arXiv subjects

Yang Ni

Publications and source records attributed to Yang Ni.

At least 19 recordsLinked to original sources

arXiv2026

AudioLens: Multi-Perspective Speech Clustering with Reasoning Audio-Language Models

Audio clustering is a fundamental task for organizing rapidly growing speech collections, supporting applications such as conversational analysis and speech-driven discovery. However, existing methods rely on fixed acoustic similarity metrics or ASR-based text pipelines, limiting their ability to reorganize the same audio collection under different user-specified perspectives, especially when clustering depends on both linguistic and paralinguistic cues. We introduce audio multi-perspective clustering, where a model directly partitions speech recordings according to a natural-language perspective while inferring both the number of clusters and their assignments. To study this setting, we construct AudioLens-Bench, a benchmark spanning multiple application domains and evaluating both in-perspective and cross-perspective generalization. We further propose AudioLens-R1, an end-to-end large audio-language model trained with reasoning distillation and preference optimization. Experiments show that AudioLens-R1 consistently outperforms all baselines, improving overall ARI by 12.99 points and V-measure by 11.62 points. These results demonstrate the promise of native audio-language models for flexible, perspective-conditioned structure discovery over speech collections.

cs.SD↗

arXiv2026

Distributional Determinantal Point Process for Repulsive Clustering of Distributions

We introduce the distributional determinantal point process (dDPP) as a novel repulsive point process whose atoms are probability distributions rather than points in a real space. The dDPP is constructed via an L-ensemble with a sliced Wasserstein (SW) kernel between distributions. We show its validity as a well-defined point process. In the discrete setting, we derive concentration results for plug-in estimators of the L-ensemble, the correlation kernel, and their determinants given i.i.d. samples from the distributional atoms. Leveraging this framework, we propose a distribution-valued random partition model by way of a repulsive generalized Bayesian mixture model. The model places a dDPP prior over the atoms of the mixing measure and defines a generalized likelihood based on SW distance. To summarize posterior inference, we develop a decision-theoretic approach to report a point estimate of the mixing measure as a Bayes rule under a hierarchical optimal transport utility function. The latter is a natural choice given that the mixing measure is itself a distribution over distributions. We use the proposed framework for inference with single-cell gene expression data and human epilepsy data, producing interpretable and well-separated clusters that reflect meaningful structure in the data.

stat.ME↗

arXiv2026

Modeling the Evolution of Protoplanetary Disks: Two Pathways from Gravitational Instability to MHD Wind-Driven Accretion

The global evolution of protoplanetary disks sets the initial conditions for planet formation. However, most models focus on individual evolutionary phases, with idealized initial conditions and oversimplified prescriptions for angular momentum transport and thermodynamics. We present a more realistic semi-two-dimensional ($1+1$D) model incorporating gravitational instability (GI), magnetohydrodynamic (MHD) winds, magneto-rotational instability (MRI), stellar irradiation, self-shadowing, and radiation transport. The radial distribution of large-scale magnetic flux drives two different pathways of disk evolution. When the vertical field is spatially uniform, a puffed-up, MRI-heated inner rim shadows the disk beyond it, sustaining a massive, gravitationally unstable region for $\sim 1$ Myr and, for several Myr, a compact ($\lesssim 10$ AU), cold ($\sim10$ K), low-turbulence ($\alpha_\mathrm{SS}\sim10^{-4}$), high-density ($\Sigma\gtrsim300\,\mathrm{g\,cm^{-2}}$), optically thick reservoir, so that the disk mass inferred from mm-continuum emission can be greatly underestimated. When the field instead scales with midplane gas pressure, it drives stronger transport in the inner disk and eventually strips the shadow, leaving an extended, flared disk whose observable mass closely traces the true mass. Our results connect GI-dominated Class~0/I disks to MHD wind-driven Class~II disks, and point to three broader conclusions: (i) disk physics is strongly inhomogeneous in space and time, so constant-$\alpha$ treatments miss essential physics; (ii) thermodynamics plays an active role, with self-shadowing simultaneously preserving GI and weakening MHD winds; and (iii) the distribution of large-scale magnetic flux is the key uncertainty, closely linked to whether the shadow is maintained. The two pathways align, respectively, with observations of compact, shadowed disks and extended, irradiated disks.

astro-ph.EP↗

arXiv2026

Structure Learning for Directed Trees with Zero-Inflated Compositional Nodes

Compositional data, which are vectors of proportions constrained to the probability simplex, arise frequently in modern scientific applications, including microbiome relative abundances across body sites and cell-type mixture weights derived from single-cell genomics. While regression methods for compositional data are well developed, no existing graphical model framework addresses the problem of learning conditional dependence structures among multiple compositional vectors. This paper introduces a novel framework for directed tree structure learning over compositional nodes. We employ the Kullback-Leibler divergence as the scoring function and model the conditional expectation of each child composition as a mixture of a baseline composition and a parent-driven component parameterized by a column-stochastic transition matrix. This formulation respects the simplex geometry, handles zero-inflated compositions gracefully, and, combined with a non-degeneracy condition on the transition matrix, ensures identifiability of edge directions from observational data. We prove consistency of structure recovery and derive finite-sample guarantees that characterize the required sample size in terms of the signal gap, node dimension, and penalty level. The efficacy of our approach is demonstrated through simulations and applications to multi-site microbiome data and single-cell data, yielding interpretable directed structures that align with known biological mechanisms.

stat.ME↗

arXiv2026

MR-CCC: Bayesian Mendelian Randomization for Causal Cell--Cell Communication

Cell--cell communication (CCC) is commonly inferred from ligand--receptor co-expression, an associational paradigm that cannot distinguish causal signaling from shared regulation or confounding. We propose MR-CCC, a Bayesian Mendelian randomization framework that uses cis-eQTLs as instruments for ligand and receptor expression and explicitly models receptor-modulated ligand effects through an interaction term, so the causal effect of a ligand can vary with receptor abundance. A spike--and--slab prior yields posterior inclusion probabilities quantifying evidence for causal signaling, and an efficient Gibbs sampler provides scalable inference. Benchmarked against naive regression, MVMR, and MR-BMA, MR-CCC controls false discoveries under confounding while retaining high power, and uniquely estimates both the ligand main and receptor-modulated interaction effects. Applied to the OneK1K NK cells $\to$ monocytes axis, MR-CCC identifies eight discoveries across GABA, interferon, interleukin, and prostaglandin signaling, including a stoichiometry-dependent dissociation of the two IL-18 receptor chains and co-discovery of both obligate IFN-$\gamma$ receptor subunits.

stat.ME↗

arXiv2026

JASPER: Joint Bayesian Analysis of Spatial Expression via Regression

Spatially resolved transcriptomics is a fast-developing set of technologies that enables the measurement of localized gene expression across spatial locations in a sample. Detecting spatially varying genes is critical for analyzing such data, yet existing methods often fail to account for inter-gene correlations, leading to inflated false positive and false negative rates. Additionally, most prominent methods rely on predefined spatial covariance kernels, making them sensitive to the complexity of spatial expression patterns. Motivated by a human breast cancer dataset, we address these limitations in existing literature through JASPER (Joint Bayesian Analysis of SPatial Expression via Regression), a Bayesian framework that jointly models spatial expression patterns across multiple genes using a spatial basis function regression approach. We demonstrate the superior performance of JASPER compared to existing methods in several real-world spatial transcriptomic datasets and supporting simulation experiments. JASPER identifies genes with stronger spatial correlation and greater biological relevance, as validated by overlap comparison, enrichment analysis, and pathway analysis using independent biological databases. Our results highlight the ability of JASPER to improve the statistical and biological interpretability of spatial transcriptomics data, making it a powerful tool for uncovering spatial gene expression patterns in complex biological systems.

stat.AP↗

arXiv2026

Nested Atoms Model with Application to Clustering Big Population-Scale Single-Cell Data

We consider the problem of clustering nested or hierarchical data, where observations are grouped and there are both group-level and observation-level variables. In our motivating OneK1K dataset, observations consist of single-cell RNA-sequencing (scRNA-seq) data from 982 individuals (groups), totaling 1.27 million cells (observations), along with individual-specific genotype data. This type of data would enable the identification of cell types and the investigation of how genetic variations among individuals influence differences in cell-type profiles. Our goal, therefore, is to jointly cluster cells and individuals to capture the heterogeneity across both levels using cell-specific gene expressions as well as individual-specific genotypes. However, existing grouped clustering methods do not incorporate group-level variables, thereby limiting their ability to capture the heterogeneity of genotypes in our motivating application. To address this, we propose the Nested Atoms Model (NAM), a new Bayesian nonparametric approach that enables the desired two-layered clustering, accounting for both group-level and observation-level variables. To scale NAM for high-dimensional data, we develop a fast variational Bayesian inference algorithm. Simulations show that NAM outperforms existing methods that ignore group-level variables. Applied to the OneK1K dataset, NAM identifies clusters of genetically similar individuals with homogeneous cell-type profiles. The resulting cell clusters align with known immune cell types based on differential gene expression, underscoring the ability of NAM to capture nested heterogeneity and provide biologically meaningful insights.

stat.ME↗

arXiv2026

Vertical Consensus Inference for High-Dimensional Random Partition

We review recently proposed Bayesian approaches for clustering high-dimensional data. After identifying the main limitations of available approaches, we introduce an alternative framework based on vertical consensus inference (VCI) to mitigate the curse of dimensionality in high-dimensional Bayesian clustering. VCI builds on the idea of consensus Monte Carlo by dividing the data into multiple shards (smaller subsets of variables), performing posterior inference on each shard, and then combining the shard-level posteriors to obtain a consensus posterior. The key distinction is that VCI splits the data vertically, producing vertical shards that retain the same number of observations but have lower dimensionality. We use an entropic regularized Wasserstein barycenter to define a consensus posterior. The shard-specific barycenter weights are constructed to favor shards that provide meaningful partitions, distinct from a trivial single cluster or all singleton clusters, favoring balanced cluster sizes and precise shard-specific posterior random partitions. We show that VCI can be interpreted as a variational approximation to the posterior under a hierarchical model with a generalized Bayes prior. For relatively low-dimensional problems, experiments suggest that VCI closely approximates inference based on clustering the entire multivariate data. For high-dimensional data and in the presence of many noninformative dimensions, VCI introduces a new framework for model-based and principled inference on random partitions. Although our focus here is on random partitions, VCI can be applied to any dimension-independent parameters and serves as a bridge to emerging areas in statistics such as consensus Monte Carlo, optimal transport, variational inference, and generalized Bayes.

stat.ME↗

arXiv2026

TRINE: A Token-Aware, Runtime-Adaptive FPGA Inference Engine for Multimodal AI

Multimodal stacks that mix ViTs, CNNs, GNNs, and transformer NLP strain embedded platforms because their compute/memory patterns diverge and hard real-time targets leave little slack. TRINE is a single-bitstream FPGA accelerator and compiler that executes end-to-end multimodal inference without reconfiguration. Layers are unified as DDMM/SDDMM/SpMM and mapped to a mode-switchable engine that toggles at runtime among weight/output-stationary systolic, 1xCS SIMD, and a routable adder tree (RADT) on a shared PE array. A width-matched, two-stage top-k unit enables in-stream token pruning, while dependency-aware layer offloading (DALO) overlaps independent kernels across reconfigurable processing units to sustain utilization. Evaluated on Alveo U50 and ZCU104, TRINE reduces latency by up to 22.57x vs. RTX 4090 and 6.86x vs. Jetson Orin Nano at 20-21 W; token pruning alone yields up to 7.8x on ViT-heavy pipelines, and DALO contributes up to 79% throughput improvement. With int8 quantization, accuracy drops remain <2.5% across representative tasks, delivering state-of-the-art latency and energy efficiency for unified vision, language, and graph workloads-in one bitstream.

cs.AR↗

arXiv2026

MERIT: Multi-domain Efficient RAW Image Translation

RAW images captured by different camera sensors exhibit substantial domain shifts due to varying spectral responses, noise characteristics, and tone behaviors, complicating their direct use in downstream computer vision tasks. Prior methods address this problem by training domain-specific RAW-to-RAW translators for each source-target pair, but such approaches do not scale to real-world scenarios involving multiple types of commercial cameras. In this work, we introduce MERIT, the first unified framework for multi-domain RAW image translation, which leverages a single model to perform translations across arbitrary camera domains. To address domain-specific noise discrepancies, we propose a sensor-aware noise modeling loss that explicitly aligns the signal-dependent noise statistics of the generated images with those of the target domain. We further enhance the generator with a conditional multi-scale large kernel attention module for improved context and sensor-aware feature modeling. To facilitate standardized evaluation, we introduce MDRAW, the first dataset tailored for multi-domain RAW image translation, comprising both paired and unpaired RAW captures from five diverse camera sensors across a wide range of scenes. Extensive experiments demonstrate that MERIT outperforms prior models in both quality (5.56 dB improvement) and scalability (80% reduction in training iterations).

cs.CV↗

arXiv2026

Bivariate partial mapping for detecting causality in complex non-autonomous system

Identifying causality is fundamental for human understanding of the world, where complex non-autonomous systems such as species population changes, brain activities, etc. are extensively existed. Since the phase spaces of such systems are not manifolds, the existing method based on convergent cross mapping is not applicable. This paper proposes a novel bivariate partial mapping method for detecting causality in complex non-autonomous systems. It transforms a non-autonomous system to an autonomous skew product system, and then, by considering the causality changes due to the transformation, detects causality of the original non-autonomous system from the transformed skew product system. The effectiveness of the proposed method is verified by mathematical cases and a real brain activity case, showing that the proposed method successfully detects the causality in complex non-autonomous systems.

math.DS↗

arXiv2026

A Scoping Review of AI-Driven Digital Interventions in Mental Health Care: Mapping Applications Across Screening, Support, Monitoring, Prevention, and Clinical Education

Artificial intelligence (AI)-enabled digital interventions, including Generative AI (GenAI) and Human-Centered AI (HCAI), are increasingly used to expand access to digital psychiatry and mental health care. This PRISMA-ScR scoping review maps the landscape of AI-driven mental health (mHealth) technologies across five critical phases: pre-treatment (screening/triage), treatment (therapeutic support), post-treatment (remote patient monitoring), clinical education, and population-level prevention. We synthesized 36 empirical studies implemented through early 2024, focusing on Large Language Models (LLMs), machine learning (ML) models, and autonomous conversational agents. Key use cases involve referral triage, empathic communication enhancement, and AI-assisted psychotherapy delivered via chatbots and voice agents. While benefits include reduced wait times and increased patient engagement, we address recurring challenges like algorithmic bias, data privacy, and human-AI collaboration barriers. By introducing a novel four-pillar framework, this review provides a comprehensive roadmap for AI-augmented mental health care, offering actionable insights for researchers, clinicians, and policymakers to develop safe, effective, and equitable digital health interventions.

cs.CY↗

arXiv2026

cyclinbayes: Bayesian Causal Discovery with Linear Non-Gaussian Directed Acyclic and Cyclic Graphical Models

We introduce cyclinbayes, an open-source R package for discovering linear causal relationships with both acyclic and cyclic structures. The package employs scalable Bayesian approaches with spike-and-slab priors to learn directed acyclic graphs (DAGs) and directed cyclic graphs (DCGs) under non-Gaussian noise. A central feature of cyclinbayes is comprehensive uncertainty quantification, including posterior edge inclusion probabilities, posterior probabilities of network motifs, and posterior probabilities over entire graph structures. Our implementation addresses two limitations in existing software: (1) while methods for linear non-Gaussian DAG learning are available in R and Python, they generally lack proper uncertainty quantification, and (2) reliable implementations for linear non-Gaussian DCG remain scarce. The package implements computationally efficient hybrid MCMC algorithms that scale to large datasets. Beyond uncertainty quantification, we propose a new decision-theoretic approach to summarize posterior samples of graphs, yielding principled point estimates based on posterior expected loss such as posterior expected structural Hamming distance and structural intervention distance. The package, a supplementary material, and a tutorial are available on GitHub at https://github.com/roblee01/cyclinbayes.

stat.CO↗

arXiv2026

Bayesian Multiple Multivariate Density-Density Regression

We propose the first approach for multiple multivariate density-density regression (MDDR), making it possible to consider the regression of a multivariate density-valued response on multiple multivariate density-valued predictors. The core idea is to define a fitted distribution using a sliced Wasserstein barycenter (SWB) of push-forwards of the predictors and to quantify deviations from the observed response using the sliced Wasserstein (SW) distance. Regression functions, which map predictors' supports to the response support, and barycenter weights are inferred within a generalized Bayes framework, enabling principled uncertainty quantification without requiring a fully specified likelihood. The inference process can be seen as an instance of an inverse SWB problem. We establish theoretical guarantees, including the stability of the SWB under perturbations of marginals and barycenter weights, sample complexity of the generalized likelihood, and posterior consistency. For practical inference, we introduce a differentiable approximation of the SWB and a smooth reparameterization to handle the simplex constraint on barycenter weights, allowing efficient gradient-based MCMC sampling. We demonstrate MDDR in an application to inference for population-scale single-cell data. Posterior analysis under the MDDR model in this example includes inference on communication between multiple source/sender cell types and a target/receiver cell type. The proposed approach provides accurate fits, reliable predictions, and interpretable posterior estimates of barycenter weights, which can be used to construct sparse cell-cell communication networks.

stat.ME↗

arXiv2025

"Even GPT Can Reject Me": Conceptualizing Abrupt Refusal Secondary Harm (ARSH) and Reimagining Psychological AI Safety with Compassionate Completion Standard (CCS)

Large Language Models (LLMs) and AI chatbots are increasingly used for emotional and mental health support due to their low cost, immediacy, and accessibility. However, when safety guardrails are triggered, conversations may be abruptly terminated, introducing a distinct form of emotional disruption that can exacerbate distress and elevate risk among already vulnerable users. As this phenomenon gains attention, this viewpoint introduces Abrupt Refusal Secondary Harm (ARSH) as a conceptual framework to describe the psychological impacts of sudden conversational discontinuation caused by AI safety protocols. Drawing on counseling psychology and communication science as conceptual heuristics, we argue that abrupt refusals can rupture perceived relational continuity, evoke feelings of rejection or shame, and discourage future help seeking. To mitigate these risks, we propose a design hypothesis, the Compassionate Completion Standard (CCS), a refusal protocol grounded in Human Centered Design (HCD) that maintains safety constraints while preserving relational coherence. CCS emphasizes empathetic acknowledgment, transparent boundary articulation, graded conversational transition, and guided redirection, replacing abrupt disengagement with psychologically attuned closure. By integrating awareness of ARSH into AI safety design, developers and policymakers can reduce preventable iatrogenic harm and advance a more psychologically informed approach to AI governance. Rather than presenting incremental empirical findings, this viewpoint contributes a timely conceptual framework, articulates a testable design hypothesis, and outlines a coordinated research agenda for improving psychological safety in human AI interaction.

cs.CY↗

arXiv2025

A Dependent Feature Allocation Model Based on Random Fields

We introduce a flexible framework for modeling dependent feature allocations. Our approach addresses limitations in traditional nonparametric methods by directly modeling the logit-probability surface of the feature paintbox, enabling the explicit incorporation of covariates and complex but tractable dependence structures. The core of our model is a Gaussian Markov Random Field (GMRF), which we use to robustly decompose the latent field, separating a structural component based on the baseline covariates from intrinsic, unstructured heterogeneity. This structure is not a rigid grid but a sparse k-nearest neighbors graph derived from the latent geometry in the data, ensuring high-dimensional tractability. We extend this framework to a dynamic spatio-temporal process, allowing item effects to evolve via an Ornstein-Uhlenbeck process. Feature correlations are captured using a low-rank factorization of their joint prior. We demonstrate our model's utility by applying it to a polypharmacy dataset, successfully inferring latent health conditions from patient drug profiles.

stat.ME↗

arXiv2025

Spatially Varying Gene Regulatory Networks via Bayesian Nonparametric Covariate-Dependent Directed Cyclic Graphical Models

Spatial transcriptomics technologies enable the measurement of gene expression with spatial context, providing opportunities to understand how gene regulatory networks vary across tissue regions. However, existing graphical models focus primarily on undirected graphs or directed acyclic graphs, limiting their ability to capture feedback loops that are prevalent in gene regulation. Moreover, ensuring the so-called stability condition of cyclic graphs, while allowing graph structures to vary continuously with spatial covariates, presents significant statistical and computational challenges. We propose BNP-DCGx, a Bayesian nonparametric approach for learning spatially varying gene regulatory networks via covariate-dependent directed cyclic graphical models. Our method introduces a covariate-dependent random partition as an intermediary layer in a hierarchical model, which discretizes the covariate space into clusters with cluster-specific stable directed cyclic graphs. Through partition averaging, we obtain smoothly varying graph structures over space while maintaining theoretical guarantees of stability. We develop an efficient parallel tempered Markov chain Monte Carlo algorithm for posterior inference and demonstrate through simulations that our method accurately recovers both piecewise constant and continuously varying graph structures. Application to spatial transcriptomics data from human dorsolateral prefrontal cortex reveals spatially varying regulatory networks with feedback loops, identifies potential cell subtypes within established cell types based on distinct regulatory mechanisms, and provides new insights into spatial organization of gene regulation in brain tissue.

stat.ME↗

arXiv2025

Cauchy-Schwarz Fairness Regularizer

Group fairness in machine learning is often enforced by adding a regularizer that reduces the dependence between model predictions and sensitive attributes. However, existing regularizers are built on heterogeneous distance measures and design choices, which makes their behavior hard to reason about and their performance inconsistent across tasks. This raises a basic question: what properties make a good fairness regularizer? We address this question by first organizing existing in-process methods into three families: (i) matching prediction statistics across sensitive groups, (ii) aligning latent representations, and (iii) directly minimizing dependence between predictions and sensitive attributes. Through this lens, we identify desirable properties of the underlying distance measure, including tight generalization bounds, robustness to scale differences, and the ability to handle arbitrary prediction distributions. Motivated by these properties, we propose a Cauchy-Schwarz (CS) fairness regularizer that penalizes the empirical CS divergence between prediction distributions conditioned on sensitive groups. Under a Gaussian comparison, we show that CS divergence yields a tighter bound than Kullback-Leibler divergence, Maximum Mean Discrepancy, and the mean disparity used in Demographic Parity, and we discuss how these advantages translate to a distribution-free, kernel-based estimator that naturally extends to multiple sensitive attributes. Extensive experiments on four tabular benchmarks and one image dataset demonstrate that the proposed CS regularizer consistently improves Demographic Parity and Equal Opportunity metrics while maintaining competitive accuracy, and achieves a more stable utility-fairness trade-off across hyperparameter settings compared to prior regularizers.

cs.LG↗