathematical reasoning, and coding with both supervised fine-tuning and reinforcement learning updates, without additional training, or inference-time computation.

cs.LG↗

Uncertainty Estimation in Pathology Foundation Models via Deep Mutual Learning

Pathology foundation models (PFMs) offer generalizable representations for whole-slide image (WSI) analysis, yet their clinical adoption remains limited. Specifically, their predictions lack reliable confidence estimates, and no single PFM is universally best across tasks, which severely undermines trust in medical settings. To overcome this, we propose DICE, a plug-and-play framework that ensembles $K$ frozen PFMs and estimates uncertainty based on their consensus. We align the ensemble members via deep mutual learning and theoretically show that this objective controls an upper bound on epistemic uncertainty. Additionally, we demonstrate that the ensemble localizes abnormalities at the patch level without any explicit supervision. We evaluate DICE on three challenging WSI benchmarks. Notably, our framework provides reliable uncertainty estimates that accurately flag failure-prone cases under in- and out-of-distribution settings, while matching or outperforming SOTA baselines in classification, calibration, and localization. Overall, DICE takes a crucial step toward translating PFMs into uncertainty-aware decision-support systems.

cs.CV↗

Augmenting Large Audio Language Models with Low-Level Acoustic Features for Dysarthric Speech Detection

Automatic dysarthric speech detection approaches can support traditional clinical diagnosis, which relies on costly and time-consuming evaluation by a speech and language pathologist. Existing automatic approaches predominantly rely on deep learning (DL). More recently, Large Audio Language Models (LALMs) have emerged as a promising alternative given their strong performance across various tasks, but their application to dysarthric speech detection has not yet been established. We propose a framework that fine-tunes LALMs for dysarthric speech detection on speech recordings combined with textual information comprising low-level acoustic features and speaker demographics. Across two LALMs, our framework outperforms DL-based baselines, with Qwen2-Audio-Instruct achieving state-of-the-art performance. An ablation study shows that incorporating acoustic features and speaker demographics during fine-tuning improves LALM performance, while LALMs alone exhibit only chance-level zero-shot performance. These findings establish an effective approach for adapting LALMs to dysarthric speech detection.

eess.AS↗

Multiclass Speech Classification Under Noise Disparity

We investigate noise disparity in multi-class speech classification tasks and develop a strategy to prevent classifiers from exploiting class-dependent noise characteristics. Building on our previous work for binary classification, we introduce a multi-class cross-augmentation scheme that exposes each class to the noise characteristics of the other classes, thereby removing the association between individual noise conditions and class labels. We compare this training-based approach with speech enhancement (SE) as a preprocessing strategy, which aims to suppress noise-related cues directly from the input. Experiments on multi-class emotion recognition show that cross-augmentation effectively mitigates the effect of noise disparity across a range of signal-to-noise-ratios, while SE has a detrimental effect on model performance.

eess.AS↗

Recursive Scaling in Masked Diffusion Models

Masked diffusion models (MDMs) generate sequences by iteratively refining a partially masked state and committing tokens in parallel. We introduce recursion in MDMs and propose new Recursive Masked Diffusion Models (R-MDMs), which apply a shared denoising transformer $L$ times within each denoising step, adding recursive depth as an additional compute axis without increasing parameter count. Across structured generation tasks, recursive depth improves quality at fixed parameter budget, matches substantially larger non-recursive models at matched FLOPs, and can reduce the number of denoising steps needed to reach a target quality. We interpret these gains with a dependence--fidelity decomposition of parallel decoding error: recursion refines model marginals at a fixed masked state, whereas denoising steps change that state by committing tokens. Building on this analysis, we propose to treat decoding as a two-axis decision (how many loops to run and which tokens to commit) and show that entropy-guided adaptive rules improve the quality--compute frontier over fixed schedules, transferring across various tasks on Sudoku, Countdown, RNA, and executable math generation. Together, these results establish recursive depth as a practical, complementary test-time scaling mechanism for MDMs.

cs.LG↗

Frame the adversary: a structure-aware attack methodology

Frequency-based adversarial attacks have recently grown popular by exploiting spectral sensitivities shared across neural architectures. Unlike spatial perturbations, frequency-based attacks expose deeper vulnerabilities, making them especially valuable for robust evaluation of safety-critical and security-sensitive applications. Yet, existing approaches are typically not derived as solutions to an optimization problem that explicitly captures transform-domain structure. In this paper, we propose a methodology for crafting principled frequency-based adversarial attacks, via a dedicated optimization framework. A cornerstone of our method hinges on the introduction of a perturbation constraint set, tied to highly structured non-orthogonal transforms, well-known for their flexible, non-predefined frequency handling. We prove that the attacks emerge as weighted $\ell_2$-projections onto this set, yielding a general and controlled attack generation mechanism. By this, we provide a clear geometric attack characterization, ensuring alignment between the optimization objective and the perturbation constraint. We assess our framework on standardized datasets, for pretrained and adversarially robust models. Results highlight that our attacks, being solutions to an optimization problem, over a structured perturbation set, are highly effective, even across different, unseen architectures. Our methodology could serve as a theoretical baseline for designing and analyzing transformed-based attacks, targeting fundamental model vulnerabilities, instead of mere architecture-specific artifacts typically studied in the robustness literature.

cs.LG↗

Unsupervised Disentanglement Without Compromises : How Functional Orthogonality Enforces Identifiability

This paper explores unsupervised disentangled representation learning from a functional perspective. We define latent concepts as factors that influence observations through locally orthogonal directions, formalized as an orthogonality constraint on the Jacobian of the generative mapping. We prove that this condition yields identifiability of general nonlinear generative models, without requiring statistical independence or causal assumptions, provided the latent domain admits all combinations of factor values. Experiments with orthogonality-regularized normalizing flows empirically confirm the theory, demonstrate reliable recovery of ground-truth factors, and shed light on the success of VAEs. These findings challenge the prevailing impossibility claims for unsupervised disentanglement and provide a principled alternative foundation.

cs.LG↗

DBMol: Design of High-Affinity, Target-Specific Small Molecules through Structure Prediction Models

Designing small molecule ligands that bind with high affinity to specific protein pockets is a fundamental goal in drug discovery, as small molecules constitute a major fraction of approved therapeutics. Recent breakthroughs in structure prediction, such as AlphaFold-3 and Boltz-2, enable accurate biomolecular interaction prediction and show promise as foundation models for downstream tasks, including binding affinity prediction. We propose to leverage these models and introduce DBMol, a new structure predictor-guided framework for de novo small molecule design. DBMol formulates an alternating optimization and projection process. In the optimization stage, DBMol starts from an initial molecule and uses gradient-based optimization to improve pocket-specific interactions and predicted binding affinity using a structure prediction model. In the projection stage, a flow-matching model maps the optimized molecular graph to discrete and chemically valid molecules. Experiments show that DBMol effectively optimizes the Boltz-2 affinity proxy and generates molecules with strong predicted affinity and specificity under Boltz-2 evaluation. To reduce self-confirmation bias, we further evaluate generated molecules using held-out metrics, including AF3-based evaluation. DBMol substantially improves pocket coverage while maintaining molecular diversity over unconditional generation, and is competitive under held-out metrics despite the absence of reference-ligand supervision. These results support the promise of structure prediction models as effective optimization signals for de novo molecular design.

cs.LG↗

DiPhon: Diffusion on Graphons for Scalable Graph Generation

Diffusion models represent a leading paradigm for graph generation, with notable impact in domains such as molecular design. Yet, scaling these models to large graphs remains an open problem. We approach this question in the dense-graph setting through the lens of graphons, the size-agnostic limit objects of dense graph sequences, to study how structural graph statistics behave across node-size scales. This perspective leads to DiPhon, a diffusion framework for size-scalable graph generation. Specifically, we formulate a continuous diffusion process on the graphon space via a Jacobi stochastic differential equation (SDE), and propose DiPhon, a discretized graph-level process that mimics these dynamics on finite graphs. We further derive the corresponding reverse-time process, which requires access to the marginal score. For the Jacobi process, this score interestingly admits a tractable form, which we estimate from data via graph denoising and plug into the reverse process to generate graph samples. We prove that DiPhon matches exactly the first moment of the marginal distributions induced by the continuous graphon process, and approximates the second moment up to a closed-form discrepancy. Thus, DiPhon inherits key size-agnostic statistical properties of the graphon dynamics, providing a principled route toward scalable graph generation. Empirically, we demonstrate this scalability by training on small graphs and generating progressively larger graphs at inference time, without retraining, while preserving their core topological properties.

stat.ML↗