arXiv subjects

Sishen Yuan

Publications and source records attributed to Sishen Yuan.

7 recordsLinked to original sources

arXiv2026

MagCeptor: Encoding Broadcast-Addressable Logic into Magnetic Receptors

Multicellular coordination relies on broadcast-addressable receptors, yet engineered magnetic systems face an addressability bottleneck because global fields intrinsically conflate power and control. Here, we introduce MagCeptors to resolve this by encoding selectivity directly into magnetic topology. Establishing an energetic isomorphism with biological receptors, these arrays utilize local couplings to shape potential landscapes where global field vectors act as spatial keys, triggering deterministic snap-through instabilities. This architecture decouples force from source distance, achieving a density of 385 mN/mm3 (>50-fold increase over prior art). We validate this primitive through signal demultiplexing, embodied sequential logic, and untethered distributed networking. This framework enables distributed systems to orchestrate complex tasks without tethers or electronics, relying solely on the intrinsic logic of matter.

eess.SY↗

arXiv2026

Anatomical Landmark-Guided Deep Reinforcement Learning for Autonomous Gastric Navigation

Wireless capsule endoscopy (WCE) enables painless visualization of the gastrointestinal tract, but its diagnostic potential is limited by incomplete mucosal coverage and poor transferability of existing navigation methods across patient anatomies. We propose a transferable, anatomical landmarkguided deep reinforcement learning (AL-DRL) framework for autonomous gastric navigation. Leveraging a lightweight edgecontour-depth fusion module, our policy operates on stable, lowdimensional landmark coordinates rather than high-dimensional video streams, effectively bridging the sim-to-real gap. In simulations across eight patient-derived models, the method achieves over 97% coverage within 50 seconds, significantly outperforming vanilla PPO, SAC, and DQN agents. A two-stage sim-to-real pipeline with an adaptive dynamic programming controller actively mitigates physical disturbances. Ex-vivo experiments demonstrate a mean coverage of 87% and a 53% reduction in procedure time compared with expert manual control.

cs.RO↗

arXiv2025

Adjusting Tissue Puncture Omnidirectionally In Situ with Pneumatic Rotatable Biopsy Mechanism and Hierarchical Airflow Management in Tortuous Luminal Pathways

In situ tissue biopsy with an endoluminal catheter is an efficient approach for disease diagnosis, featuring low invasiveness and few complications. However, the endoluminal catheter struggles to adjust the biopsy direction by distal endoscope bending or proximal twisting for tissue sampling within the tortuous luminal organs, due to friction-induced hysteresis and narrow spaces. Here, we propose a pneumatically-driven robotic catheter enabling the adjustment of the sampling direction without twisting the catheter for an accurate in situ omnidirectional biopsy. The distal end of the robotic catheter consists of a pneumatic bending actuator for the catheter's deployment in torturous luminal organs and a pneumatic rotatable biopsy mechanism (PRBM). By hierarchical airflow control, the PRBM can adjust the biopsy direction under low airflow and deploy the biopsy needle with higher airflow, allowing for rapid omnidirectional sampling of tissue in situ. This paper describes the design, modeling, and characterization of the proposed robotic catheter, including repeated deployment assessments of the biopsy needle, puncture force measurement, and validation via phantom tests. The PRBM prototype has six sampling directions evenly distributed across 360 degrees when actuated by a positive pressure of 0.3 MPa. The pneumatically-driven robotic catheter provides a novel biopsy strategy, potentially facilitating in situ multidirectional biopsies in tortuous luminal organs with minimum invasiveness.

cs.RO↗

arXiv2024

V$^2$-SfMLearner: Learning Monocular Depth and Ego-motion for Multimodal Wireless Capsule Endoscopy

Deep learning can predict depth maps and capsule ego-motion from capsule endoscopy videos, aiding in 3D scene reconstruction and lesion localization. However, the collisions of the capsule endoscopies within the gastrointestinal tract cause vibration perturbations in the training data. Existing solutions focus solely on vision-based processing, neglecting other auxiliary signals like vibrations that could reduce noise and improve performance. Therefore, we propose V$^2$-SfMLearner, a multimodal approach integrating vibration signals into vision-based depth and capsule motion estimation for monocular capsule endoscopy. We construct a multimodal capsule endoscopy dataset containing vibration and visual signals, and our artificial intelligence solution develops an unsupervised method using vision-vibration signals, effectively eliminating vibration perturbations through multimodal learning. Specifically, we carefully design a vibration network branch and a Fourier fusion module, to detect and mitigate vibration noises. The fusion framework is compatible with popular vision-only algorithms. Extensive validation on the multimodal dataset demonstrates superior performance and robustness against vision-only algorithms. Without the need for large external equipment, our V$^2$-SfMLearner has the potential for integration into clinical capsule robots, providing real-time and dependable digestive examination tools. The findings show promise for practical implementation in clinical settings, enhancing the diagnostic capabilities of doctors.

cs.CV↗

arXiv2024

EndoUIC: Promptable Diffusion Transformer for Unified Illumination Correction in Capsule Endoscopy

Wireless Capsule Endoscopy (WCE) is highly valued for its non-invasive and painless approach, though its effectiveness is compromised by uneven illumination from hardware constraints and complex internal dynamics, leading to overexposed or underexposed images. While researchers have discussed the challenges of low-light enhancement in WCE, the issue of correcting for different exposure levels remains underexplored. To tackle this, we introduce EndoUIC, a WCE unified illumination correction solution using an end-to-end promptable diffusion transformer (DiT) model. In our work, the illumination prompt module shall navigate the model to adapt to different exposure levels and perform targeted image enhancement, in which the Adaptive Prompt Integration (API) and Global Prompt Scanner (GPS) modules shall further boost the concurrent representation learning between the prompt parameters and features. Besides, the U-shaped restoration DiT model shall capture the long-range dependencies and contextual information for unified illumination restoration. Moreover, we present a novel Capsule-endoscopy Exposure Correction (CEC) dataset, including ground-truth and corrupted image pairs annotated by expert photographers. Extensive experiments against a variety of state-of-the-art (SOTA) methods on four datasets showcase the effectiveness of our proposed method and components in WCE illumination restoration, and the additional downstream experiments further demonstrate its utility for clinical diagnosis and surgical assistance.

eess.IV↗

arXiv2024

Magnetic-Guided Flexible Origami Robot toward Long-Term Phototherapy of H. pylori in the Stomach

Helicobacter pylori, a pervasive bacterial infection associated with gastrointestinal disorders such as gastritis, peptic ulcer disease, and gastric cancer, impacts approximately 50% of the global population. The efficacy of standard clinical eradication therapies is diminishing due to the rise of antibiotic-resistant strains, necessitating alternative treatment strategies. Photodynamic therapy (PDT) emerges as a promising prospect in this context. This study presents the development and implementation of a magnetically-guided origami robot, incorporating flexible printed circuit units for sustained and stable phototherapy of Helicobacter pylori. Each integrated unit is equipped with wireless charging capabilities, producing an optimal power output that can concurrently illuminate up to 15 LEDs at their maximum intensity. Crucially, these units can be remotely manipulated via a magnetic field, facilitating both translational and rotational movements. We propose an open-loop manual control sequence that allows the formation of a stable, compliant triangular structure through the interaction of internal magnets. This adaptable configuration is uniquely designed to withstand the dynamic squeezing environment prevalent in real-world gastric applications. The research herein represents a significant stride in leveraging technology for innovative medical solutions, particularly in the management of antibiotic-resistant Helicobacter pylori infections.

eess.SY↗

arXiv2024

Chained Flexible Capsule Endoscope: Unraveling the Conundrum of Size Limitations and Functional Integration for Gastrointestinal Transitivity

Capsule endoscopes, predominantly serving diagnostic functions, provide lucid internal imagery but are devoid of surgical or therapeutic capabilities. Consequently, despite lesion detection, physicians frequently resort to traditional endoscopic or open surgical procedures for treatment, resulting in more complex, potentially risky interventions. To surmount these limitations, this study introduces a chained flexible capsule endoscope (FCE) design concept, specifically conceived to navigate the inherent volume constraints of capsule endoscopes whilst augmenting their therapeutic functionalities. The FCE's distinctive flexibility originates from a conventional rotating joint design and the incision pattern in the flexible material. In vitro experiments validated the passive navigation ability of the FCE in rugged intestinal tracts. Further, the FCE demonstrates consistent reptile-like peristalsis under the influence of an external magnetic field, and possesses the capability for film expansion and disintegration under high-frequency electromagnetic stimulation. These findings illuminate a promising path toward amplifying the therapeutic capacities of capsule endoscopes without necessitating a size compromise.

physics.med-ph↗