arXiv subjects

Rui Feng

Publications and source records attributed to Rui Feng.

At least 37 records · Page 2Linked to original sources

arXiv2025

FineMedLM-o1: Enhancing Medical Knowledge Reasoning Ability of LLM from Supervised Fine-Tuning to Test-Time Training

Recent advancements in large language models (LLMs) have shown promise in medical applications such as disease diagnosis and treatment planning. However, most existing medical LLMs struggle with the deep reasoning required for complex medical problems, such as differential diagnosis and medication recommendations. We propose FineMedLM-o1, which leverages high-quality medical synthetic data and long-form reasoning data for Supervised Fine-Tuning (SFT) and Direct Preference Optimization (DPO), enabling advanced dialogue and deep reasoning capabilities. Additionally, we introduce Test-Time Training (TTT) in the medical domain for the first time, facilitating domain adaptation and ensuring reliable, accurate reasoning. Experimental results demonstrate that FineMedLM-o1 achieves a 23% average performance improvement over prior models on key medical benchmarks. Furthermore, the introduction of TTT provides an additional 14% performance boost, highlighting its effectiveness in enhancing medical reasoning capabilities. To support this process, we also propose a novel method for synthesizing medical dialogue. Compared to other open-source datasets, our dataset stands out as superior in both quality and complexity. The project and data will be released on GitHub.

cs.CL↗

arXiv2025

Regression Analysis of Reciprocity in Directed Networks

Reciprocity--the tendency of individuals to form mutual ties--is a fundamental structural feature of many directed networks. Despite its ubiquity, reciprocity remains insufficiently integrated into statistical network models, particularly in relation to covariate information. In this paper, we introduce the $R^{2}$-Model, a novel and flexible framework that explicitly models reciprocity while incorporating covariate effects. Built upon a generalized $p_1$ model, our framework accommodates both network sparsity and node heterogeneity, offering the most comprehensive parametrization of reciprocity to date--capturing not only its baseline level but also how it systematically varies with observed covariates. To address the challenges posed by high dimensionality and nuisance parameters, we develop a conditional likelihood estimator that isolates and consistently estimates the reciprocity effects. We establish its theoretical guarantees, including consistency, asymptotic normality, and minimax optimality under broad sparsity regimes. Extensive simulations and real-world applications demonstrate the $R^{2}$-Model's flexibility, interpretability, and strong finite-sample performance, highlighting its practical utility for uncovering covariate-driven patterns of reciprocity in directed networks.

stat.ME↗

arXiv2025

Exploring Gender Bias in Alzheimer's Disease Detection: Insights from Mandarin and Greek Speech Perception

Gender bias has been widely observed in speech perception tasks, influenced by the fundamental voicing differences between genders. This study reveals a gender bias in the perception of Alzheimer's Disease (AD) speech. In a perception experiment involving 16 Chinese listeners evaluating both Chinese and Greek speech, we identified that male speech was more frequently identified as AD, with this bias being particularly pronounced in Chinese speech. Acoustic analysis showed that shimmer values in male speech were significantly associated with AD perception, while speech portion exhibited a significant negative correlation with AD identification. Although language did not have a significant impact on AD perception, our findings underscore the critical role of gender bias in AD speech perception. This work highlights the necessity of addressing gender bias when developing AD detection models and calls for further research to validate model performance across different linguistic contexts.

cs.CL↗

arXiv2025

Dual Semantic-Aware Network for Noise Suppressed Ultrasound Video Segmentation

Ultrasound imaging is a prevalent diagnostic tool known for its simplicity and non-invasiveness. However, its inherent characteristics often introduce substantial noise, posing considerable challenges for automated lesion or organ segmentation in ultrasound video sequences. To address these limitations, we propose the Dual Semantic-Aware Network (DSANet), a novel framework designed to enhance noise robustness in ultrasound video segmentation by fostering mutual semantic awareness between local and global features. Specifically, we introduce an Adjacent-Frame Semantic-Aware (AFSA) module, which constructs a channel-wise similarity matrix to guide feature fusion across adjacent frames, effectively mitigating the impact of random noise without relying on pixel-level relationships. Additionally, we propose a Local-and-Global Semantic-Aware (LGSA) module that reorganizes and fuses temporal unconditional local features, which capture spatial details independently at each frame, with conditional global features that incorporate temporal context from adjacent frames. This integration facilitates multi-level semantic representation, significantly improving the model's resilience to noise interference. Extensive evaluations on four benchmark datasets demonstrate that DSANet substantially outperforms state-of-the-art methods in segmentation accuracy. Moreover, since our model avoids pixel-level feature dependencies, it achieves significantly higher inference FPS than video-based methods, and even surpasses some image-based models. Code can be found in \href{https://github.com/ZhouL2001/DSANet}{DSANet}

cs.CV↗

arXiv2025

Advancing Lung Disease Diagnosis in 3D CT Scans

To enable more accurate diagnosis of lung disease in chest CT scans, we propose a straightforward yet effective model. Firstly, we analyze the characteristics of 3D CT scans and remove non-lung regions, which helps the model focus on lesion-related areas and reduces computational cost. We adopt ResNeSt50 as a strong feature extractor, and use a weighted cross-entropy loss to mitigate class imbalance, especially for the underrepresented squamous cell carcinoma category. Our model achieves a Macro F1 Score of 0.80 on the validation set of the Fair Disease Diagnosis Challenge, demonstrating its strong performance in distinguishing between different lung conditions.

eess.IV↗

arXiv2025

Multi-Source COVID-19 Detection via Variance Risk Extrapolation

We present our solution for the Multi-Source COVID-19 Detection Challenge, which aims to classify chest CT scans into COVID and Non-COVID categories across data collected from four distinct hospitals and medical centers. A major challenge in this task lies in the domain shift caused by variations in imaging protocols, scanners, and patient populations across institutions. To enhance the cross-domain generalization of our model, we incorporate Variance Risk Extrapolation (VREx) into the training process. VREx encourages the model to maintain consistent performance across multiple source domains by explicitly minimizing the variance of empirical risks across environments. This regularization strategy reduces overfitting to center-specific features and promotes learning of domain-invariant representations. We further apply Mixup data augmentation to improve generalization and robustness. Mixup interpolates both the inputs and labels of randomly selected pairs of training samples, encouraging the model to behave linearly between examples and enhancing its resilience to noise and limited data. Our method achieves an average macro F1 score of 0.96 across the four sources on the validation set, demonstrating strong generalization.

eess.IV↗

arXiv2025

Compact Amplified Laser Power Stabilization Using Robust Active Disturbance Rejection Control with Sensor Noise Decoupling

Laser power instability, encompassing random jitter and slow drift, severely limits the performance of optically pumped magnetometers (OPMs) in detecting ultra-weak magnetic fields, especially in large-scale OPM arrays for magnetoencephalography. Although a unified amplified laser (AL) architecture improves integration, fluctuations in the pump beam progressively degrade performance across all channels, exacerbated by environmental disturbances and system uncertainties. To address this challenge, this paper presents a compact AL power stabilization approach based on an innovative dual-loop active disturbance rejection control (DLADRC) strategy, while integrating a comprehensive quantitative stability analysis through novel exponential decay estimates for extended state observers (ESOs) and control error dynamics. As validated through physical experimental results, the proposed method significantly improves AL's long-term stability with sensor noise decoupling, achieving an over 85.7% reduction in 1-hour power instability and a tenfold decrease in Allan variance for correlation times 10^2 s--10^3 s, compared to standard ADRC. Crucially, the strategy demonstrates robust effectiveness across diverse operating scenarios, enabling AL-based OPM systems to achieve their full potential in high-sensitivity biomagnetic field detection.

eess.SY↗

arXiv2025

Physics-Informed Neural Network for Cross-Domain Predictive Control of Tapered Amplifier Thermal Stabilization

Thermally induced laser noise poses a critical limitation to the sensitivity of quantum sensor arrays employing ultra-stable amplified lasers, primarily stemming from nonlinear gain-temperature coupling effects in tapered amplifiers (TAs). To address this challenge, we present a robust intelligent control strategy that synergistically integrates an encoder-decoder physics-informed gated recurrent unit (PI-GRU) network with a model predictive control (MPC) framework. Our methodology incorporates physical soft constraints into the neural network architecture, yielding a predictive model with enhanced physical consistency that demonstrates robust extrapolation capabilities beyond the training data distribution. Leveraging the PI-GRU model's accurate multi-step predictive performance, we implement a hierarchical parallel MPC architecture capable of real-time thermal instability compensation. This hybrid approach achieves cross-domain consistent thermal stabilization in TAs under diverse laser power operations. Remarkably, while trained exclusively on low-power operational data, our system demonstrates exceptional generalization, improving prediction accuracy by 58.2% and temperature stability by 69.1% in previously unseen high-power operating regimes, as experimentally validated. The novel synchronization of physics-informed neural networks with advanced MPC frameworks presented in this work establishes a groundbreaking paradigm for addressing robustness challenges in cross-domain predictive control applications, overcoming conventional modeling limitations.

eess.SY↗

arXiv2025

Leveraging Cascaded Binary Classification and Multimodal Fusion for Dementia Detection through Spontaneous Speech

This paper presents our submission to the PROCESS Challenge 2025, focusing on spontaneous speech analysis for early dementia detection. For the three-class classification task (Healthy Control, Mild Cognitive Impairment, and Dementia), we propose a cascaded binary classification framework that fine-tunes pre-trained language models and incorporates pause encoding to better capture disfluencies. This design streamlines multi-class classification and addresses class imbalance by restructuring the decision process. For the Mini-Mental State Examination score regression task, we develop an enhanced multimodal fusion system that combines diverse acoustic and linguistic features. Separate regression models are trained on individual feature sets, with ensemble learning applied through score averaging. Experimental results on the test set outperform the baselines provided by the organizers in both tasks, demonstrating the robustness and effectiveness of our approach.

eess.AS↗

arXiv2025

Decoding Speaker-Normalized Pitch from EEG for Mandarin Perception

The same speech content produced by different speakers exhibits significant differences in pitch contour, yet listeners' semantic perception remains unaffected. This phenomenon may stem from the brain's perception of pitch contours being independent of individual speakers' pitch ranges. In this work, we recorded electroencephalogram (EEG) while participants listened to Mandarin monosyllables with varying tones, phonemes, and speakers. The CE-ViViT model is proposed to decode raw or speaker-normalized pitch contours directly from EEG. Experimental results demonstrate that the proposed model can decode pitch contours with modest errors, achieving performance comparable to state-of-the-art EEG regression methods. Moreover, speaker-normalized pitch contours were decoded more accurately, supporting the neural encoding of relative pitch.

cs.SD↗

arXiv2025

Beyond Manual Transcripts: The Potential of Automated Speech Recognition Errors in Improving Alzheimer's Disease Detection

Recent breakthroughs in Automatic Speech Recognition (ASR) have enabled fully automated Alzheimer's Disease (AD) detection using ASR transcripts. Nonetheless, the impact of ASR errors on AD detection remains poorly understood. This paper fills the gap. We conduct a comprehensive study on AD detection using transcripts from various ASR models and their synthesized speech on the ADReSS dataset. Experimental results reveal that certain ASR transcripts (ASR-synthesized speech) outperform manual transcripts (manual-synthesized speech) in detection accuracy, suggesting that ASR errors may provide valuable cues for improving AD detection. Additionally, we propose a cross-attention-based interpretability model that not only identifies these cues but also achieves superior or comparable performance to the baseline. Furthermore, we utilize this model to unveil AD-related patterns within pre-trained embeddings. Our study offers novel insights into the potential of ASR models for AD detection.

eess.AS↗

arXiv2025

AOR: Anatomical Ontology-Guided Reasoning for Medical Large Multimodal Model in Chest X-Ray Interpretation

Chest X-rays (CXRs) are the most frequently performed imaging examinations in clinical settings. Recent advancements in Large Multimodal Models (LMMs) have enabled automated CXR interpretation, enhancing diagnostic accuracy and efficiency. However, despite their strong visual understanding, current Medical LMMs (MLMMs) still face two major challenges: (1) Insufficient region-level understanding and interaction, and (2) Limited accuracy and interpretability due to single-step reasoning. In this paper, we empower MLMMs with anatomy-centric reasoning capabilities to enhance their interactivity and explainability. Specifically, we first propose an Anatomical Ontology-Guided Reasoning (AOR) framework, which centers on cross-modal region-level information to facilitate multi-step reasoning. Next, under the guidance of expert physicians, we develop AOR-Instruction, a large instruction dataset for MLMMs training. Our experiments demonstrate AOR's superior performance in both VQA and report generation tasks.

cs.CV↗

arXiv2025

QMix: Quality-aware Learning with Mixed Noise for Robust Retinal Disease Diagnosis

Due to the complexity of medical image acquisition and the difficulty of annotation, medical image datasets inevitably contain noise. Noisy data with wrong labels affects the robustness and generalization ability of deep neural networks. Previous noise learning methods mainly considered noise arising from images being mislabeled, i.e. label noise, assuming that all mislabeled images are of high image quality. However, medical images are prone to suffering extreme quality issues, i.e. data noise, where discriminative visual features are missing for disease diagnosis. In this paper, we propose a noise learning framework, termed as QMix, that learns a robust disease diagnosis model under mixed noise. QMix alternates between sample separation and quality-aware semisupervised training in each training epoch. In the sample separation phase, we design a joint uncertainty-loss criterion to effectively separate (1) correctly labeled images; (2) mislabeled images with high quality and (3) mislabeled images with low quality. In the semi-supervised training phase, we train a disease diagnosis model to learn robust feature representation from the separated samples. Specifically, we devise a sample-reweighing loss to mitigate the effect of mislabeled images with low quality during training. Meanwhile, a contrastive enhancement loss is proposed to further distinguish mislabeled images with low quality from correctly labeled images. QMix achieved state-of-the-art disease diagnosis performance on five public retinal image datasets and exhibited substantial improvement on robustness against mixed noise.

cs.CV↗

arXiv2025

EgoExo-Gen: Ego-centric Video Prediction by Watching Exo-centric Videos

Generating videos in the first-person perspective has broad application prospects in the field of augmented reality and embodied intelligence. In this work, we explore the cross-view video prediction task, where given an exo-centric video, the first frame of the corresponding ego-centric video, and textual instructions, the goal is to generate futur frames of the ego-centric video. Inspired by the notion that hand-object interactions (HOI) in ego-centric videos represent the primary intentions and actions of the current actor, we present EgoExo-Gen that explicitly models the hand-object dynamics for cross-view video prediction. EgoExo-Gen consists of two stages. First, we design a cross-view HOI mask prediction model that anticipates the HOI masks in future ego-frames by modeling the spatio-temporal ego-exo correspondence. Next, we employ a video diffusion model to predict future ego-frames using the first ego-frame and textual instructions, while incorporating the HOI masks as structural guidance to enhance prediction quality. To facilitate training, we develop an automated pipeline to generate pseudo HOI masks for both ego- and exo-videos by exploiting vision foundation models. Extensive experiments demonstrate that our proposed EgoExo-Gen achieves better prediction performance compared to previous video prediction models on the Ego-Exo4D and H2O benchmark datasets, with the HOI masks significantly improving the generation of hands and interactive objects in the ego-centric videos.

cs.CV↗

arXiv2025

Text-Promptable Propagation for Referring Medical Image Sequence Segmentation

Referring Medical Image Sequence Segmentation (Ref-MISS) is a novel and challenging task that aims to segment anatomical structures in medical image sequences (\emph{e.g.} endoscopy, ultrasound, CT, and MRI) based on natural language descriptions. This task holds significant clinical potential and offers a user-friendly advancement in medical imaging interpretation. Existing 2D and 3D segmentation models struggle to explicitly track objects of interest across medical image sequences, and lack support for nteractive, text-driven guidance. To address these limitations, we propose Text-Promptable Propagation (TPP), a model designed for referring medical image sequence segmentation. TPP captures the intrinsic relationships among sequential images along with their associated textual descriptions. Specifically, it enables the recognition of referred objects through cross-modal referring interaction, and maintains continuous tracking across the sequence via Transformer-based triple propagation, using text embeddings as queries. To support this task, we curate a large-scale benchmark, Ref-MISS-Bench, which covers 4 imaging modalities and 20 different organs and lesions. Experimental results on this benchmark demonstrate that TPP consistently outperforms state-of-the-art methods in both medical segmentation and referring video object segmentation.

cs.CV↗

arXiv2025

Human Simulacra: Benchmarking the Personification of Large Language Models

Large language models (LLMs) are recognized as systems that closely mimic aspects of human intelligence. This capability has attracted attention from the social science community, who see the potential in leveraging LLMs to replace human participants in experiments, thereby reducing research costs and complexity. In this paper, we introduce a framework for large language models personification, including a strategy for constructing virtual characters' life stories from the ground up, a Multi-Agent Cognitive Mechanism capable of simulating human cognitive processes, and a psychology-guided evaluation method to assess human simulations from both self and observational perspectives. Experimental results demonstrate that our constructed simulacra can produce personified responses that align with their target characters. Our work is a preliminary exploration which offers great potential in practical applications. All the code and datasets will be released, with the hope of inspiring further investigations. Our code and dataset are available at: https://github.com/hasakiXie123/Human-Simulacra.

cs.CY↗

arXiv2025

Recent Advances of 6G Ultra-Massive MIMO Technologies in Spatial and Beam Domains

To explore the full potential of ultra-massive multiple-input multiple-output (MIMO) communication systems, it is fundamental to understand new ultra-massive MIMO channel characteristics and establish pervasive channel models. On this basis, large dimensional spatial-temporal transmission and random access technologies need to be investigated and evaluated for better practical implementation. Firstly, this paper reviews recent advances of ultra-massive MIMO technologies in the traditional spatial domain, including wireless channel characterization and modeling, channel estimation, spatial multiplexing, and precoding. Secondly, considering the dramatic increase of base station (BS) antennas and access users in ultra-massive MIMO systems, the confronted high dimensional complexity and computing burden of these ultra-massive MIMO technologies are indicated. To provide efficient and systematic solution, the emerging tendency to transform related technologies from the traditional spatial domain to beam domain is introduced. The utilities of large sparsity merit, reduced energy consumption, and improved usage of radio frequency (RF) chains in the beam domain channel are elaborated. At last, future challenges of ultra-massive MIMO communication systems are discussed.

cs.IT↗

arXiv2024

Leveraging Prompt Learning and Pause Encoding for Alzheimer's Disease Detection

Compared to other clinical screening techniques, speech-and-language-based automated Alzheimer's disease (AD) detection methods are characterized by their non-invasiveness, cost-effectiveness, and convenience. Previous studies have demonstrated the efficacy of fine-tuning pre-trained language models (PLMs) for AD detection. However, the objective of this traditional fine-tuning method, which involves inputting only transcripts, is inconsistent with the masked language modeling (MLM) task used during the pre-training phase of PLMs. In this paper, we investigate prompt-based fine-tuning of PLMs, converting the classification task into a MLM task by inserting prompt templates into the transcript inputs. We also explore the impact of incorporating pause information from forced alignment into manual transcripts. Additionally, we compare the performance of various automatic speech recognition (ASR) models and select the Whisper model to generate ASR-based transcripts for comparison with manual transcripts. Furthermore, majority voting and ensemble techniques are applied across different PLMs (BERT and RoBERTa) using different random seeds. Ultimately, we obtain maximum detection accuracy of 95.8% (with mean 87.9%, std 3.3%) using manual transcripts, achieving state-of-the-art performance for AD detection using only transcripts on the ADReSS test set.

eess.AS↗