arXiv subjects

Xiang Zhang

Publications and source records attributed to Xiang Zhang.

At least 127 records · Page 7Linked to original sources

arXiv2026

Data Augmentation for High-Fidelity Generation of CAR-T/NK Immunological Synapse Images

Chimeric antigen receptor (CAR)-T and NK cell immunotherapies have transformed cancer treatment, and recent studies suggest that the quality of the CAR-T/NK cell immunological synapse (IS) may serve as a functional biomarker for predicting therapeutic efficacy. Accurate detection and segmentation of CAR-T/NK IS structures using artificial neural networks (ANNs) can greatly increase the speed and reliability of IS quantification. However, a persistent challenge is the limited size of annotated microscopy datasets, which restricts the ability of ANNs to generalize. To address this challenge, we integrate two complementary data-augmentation frameworks. First, we employ Instance Aware Automatic Augmentation (IAAA), an automated, instance-preserving augmentation method that generates synthetic CAR-T/NK IS images and corresponding segmentation masks by applying optimized augmentation policies to original IS data. IAAA supports multiple imaging modalities (e.g., fluorescence and brightfield) and can be applied directly to CAR-T/NK IS images derived from patient samples. In parallel, we introduce a Semantic-Aware AI Augmentation (SAAA) pipeline that combines a diffusion-based mask generator with a Pix2Pix conditional image synthesizer. This second method enables the creation of diverse, anatomically realistic segmentation masks and produces high-fidelity CAR-T/NK IS images aligned with those masks, further expanding the training corpus beyond what IAAA alone can provide. Together, these augmentation strategies generate synthetic images whose visual and structural properties closely match real IS data, significantly improving CAR-T/NK IS detection and segmentation performance. By enhancing the robustness and accuracy of IS quantification, this work supports the development of more reliable imaging-based biomarkers for predicting patient response to CAR-T/NK immunotherapy.

cs.CV↗

arXiv2026

Mind-Brush: Integrating Agentic Cognitive Search and Reasoning into Image Generation

While text-to-image generation has achieved unprecedented fidelity, the vast majority of existing models function fundamentally as static text-to-pixel decoders. Consequently, they often fail to grasp implicit user intentions. Although emerging unified understanding-generation models have improved intent comprehension, they still struggle to accomplish tasks involving complex knowledge reasoning within a single model. Moreover, constrained by static internal priors, these models remain unable to adapt to the evolving dynamics of the real world. To bridge these gaps, we introduce Mind-Brush, a unified agentic framework that transforms generation into a dynamic, knowledge-driven workflow. Simulating a human-like 'think-research-create' paradigm, Mind-Brush actively retrieves multimodal evidence to ground out-of-distribution concepts and employs reasoning tools to resolve implicit visual constraints. To rigorously evaluate these capabilities, we propose Mind-Bench, a comprehensive benchmark comprising 500 distinct samples spanning real-time news, emerging concepts, and domains such as mathematical and Geo-Reasoning. Extensive experiments demonstrate that Mind-Brush significantly enhances the capabilities of unified models, realizing a zero-to-one capability leap for the Qwen-Image baseline on Mind-Bench, while achieving superior results on established benchmarks like WISE and RISE.

cs.CV↗

arXiv2026

How Far Are LLMs from Professional Poker Players? Revisiting Game-Theoretic Reasoning with Agentic Tool Use

As Large Language Models (LLMs) are increasingly applied in high-stakes domains, their ability to reason strategically under uncertainty becomes critical. Poker provides a rigorous testbed, requiring not only strong actions but also principled, game-theoretic reasoning. In this paper, we conduct a systematic study of LLMs in multiple realistic poker tasks, evaluating both gameplay outcomes and reasoning traces. Our analysis reveals LLMs fail to compete against traditional algorithms and identifies three recurring flaws: reliance on heuristics, factual misunderstandings, and a "knowing-doing" gap where actions diverge from reasoning. An initial attempt with behavior cloning and step-level reinforcement learning improves reasoning style but remains insufficient for accurate game-theoretic play. Motivated by these limitations, we propose ToolPoker, a tool-integrated reasoning framework that combines external solvers for GTO-consistent actions with more precise professional-style explanations. Experiments demonstrate that ToolPoker achieves state-of-the-art gameplay while producing reasoning traces that closely reflect game-theoretic principles.

cs.AI↗

arXiv2026

Engineering quantum Mpemba effect by Liouvillian skin effect

We propose a novel approach to engineer the quantum Mpemba effect (QME)-wherein an initial state farther from the steaty state relaxes faster than a closer one-by the Liouvillian skin effect (LSE) in open quantum systems. We show that, in the open quantum chain with LSE, QME can be easily realized by considering only the spatial profile of initial states, since the initial states localized on the left or right edges experience distinctive relaxation process (algebraic or exponential decay). This approach circumvents the necessity of careful initial-state design and fine-tuning of control parameter. Moreover, when the initial correlation matrix contains off-diagonal elements, we uncover a new kind of QME which manifest as two crossings in the Hilbert-Schmidt distance at different times. This work unveils the deep connection between QME and LSE, and provides a physically intuitive understanding of QME and straightforward pathway for the initial state preparation thereby enabling readily accessible experimental preparation.

quant-ph↗

arXiv2026

Information-Theoretic Secure Aggregation over Regular Graphs

Large-scale decentralized learning frameworks such as federated learning (FL), require both communication efficiency and strong data security, motivating the study of secure aggregation (SA). While information-theoretic SA is well understood in centralized and fully connected networks, its extension to decentralized networks with limited local connectivity remains largely unexplored. This paper introduces \emph{topological secure aggregation} (TSA), which studies one-shot, information-theoretically secure aggregation of neighboring users' inputs over arbitrary network topologies. We develop a unified linear design framework that characterizes TSA achievability through the spectral properties of the communication graph, specifically the kernel of a diagonally modulated adjacency matrix. For several representative classes of $d$-regular graphs including ring, prism and complete topologies, we establish the optimal communication and secret key rate region. In particular, to securely compute one symbol of the neighborhood sum, each user must (i) store at least one key symbol, (ii) broadcast at least one message symbol, and (iii) collectively, all users must hold at least $d$ i.i.d. key symbols. Notably, this total key requirement depends only on the \emph{neighborhood size} $d$, independent of the network size, revealing a fundamental limit of SA in decentralized networks with limited local connectivity.

cs.IT↗

arXiv2026

RM-Tools: Software for Analyzing Polarized Radio Spectra

Polarization observations using modern radio telescopes cover large numbers of frequency channels over broad bandwidths, and require advanced techniques to extract reliable scientific results. We present RM-Tools, analysis software for deriving polarization properties, such as Faraday rotation measures, from spectropolarimetric observations of linearly polarized radio sources. The software makes use of techniques such as rotation measure synthesis and QU-model fitting, along with many features to simplify and enhance the analysis of radio polarization data. RM-Tools is currently the main software that large-area polarization sky surveys such as POSSUM and VLASS deploy for science-ready data processing. The software code is freely available online and can be used with data from a wide range of telescopes.

astro-ph.IM↗

arXiv2026

Fundamental Limits of Hierarchical Secure Aggregation with Cyclic User Association

Secure aggregation is motivated by federated learning (FL) where a cloud server aims to compute an {aggregated} model (i.e., weights of deep neural networks) of the locally-trained models of numerous clients {through an iterative communication process}, while adhering to data security requirements. Hierarchical secure aggregation (HSA) extends this concept to a three-layer hierarchical network, where clustered users communicate with the server through an intermediate layer of relays. In HSA, beyond conventional server security, relay security is also enforced to ensure that the relays remain oblivious to the users' inputs (an abstraction of the local models in FL). {Existing studies on HSA that jointly consider communication and secret key generation efficiency typically assume that each user is associated with only one relay, limiting opportunities for coding across inter-cluster users to achieve efficient communication and key generation.} In this paper, we consider HSA with a cyclic association pattern where each user is connected to $B$ consecutive relays in a wrap-around manner. We propose an efficient aggregation scheme which includes a message design for the inputs inspired by gradient coding-a well-known technique for efficient communication in distributed computing-along with a highly non-trivial security key design.

cs.IT↗

arXiv2026

DeLog: An Efficient Log Compression Framework with Pattern Signature Synthesis

Parser-based log compression, which separates static templates from dynamic variables, is a promising approach to exploit the unique structure of log data. However, its performance on complex production logs is often unsatisfactory. This performance gap coincides with a known degradation in the accuracy of its core log parsing component on such data, motivating our investigation into a foundational yet unverified question: does higher parsing accuracy necessarily lead to better compression ratio? To answer this, we conduct the first empirical study quantifying this relationship and find that a higher parsing accuracy does not guarantee a better compression ratio. Instead, our findings reveal that compression ratio is dictated by achieving effective pattern-based grouping and encoding, i.e., the partitioning of tokens into low entropy, highly compressible groups. Guided by this insight, we design DeLog, a novel log compressor that implements a Pattern Signature Synthesis mechanism to achieve efficient pattern-based grouping. On 16 public and 10 production datasets, DeLog achieves state-of-the-art compression ratio and speed.

cs.SE↗

arXiv2026

On Resilient and Efficient Linear Secure Aggregation in Hierarchical Federated Learning

In this paper, we study the fundamental limits of hierarchical secure aggregation under unreliable communication. We consider a hierarchical network where each client connects to multiple relays, and both client-to-relay and relay-to-server links are intermittent. Under this setting, we characterize the minimum communication and randomness costs required to achieve robust secure aggregation. We then propose an optimal protocol that attains these minimum costs, and establish its optimality through a matching converse proof. In addition, we introduce an improved problem formulation that bridges the gap between existing information-theoretic secure aggregation protocols and practical real-world federated learning problems.

cs.DC↗

arXiv2026

Breaking Coordinate Overfitting: Geometry-Aware WiFi Sensing for Cross-Layout 3D Pose Estimation

WiFi-based 3D human pose estimation offers a low-cost and privacy-preserving alternative to vision-based systems for smart interaction. However, existing approaches rely on visual 3D poses as supervision and directly regress CSI to a camera-based coordinate system. We find that this practice leads to coordinate overfitting: models memorize deployment-specific WiFi transceiver layouts rather than only learning activity-relevant representations, resulting in severe generalization failures. To address this challenge, we present PerceptAlign, the first geometry-conditioned framework for WiFi-based cross-layout pose estimation. PerceptAlign introduces a lightweight coordinate unification procedure that aligns WiFi and vision measurements in a shared 3D space using only two checkerboards and a few photos. Within this unified space, it encodes calibrated transceiver positions into high-dimensional embeddings and fuses them with CSI features, making the model explicitly aware of device geometry as a conditional variable. This design forces the network to disentangle human motion from deployment layouts, enabling robust and, for the first time, layout-invariant WiFi pose estimation. To support systematic evaluation, we construct the largest cross-domain 3D WiFi pose estimation dataset to date, comprising 21 subjects, 5 scenes, 18 actions, and 7 device layouts. Experiments show that PerceptAlign reduces in-domain error by 12.3% and cross-domain error by more than 60% compared to state-of-the-art baselines. These results establish geometry-conditioned learning as a viable path toward scalable and practical WiFi sensing.

cs.HC↗

arXiv2026

A Bayesian Approach for Selecting Relevant External Data (BASE): Application to a study of Long-Term Outcomes in a Hemophilia Gene Therapy Trial

Gene therapies aim to address the root causes of diseases, particularly those stemming from rare genetic defects that can be life-threatening or severely debilitating. Although an increasing number of gene therapies have received regulatory approvals in recent years, understanding their long-term efficacy in trials with limited follow-up time remains challenging. To address this critical question, we propose a novel Bayesian framework designed to selectively integrate relevant external data with internal trial data to improve the inference of the durability of long-term efficacy. We proved that the proposed method has desired theoretical properties, such as identifying and favoring external subsets deemed relevant, where the relevance is defined as the similarity, induced by the marginal likelihood, between the generating mechanisms of the internal data and the selected external data. We also conducted comprehensive simulations to evaluate its performance under various scenarios. Furthermore, we apply this method to predict and infer the endogenous factor IX (FIX) levels of patients who receive Etranacogene dezaparvovec over the long-term. Our estimated long-term FIX levels, validated by recent trial data, indicate that Etranacogene dezaparvovec induces sustained FIX production. Together, the theoretical findings, simulation results, and successful application of this framework underscore its potential to address similar long-term effectiveness estimation and inference questions in real world applications.

stat.ME↗

arXiv2026

FORESTLLM: Large Language Models Make Random Forest Great on Few-shot Tabular Learning

Tabular data high-stakes critical decision-making in domains such as finance, healthcare, and scientific discovery. Yet, learning effectively from tabular data in few-shot settings, where labeled examples are scarce, remains a fundamental challenge. Traditional tree-based methods often falter in these regimes due to their reliance on statistical purity metrics, which become unstable and prone to overfitting with limited supervision. At the same time, direct applications of large language models (LLMs) often overlook its inherent structure, leading to suboptimal performance. To overcome these limitations, we propose FORESTLLM, a novel framework that unifies the structural inductive biases of decision forests with the semantic reasoning capabilities of LLMs. Crucially, FORESTLLM leverages the LLM only during training, treating it as an offline model designer that encodes rich, contextual knowledge into a lightweight, interpretable forest model, eliminating the need for LLM inference at test time. Our method is two-fold. First, we introduce a semantic splitting criterion in which the LLM evaluates candidate partitions based on their coherence over both labeled and unlabeled data, enabling the induction of more robust and generalizable tree structures under few-shot supervision. Second, we propose a one-time in-context inference mechanism for leaf node stabilization, where the LLM distills the decision path and its supporting examples into a concise, deterministic prediction, replacing noisy empirical estimates with semantically informed outputs. Across a diverse suite of few-shot classification and regression benchmarks, FORESTLLM achieves state-of-the-art performance.

cs.LG↗

arXiv2026

Optimal Communication and Key Rate Region for Hierarchical Secure Aggregation with User Collusion

Secure aggregation is concerned with the task of securely uploading the inputs of multiple users to an aggregation server without letting the server know the inputs beyond their summation. It finds broad applications in distributed machine learning paradigms such as federated learning (FL) where multiple clients, each having access to a proprietary dataset, periodically upload their locally trained models (abstracted as inputs) to a parameter server which then generates an aggregate (e.g., averaged) model that is sent back to the clients as an initializing point for a new round of local training. To enhance the data privacy of the clients, secure aggregation protocols are developed using techniques from cryptography to ensure that the server infers no more information of the users' inputs beyond the desired aggregated input, even if the server can collude with some users. Although laying the ground for understanding the fundamental utility-security trade-off in secure aggregation, the simple star client-server architecture cannot capture more complex network architectures used in practical systems. Motivated by hierarchical federated learning, we investigate the secure aggregation problem in a $3$-layer hierarchical network consisting of clustered users connecting to an aggregation server through an intermediate layer of relays. Besides the conventional server security which requires that the server learns nothing beyond the desired sum of inputs, relay security is also imposed so that the relays infer nothing about the users' inputs and remain oblivious. For such a hierarchical secure aggregation (HSA) problem, we characterize the optimal multifaceted trade-off between communication (in terms of user-to-relay and relay-to-server communication rates) and secret key generation efficiency (in terms of individual key and source key rates).

cs.IT↗

arXiv2026

DexH2R: Task-oriented Dexterous Manipulation from Human to Robots

Dexterous manipulation is a critical aspect of human capability, enabling interaction with a wide variety of objects. Recent advancements in learning from human demonstrations and teleoperation have enabled progress for robots in such ability. However, these approaches either require complex data collection such as costly human effort for eye-robot contact, or suffer from poor generalization when faced with novel scenarios. To solve both challenges, we propose a framework, DexH2R, that combines human hand motion retargeting with a task-oriented residual action policy, improving task performance by bridging the embodiment gap between human and robotic dexterous hands. Specifically, DexH2R learns the residual policy directly from retargeted primitive actions and task-oriented rewards, eliminating the need for labor-intensive teleoperation systems. Moreover, we incorporate test-time guidance for novel scenarios by taking in desired trajectories of human hands and objects, allowing the dexterous hand to acquire new skills with high generalizability. Extensive experiments in both simulation and real-world environments demonstrate the effectiveness of our work, outperforming prior state-of-the-arts by 40% across various settings.

cs.RO↗

arXiv2026

TFEC: Multivariate Time-Series Clustering via Temporal-Frequency Enhanced Contrastive Learning

Multivariate Time-Series (MTS) clustering is crucial for signal processing and data analysis. Although deep learning approaches, particularly those leveraging Contrastive Learning (CL), are prominent for MTS representation, existing CL-based models face two key limitations: 1) neglecting clustering information during positive/negative sample pair construction, and 2) introducing unreasonable inductive biases, e.g., destroying time dependence and periodicity through augmentation strategies, compromising representation quality. This paper, therefore, proposes a Temporal-Frequency Enhanced Contrastive (TFEC) learning framework. To preserve temporal structure while generating low-distortion representations, a temporal-frequency Co-EnHancement (CoEH) mechanism is introduced. Accordingly, a synergistic dual-path representation and cluster distribution learning framework is designed to jointly optimize cluster structure and representation fidelity. Experiments on six real-world benchmark datasets demonstrate TFEC's superiority, achieving 4.48% average NMI gains over SOTA methods, with ablation studies validating the design. The code of the paper is available at: https://github.com/yueliangy/TFEC.

cs.LG↗

arXiv2026

Optimal Rate Region for Multi-server Secure Aggregation with User Collusion

Secure aggregation is a fundamental primitive in privacy-preserving distributed learning systems, where an aggregator aims to compute the sum of users' inputs without revealing individual data. In this paper, we study a multi-server secure aggregation problem in a two-hop network consisting of multiple aggregation servers and multiple users per server, under the presence of user collusion. Each user communicates only with its associated server, while the servers exchange messages to jointly recover the global sum. We adopt an information-theoretic security framework, allowing up to $T$ users to collude with any server. We characterize the complete optimal rate region in terms of user-to-server communication rate, server-to-server communication rate, individual key rate, and source key rate. Our main result shows that the minimum communication and individual key rates are all one symbol per input symbol, while the optimal source key rate is given by $\min\{U+V+T-2,\, UV-1\}$, where $U$ denotes the number of servers and $V$ the number of users per server. The achievability is established via a linear key construction that ensures correctness and security against colluding users, while the converse proof relies on tight entropy bounds derived from correctness and security constraints. The results reveal a fundamental tradeoff between security and key efficiency and demonstrate that the multi-server architecture can significantly reduce the required key randomness compared to single-server secure aggregation. Our findings provide a complete information-theoretic characterization of secure aggregation in multi-server systems with user collusion.

cs.IT↗

arXiv2026

Hierarchical Secure Aggregation with Heterogeneous Security Constraints and Arbitrary User Collusion

In hierarchical secure aggregation (HSA), a server communicates with clustered users through an intermediate layer of relays to compute the sum of users' inputs under two security requirements -- server security and relay security. Server security requires that the server learns nothing beyond the desired sum even when colluding with a subset of users, while relay security requires that each relay remains oblivious to the users' inputs under collusion. Existing work on HSA enforces homogeneous security where \tit{all} inputs must be protected against \tit{any} subset of potential colluding users with sizes up to a predefined threshold. Such a \homo formulation cannot capture scenarios with \tit{\het} \secty \reqs where \diff users may demand various levels of protection. In this paper, we study hierarchical secure aggregation (HSA) with heterogeneous security requirements and arbitrary user collusion. Specifically, we consider scenarios where the inputs of certain groups of users must remain information-theoretically secure against inference by the server or any relay, even if the server or any relay colludes with an arbitrary subset of other users. Under server security, the server learns nothing about these protected inputs beyond the prescribed aggregate sum, despite any such collusion. Under relay security, each relay similarly obtains no information about the protected inputs under the same collusion model. We characterize the optimal communication rates achievable across all layers for all parameter regimes. Furthermore, we study the minimum source keys required at the users to ensure security. For this source key requirement, we provide tight characterizations in two broad regimes determined by the security and collusion constraints, and establish a general information-theoretic lower bound together with a bounded-gap achievable scheme for the remaining regime.

cs.IT↗

arXiv2026

Beyond Physical Labels: Redefining Domains for Robust WiFi-based Gesture Recognition

In this paper, we propose GesFi, a novel WiFi-based gesture recognition system that introduces WiFi latent domain mining to redefine domains directly from the data itself. GesFi first processes raw sensing data collected from WiFi receivers using CSI-ratio denoising, Short-Time Fast Fourier Transform, and visualization techniques to generate standardized input representations. It then employs class-wise adversarial learning to suppress gesture semantic and leverages unsupervised clustering to automatically uncover latent domain factors responsible for distributional shifts. These latent domains are then aligned through adversarial learning to support robust cross-domain generalization. Finally, the system is applied to the target environment for robust gesture inference. We deployed GesFi under both single-pair and multi-pair settings using commodity WiFi transceivers, and evaluated it across multiple public datasets and real-world environments. Compared to state-of-the-art baselines, GesFi achieves up to 78% and 50% performance improvements over existing adversarial methods, and consistently outperforms prior generalization approaches across most cross-domain tasks.

cs.HC↗