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Peilin Chen

Publications and source records attributed to Peilin Chen.

At least 19 recordsLinked to original sources

Lonic: Algorithm-Hardware Co-Design for Energy-Efficient Fully Local Online SNN Training with INT4 Precision

Spiking neural networks (SNNs) have recently attracted increasing attention as an energy-efficient learning paradigm. Existing works also propose temporally and fully local online SNN training algorithms to address memory and computation overhead. However, they do not consider whether the algorithmic advantages can be effectively translated into real-device efficiency. To address this challenge, we present Lonic, an algorithm-hardware co-design for energy-efficient and scalable fully local online supervised SNN learning. On the algorithm side, we implement an INT4 low-precision training algorithm for fully local online SNN learning while maintaining accuracy. On the hardware side, to leverage the benefits of the proposed algorithm, we introduce reconfigurable multiplier-free integer PE arrays, dual-optimization zero-gating strategy, temporal prefix-accelerated local learning dataflow, and low-precision weight movement to significantly improve training efficiency. Compared to Apple M4 and Nvidia V100 GPUs, Lonic achieves average energy efficiency improvements of 17.44x and 66.28x, respectively, along with speedups of 3.25x and 1.02x, respectively. Moreover, Lonic achieves 15.95x (14.64x) and 1.52x (7.28x) energy efficiency (area efficiency) over ASIC TPU-like and H2Learn accelerators, respectively. The code for Lonic is available at https://github.com/peilin-chen/Lonic.

cs.AR

Prior-Anchored Debiasing for Long-Tailed Multi-Organ Pathology Report Generation

Automated pathology report generation from Whole Slide Images (WSIs) has attracted increasing attention in digital pathology. However, existing methods are predominantly developed under single-organ settings, overlooking the multi-organ scenarios encountered in clinical practice, where organ types typically follow a long-tailed distribution. To address this gap, we identify two critical biases: (1) visual representation bias, where the encoder favors head-class patterns over tail-class discriminative features, and (2) textual decoding bias, where the decoder overfits to head-class narrative patterns, yielding diagnostically unreliable outputs for tail-class organs. To mitigate these two biases, we propose a novel Prior-anchored multi-Organ pathology report Generation framework (PriOrGen). Specifically, a Visual-Prototype Anchored Bottleneck module leverages the information bottleneck principle with learnable anchor representations to selectively retain diagnostically relevant visual information while filtering out head-biased redundancy. Secondly, a Meta-Report Anchored Bank module constructs an organ-specific meta-report anchored bank and retrieves organ-faithful textual priors to steer the decoder away from head-class narrative patterns. Extensive experiments on a multi-organ pathology dataset demonstrate that our method effectively mitigates long-tail biases and achieves superior report generation performance across both head and tail organ categories compared to state-of-the-art methods.

cs.CV

SpikON: A Dual-Parallel and Efficient Accelerator for Online Spiking Neural Networks Learning

Spiking neural networks (SNNs) have emerged as a promising paradigm for energy-efficient brain-inspired computing. However, existing online unsupervised SNN learning suffers from low training accuracy and poor scalability. Although current online supervised learning algorithms perform well on large-scale datasets and networks, the non-hardware-friendly operations hinder efficient edge deployment. In this work, we propose SpikON, the first algorithm-hardware co-design framework for efficient and scalable end-to-end online supervised SNN learning. We first propose the learnable threshold through time and scaled weight centralization through time techniques to address the inefficiency of traditional algorithms. Moreover, to reduce latency and energy consumption, we introduce the novel training dataflow and cascade computation reuse scheme for SNNs that allows concurrent forward-backward computation and temporal reuse across timesteps. We further design the dedicated SNN accelerator with a dual-parallel engine and customized SIMD-based SNN core for efficient end-to-end online learning. Experiments show that the SpikON algorithm achieves 32.2% and 35.0% reductions in training latency and energy consumption over the baseline, without sacrificing accuracy. Moreover, the SpikON co-design achieves 7.2x (11.5x) and 26.8x (15.8x) training throughput (energy efficiency) compared with the edge Apple M4 GPU and TPU-like accelerator, respectively. The code is available at https://github.com/peilin-chen/SpikON.

cs.AR

When Recovery Matters: The Blind Spot of Surrogate Privacy in MLLM Editing

Multimodal Large Language Models (MLLMs) enable flexible instruction-driven image editing, but privacy risks arise when user images expose diverse and user-specific private content. Canonical privacy protection strategies typically substitute sensitive regions with surrogate content before cloud editing. Yet, the resulting output is often an edited surrogate rather than the desired edited source image, neglecting the local recovery in both design and evaluation scope. To this end, we introduce SPPE (Surrogate-based Privacy-Preserving Editing), the first recovery-oriented benchmark covering 36 fine-grained privacy categories and 65 editing instructions. It defines two complementary tasks: 1) editability assessment, which estimates before cloud interaction whether a surrogate can induce an edit consistent with the original image; and 2) surrogate-to-source edit recovery, which evaluates whether the edited surrogate can be transferred back to the private source with the edit effect preserved. We address each task with a dedicated method: ERMA predicts surrogate editability through instruction-aware multimodal relation modeling, while \method performs cycle-consistent recovery by using the surrogate editing pair as visual edit evidence and the source image as a source-preserving anchor. Experiments on SPPE and InstructPix2Pix show consistent improvements on both tasks. For editability assessment, ERMA improves over the best-performing baselines by 13.9% in SRCC and 12.3% in PLCC. For surrogate-to-source edit recovery, C2E-S2SER outperforms SOER across all 8 source integrity and edit consistency metrics on SPPE.

cs.CV

Seeing Without Exposing: Adaptive Privacy Control for Open-World, Context-Hungry MLLMs

Multimodal large language models (MLLMs) have raised new privacy challenges. On the data side, user-provided inputs often include unpredictable sensitive information; while on the downstream task side, model reasoning depends on rich visual context that may itself be privacy-sensitive. Existing privacy protection methods, however, rely on predefined sensitive categories and fixed obfuscation strategies, struggling to tackle such challenges in MLLMs. To address this dilemma, we propose Anchored Privacy Drifting (APD), a training-free method that drifts privacy-sensitive elements toward semantically equivalent alternatives while anchoring contextual cues to the source image. To systematically evaluate this dual objective of privacy protection and contextual preservation, we introduce AdaptShield, a comprehensive benchmark covering 22 privacy categories, which combines conventional privacy metrics with MLLM-based assessments of contextual utility. Extensive experiments show that our method achieves balanced improvements in both privacy sanitization and content retention, with average gains of 10.4% on textual categories and 8.5% under MLLM-based evaluation across four MLLM series, i.e., Qwen2.5, Qwen3, InternVL3, and InternVL3.5.

cs.CV

RAISE: RAG Design as an Architecture Search Problem

Retrieval-augmented generation (RAG) systems expose numerous design choices spanning query rewriting, chunking, retrieval depth, reranking, and context compression. In practice, these choices are often configured through heuristics, hindering systematic evaluation and reproducibility across settings. We argue that this challenge is best formulated as RAG architecture search. To support controlled and reproducible study of this problem, we introduce the RAG Intelligence Search Engine (RAISE), a comprehensive framework and benchmark for RAG hyperparameter optimization, which evaluates optimization methods for RAG pipelines under standardized search spaces and budgets. RAISE implements 13 search algorithms and evaluates them across seven public text and multimodal datasets using three random seeds. Our experiments show that optimization performance is highly task-dependent: methods that perform strongly on one dataset may not generalize consistently across others, cautioning against interpreting aggregate rankings as evidence of universally superior strategies. RAISE provides a common experimental substrate for fair, reproducible, and systematic research on RAG hyperparameter optimization.

cs.AI

TIGER: Text-Informed Generalized Enzyme-Reaction Retrieval

Enzyme-reaction retrieval is a fundamental problem in computational biology, underpinning enzyme characterization, reaction mechanism elucidation, and the rational design of metabolic pathways and biocatalysts. As a bidirectional task, it entails both enzyme-to-reaction and reaction-to-enzyme mapping. However, existing approaches suffer from poor generalization across tasks and distributions, with performance highly sensitive to dataset splits and substantial asymmetry between retrieval directions. To address these challenges, we present TIGER, a Text-Informed Generalized Enzyme-Reaction Retrieval framework that leverages protein-to-text generation models to distill textual semantic knowledge from enzyme sequences, providing a generalized representation that bridges enzymes and biochemical reactions. To ensure the quality and reliability of textual semantics, we design a Dynamic Gating Network that adaptively fuses text-derived knowledge with sequence features, enabling more consistent and informative enzyme representations, while a Structure-Shared Feature Projector aligns enzyme and reaction representations within a unified latent space. Extensive experiments demonstrate that, under bidirectional retrieval supervision, TIGER significantly outperforms state-of-the-art baselines across diverse distributions and exhibits strong robustness and transferability across tasks.

cs.AI

Orion-RAG: Path-Aligned Hybrid Retrieval for Graphless Data

Retrieval-Augmented Generation (RAG) has proven effective for knowledge synthesis, yet it encounters significant challenges in practical scenarios where data is inherently discrete and fragmented. In most environments, information is distributed across isolated files like reports and logs that lack explicit links. Standard search engines process files independently, ignoring the connections between them. Furthermore, manually building Knowledge Graphs is impractical for such vast data. To bridge this gap, we present Orion-RAG. Our core insight is simple yet effective: we do not need heavy algorithms to organize this data. Instead, we use a low-complexity strategy to extract lightweight paths that naturally link related concepts. We demonstrate that this streamlined approach suffices to transform fragmented documents into semi-structured data, enabling the system to link information across different files effectively. Extensive experiments demonstrate that Orion-RAG consistently outperforms mainstream frameworks across diverse domains, supporting real-time updates and explicit Human-in-the-Loop verification with high cost-efficiency. Experiments on FinanceBench demonstrate superior precision with a 25.2% relative improvement over strong baselines.

cs.AI

MolMark: Safeguarding Molecular Structures through Learnable Atom-Level Watermarking

AI-driven molecular generation is reshaping drug discovery and materials design, yet the lack of protection mechanisms leaves AI-generated molecules vulnerable to unauthorized reuse and provenance ambiguity. Such limitation undermines both scientific reproducibility and intellectual property security. To address this challenge, we propose the first deep learning based watermarking framework for molecules (MolMark), which is exquisitely designed to embed high-fidelity digital signatures into molecules without compromising molecular functionalities. MolMark learns to modulate the chemically meaningful atom-level representations and enforce geometric robustness through SE(3)-invariant features, maintaining robustness under rotation, translation, and reflection. Additionally, MolMark integrates seamlessly with AI-based molecular generative models, enabling watermarking to be treated as a learned transformation with minimal interference to molecular structures. Experiments on benchmark datasets (QM9, GEOM-DRUG) and state-of-the-art molecular generative models (GeoBFN, GeoLDM) demonstrate that MolMark can embed 16-bit watermarks while retaining more than 90% of essential molecular properties, preserving downstream performance, and enabling >95% extraction accuracy under SE(3) transformations. MolMark establishes a principled pathway for unifying molecular generation with verifiable authorship, supporting trustworthy and accountable AI-driven molecular discovery.

cs.LG

When Privacy Meets Recovery: The Overlooked Half of Surrogate-Driven Privacy Preservation for MLLM Editing

Privacy leakage in Multimodal Large Language Models (MLLMs) has long been an intractable problem. Existing studies, though effectively obscure private information in MLLMs, often overlook the evaluation of the authenticity and recovery quality of user privacy. To this end, this work uniquely focuses on the critical challenge of how to restore surrogate-driven protected data in diverse MLLM scenarios. We first bridge this research gap by contributing the SPPE (Surrogate Privacy Protected Editable) dataset, which includes a wide range of privacy categories and user instructions to simulate real MLLM applications. This dataset offers protected surrogates alongside their various MLLM-edited versions, thus enabling the direct assessment of privacy recovery quality. By formulating privacy recovery as a guided generation task conditioned on complementary multimodal signals, we further introduce a unified approach that reliably reconstructs private content while preserving the fidelity of MLLM-generated edits. The experiments on both SPPE and InstructPix2Pix further show that our approach generalizes well across diverse visual content and editing tasks, achieving a strong balance between privacy protection and MLLM usability.

cs.CV

End-to-End Transformer Acceleration Through Processing-in-Memory Architectures

Transformers have become central to natural language processing and large language models, but their deployment at scale faces three major challenges. First, the attention mechanism requires massive matrix multiplications and frequent movement of intermediate results between memory and compute units, leading to high latency and energy costs. Second, in long-context inference, the key-value cache (KV cache) can grow unpredictably and even surpass the model's weight size, creating severe memory and bandwidth bottlenecks. Third, the quadratic complexity of attention with respect to sequence length amplifies both data movement and compute overhead, making large-scale inference inefficient. To address these issues, this work introduces processing-in-memory solutions that restructure attention and feed-forward computation to minimize off-chip data transfers, dynamically compress and prune the KV cache to manage memory growth, and reinterpret attention as an associative memory operation to reduce complexity and hardware footprint. Moreover, we evaluate our processing-in-memory design against state-of-the-art accelerators and general-purpose GPUs, demonstrating significant improvements in energy efficiency and latency. Together, these approaches address computation overhead, memory scalability, and attention complexity, further enabling efficient, end-to-end acceleration of Transformer models.

cs.AR

QoQ-Med: Building Multimodal Clinical Foundation Models with Domain-Aware GRPO Training

Clinical decision-making routinely demands reasoning over heterogeneous data, yet existing multimodal language models (MLLMs) remain largely vision-centric and fail to generalize across clinical specialties. To bridge this gap, we introduce QoQ-Med-7B/32B, the first open generalist clinical foundation model that jointly reasons across medical images, time-series signals, and text reports. QoQ-Med is trained with Domain-aware Relative Policy Optimization (DRPO), a novel reinforcement-learning objective that hierarchically scales normalized rewards according to domain rarity and modality difficulty, mitigating performance imbalance caused by skewed clinical data distributions. Trained on 2.61 million instruction tuning pairs spanning 9 clinical domains, we show that DRPO training boosts diagnostic performance by 43% in macro-F1 on average across all visual domains as compared to other critic-free training methods like GRPO. Furthermore, with QoQ-Med trained on intensive segmentation data, it is able to highlight salient regions related to the diagnosis, with an IoU 10x higher than open models while reaching the performance of OpenAI o4-mini. To foster reproducibility and downstream research, we release (i) the full model weights, (ii) the modular training pipeline, and (iii) all intermediate reasoning traces at https://github.com/DDVD233/QoQ_Med.

cs.LG

VQualA 2025 Challenge on Visual Quality Comparison for Large Multimodal Models: Methods and Results

This paper presents a summary of the VQualA 2025 Challenge on Visual Quality Comparison for Large Multimodal Models (LMMs), hosted as part of the ICCV 2025 Workshop on Visual Quality Assessment. The challenge aims to evaluate and enhance the ability of state-of-the-art LMMs to perform open-ended and detailed reasoning about visual quality differences across multiple images. To this end, the competition introduces a novel benchmark comprising thousands of coarse-to-fine grained visual quality comparison tasks, spanning single images, pairs, and multi-image groups. Each task requires models to provide accurate quality judgments. The competition emphasizes holistic evaluation protocols, including 2AFC-based binary preference and multi-choice questions (MCQs). Around 100 participants submitted entries, with five models demonstrating the emerging capabilities of instruction-tuned LMMs on quality assessment. This challenge marks a significant step toward open-domain visual quality reasoning and comparison and serves as a catalyst for future research on interpretable and human-aligned quality evaluation systems.

cs.CV

Freeze-in gravitational waves and dark matter in warm inflation

Recent study [1] has suggested that warm inflation may be realized with a minimal extension of the Standard Model by a single scalar inflaton field with an axion-like coupling to gluons. Motivated by this framework, we investigate the gravitational wave spectrum and graviton-portal dark matter production through the freeze-in process generated during warm inflation scenarios. We perform a comparative analysis for different dissipation terms, focusing on their distinct gravitational wave signatures in the high-frequency regime. Our findings reveal qualitative and quantitative differences in the spectral behavior, offering a preliminary pathway for exploring inflationary and dark matter models through high-frequency gravitational wave signals.

hep-ph

KEPLA: A Knowledge-Enhanced Deep Learning Framework for Accurate Protein-Ligand Binding Affinity Prediction

Accurate prediction of protein-ligand binding affinity is critical for drug discovery. While recent deep learning approaches have demonstrated promising results, they often rely solely on structural features of proteins and ligands, overlooking their valuable biochemical knowledge associated with binding affinity. To address this limitation, we propose KEPLA, a novel deep learning framework that explicitly integrates prior knowledge from Gene Ontology and ligand properties to enhance prediction performance. KEPLA takes protein sequences and ligand molecular graphs as input and optimizes two complementary objectives: (1) aligning global representations with knowledge graph relations to capture domain-specific biochemical insights, and (2) leveraging cross attention between local representations to construct fine-grained joint embeddings for prediction. Experiments on two benchmark datasets across both in-domain and cross-domain scenarios demonstrate that KEPLA consistently outperforms state-of-the-art baselines. Furthermore, interpretability analyses based on knowledge graph relations and cross attention maps provide valuable insights into the underlying predictive mechanisms.

cs.LG

Fine-Grained Motion Compression and Selective Temporal Fusion for Neural B-Frame Video Coding

With the remarkable progress in neural P-frame video coding, neural B-frame coding has recently emerged as a critical research direction. However, most existing neural B-frame codecs directly adopt P-frame coding tools without adequately addressing the unique challenges of B-frame compression, leading to suboptimal performance. To bridge this gap, we propose novel enhancements for motion compression and temporal fusion for neural B-frame coding. First, we design a fine-grained motion compression method. This method incorporates an interactive dual-branch motion auto-encoder with per-branch adaptive quantization steps, which enables fine-grained compression of bi-directional motion vectors while accommodating their asymmetric bitrate allocation and reconstruction quality requirements. Furthermore, this method involves an interactive motion entropy model that exploits correlations between bi-directional motion latent representations by interactively leveraging partitioned latent segments as directional priors. Second, we propose a selective temporal fusion method that predicts bi-directional fusion weights to achieve discriminative utilization of bi-directional multi-scale temporal contexts with varying qualities. Additionally, this method introduces a hyperprior-based implicit alignment mechanism for contextual entropy modeling. By treating the hyperprior as a surrogate for the contextual latent representation, this mechanism implicitly mitigates the misalignment in the fused bi-directional temporal priors. Extensive experiments demonstrate that our proposed codec achieves an average BD-rate reduction of approximately 10% compared to the state-of-the-art neural B-frame codec, DCVC-B, and delivers comparable or even superior compression performance to the H.266/VVC reference software under random-access configurations.

eess.IV

Titanus: Enabling KV Cache Pruning and Quantization On-the-Fly for LLM Acceleration

Large language models (LLMs) have gained great success in various domains. Existing systems cache Key and Value within the attention block to avoid redundant computations. However, the size of key-value cache (KV cache) is unpredictable and can even be tens of times larger than the weights in the long context length scenario. In this work, we propose Titanus, a software-hardware co-design to efficiently compress the KV cache on-the-fly. We first propose the cascade pruning-quantization (CPQ) method to reduce the KV cache movement. The hierarchical quantization extension strategy is introduced to tackle the non-independent per-channel quantization issue. To further reduce KV cache movement, we transfer only the non-zero KV cache between the accelerator and off-chip memory. Moreover, we customize a two-stage design space exploration framework for the CPQ method. A novel pipeline and parallelism dataflow is designed to reduce the first token generation time. Experiments show that Titanus achieves 159.9x (49.6x) and 34.8x (29.2x) energy efficiency (throughput) compared to Nvidia A100 GPU and FlightLLM respectively. The code for Titanus is available at https://github.com/peilin-chen/Titanus-for-LLM-acceleration.

cs.AR

RCNet: Deep Recurrent Collaborative Network for Multi-View Low-Light Image Enhancement

Scene observation from multiple perspectives would bring a more comprehensive visual experience. However, in the context of acquiring multiple views in the dark, the highly correlated views are seriously alienated, making it challenging to improve scene understanding with auxiliary views. Recent single image-based enhancement methods may not be able to provide consistently desirable restoration performance for all views due to the ignorance of potential feature correspondence among different views. To alleviate this issue, we make the first attempt to investigate multi-view low-light image enhancement. First, we construct a new dataset called Multi-View Low-light Triplets (MVLT), including 1,860 pairs of triple images with large illumination ranges and wide noise distribution. Each triplet is equipped with three different viewpoints towards the same scene. Second, we propose a deep multi-view enhancement framework based on the Recurrent Collaborative Network (RCNet). Specifically, in order to benefit from similar texture correspondence across different views, we design the recurrent feature enhancement, alignment and fusion (ReEAF) module, in which intra-view feature enhancement (Intra-view EN) followed by inter-view feature alignment and fusion (Inter-view AF) is performed to model the intra-view and inter-view feature propagation sequentially via multi-view collaboration. In addition, two different modules from enhancement to alignment (E2A) and from alignment to enhancement (A2E) are developed to enable the interactions between Intra-view EN and Inter-view AF, which explicitly utilize attentive feature weighting and sampling for enhancement and alignment, respectively. Experimental results demonstrate that our RCNet significantly outperforms other state-of-the-art methods. All of our dataset, code, and model will be available at https://github.com/hluo29/RCNet.

cs.CV