Searcharxiv⌕ Search

arXiv subjects

Xiaoying Tang

Publications and source records attributed to Xiaoying Tang.

At least 55 records · Page 3Linked to original sources

DWS-based microrheology of triblock copolymers

The thermally reversible phase transitions in aqueous solutions of the triblock copolymers known as Pluronic and their related textures are well-researched. However, their corresponding rheological properties are less studied. In particular, their high-temperature behavior is difficult to access with classical rheology. Here we demonstrated that Diffusing Wave Spectroscopy (DWS)-based microrheology allows us to study the phase transition and the associated viscoelastic properties of Pluronic F127 solutions for temperatures from 5 C to 80 C. From the measured intensity-autocorrelation functions we can extract effective viscosities and determine the critical micellization temperature and concentration. Moreover,the high EO/PO (arm-to-core) ratio of F127 and its polydispersity play a critical role in the high-temperature re-entrant liquid phase, due to decreasing solubility of PEO along with the dehydration of the PPO core. The microscopic viscoelastic moduli G'(ω) and G''(ω) help to determine these phase transitions and provide mechanical properties in the solid phase that are not readily accessible with standard multi-particle tracking techniques due to limited Brownian motion.

cond-mat.soft↗

Adaptive Prompt Structure Factorization: A Framework for Self-Discovering and Optimizing Compositional Prompt Programs

Automated prompt optimization is crucial for eliciting reliable reasoning from large language models (LLMs), yet most API-only prompt optimizers iteratively edit monolithic prompts, coupling components and obscuring credit assignment, limiting controllability, and wasting tokens. We propose Adaptive Prompt Structure Factorization (aPSF), an API-only framework (prompt-in/text-out; no access to model internals) that uses an Architect model to discover task-specific prompt structures as semantic factors. aPSF then performs interventional, single-factor updates: interventional factor-level scoring estimates each factor's marginal contribution via validation-performance changes, and error-guided factor selection routes updates to the current dominant failure source for more sample-efficient optimization. Across multiple advanced reasoning benchmarks, aPSF outperforms strong baselines including principle-aware optimizers, improving accuracy by up to +2.16 percentage points on average, and reduces optimization cost by 45--87% tokens on MultiArith while reaching peak validation in 1 step.

cs.CL↗

LUMOS: Universal Semi-Supervised OCT Retinal Layer Segmentation with Hierarchical Reliable Mutual Learning

Optical Coherence Tomography (OCT) layer segmentation faces challenges due to annotation scarcity and heterogeneous label granularities across datasets. While semi-supervised learning helps alleviate label scarcity, existing methods typically assume a fixed granularity, failing to fully exploit cross-granularity supervision. This paper presents LUMOS, a semi-supervised universal OCT retinal layer segmentation framework based on a Dual-Decoder Network with a Hierarchical Prompting Strategy (DDN-HPS) and Reliable Progressive Multi-granularity Learning (RPML). DDN-HPS combines a dual-branch architecture with a multi-granularity prompting strategy to effectively suppress pseudo-label noise propagation. Meanwhile, RPML introduces region-level reliability weighing and a progressive training approach that guides the model from easier to more difficult tasks, ensuring the reliable selection of cross-granularity consistency targets, thereby achieving stable cross-granularity alignment. Experiments on six OCT datasets demonstrate that LUMOS largely outperforms existing methods and exhibits exceptional cross-domain and cross-granularity generalization capability.

cs.CV↗

CRISP: Rank-Guided Iterative Squeezing for Robust Medical Image Segmentation under Domain Shift

Distribution shift in medical imaging remains a central bottleneck for the clinical translation of medical AI. Failure to address it can lead to severe performance degradation in unseen environments and exacerbate health inequities. Existing methods for domain adaptation are inherently limited by exhausting predefined possibilities through simulated shifts or pseudo-supervision. Such strategies struggle in the open-ended and unpredictable real world, where distribution shifts are effectively infinite. To address this challenge, we introduce an empirical law called ``Rank Stability of Positive Regions'', which states that the relative rank of predicted probabilities for positive voxels remains stable under distribution shift. Guided by this principle, we propose CRISP, a parameter-free and model-agnostic framework requiring no target-domain information. CRISP is the first framework to make segmentation based on rank rather than probabilities. CRISP simulates model behavior under distribution shift via latent feature perturbation, where voxel probability rankings exhibit two stable patterns: regions that consistently retain high probabilities (destined positives according to the principle) and those that remain low-probability (can be safely classified as negatives). Based on these patterns, we construct high-precision (HP) and high-recall (HR) priors and recursively refine them under perturbation. We then design an iterative training framework, making HP and HR progressively ``squeeze'' to the final segmentation. Extensive evaluations on multi-center cardiac MRI and CT-based lung vessel segmentation demonstrate CRISP's superior robustness, significantly outperforming state-of-the-art methods with striking HD95 reductions of up to 0.14 (7.0\% improvement), 1.90 (13.1\% improvement), and 8.39 (38.9\% improvement) pixels across multi-center, demographic, and modality shifts, respectively.

cs.CV↗

PIDP-Attack: Combining Prompt Injection with Database Poisoning Attacks on Retrieval-Augmented Generation Systems

Large Language Models (LLMs) have demonstrated remarkable performance across a wide range of applications. However, their practical deployment is often hindered by issues such as outdated knowledge and the tendency to generate hallucinations. To address these limitations, Retrieval-Augmented Generation (RAG) systems have been introduced, enhancing LLMs with external, up-to-date knowledge sources. Despite their advantages, RAG systems remain vulnerable to adversarial attacks, with data poisoning emerging as a prominent threat. Existing poisoning-based attacks typically require prior knowledge of the user's specific queries, limiting their flexibility and real-world applicability. In this work, we propose PIDP-Attack, a novel compound attack that integrates prompt injection with database poisoning in RAG. By appending malicious characters to queries at inference time and injecting a limited number of poisoned passages into the retrieval database, our method can effectively manipulate LLM response to arbitrary query without prior knowledge of the user's actual query. Experimental evaluations across three benchmark datasets (Natural Questions, HotpotQA, MS-MARCO) and eight LLMs demonstrate that PIDP-Attack consistently outperforms the original PoisonedRAG. Specifically, our method improves attack success rates by 4% to 16% on open-domain QA tasks while maintaining high retrieval precision, proving that the compound attack strategy is both necessary and highly effective.

cs.CR↗

4DEquine: Disentangling Motion and Appearance for 4D Equine Reconstruction from Monocular Video

4D reconstruction of equine family (e.g. horses) from monocular video is important for animal welfare. Previous mainstream 4D animal reconstruction methods require joint optimization of motion and appearance over a whole video, which is time-consuming and sensitive to incomplete observation. In this work, we propose a novel framework called 4DEquine by disentangling the 4D reconstruction problem into two sub-problems: dynamic motion reconstruction and static appearance reconstruction. For motion, we introduce a simple yet effective spatio-temporal transformer with a post-optimization stage to regress smooth and pixel-aligned pose and shape sequences from video. For appearance, we design a novel feed-forward network that reconstructs a high-fidelity, animatable 3D Gaussian avatar from as few as a single image. To assist training, we create a large-scale synthetic motion dataset, VarenPoser, which features high-quality surface motions and diverse camera trajectories, as well as a synthetic appearance dataset, VarenTex, comprising realistic multi-view images generated through multi-view diffusion. While training only on synthetic datasets, 4DEquine achieves state-of-the-art performance on real-world APT36K and AiM datasets, demonstrating the superiority of 4DEquine and our new datasets for both geometry and appearance reconstruction. Comprehensive ablation studies validate the effectiveness of both the motion and appearance reconstruction network. Project page: https://luoxue-star.github.io/4DEquine_Project_Page/.

cs.CV↗

A Vision-Language Foundation Model for Zero-shot Clinical Collaboration and Automated Concept Discovery in Dermatology

Medical foundation models have shown promise in controlled benchmarks, yet widespread deployment remains hindered by reliance on task-specific fine-tuning. Here, we introduce DermFM-Zero, a dermatology vision-language foundation model trained via masked latent modelling and contrastive learning on over 4 million multimodal data points. We evaluated DermFM-Zero across 20 benchmarks spanning zero-shot diagnosis and multimodal retrieval, achieving state-of-the-art performance without task-specific adaptation. We further evaluated its zero-shot capabilities in three multinational reader studies involving over 1,100 clinicians. In primary care settings, AI assistance enabled general practitioners to nearly double their differential diagnostic accuracy across 98 skin conditions. In specialist settings, the model significantly outperformed board-certified dermatologists in multimodal skin cancer assessment. In collaborative workflows, AI assistance enabled non-experts to surpass unassisted experts while improving management appropriateness. Finally, we show that DermFM-Zero's latent representations are interpretable: sparse autoencoders unsupervisedly disentangle clinically meaningful concepts that outperform predefined-vocabulary approaches and enable targeted suppression of artifact-induced biases, enhancing robustness without retraining. These findings demonstrate that a foundation model can provide effective, safe, and transparent zero-shot clinical decision support.

cs.CV↗

Full end-to-end diagnostic workflow automation of 3D OCT via foundation model-driven AI for retinal diseases

Optical coherence tomography (OCT) has revolutionized retinal disease diagnosis with its high-resolution and three-dimensional imaging nature, yet its full diagnostic automation in clinical practices remains constrained by multi-stage workflows and conventional single-slice single-task AI models. We present Full-process OCT-based Clinical Utility System (FOCUS), a foundation model-driven framework enabling end-to-end automation of 3D OCT retinal disease diagnosis. FOCUS sequentially performs image quality assessment with EfficientNetV2-S, followed by abnormality detection and multi-disease classification using a fine-tuned Vision Foundation Model. Crucially, FOCUS leverages a unified adaptive aggregation method to intelligently integrate 2D slices-level predictions into comprehensive 3D patient-level diagnosis. Trained and tested on 3,300 patients (40,672 slices), and externally validated on 1,345 patients (18,498 slices) across four different-tier centers and diverse OCT devices, FOCUS achieved high F1 scores for quality assessment (99.01%), abnormally detection (97.46%), and patient-level diagnosis (94.39%). Real-world validation across centers also showed stable performance (F1: 90.22%-95.24%). In human-machine comparisons, FOCUS matched expert performance in abnormality detection (F1: 95.47% vs 90.91%) and multi-disease diagnosis (F1: 93.49% vs 91.35%), while demonstrating better efficiency. FOCUS automates the image-to-diagnosis pipeline, representing a critical advance towards unmanned ophthalmology with a validated blueprint for autonomous screening to enhance population scale retinal care accessibility and efficiency.

cs.CV↗

Diff4MMLiTS: Advanced Multimodal Liver Tumor Segmentation via Diffusion-Based Image Synthesis and Alignment

Multimodal learning has been demonstrated to enhance performance across various clinical tasks, owing to the diverse perspectives offered by different modalities of data. However, existing multimodal segmentation methods rely on well-registered multimodal data, which is unrealistic for real-world clinical images, particularly for indistinct and diffuse regions such as liver tumors. In this paper, we introduce Diff4MMLiTS, a four-stage multimodal liver tumor segmentation pipeline: pre-registration of the target organs in multimodal CTs; dilation of the annotated modality's mask and followed by its use in inpainting to obtain multimodal normal CTs without tumors; synthesis of strictly aligned multimodal CTs with tumors using the latent diffusion model based on multimodal CT features and randomly generated tumor masks; and finally, training the segmentation model, thus eliminating the need for strictly aligned multimodal data. Extensive experiments on public and internal datasets demonstrate the superiority of Diff4MMLiTS over other state-of-the-art multimodal segmentation methods.

eess.IV↗

FUPareto: Bridging the Forgetting-Utility Gap in Federated Unlearning via Pareto Augmented Optimization

Federated Unlearning (FU) aims to efficiently remove the influence of specific client data from a federated model while preserving utility for the remaining clients. However, three key challenges remain: (1) existing unlearning objectives often compromise model utility or increase vulnerability to Membership Inference Attacks (MIA); (2) there is a persistent conflict between forgetting and utility, where further unlearning inevitably harms retained performance; and (3) support for concurrent multi-client unlearning is poor, as gradient conflicts among clients degrade the quality of forgetting. To address these issues, we propose FUPareto, an efficient unlearning framework via Pareto-augmented optimization. We first introduce the Minimum Boundary Shift (MBS) Loss, which enforces unlearning by suppressing the target class logit below the highest non-target class logit; this can improve the unlearning efficiency and mitigate MIA risks. During the unlearning process, FUPareto performs Pareto improvement steps to preserve model utility and executes Pareto expansion to guarantee forgetting. Specifically, during Pareto expansion, the framework integrates a Null-Space Projected Multiple Gradient Descent Algorithm (MGDA) to decouple gradient conflicts. This enables effective, fair, and concurrent unlearning for multiple clients while minimizing utility degradation. Extensive experiments across diverse scenarios demonstrate that FUPareto consistently outperforms state-of-the-art FU methods in both unlearning efficacy and retained utility.

cs.LG↗

A General Model for Retinal Segmentation and Quantification

Retinal imaging is fast, non-invasive, and widely available, offering quantifiable structural and vascular signals for ophthalmic and systemic health assessment. This accessibility creates an opportunity to study how quantitative retinal phenotypes relate to ocular and systemic diseases. However, such analyses remain difficult at scale due to the limited availability of public multi-label datasets and the lack of a unified segmentation-to-quantification pipeline. We present RetSAM, a general retinal segmentation and quantification framework for fundus imaging. It delivers robust multi-target segmentation and standardized biomarker extraction, supporting downstream ophthalmologic studies and oculomics correlation analyses. Trained on over 200,000 fundus images, RetSAM supports three task categories and segments five anatomical structures, four retinal phenotypic patterns, and more than 20 distinct lesion types. It converts these segmentation results into over 30 standardized biomarkers that capture structural morphology, vascular geometry, and degenerative changes. Trained with a multi-stage strategy using both private and public fundus data, RetSAM achieves superior segmentation performance on 17 public datasets. It improves on prior best methods by 3.9 percentage points in DSC on average, with up to 15 percentage points on challenging multi-task benchmarks, and generalizes well across diverse populations, imaging devices, and clinical settings. The resulting biomarkers enable systematic correlation analyses across major ophthalmic diseases, including diabetic retinopathy, age-related macular degeneration, glaucoma, and pathologic myopia. Together, RetSAM transforms fundus images into standardized, interpretable quantitative phenotypes, enabling large-scale ophthalmic research and translation.

cs.CV↗

NLPrompt: Noise-Label Prompt Learning for Vision-Language Models

The emergence of vision-language foundation models, such as CLIP, has revolutionized image-text representation, enabling a broad range of applications via prompt learning. Despite its promise, real-world datasets often contain noisy labels that can degrade prompt learning performance. In this paper, we demonstrate that using mean absolute error (MAE) loss in prompt learning, named PromptMAE, significantly enhances robustness against noisy labels while maintaining high accuracy. Though MAE is straightforward and recognized for its robustness, it is rarely used in noisy-label learning due to its slow convergence and poor performance outside prompt learning scenarios. To elucidate the robustness of PromptMAE, we leverage feature learning theory to show that MAE can suppress the influence of noisy samples, thereby improving the signal-to-noise ratio and enhancing overall robustness. Additionally, we introduce PromptOT, a prompt-based optimal transport data purification method to enhance the robustness further. PromptOT employs text features in vision-language models as prototypes to construct an optimal transportation matrix. This matrix effectively partitions datasets into clean and noisy subsets, allowing for the application of cross-entropy loss to the clean subset and MAE loss to the noisy subset. Our Noise-Label Prompt Learning method, named NLPrompt, offers a simple and efficient approach that leverages the expressive representations and precise alignment capabilities of vision-language models for robust prompt learning. We validate NLPrompt through extensive experiments across various noise settings, demonstrating significant performance improvements.

cs.CV↗

Optimal Boost Design for Auto-bidding Mechanism with Publisher Quality Constraints

Online bidding serves as a fundamental information system in mobile ecosystems, facilitating real-time ad allocation across billions of devices while optimizing both platform performance and user experience through data-driven decision making. Improving ad allocation efficiency is a long-standing research problem, as it directly enhances the economic outcomes for all participants in advertising platforms. This paper investigates the design of optimal boost factors in online bidding while incorporating quality value (the impact of displayed ads on publishers' long-term benefits). To address the divergent interests on quality, we establish a three-party auction framework with a unified welfare metric of advertiser and publisher. Within this framework, we derive the theoretical efficiency lower bound for C-competitive boost in second-price single-slot auctions, then design a novel quality-involved Boosting (q-Boost) algorithm for computing the optimal boost factor. Experimental validation on Alibaba's public dataset (AuctionNet) demonstrates 2%-6% welfare improvements over conventional approaches, proving our method's effectiveness in real-world settings.

cs.GT↗

UniFS: Unified Multi-Contrast MRI Reconstruction via Frequency-Spatial Fusion

Recently, Multi-Contrast MR Reconstruction (MCMR) has emerged as a hot research topic that leverages high-quality auxiliary modalities to reconstruct undersampled target modalities of interest. However, existing methods often struggle to generalize across different k-space undersampling patterns, requiring the training of a separate model for each specific pattern, which limits their practical applicability. To address this challenge, we propose UniFS, a Unified Frequency-Spatial Fusion model designed to handle multiple k-space undersampling patterns for MCMR tasks without any need for retraining. UniFS integrates three key modules: a Cross-Modal Frequency Fusion module, an Adaptive Mask-Based Prompt Learning module, and a Dual-Branch Complementary Refinement module. These modules work together to extract domain-invariant features from diverse k-space undersampling patterns while dynamically adapt to their own variations. Another limitation of existing MCMR methods is their tendency to focus solely on spatial information while neglect frequency characteristics, or extract only shallow frequency features, thus failing to fully leverage complementary cross-modal frequency information. To relieve this issue, UniFS introduces an adaptive prompt-guided frequency fusion module for k-space learning, significantly enhancing the model's generalization performance. We evaluate our model on the BraTS and HCP datasets with various k-space undersampling patterns and acceleration factors, including previously unseen patterns, to comprehensively assess UniFS's generalizability. Experimental results across multiple scenarios demonstrate that UniFS achieves state-of-the-art performance. Our code is available at https://github.com/LIKP0/UniFS.

cs.CV↗

AniMer+: Unified Pose and Shape Estimation Across Mammalia and Aves via Family-Aware Transformer

In the era of foundation models, achieving a unified understanding of different dynamic objects through a single network has the potential to empower stronger spatial intelligence. Moreover, accurate estimation of animal pose and shape across diverse species is essential for quantitative analysis in biological research. However, this topic remains underexplored due to the limited network capacity of previous methods and the scarcity of comprehensive multi-species datasets. To address these limitations, we introduce AniMer+, an extended version of our scalable AniMer framework. In this paper, we focus on a unified approach for reconstructing mammals (mammalia) and birds (aves). A key innovation of AniMer+ is its high-capacity, family-aware Vision Transformer (ViT) incorporating a Mixture-of-Experts (MoE) design. Its architecture partitions network layers into taxa-specific components (for mammalia and aves) and taxa-shared components, enabling efficient learning of both distinct and common anatomical features within a single model. To overcome the critical shortage of 3D training data, especially for birds, we introduce a diffusion-based conditional image generation pipeline. This pipeline produces two large-scale synthetic datasets: CtrlAni3D for quadrupeds and CtrlAVES3D for birds. To note, CtrlAVES3D is the first large-scale, 3D-annotated dataset for birds, which is crucial for resolving single-view depth ambiguities. Trained on an aggregated collection of 41.3k mammalian and 12.4k avian images (combining real and synthetic data), our method demonstrates superior performance over existing approaches across a wide range of benchmarks, including the challenging out-of-domain Animal Kingdom dataset. Ablation studies confirm the effectiveness of both our novel network architecture and the generated synthetic datasets in enhancing real-world application performance.

cs.CV↗

The End of Manual Decoding: Towards Truly End-to-End Language Models

The "end-to-end" label for LLMs is a misnomer. In practice, they depend on a non-differentiable decoding process that requires laborious, hand-tuning of hyperparameters like temperature and top-p. This paper introduces AutoDeco, a novel architecture that enables truly "end-to-end" generation by learning to control its own decoding strategy. We augment the standard transformer with lightweight heads that, at each step, dynamically predict context-specific temperature and top-p values alongside the next-token logits. This approach transforms decoding into a parametric, token-level process, allowing the model to self-regulate its sampling strategy within a single forward pass. Through extensive experiments on eight benchmarks, we demonstrate that AutoDeco not only significantly outperforms default decoding strategies but also achieves performance comparable to an oracle-tuned baseline derived from "hacking the test set"-a practical upper bound for any static method. Crucially, we uncover an emergent capability for instruction-based decoding control: the model learns to interpret natural language commands (e.g., "generate with low randomness") and adjusts its predicted temperature and top-p on a token-by-token basis, opening a new paradigm for steerable and interactive LLM decoding.

cs.CL↗

DynaCausal: Dynamic Causality-Aware Root Cause Analysis for Distributed Microservices

Cloud-native microservices enable rapid iteration and scalable deployment but also create complex, fast-evolving dependencies that challenge reliable diagnosis. Existing root cause analysis (RCA) approaches, even with multi-modal fusion of logs, traces, and metrics, remain limited in capturing dynamic behaviors and shifting service relationships. Three critical challenges persist: (i) inadequate modeling of cascading fault propagation, (ii) vulnerability to noise interference and concept drift in normal service behavior, and (iii) over-reliance on service deviation intensity that obscures true root causes. To address these challenges, we propose DynaCausal, a dynamic causality-aware framework for RCA in distributed microservice systems. DynaCausal unifies multi-modal dynamic signals to capture time-varying spatio-temporal dependencies through interaction-aware representation learning. It further introduces a dynamic contrastive mechanism to disentangle true fault indicators from contextual noise and adopts a causal-prioritized pairwise ranking objective to explicitly optimize causal attribution. Comprehensive evaluations on public benchmarks demonstrate that DynaCausal consistently surpasses state-of-the-art methods, attaining an average AC@1 of 0.63 with absolute gains from 0.25 to 0.46, and delivering both accurate and interpretable diagnoses in highly dynamic microservice environments.

cs.SE↗

CLEANet: Robust and Efficient Anomaly Detection in Contaminated Multivariate Time Series

Multivariate time series (MTS) anomaly detection is essential for maintaining the reliability of industrial systems, yet real-world deployment is hindered by two critical challenges: training data contamination (noises and hidden anomalies) and inefficient model inference. Existing unsupervised methods assume clean training data, but contamination distorts learned patterns and degrades detection accuracy. Meanwhile, complex deep models often overfit to contamination and suffer from high latency, limiting practical use. To address these challenges, we propose CLEANet, a robust and efficient anomaly detection framework in contaminated multivariate time series. CLEANet introduces a Contamination-Resilient Training Framework (CRTF) that mitigates the impact of corrupted samples through an adaptive reconstruction weighting strategy combined with clustering-guided contrastive learning, thereby enhancing robustness. To further avoid overfitting on contaminated data and improve computational efficiency, we design a lightweight conjugate MLP that disentangles temporal and cross-feature dependencies. Across five public datasets, CLEANet achieves up to 73.04% higher F1 and 81.28% lower runtime compared with ten state-of-the-art baselines. Furthermore, integrating CRTF into three advanced models yields an average 5.35% F1 gain, confirming its strong generalizability.

cs.LG↗