arXiv subjects

Xin Tian

Publications and source records attributed to Xin Tian.

At least 37 records · Page 2Linked to original sources

arXiv2024

The Quest for Early Detection of Retinal Disease: 3D CycleGAN-based Translation of Optical Coherence Tomography into Confocal Microscopy

Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, offering distinct advantages and limitations. In vivo OCT offers rapid, non-invasive imaging but can suffer from clarity issues and motion artifacts, while ex vivo confocal microscopy, providing high-resolution, cellular-detailed color images, is invasive and raises ethical concerns. To bridge the benefits of both modalities, we propose a novel framework based on unsupervised 3D CycleGAN for translating unpaired in vivo OCT to ex vivo confocal microscopy images. This marks the first attempt to exploit the inherent 3D information of OCT and translate it into the rich, detailed color domain of confocal microscopy. We also introduce a unique dataset, OCT2Confocal, comprising mouse OCT and confocal retinal images, facilitating the development of and establishing a benchmark for cross-modal image translation research. Our model has been evaluated both quantitatively and qualitatively, achieving Fréchet Inception Distance (FID) scores of 0.766 and Kernel Inception Distance (KID) scores as low as 0.153, and leading subjective Mean Opinion Scores (MOS). Our model demonstrated superior image fidelity and quality with limited data over existing methods. Our approach effectively synthesizes color information from 3D confocal images, closely approximating target outcomes and suggesting enhanced potential for diagnostic and monitoring applications in ophthalmology.

eess.IV↗

arXiv2024

Hybrid Spatial-spectral Neural Network for Hyperspectral Image Denoising

Hyperspectral image (HSI) denoising is an essential procedure for HSI applications. Unfortunately, the existing Transformer-based methods mainly focus on non-local modeling, neglecting the importance of locality in image denoising. Moreover, deep learning methods employ complex spectral learning mechanisms, thus introducing large computation costs. To address these problems, we propose a hybrid spatial-spectral denoising network (HSSD), in which we design a novel hybrid dual-path network inspired by CNN and Transformer characteristics, leading to capturing both local and non-local spatial details while suppressing noise efficiently. Furthermore, to reduce computational complexity, we adopt a simple but effective decoupling strategy that disentangles the learning of space and spectral channels, where multilayer perception with few parameters is utilized to learn the global correlations among spectra. The synthetic and real experiments demonstrate that our proposed method outperforms state-of-the-art methods on spatial and spectral reconstruction. The code and details are available on https://github.com/HLImg/HSSD.

eess.IV↗

arXiv2024

TaGAT: Topology-Aware Graph Attention Network For Multi-modal Retinal Image Fusion

In the realm of medical image fusion, integrating information from various modalities is crucial for improving diagnostics and treatment planning, especially in retinal health, where the important features exhibit differently in different imaging modalities. Existing deep learning-based approaches insufficiently focus on retinal image fusion, and thus fail to preserve enough anatomical structure and fine vessel details in retinal image fusion. To address this, we propose the Topology-Aware Graph Attention Network (TaGAT) for multi-modal retinal image fusion, leveraging a novel Topology-Aware Encoder (TAE) with Graph Attention Networks (GAT) to effectively enhance spatial features with retinal vasculature's graph topology across modalities. The TAE encodes the base and detail features, extracted via a Long-short Range (LSR) encoder from retinal images, into the graph extracted from the retinal vessel. Within the TAE, the GAT-based Graph Information Update (GIU) block dynamically refines and aggregates the node features to generate topology-aware graph features. The updated graph features with base and detail features are combined and decoded as a fused image. Our model outperforms state-of-the-art methods in Fluorescein Fundus Angiography (FFA) with Color Fundus (CF) and Optical Coherence Tomography (OCT) with confocal microscopy retinal image fusion. The source code can be accessed via https://github.com/xintian-99/TaGAT.

eess.IV↗

arXiv2024

A Canonical Data Transformation for Achieving Inter- and Within-group Fairness

Increases in the deployment of machine learning algorithms for applications that deal with sensitive data have brought attention to the issue of fairness in machine learning. Many works have been devoted to applications that require different demographic groups to be treated fairly. However, algorithms that aim to satisfy inter-group fairness (also called group fairness) may inadvertently treat individuals within the same demographic group unfairly. To address this issue, we introduce a formal definition of within-group fairness that maintains fairness among individuals from within the same group. We propose a pre-processing framework to meet both inter- and within-group fairness criteria with little compromise in accuracy. The framework maps the feature vectors of members from different groups to an inter-group-fair canonical domain before feeding them into a scoring function. The mapping is constructed to preserve the relative relationship between the scores obtained from the unprocessed feature vectors of individuals from the same demographic group, guaranteeing within-group fairness. We apply this framework to the COMPAS risk assessment and Law School datasets and compare its performance in achieving inter-group and within-group fairness to two regularization-based methods.

cs.LG↗

arXiv2024

Inferring ECG from PPG for Continuous Cardiac Monitoring Using Lightweight Neural Network

This paper presents a computational solution that enables continuous cardiac monitoring through cross-modality inference of electrocardiogram (ECG). While some smartwatches now allow users to obtain a 30-second ECG test by tapping a built-in bio-sensor, these short-term ECG tests often miss intermittent and asymptomatic abnormalities of cardiac functions. It is also infeasible to expect persistently active user participation for long-term continuous cardiac monitoring in order to capture these and other types of cardiac abnormalities. To alleviate the need for continuous user attention and active participation, we design a lightweight neural network that infers ECG from the photoplethysmogram (PPG) signal sensed at the skin surface by a wearable optical sensor. We also develop a diagnosis-oriented training strategy to enable the neural network to capture the pathological features of ECG, aiming to increase the utility of reconstructed ECG signals for screening cardiovascular diseases (CVDs). We also leverage model interpretation to obtain insights from data-driven models, for example, to reveal some associations between CVDs and ECG/PPG and to demonstrate how the neural network copes with motion artifacts in the ambulatory application. The experimental results on three datasets demonstrate the feasibility of inferring ECG from PPG, achieving a high fidelity of ECG reconstruction with only about 40K parameters.

eess.SP↗

arXiv2024

OCT2Confocal: 3D CycleGAN based Translation of Retinal OCT Images to Confocal Microscopy

Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, each presenting unique benefits and limitations. In-vivo OCT offers rapid, non-invasive imaging but can be hampered by clarity issues and motion artifacts. Ex-vivo confocal microscopy provides high-resolution, cellular detailed color images but is invasive and poses ethical concerns and potential tissue damage. To bridge these modalities, we developed a 3D CycleGAN framework for unsupervised translation of in-vivo OCT to ex-vivo confocal microscopy images. Applied to our OCT2Confocal dataset, this framework effectively translates between 3D medical data domains, capturing vascular, textural, and cellular details with precision. This marks the first attempt to exploit the inherent 3D information of OCT and translate it into the rich, detailed color domain of confocal microscopy. Assessed through quantitative and qualitative evaluations, the 3D CycleGAN framework demonstrates commendable image fidelity and quality, outperforming existing methods despite the constraints of limited data. This non-invasive generation of retinal confocal images has the potential to further enhance diagnostic and monitoring capabilities in ophthalmology. Our source code and OCT2Confocal dataset are available at https://github.com/xintian-99/OCT2Confocal.

eess.IV↗

arXiv2023

Query Enhanced Knowledge-Intensive Conversation via Unsupervised Joint Modeling

In this paper, we propose an unsupervised query enhanced approach for knowledge-intensive conversations, namely QKConv. There are three modules in QKConv: a query generator, an off-the-shelf knowledge selector, and a response generator. QKConv is optimized through joint training, which produces the response by exploring multiple candidate queries and leveraging corresponding selected knowledge. The joint training solely relies on the dialogue context and target response, getting exempt from extra query annotations or knowledge provenances. To evaluate the effectiveness of the proposed QKConv, we conduct experiments on three representative knowledge-intensive conversation datasets: conversational question-answering, task-oriented dialogue, and knowledge-grounded conversation. Experimental results reveal that QKConv performs better than all unsupervised methods across three datasets and achieves competitive performance compared to supervised methods.

cs.CL↗

arXiv2022

PLATO-XL: Exploring the Large-scale Pre-training of Dialogue Generation

To explore the limit of dialogue generation pre-training, we present the models of PLATO-XL with up to 11 billion parameters, trained on both Chinese and English social media conversations. To train such large models, we adopt the architecture of unified transformer with high computation and parameter efficiency. In addition, we carry out multi-party aware pre-training to better distinguish the characteristic information in social media conversations. With such designs, PLATO-XL successfully achieves superior performances as compared to other approaches in both Chinese and English chitchat. We further explore the capacity of PLATO-XL on other conversational tasks, such as knowledge grounded dialogue and task-oriented conversation. The experimental results indicate that PLATO-XL obtains state-of-the-art results across multiple conversational tasks, verifying its potential as a foundation model of conversational AI.

cs.CL↗

arXiv2022

Q-TOD: A Query-driven Task-oriented Dialogue System

Existing pipelined task-oriented dialogue systems usually have difficulties adapting to unseen domains, whereas end-to-end systems are plagued by large-scale knowledge bases in practice. In this paper, we introduce a novel query-driven task-oriented dialogue system, namely Q-TOD. The essential information from the dialogue context is extracted into a query, which is further employed to retrieve relevant knowledge records for response generation. Firstly, as the query is in the form of natural language and not confined to the schema of the knowledge base, the issue of domain adaption is alleviated remarkably in Q-TOD. Secondly, as the query enables the decoupling of knowledge retrieval from the generation, Q-TOD gets rid of the issue of knowledge base scalability. To evaluate the effectiveness of the proposed Q-TOD, we collect query annotations for three publicly available task-oriented dialogue datasets. Comprehensive experiments verify that Q-TOD outperforms strong baselines and establishes a new state-of-the-art performance on these datasets.

cs.CL↗

arXiv2022

High-Capacity Rechargeable $Li/Cl_2$ Batteries with Graphite Positive Electrodes

Developing new types of high-capacity and high-energy density rechargeable battery is important to future generations of consumer electronics, electric vehicles, and mass energy storage applications. Recently we reported ~ 3.5 V sodium/chlorine $(Na/Cl_2)$ and lithium/chlorine $(Li/Cl_2)$ batteries with up to 1200 mAh $g^{-1}$ reversible capacity, using either a Na or Li metal as the negative electrode, an amorphous carbon nanosphere (aCNS) as the positive electrode, and aluminum chloride $(AlCl_3)$ dissolved in thionyl chloride $(SOCl_2)$ with fluoride-based additives as the electrolyte. The high surface area and large pore volume of aCNS in the positive electrode facilitated NaCl or LiCl deposition and trapping of $Cl_2$ for reversible $NaCl/Cl_2$ or $LiCl/Cl_2$ redox reactions and battery discharge/charge cycling. Here we report an initially low surface area/porosity graphite (DGr) material as the positive electrode in a $Li/Cl_2$ battery, attaining high battery performance after activation in carbon dioxide $(CO_2)$ at 1000 °C (DGr_ac) with the first discharge capacity ~ 1910 mAh $g^{-1}$ and a cycling capacity up to 1200 mAh $g^{-1}$. Ex situ Raman spectroscopy and X-ray diffraction (XRD) revealed the evolution of graphite over battery cycling, including intercalation/de-intercalation and exfoliation that generated sufficient pores for hosting $LiCl/Cl_2$ redox. This work opens up widely available, low-cost graphitic materials for high-capacity alkali metal/$Cl_2$ batteries. Lastly, we employed mass spectrometry to probe the $Cl_2$ trapped in the graphitic positive electrode, shedding light into the $Li/Cl_2$ battery operation.

physics.app-ph↗

arXiv2022

Crack patterns of drying dense bacterial suspensions

Drying of bacterial suspensions is frequently encountered in a plethora of natural and engineering processes. However, the evaporation-driven mechanical instabilities of dense consolidating bacterial suspensions have not been explored heretofore. Here, we report the formation of two different crack patterns of drying suspensions of \textit{Escherichia coli} (\textit{E. coli}) with distinct motile behaviors. Circular cracks are observed for wild-type \textit{E. coli} with active swimming, whereas spiral-like cracks form for immotile bacteria. Using the elastic fracture mechanics and the poroelastic theory, we show that the formation of the circular cracks is determined by the tensile nature of the radial drying stress once the cracks are initiated by the local order structure of bacteria due to their collective swimming. Our study demonstrates the link between the microscopic swimming behaviors of individual bacteria and the mechanical instabilities and macroscopic pattern formation of drying bacterial films. The results shed light on the dynamics of active matter in a drying process and provide useful information for understanding various biological processes associated with drying bacterial suspensions.

cond-mat.soft↗

arXiv2022

Bi-directional Object-context Prioritization Learning for Saliency Ranking

The saliency ranking task is recently proposed to study the visual behavior that humans would typically shift their attention over different objects of a scene based on their degrees of saliency. Existing approaches focus on learning either object-object or object-scene relations. Such a strategy follows the idea of object-based attention in Psychology, but it tends to favor those objects with strong semantics (e.g., humans), resulting in unrealistic saliency ranking. We observe that spatial attention works concurrently with object-based attention in the human visual recognition system. During the recognition process, the human spatial attention mechanism would move, engage, and disengage from region to region (i.e., context to context). This inspires us to model the region-level interactions, in addition to the object-level reasoning, for saliency ranking. To this end, we propose a novel bi-directional method to unify spatial attention and object-based attention for saliency ranking. Our model includes two novel modules: (1) a selective object saliency (SOS) module that models objectbased attention via inferring the semantic representation of the salient object, and (2) an object-context-object relation (OCOR) module that allocates saliency ranks to objects by jointly modeling the object-context and context-object interactions of the salient objects. Extensive experiments show that our approach outperforms existing state-of-theart methods. Our code and pretrained model are available at https://github.com/GrassBro/OCOR.

cs.CV↗

arXiv2022

Optimal Transport-based Graph Matching for 3D retinal OCT image registration

Registration of longitudinal optical coherence tomography (OCT) images assists disease monitoring and is essential in image fusion applications. Mouse retinal OCT images are often collected for longitudinal study of eye disease models such as uveitis, but their quality is often poor compared with human imaging. This paper presents a novel but efficient framework involving an optimal transport based graph matching (OT-GM) method for 3D mouse OCT image registration. We first perform registration of fundus-like images obtained by projecting all b-scans of a volume on a plane orthogonal to them, hereafter referred to as the x-y plane. We introduce Adaptive Weighted Vessel Graph Descriptors (AWVGD) and 3D Cube Descriptors (CD) to identify the correspondence between nodes of graphs extracted from segmented vessels within the OCT projection images. The AWVGD comprises scaling, translation and rotation, which are computationally efficient, whereas CD exploits 3D spatial and frequency domain information. The OT-GM method subsequently performs the correct alignment in the x-y plane. Finally, registration along the direction orthogonal to the x-y plane (the z-direction) is guided by the segmentation of two important anatomical features peculiar to mouse b-scans, the Internal Limiting Membrane (ILM) and the hyaloid remnant (HR). Both subjective and objective evaluation results demonstrate that our framework outperforms other well-established methods on mouse OCT images within a reasonable execution time.

cs.CV↗

arXiv2021

TOD-DA: Towards Boosting the Robustness of Task-oriented Dialogue Modeling on Spoken Conversations

Task-oriented dialogue systems have been plagued by the difficulties of obtaining large-scale and high-quality annotated conversations. Furthermore, most of the publicly available datasets only include written conversations, which are insufficient to reflect actual human behaviors in practical spoken dialogue systems. In this paper, we propose Task-oriented Dialogue Data Augmentation (TOD-DA), a novel model-agnostic data augmentation paradigm to boost the robustness of task-oriented dialogue modeling on spoken conversations. The TOD-DA consists of two modules: 1) Dialogue Enrichment to expand training data on task-oriented conversations for easing data sparsity and 2) Spoken Conversation Simulator to imitate oral style expressions and speech recognition errors in diverse granularities for bridging the gap between written and spoken conversations. With such designs, our approach ranked first in both tasks of DSTC10 Track2, a benchmark for task-oriented dialogue modeling on spoken conversations, demonstrating the superiority and effectiveness of our proposed TOD-DA.

cs.CL↗

arXiv2021

Learning to Detect Instance-level Salient Objects Using Complementary Image Labels

Existing salient instance detection (SID) methods typically learn from pixel-level annotated datasets. In this paper, we present the first weakly-supervised approach to the SID problem. Although weak supervision has been considered in general saliency detection, it is mainly based on using class labels for object localization. However, it is non-trivial to use only class labels to learn instance-aware saliency information, as salient instances with high semantic affinities may not be easily separated by the labels. As the subitizing information provides an instant judgement on the number of salient items, it is naturally related to detecting salient instances and may help separate instances of the same class while grouping different parts of the same instance. Inspired by this observation, we propose to use class and subitizing labels as weak supervision for the SID problem. We propose a novel weakly-supervised network with three branches: a Saliency Detection Branch leveraging class consistency information to locate candidate objects; a Boundary Detection Branch exploiting class discrepancy information to delineate object boundaries; and a Centroid Detection Branch using subitizing information to detect salient instance centroids. This complementary information is then fused to produce a salient instance map. To facilitate the learning process, we further propose a progressive training scheme to reduce label noise and the corresponding noise learned by the model, via reciprocating the model with progressive salient instance prediction and model refreshing. Our extensive evaluations show that the proposed method plays favorably against carefully designed baseline methods adapted from related tasks.

cs.CV↗

arXiv2021

Amendable Generation for Dialogue State Tracking

In task-oriented dialogue systems, recent dialogue state tracking methods tend to perform one-pass generation of the dialogue state based on the previous dialogue state. The mistakes of these models made at the current turn are prone to be carried over to the next turn, causing error propagation. In this paper, we propose a novel Amendable Generation for Dialogue State Tracking (AG-DST), which contains a two-pass generation process: (1) generating a primitive dialogue state based on the dialogue of the current turn and the previous dialogue state, and (2) amending the primitive dialogue state from the first pass. With the additional amending generation pass, our model is tasked to learn more robust dialogue state tracking by amending the errors that still exist in the primitive dialogue state, which plays the role of reviser in the double-checking process and alleviates unnecessary error propagation. Experimental results show that AG-DST significantly outperforms previous works in two active DST datasets (MultiWOZ 2.2 and WOZ 2.0), achieving new state-of-the-art performances.

cs.CL↗

arXiv2021

FewCLUE: A Chinese Few-shot Learning Evaluation Benchmark

Pretrained Language Models (PLMs) have achieved tremendous success in natural language understanding tasks. While different learning schemes -- fine-tuning, zero-shot, and few-shot learning -- have been widely explored and compared for languages such as English, there is comparatively little work in Chinese to fairly and comprehensively evaluate and compare these methods and thus hinders cumulative progress. In this paper, we introduce the Chinese Few-shot Learning Evaluation Benchmark (FewCLUE), the first comprehensive few-shot evaluation benchmark in Chinese. It includes nine tasks, ranging from single-sentence and sentence-pair classification tasks to machine reading comprehension tasks. We systematically evaluate five state-of-the-art (SOTA) few-shot learning methods (including PET, ADAPET, LM-BFF, P-tuning and EFL), and compare their performance with fine-tuning and zero-shot learning schemes on the newly constructed FewCLUE benchmark. Experimental results reveal that: 1) The effect of different few-shot learning methods is sensitive to the pre-trained model to which the methods are applied; 2) PET and P-tuning achieve the best overall performance with RoBERTa and ERNIE respectively. Our benchmark is used in the few-shot learning contest of NLPCC 2021. In addition, we provide a user-friendly toolkit, as well as an online leaderboard to help facilitate further progress on Chinese few-shot learning. We provide a baseline performance on different learning methods, a reference for future research.

cs.CL↗

arXiv2021

A Unified Pre-training Framework for Conversational AI

In this work, we explore the application of PLATO-2 on various dialogue systems, including open-domain conversation, knowledge grounded dialogue, and task-oriented conversation. PLATO-2 is initially designed as an open-domain chatbot, trained via two-stage curriculum learning. In the first stage, a coarse-grained response generation model is learned to fit the simplified one-to-one mapping relationship. This model is applied to the task-oriented conversation, given that the semantic mappings tend to be deterministic in task completion. In the second stage, another fine-grained generation model and an evaluation model are further learned for diverse response generation and coherence estimation, respectively. With superior capability on capturing one-to-many mapping, such models are suitable for the open-domain conversation and knowledge grounded dialogue. For the comprehensive evaluation of PLATO-2, we have participated in multiple tasks of DSTC9, including interactive evaluation of open-domain conversation (Track3-task2), static evaluation of knowledge grounded dialogue (Track3-task1), and end-to-end task-oriented conversation (Track2-task1). PLATO-2 has obtained the 1st place in all three tasks, verifying its effectiveness as a unified framework for various dialogue systems.

cs.CL↗