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Ville-Pekka Seppä

Publications and source records attributed to Ville-Pekka Seppä.

2 recordsLinked to original sources

WIPSNet: Deep Learning for Paediatric Wheeze Detection from Overnight Impedance Pneumography

Overnight impedance pneumography (IP) is used to monitor paediatric respiratory health. Its current clinical readout, the Expiratory Variability Index (EVI), compresses each IP recording into a single scalar and achieves an AUC of 0.633 for night-level wheeze classification. We introduce Wheeze Impedance Pneumography Scalogram Network (WIPSNet), a 3D ResNet operating on stacked continuous wavelet transform scalograms of overnight IP signals. On a 15-patient cohort (60 nights, 281 hours), WIPSNet achieves an AUC of $0.783 \pm 0.026$, outperforming EVI, a state-space model (Mamba), and two modern sleep-staging architectures. Performance peaks at a volumetric depth corresponding to 32 minutes of temporal context, suggesting that multi-scale temporal aggregation is important for modelling nocturnal respiratory dynamics. Overall, these results indicate that structured time-frequency representations combined with 3D convolutional architectures provide an effective approach for learning from long, irregular physiological time series.

cs.LG↗

Expiratory variability index (EVI) is associated with asthma risk, wheeze and lung function in infants with recurrent respiratory symptoms

Recurrent respiratory symptoms are common in infants but the paucity of lung function tests suitable for routine use in infants is a widely acknowledged clinical problem. In this study we evaluated tidal breathing variability (expiratory variability index, EVI) measured at home during sleep using impedance pneumography (IP) as a marker of lower airway obstruction in 36 infants (mean age 12.8 [range 6-23] months) with recurrent respiratory symptoms. Lowered EVI was associated with lower lung function (VmaxFRC), higher asthma risk, and obstructive symptoms, but not with nasal congestion. EVI measured using IP is a potential technique for lung function testing in infants.

q-bio.QM↗