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Sandro Meloni

Publications and source records attributed to Sandro Meloni.

35 records · Page 2Linked to original sources

Vector-borne epidemics driven by human mobility

Vector-borne epidemics are the result of the combination of different factors such as the crossed contagions between humans and vectors, their demographic distribution and human mobility among others. The current availability of information about the former ingredients demands their incorporation to current mathematical models for vector-borne disease transmission. Here, relying on metapopulation dynamics, we propose a framework whose results are in fair agreement with those obtained from mechanistic simulations. This framework allows us to derive an expression of the epidemic threshold capturing with high accuracy the conditions leading to the onset of epidemics. Driven by these insights, we obtain a prevalence indicator to rank the patches according to the risk of being affected by a vector-borne disease. We illustrate the utility of this epidemic risk indicator by reproducing the spatial distribution Dengue cases reported in the city of Santiago de Cali (Colombia) from 2015 to 2016.

physics.soc-ph↗

Markovian approach to tackle the interaction of simultaneous diseases

The simultaneous emergence of several abrupt disease outbreaks or the extinction of some serotypes of multi-strain diseases are fingerprints of the interaction between pathogens spreading within the same population. Here, we propose a general and versatile benchmark to address the unfolding of both cooperative and competitive interacting diseases. We characterize the explosive transitions between the disease-free and the epidemic regimes arising from the cooperation between pathogens, and show the critical degree of cooperation needed for the onset of such abrupt transitions. For the competing diseases, we characterize the mutually exclusive case and derive analytically the transition point between the full-dominance phase, in which only one pathogen propagates, and the coexistence regime. Finally, we use this framework to analyze the behavior of the former transition point as the competition between pathogens is relaxed.

physics.soc-ph↗

Explore with caution: mapping the evolution of scientific interest in Physics

In the book The Essential Tension Thomas Kuhn described the conflict between tradition and innovation in scientific research --i.e., the desire to explore new promising areas, counterposed to the need to capitalize on the work done in the past. While it is true that along their careers many scientists probably felt this tension, only few works have tried to quantify it. Here, we address this question by analyzing a large-scale dataset, containing all the papers published by the American Physical Society (APS) in more than $25$ years, which allows for a better understanding of scientists' careers evolution in Physics. We employ the Physics and Astronomy Classification Scheme (PACS) present in each paper to map the scientific interests of $181,397$ authors and their evolution along the years. Our results indeed confirm the existence of the `essential tension' with scientists balancing between exploring the boundaries of their area and exploiting previous work. In particular, we found that although the majority of physicists change the topics of their research, they stay within the same broader area thus exploring with caution new scientific endeavors. Furthermore, we quantify the flows of authors moving between different subfields and pinpoint which areas are more likely to attract or donate researchers to the other ones. Overall, our results depict a very distinctive portrait of the evolution of research interests in Physics and can help in designing specific policies for the future.

physics.soc-ph↗

Topical alignment in online social systems

Understanding the dynamics of social interactions is crucial to comprehend human behavior. The emergence of online social media has enabled access to data regarding people relationships at a large scale. Twitter, specifically, is an information oriented network, with users sharing and consuming information. In this work, we study whether users tend to be in contact with people interested in similar topics, i.e., if they are topically aligned. To do so, we propose an approach based on the use of hashtags to extract information topics from Twitter messages and model users' interests. Our results show that, on average, users are connected with other users similar to them. Furthermore, we show that topical alignment provides interesting information that can eventually allow inferring users' connectivity. Our work, besides providing a way to assess the topical similarity of users, quantifies topical alignment among individuals, contributing to a better understanding of how complex social systems are structured.

physics.soc-ph↗

Impact of origin-destination information in epidemic spreading

The networked structure of contacts shapes the spreading of epidemic processes. Recent advances on network theory have improved our understanding of the epidemic processes at large scale. The relevance of several considerations still needs to be evaluated in the study of epidemic spreading. One of them is that of accounting for the influence of origin and destination patterns in the flow of the carriers of an epidemic. Here we compute origin-destination patterns compatible with empirical data of coarse grained flows in the air transportation network. We study the incidence of epidemic processes in a metapopulation approach considering different alternatives to the flows prior knowledge. The data-driven scenario where the estimation of origin and destination flows is considered turns out to be relevant to assess the impact of the epidemics at a microscopic level (in our scenario, which populations are infected). However, this information is irrelevant to assess its macroscopic incidence (fraction of infected populations). These results are of interest to implement even better computational platforms to forecast epidemic incidence.

physics.soc-ph↗

From degree-correlated to payoff-correlated activity for an optimal resolution of social dilemmas

An active participation of players in evolutionary games depends on several factors, ranging from personal stakes to the properties of the interaction network. Diverse activity patterns thus have to be taken into account when studying the evolution of cooperation in social dilemmas. Here we study the weak prisoner's dilemma game, where the activity of each player is determined in a probabilistic manner either by its degree or by its payoff. While degree-correlated activity introduces cascading failures of cooperation that are particularly severe on scale-free networks with frequently inactive hubs, payoff-correlated activity provides a more nuanced activity profile, which ultimately hinders systemic breakdowns of cooperation. To determine optimal conditions for the evolution of cooperation, we introduce an exponential decay to payoff-correlated activity that determines how fast the activity of a player returns to its default state. We show that there exists an intermediate decay rate, at which the resolution of the social dilemma is optimal. This can be explained by the emerging activity patterns of players, where the inactivity of hubs is compensated effectively by the increased activity of average-degree players, who through their collective influence in the network sustain a higher level of cooperation. The sudden drops in the fraction of cooperators observed with degree-correlated activity therefore vanish, and so does the need for the lengthy spatiotemporal reorganization of compact cooperative clusters. The absence of such asymmetric dynamic instabilities thus leads to an optimal resolution of social dilemmas, especially when the conditions for the evolution of cooperation are strongly adverse.

physics.soc-ph↗

Human mobility networks and persistence of rapidly mutating pathogens

Rapidly mutating pathogens may be able to persist in the population and reach an endemic equilibrium by escaping hosts' acquired immunity. For such diseases, multiple biological, environmental and population-level mechanisms determine the dynamics of the outbreak, including pathogen's epidemiological traits (e.g. transmissibility, infectious period and duration of immunity), seasonality, interaction with other circulating strains and hosts' mixing and spatial fragmentation. Here, we study a susceptible-infected-recovered-susceptible model on a metapopulation where individuals are distributed in subpopulations connected via a network of mobility flows. Through extensive numerical simulations, we explore the phase space of pathogen's persistence and map the dynamical regimes of the pathogen following emergence. Our results show that spatial fragmentation and mobility play a key role in the persistence of the disease whose maximum is reached at intermediate mobility values. We describe the occurrence of different phenomena including local extinction and emergence of epidemic waves, and assess the conditions for large scale spreading. Findings are highlighted in reference to previous works and to real scenarios. Our work uncovers the crucial role of hosts' mobility on the ecological dynamics of rapidly mutating pathogens, opening the path for further studies on disease ecology in the presence of a complex and heterogeneous environment.

physics.soc-ph↗

Epidemic Spreading in Random Rectangular Networks

The use of network theory to model disease propagation on populations introduces important elements of reality to the classical epidemiological models. The use of random geometric graphs (RGG) is one of such network models that allows for the consideration of spatial properties on disease propagation. In certain real-world scenarios -like in the analysis of a disease propagating through plants- the shape of the plots and fields where the host of the disease is located may play a fundamental role on the propagation dynamics. Here we consider a generalization of the RGG to account for the variation of the shape of the plots/fields where the hosts of a disease are allocated. We consider a disease propagation taking place on the nodes of a random rectangular graph (RRG) and we consider a lower bound for the epidemic threshold of a Susceptible-Infected-Susceptible (SIS) or Susceptible-Infected-Recovered (SIR) model on these networks. Using extensive numerical simulations and based on our analytical results we conclude that (ceteris paribus) the elongation of the plot/field in which the nodes are distributed makes the network more resilient to the propagation of a disease due to the fact that the epidemic threshold increases with the elongation of the rectangle. These results agree with accumulated empirical evidence and simulation results about the propagation of diseases on plants in plots/fields of the same area and different shapes.

physics.soc-ph↗

A multilayer perspective for the analysis of urban transportation systems

Public urban mobility systems are composed by several transportation modes connected together. Most studies in urban mobility and planning often ignore the multi-layer nature of transportation systems considering only aggregated versions of this complex scenario. In this work we present a model for the representation of the transportation system of an entire city as a multiplex network. Using two different perspectives, one in which each line is a layer and one in which lines of the same transportation mode are grouped together, we study the interconnected structure of 9 different cities in Europe raging from small towns to mega-cities like London and Berlin highlighting their vulnerabilities and possible improvements. Finally, for the city of Zaragoza in Spain, we also consider data about service schedule and waiting times, which allow us to create a simple yet realistic model for urban mobility able to reproduce real-world facts and to test for network improvements.

physics.soc-ph↗

Heterogeneous resource allocation can change social hierarchy in public goods games

Public Goods Games represent one of the most useful tools to study group interactions between individuals. However, even if they could provide an explanation for the emergence and stability of cooperation in modern societies, they are not able to reproduce some key features observed in social and economical interactions. The typical shape of wealth distribution - known as Pareto Law - and the microscopic organization of wealth production are two of them. Here, we introduce a modification to the classical formulation of Public Goods Games that allows for the emergence of both of these features from first principles. Unlike traditional Public Goods Games on networks, where players contribute equally to all the games in which they participate, we allow individuals to redistribute their contribution according to what they earned in previous rounds. Results from numerical simulations show that not only a Pareto distribution for the payoffs naturally emerges but also that if players don't invest enough in one round they can act as defectors even if they are formally cooperators. Finally, we also show that the players self-organize in a very productive backbone that covers almost perfectly the minimum spanning tree of the underlying interaction network. Our results not only give an explanation for the presence of the wealth heterogeneity observed in real data but also points to a conceptual change regarding how cooperation is defined in collective dilemmas.

physics.soc-ph↗

Dynamic instability of cooperation due to diverse activity patterns in evolutionary social dilemmas

Individuals might abstain from participating in an instance of an evolutionary game for various reasons, ranging from lack of interest to risk aversion. In order to understand the consequences of such diverse activity patterns on the evolution of cooperation, we study a weak prisoner's dilemma where each player's participation is probabilistic rather than certain. Players that do not participate get a null payoff and are unable to replicate. We show that inactivity introduces cascading failures of cooperation, which are particularly severe on scale-free networks with frequently inactive hubs. The drops in the fraction of cooperators are sudden, while the spatiotemporal reorganization of compact cooperative clusters, and thus the recovery, takes time. Nevertheless, if the activity of players is directly proportional to their degree, or if the interaction network is not strongly heterogeneous, the overall evolution of cooperation is not impaired. This is because inactivity negatively affects the potency of low-degree defectors, who are hence unable to utilize on their inherent evolutionary advantage. Between cascading failures, the fraction of cooperators is therefore higher than usual, which lastly balances out the asymmetric dynamic instabilities that emerge due to intermittent blackouts of cooperative hubs.

physics.soc-ph↗

Characterising two-pathogen competition in spatially structured environments

Different pathogens spreading in the same host population often generate complex co-circulation dynamics because of the many possible interactions between the pathogens and the host immune system, the host life cycle, and the space structure of the population. Here we focus on the competition between two acute infections and we address the role of host mobility and cross-immunity in shaping possible dominance/co-dominance regimes. Host mobility is modelled as a network of traveling flows connecting nodes of a metapopulation, and the two-pathogen dynamics is simulated with a stochastic mechanistic approach. Results depict a complex scenario where, according to the relation among the epidemiological parameters of the two pathogens, mobility can either be non-influential for the competition dynamics or play a critical role in selecting the dominant pathogen. The characterisation of the parameter space can be explained in terms of the trade-off between pathogen's spreading velocity and its ability to diffuse in a sparse environment. Variations in the cross-immunity level induce a transition between presence and absence of competition. The present study disentangles the role of the relevant biological and ecological factors in the competition dynamics, and provides relevant insights into the spatial ecology of infectious diseases.

q-bio.PE↗

Dynamics of interacting diseases

Current modeling of infectious diseases allows for the study of complex and realistic scenarios that go from the population to the individual level of description. However, most epidemic models assume that the spreading process takes place on a single level (be it a single population, a meta-population system or a network of contacts). In particular, interdependent contagion phenomena can only be addressed if we go beyond the scheme one pathogen-one network. In this paper, we propose a framework that allows describing the spreading dynamics of two concurrent diseases. Specifically, we characterize analytically the epidemic thresholds of the two diseases for different scenarios and also compute the temporal evolution characterizing the unfolding dynamics. Results show that there are regions of the parameter space in which the onset of a disease's outbreak is conditioned to the prevalence levels of the other disease. Moreover, we show, for the SIS scheme, that under certain circumstances, finite and not vanishing epidemic thresholds are found even at the thermodynamic limit for scale-free networks. For the SIR scenario, the phenomenology is richer and additional interdependencies show up. We also find that the secondary thresholds for the SIS and SIR models are different, which results directly from the interaction between both diseases. Our work thus solve an important problem and pave the way towards a more comprehensive description of the dynamics of interacting diseases.

physics.soc-ph↗

Host mobility drives pathogen competition in spatially structured populations

Interactions among multiple infectious agents are increasingly recognized as a fundamental issue in the understanding of key questions in public health, regarding pathogen emergence, maintenance, and evolution. The full description of host-multipathogen systems is however challenged by the multiplicity of factors affecting the interaction dynamics and the resulting competition that may occur at different scales, from the within-host scale to the spatial structure and mobility of the host population. Here we study the dynamics of two competing pathogens in a structured host population and assess the impact of the mobility pattern of hosts on the pathogen competition. We model the spatial structure of the host population in terms of a metapopulation network and focus on two strains imported locally in the system and having the same transmission potential but different infectious periods. We find different scenarios leading to competitive success of either one of the strain or to the codominance of both strains in the system. The dominance of the strain characterized by the shorter or longer infectious period depends exclusively on the structure of the population and on the the mobility of hosts across patches. The proposed modeling framework allows the integration of other relevant epidemiological, environmental and demographic factors opening the path to further mathematical and computational studies of the dynamics of multipathogen systems.

q-bio.PE↗

Emergence of influential spreaders in modified rumor models

The burst in the use of online social networks over the last decade has provided evidence that current rumor spreading models miss some fundamental ingredients in order to reproduce how information is disseminated. In particular, recent literature has revealed that these models fail to reproduce the fact that some nodes in a network have an influential role when it comes to spread a piece of information. In this work, we introduce two mechanisms with the aim of filling the gap between theoretical and experimental results. The first model introduces the assumption that spreaders are not always active whereas the second model considers the possibility that an ignorant is not interested in spreading the rumor. In both cases, results from numerical simulations show a higher adhesion to real data than classical rumor spreading models. Our results shed some light on the mechanisms underlying the spreading of information and ideas in large social systems and pave the way for more realistic diffusion models.

physics.soc-ph↗

Influence of Topological Features on Spatially-Structured Evolutionary Algorithms Dynamics

In the last decades, complex networks theory significantly influenced other disciplines on the modeling of both static and dynamic aspects of systems observed in nature. This work aims to investigate the effects of networks' topological features on the dynamics of an evolutionary algorithm, considering in particular the ability to find a large number of optima on multi-modal problems. We introduce a novel spatially-structured evolutionary algorithm and we apply it on two combinatorial problems: ONEMAX and the multi-modal NMAX. Considering three different network models we investigate the relationships between their features, algorithm's convergence and its ability to find multiple optima (for the multi-modal problem). In order to perform a deeper analysis we investigate the introduction of weighted graphs with time-varying weights. The results show that networks with a large Average Path Length lead to an higher number of optima and a consequent slow exploration dynamics (i.e. low First Hitting Time). Furthermore, the introduction of weighted networks shows the possibility to tune algorithm's dynamics during its execution with the parameter related with weights' change. This work gives a first answer about the effects of various graph topologies on the diversity of evolutionary algorithms and it describes a simple but powerful algorithmic framework which allows to investigate many aspects of ssEAs dynamics.

cs.NE↗

Local Empathy provides Global Minimization of Congestion in Communication Networks

We present a novel mechanism to avoid congestion in complex networks based on local knowledge of traffic conditions and the ability of routers to self-coordinate their dynamical behavior. In particular, routers make use of local information about traffic conditions to either reject or accept information packets from their neighbors. We show that when nodes are only aware of their own congestion state they self-organize into a hierarchical configuration that delays remarkably the onset of congestion although, leading to a sharp first-order like congestion transition. We also consider the case when nodes are aware of the congestion state of their neighbors. In this case, we show that empathy between nodes is strongly beneficial to the overall performance of the system and it is possible to achieve larger values for the critical load together with a smooth, second-order like, transition. Finally, we show how local empathy minimize the impact of congestion as much as global minimization. Therefore, here we present an outstanding example of how local dynamical rules can optimize the system's functioning up to the levels reached using global knowledge.

physics.soc-ph↗