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Yang Su

Publications and source records attributed to Yang Su.

At least 127 records · Page 7Linked to original sources
arXiv2022

A Quantitative Analysis of Dynamic Mechanisms Regulating HIV Latency and Activation

Objective: The reservoir of human immunodeficiency virus (HIV) latently infected cells is the major obstacle for eradication of acquired immunodeficiency syndrome (AIDS). Due to the noisy environment and multiple influencing factors in the organism, current dynamical models cannot reach a common understanding of the molecular mechanism of HIV latency. In this work, through a new dynamical structure decomposition, the deterministic part of the equation can be separated from the stochastic noise. Thus, the fixed-point analysis of ordinary differential equation is enough to obtain the different steady states of the system. Methods: We established a dynamical model of HIV transcription process by using continuous stochastic differential equations, which simplifies the dimensions of equations needed to describe the system and increases the explorable space of the model. Different states between latency and activation of virus and their relations can be intuitively represented by potential functions and probability distribution functions. Results: Based on our model, the influence of different dynamical parameters on stability is quantitatively analyzed, the parameter ranges of the system in bistable and monostable states are obtained respectively. The theoretical basis of this work is verified by comparing the effects of different factors on dynamic bifurcation with the results of biological experiments. Conclusion: This paper goes beyond previous discrete stochastic methods, and can quantitatively analyze the dynamic mechanism of HIV transcriptional regulation through ordinary differential equations, which is beneficial to the promotion to deal with the high-dimensional situation, and further study the occurrence and development of AIDS in vivo, so as to guide the design of experiments and search for clinical treatment.

physics.bio-ph↗
arXiv2022

Dependence of Molecular Cloud Samples on Angular Resolution, Sensitivity, and Algorithms

In this work, we investigate the observational and algorithmic effects on molecular cloud samples identified from position-position-velocity (PPV) space. By smoothing and cutting off the high quality data of the Milky Way Imaging Scroll Painting (MWISP) survey, we extract various molecular cloud samples from those altered data with the DBSCAN (density-based spatial clustering of applications with noise) algorithm. Those molecular cloud samples are subsequently used to gauge the significance of sensitivity, angular/velocity resolution, and DBSCAN parameters. Two additional surveys, the FCRAO Outer Galaxy Survey (OGS) and the CfA-Chile 1.2 m complete CO (CfA-Chile) survey, are used to verify the MWISP results. We found that molecular cloud catalogs are not unique and the boundary and therefore the number shows strong variation with angular resolution and sensitivity. At low angular resolution (large beam sizes), molecular clouds merge together in PPV space, while low sensitivity (high cutoffs) misses small faint molecular clouds and takes bright parts of large molecular clouds as single ones. At high angular resolution and sensitivity, giant molecular clouds (GMCs) are resolved into individual clouds, and their diffuse components are also revealed. Consequently, GMCs are more appropriately interpreted as clusters or aggregates of molecular clouds, i.e., GMCs represent molecular cloud samples themselves.

astro-ph.GA↗
arXiv2022

CO Emission Delineating the Interface between the Milky Way Nuclear Wind Cavity and the Gaseous Disk

Based on the MWISP survey, we study high-z CO emission toward the tangent points, in which the distances of the molecular clouds (MCs) are well determined. In the region of l=12-26 deg and |b|<5.1 deg, a total of 321 MCs with |z|> 110 pc are identified, of which nearly 30 extreme high-z MCs (EHMCs at |z|> 260 pc) are concentrated in a narrow region of R_GC=2.6-3.1 kpc. The EHMC concentrations, together with other high-z MCs at R_GC=2.3-2.6 kpc, constitute molecular crater-wall structures surrounding the edges of the HI voids that are physically associated with the Fermi bubbles. Intriguingly, some large high-z MCs, which lie in the crater walls above and below the Galactic plane, show cometary structures with the head toward the plane, favouring the scenario that the entrained molecular gas moves with the multi-phase flows from the plane to the high-z regions. We suggest that the Milky Way nuclear wind has a significant impact on the Galactic gaseous disk. The powerful nuclear wind at ~3-6 Myr ago is likely responsible for the observational features, (1) the enhanced CO gas lying in the edges of the HI voids, (2) the deficiency of atomic and molecular gas within R_GC<3 kpc, (3) the possible connection between the EHMC concentrations and the 3-kpc arm, and (4) the elongated high-z MCs with the tail pointing away from the Galactic plane.

astro-ph.GA↗
arXiv2022

Wisecr: Secure Simultaneous Code Disseminationto Many Batteryless Computational RFID Devices

Emerging ultra-low-power tiny scale computing devices in Cyber-Physical Systems %and Internet of Things (IoT) run on harvested energy, are intermittently powered, have limited computational capability, and perform sensing and actuation functions under the control of a dedicated firmware operating without the supervisory control of an operating system. Wirelessly updating or patching the firmware of such devices is inevitable. We consider the challenging problem of simultaneous and secure firmware updates or patching for a typical class of such devices -- Computational Radio Frequency Identification (CRFID) devices. We propose Wisecr, the first secure and simultaneous wireless code dissemination mechanism to multiple devices that prevent malicious code injection attacks and intellectual property (IP) theft, whilst enabling remote attestation of code installation. Importantly, Wisecr is engineered to comply with existing ISO compliant communication protocol standards employed by CRFID devices and systems. We comprehensively evaluate Wisecr's overhead, demonstrate its implementation over standards-compliant protocols, analyze its security and implement an end-to-end realization with popular CRFID devices -- the open-source code is released on GitHub.

cs.CR↗
arXiv2022

Leaving Your Things Unattended is No Joke! Memory Bus Snooping and Open Debug Interface Exploits

Internet of Things devices are widely adopted by the general population. People today are more connected than ever before. The widespread use and low-cost driven construction of these devices in a competitive marketplace render Internet-connected devices an easier and attractive target for malicious actors. This paper demonstrates non-invasive physical attacks against IoT devices in two case studies in a tutorial style format. The study focuses on demonstrating the: i)exploitation of debug interfaces, often left open after manufacture; and ii)the exploitation of exposed memory buses. We illustrate a person could commit such attacks with entry-level knowledge, inexpensive equipment, and limited time (in 8 to 25 minutes).

cs.CR↗
arXiv2022

X-ray fine structure of a limb solar flare revealed by Insight-HXMT, RHESSI and Fermi

We conduct a detailed analysis of an M1.3 limb flare occurring on 2017 July 3, which have the X-ray observations recorded by multiple hard X-ray telescopes, including Hard X-ray Modulation Telescope (Insight-HXMT), Ramaty High Energy Solar Spectroscopic Imager (RHESSI), and The Fermi Gamma-ray Space Telescope (FERMI). Joint analysis has also used the EUV imaging data from the Atmospheric Imaging Assembly (AIA) aboard the Solar Dynamic Observatory. The hard X-ray spectral and imaging evolution suggest a lower corona source, and the non-thermal broken power law distribution has a rather low break energy $\sim$ 15 keV. The EUV imaging shows a rather stable plasma configuration before the hard X-ray peak phase, and accompanied by a filament eruption during the hard X-ray flare peak phase. Hard X-ray image reconstruction from RHESSI data only shows one foot point source. We also determined the DEM for the peak phase by SDO/AIA data. The integrated EM beyond 10 MK at foot point onset after the peak phase, while the $>$ 10 MK source around reconnection site began to fade. The evolution of EM and hard X-ray source supports lower corona plasma heating after non-thermal energy dissipation. The combination of hard X-ray spectra and images during the limb flare provides the understanding on the interchange of non-thermal and thermal energies, and relation between lower corona heating and the upper corona instability.

astro-ph.HE↗
arXiv2022

On the various notions of Poincaré duality pair

We establish a number of foundational results on Poincaré spaces which result in several applications. One application settles an old conjecture of C.T.C. Wall in the affirmative. Another result shows that for any natural number n, there exists a finite CW pair $(X,Y)$ satisfying relative Poincaré duality in dimension n with the property that $Y$ fails to satisfy Poincaré duality. We also prove a relative version of a result of Gottlieb about Poincaré duality and fibrations.

math.AT↗
arXiv2021

Fermi-LAT detection of extended gamma-ray emission in the vicinity of SNR G045.7$-$00.4: evidence for escaping cosmic rays interacting with the surrounding molecular clouds

We present the analysis of Fermi Large Area Telecope (LAT) data of the gamma-ray emission in the vicinity of a radio supernova remnant (SNR), G045.7$-$00.4. To study the origin of the gamma-ray emission, we also make use of the CO survey data of Milky Way Imaging Scroll Painting to study the massive molecular gas complex that surrounds the SNR. The whole size of the GeV emission is significantly larger than that of the radio morphology. Above 3 GeV, the GeV emission is resolved into two sources: one is spatially consistent with the position of the SNR with a size comparable to that of the radio emission, and the other is located outside of the western boundary of the SNR and spatially coincident with the densest region of the surrounding molecular cloud. We suggest that the GeV emission of the western source may arise from cosmic rays (CRs) which have escaped the SNR and illuminated the surrounding molecular cloud. We find that the gamma-ray spectra of the western source can be consistently explained by this scenario with a total energy of $\sim 10^{50}{\rm erg}$ in escaping CRs assuming the escape is isotropic.

astro-ph.HE↗
arXiv2021

Spectral evolution of an eruptive polar crown prominence with IRIS observations

Prominence eruption is closely related to coronal mass ejections and is an important topic in solar physics. Spectroscopic observation is an effective way to explore the plasma properties, but the spectral observations of eruptive prominences are rare. In this paper we will introduce an eruptive polar crown prominence with spectral observations from the Interface Region Imaging Spectrograph (IRIS), and try to explain some phenomena that are rarely reported in previous works. The eruptive prominence experiences a slow-rise and fast-rise phase, while the line-of-sight motions of the prominence plasma could be divided into three periods: two hours before the fast-rise phase, opposite Doppler shifts are found at the two sides of the prominence axis;then, red shifts dominate the prominence gradually; in the fast-rise phase, the prominence gets to be blue-shifted. During the second period, a faint component appears in Mg II k window with a narrow line width and a large red shift. A faint region is also found in AIA 304-angstrom images along the prominence spine, and the faint region gets darker during the expansion of the spine. We propose that the opposite Doppler shifts in the first period are a feature of the polar crown prominence that we studied. The red shifts in the second period are possibly due to mass drainage during the elevation of the prominence spine, which could accelerate the eruption in return. The blue shifts in the third period are due to that the prominence erupts toward the observer. We suggest that the faint component appears due to the decreasing of the plasma density, and the latter results from the expansion of the prominence spine.

astro-ph.SR↗
arXiv2021

Feedback from $γ$~Cassiopeiae: Large Expanding Cavity, Accelerating Cometary Globules, and Peculiar X-ray Emission

We present wide-field multi-wavelength observations of $γ$ Cassiopeiae (or $γ$~Cas for short) in order to study its feedback toward the interstellar environment. A large expanding cavity is discovered toward $γ$~Cas in the neutral hydrogen (HI) images at a systemic velocity of about -10 km/s. The measured dimension of the cavity is roughly 2.0 deg $\times$ 1.4 deg (or 6.0 pc $\times$ 4.2 pc at a distance of 168 pc), while the expansion velocity is about 5.0$\pm$0.5 km/s. The CO observations reveal systematic velocity gradients in IC63 (about 20 km/s/pc) and IC59 (about 30 km/s/pc), two cometary globules illuminated by $γ$~Cas, proving fast acceleration of the globules under stellar radiation pressure. The gas kinematics indicate that the cavity is opened by strong stellar wind, which has high potential to lead to the peculiar X-ray emission observed in $γ$~Cas. Our result favors a recent new scenario that emphasizes the roles of stellar wind and binarity in the X-ray emission of the $γ$~Cas stars.

astro-ph.SR↗
arXiv2021

High-Resolution Observations of Prominence Plume Formation with the New Vacuum Solar Telescope

Prominence plumes are evacuated upflows that emerge from bubbles below prominences, whose formation mechanism is still unclear. Here we present a detailed study of plumes in a quiescent prominence using the high-resolution H-alpha filtergrams at the line center as well as line wing at +/-0.4 angstrom from the New Vacuum Solar Telescope. Enhancements of brightening, blue shifts, and turbulence at the fronts of plumes are found during their formation. Some large plumes split at their heads and finger-shaped structures are formed between them. Blue-shifted flows along the bubble-prominence interface are found before and during the plume formation. Our observations are consistent with the hypothesis that prominence plumes are related to coupled Kelvin-Helmholtz and Rayleigh-Taylor (KH/RT) instabilities. Plume splittings and fingers are evidence of RT instability, and the flows may increase the growth rate of KH/RT instabilities. However, the significant turbulence at plume fronts may suggest that the RT instability is triggered by the plumes penetrating into the prominence. In this scenario, extra mechanisms are necessary to drive the plumes.

astro-ph.SR↗
arXiv2021

A Morphological Classification of 18190 Molecular Clouds Identified in $^{12}$CO Data from the MWISP Survey

We attempt to visually classify the morphologies of 18190 molecular clouds, which are identified in the $^{12}$CO(1-0) spectral line data over $\sim$ 450 deg$^{2}$ of the second Galactic quadrant from the Milky Way Imaging Scroll Painting project (MWISP). Using the velocity-integrated intensity maps of the $^{12}$CO(1-0) emission, molecular clouds are first divided into unresolved and resolved ones. The resolved clouds are further classified as non-filaments or filaments. Among the 18190 molecular clouds, $\sim$ 25 $\%$ are unresolved, $\sim$ 64$\%$ are non-filaments, and $\sim$ 11$\%$ are filaments. In the terms of the integrated flux of $^{12}$CO(1-0) spectra of the whole 18190 molecular clouds, $\sim$ 90$\%$ are from filaments, $\sim$ 9$\%$ are from non-filaments, and the rest $\sim$ 1$\%$ are from unresolved sources. Although non-filaments are dominant in the number of the discrete molecular clouds, filaments are the main contributor of $^{12}$CO emission flux. We also present the number distributions of physical parameters of the molecular clouds in our catalog, including their angular sizes, velocity spans, peak intensities of $^{12}$CO(1-0) emission, and $^{12}$CO(1-0) total fluxes. We find that there is a systematic difference between the angular sizes of the non-filaments and filaments, with the filaments tending to have larger angular scales. The H$_{2}$ column densities of them are not significantly different. We also discuss the observational effects, such as those induced by the finite spatial resolution, beam dilution and line-of-sight projection, on the morphological classification of molecular clouds in our sample.

astro-ph.GA↗
arXiv2021

A wide-field CO survey towards the California Molecular Filament

We present the survey of $^{12}$CO/$^{13}$CO/C$^{18}$O (J=1-0) toward the California Molecular Cloud (CMC) within the region of 161.75$^{\circ} \leqslant l \leqslant$ 167.75$^{\circ}$,-9.5$^{\circ} \leqslant b \leqslant $-7.5$^{\circ}$, using the Purple Mountain Observatory (PMO) 13.7 m millimeter telescope. Adopting a distance of 470 pc, the mass of the observed molecular cloud estimated from $^{12}$CO, $^{13}$CO, and C$^{18}$O is about 2.59$\times$10$^{4}$ M$_\odot$, 0.85$\times$10$^{4}$ M$_\odot$, and 0.09$\times$10$^{4}$ M$_\odot$, respectively. A large-scale continuous filament extending about 72 pc is revealed from the $^{13}$CO images. A systematic velocity gradient perpendicular to the major axis appears and is measured to be $\sim$ 0.82 km s$^{-1}$ pc$^{-1}$. The kinematics along the filament shows an oscillation pattern with a fragmentation wavelength of $\sim$ 2.3 pc and velocity amplitude of $\sim$ 0.92 km s$^{-1}$, which may be related with core-forming flows. Furthermore, assuming an inclination angle to the plane of the sky of 45$^{\circ}$, the estimated average accretion rate is $\sim$ 101 M$_\odot$ Myr$^{-1}$ for the cluster LkH$α$ 101 and $\sim$ 21 M$_\odot$ Myr$^{-1}$ for the other regions. In the C$^{18}$O observations, the large-scale filament could be resolved into multiple substructures and their dynamics are consistent with the scenario of filament formation from converging flows. Approximately 225 C$^{18}$O cores are extracted, of which 181 are starless cores. Roughly 37$\%$ (67/181) of the starless cores have $α_{\text{vir}}$ less than 1. Twenty outflow candidates are identified along the filament. Our results indicate active early-phase star formation along the large-scale filament in the CMC region.

astro-ph.GA↗
arXiv2021

Improved Measurements of Molecular Cloud Distances Based on Global Search

The principle of the background-eliminated extinction-parallax (BEEP) method is examining the extinction difference between on- and off-cloud regions to reveal the extinction jump caused by molecular clouds, thereby revealing the distance in complex dust environments. The BEEP method requires high-quality images of molecular clouds and high-precision stellar parallaxes and extinction data, which can be provided by the Milky Way Imaging Scroll Painting (MWISP) CO survey and the Gaia DR2 catalog, as well as supplementary AV extinction data. In this work, the BEEP method is further improved (BEEP-II) to measure molecular cloud distances in a global search manner. Applying the BEEP-II method to three regions mapped by the MWISP CO survey, we collectively measured 238 distances for 234 molecular clouds. Compared with previous BEEP results, the BEEP-II method measures distances efficiently, particularly for those molecular clouds with large angular size or in complicated environments, making it suitable for distance measurements of molecular clouds in large samples.

astro-ph.GA↗
arXiv2021

Examinations of CO completeness based on three independent CO surveys

We report the global properties recovered by an ongoing CO survey of the Milky Way Imaging Scroll Painting (MWISP) toward the Galactic outskirts. %To better understand the observational biases, Our results are also compared to those extracted by a uniform decomposition method from the CfA 1.2 m CO survey and the FCRAO 14 m outer Galaxy survey (OGS). We find that more extended and unseen structures are present in the MWISP data. The total flux across the disk recovered by the MWISP survey is 1.6 times larger than those recovered by the CfA and OGS surveys in the case of the same resolution. The discrepancies are scaling with distance. For example, in the outermost OSC arm, the flux ratios for MWISP-to-CfA and MWISP-to-OGS increase up to 43.8 and 7.4, respectively. Nonetheless, the census of molecular gas in our Galaxy is still far from complete by the MWISP, with flux completeness of $<$58%. The total mass ratios of the tabulated molecular clouds between different surveys are similar to the CO flux ratio. The application of these ratios to the total H$_{\rm 2}$ mass of our Galaxy yields a correction factor of at least 1.4, meaning that the H$_{\rm 2}$ mass of our Galaxy should be at least 40% more massive than previously determined. Including the completeness correction, an even more significant fraction of the matter should be contributed by baryonic matter. The mass spectrum in the outer Galactic plane is better described by a non-truncating power-law with $γ$=$-$1.83$\pm$0.05, and an upper mass of $M_0$=(1.3$\pm$0.5)$\times$10$^{\rm 6}$ $M_\odot$.

astro-ph.GA↗
arXiv2021

Investigating the nature of MGRO J1908+06 with multiwavelength observations

The unidentified TeV source MGRO J1908+06, with emission extending from hundreds of GeV to beyond 100TeV, is one of the most intriguing sources in the Galactic plane. MGRO J1908+06 spatially associates with an IceCube hotspot of neutrino emission. Although the hotspot is not significant yet, this suggests a possible hadronic origin of the observed gamma-ray radiation. Here we describe a multiwavelength analysis on MGRO J1908+06 to determine its nature. We identify, for the first time, an extended GeV source as the counterpart of MGRO J1908+06, discovering possibly associated molecular clouds (MCs). The GeV spectrum shows two well-differentiated components: a soft spectral component below $\sim10$ GeV, and a hard one ($Γ\sim1.6$) above these energies. The lower-energy part is likely associated with the dense MCs surrounding the supernova remnant SNR G40.5$-$0.5, whereas the higher-energy component, which connects smoothly with the spectrum observed in TeV range, resembles the inverse Compton emission observed in relic pulsar wind nebulae. This simple scenario seems to describe the data satisfactorily, but raises questions about the interpretation of the emission at hundreds of TeV. In this scenario, no detectable neutrino flux would be expected.

astro-ph.HE↗
arXiv2021

Molecular gas distribution perpendicular to the Galactic plane

We use the ~370 square degrees data from the MWISP CO survey to study the vertical distribution of the molecular clouds (MCs) toward the tangent points in the region of l=[16,52]deg and |b|<5.1deg. The molecular disk consists of two components with the layer thickness (FWHM) of ~85pc and ~280pc, respectively. In the inner Galaxy, the molecular mass in the thin disk is dominant, while the molecular mass traced by the discrete MCs with weak CO emission in the thick disk is probably <10% of the whole molecular disk. For the CO gas in the thick disk, we identified 1055 high-z MCs that are >100pc from the Galactic plane. However, only a few samples (i.e., 32 MCs) are located in the |z|>360pc region. Typically, the discrete MCs of the thick disk population have a median peak temperature of 2.1 K, a median velocity dispersion of 0.8km/s, and a median effective radius of 2.5pc. The median surface density of these MCs is 6.8 Msun/pc^2, indicating very faint CO emission for these high-z MCs. The cloud-cloud velocity dispersion is 4.9+-1.3 km/s and a linear variation with a slope of -0.4 km/s/kpc is obtained in the region of R_GC=2.2-6.4kpc. Assuming that these clouds are supported by their turbulent motions against the gravitational pull of the disk, a model of rho0(R) = 1.28exp(-R/3.2kpc) Msun/pc^3 can be used to describe the distribution of the total mass density in the Galactic midplane.

astro-ph.GA↗