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Yiwei Gao

Publications and source records attributed to Yiwei Gao.

5 recordsLinked to original sources

Deterministic Algorithm for Non-monotone Submodular Maximization under Matroid and Knapsack Constraints

Submodular maximization constitutes a prominent research topic in combinatorial optimization and theoretical computer science, with extensive applications across diverse domains. While substantial advancements have been achieved in approximation algorithms for submodular maximization, the majority of algorithms yielding high approximation guarantees are randomized. In this work, we investigate deterministic approximation algorithms for maximizing non-monotone submodular functions subject to matroid and knapsack constraints. For the two distinct constraint settings, we propose novel deterministic algorithms grounded in an extended multilinear extension framework. Under matroid constraints, our algorithm achieves an approximation ratio of $(0.385 - \epsilon)$, whereas for knapsack constraints, the proposed algorithm attains an approximation ratio of $(0.367 -\epsilon)$. Both algorithms run in $\mathrm{poly}(n)$ query complexity, where $n$ is the size of the ground set, and improve upon the state-of-the-art deterministic approximation ratios of $(0.367 - \epsilon)$ for matroid constraints and $0.25$ for knapsack constraints.

cs.DS

High-yield atmospheric water capture via bioinspired material segregation

Atmospheric water harvesting is urgently needed given increasing global water scarcity. Current sorbent-based devices that cycle between water capture and release have low harvesting rates. We envision a radically different multi-material architecture with segregated and simultaneous capture and release. This way, proven fast-release mechanisms that approach theoretical limits can be incorporated; however, no capture mechanism exists to supply liquid adequately for release. Inspired by tree frogs and airplants, our capture approach transports water through a hydrogel membrane ``skin'' into a liquid desiccant. We report an extraordinarily high capture rate of 5.50 $\text{kg}\,\text{m}^{-2}\,\text{d}^{-1}$ at a low humidity of 35%, limited by the convection of air to the device. At higher humidities, we demonstrate up to 16.9 $\text{kg}\,\text{m}^{-2}\,\text{d}^{-1}$, exceeding theoretical limits for release. Simulated performance of a hypothetical one-square-meter device shows that water could be supplied to two to three people in dry environments. This work is a significant step toward providing new resources to water-scarce regions.

physics.flu-dyn

Kainate receptor modulation by NETO2

Glutamate-gated kainate receptors (KARs) are ubiquitous in the central nervous system of vertebrates, mediate synaptic transmission on post-synapse, and modulate transmitter release on pre-synapse. In the brain, the trafficking, gating kinetics, and pharmacology of KARs are tightly regulated by Neuropilin and tolloid-like proteins (Netos). Here we report cryo-EM structures of homo-tetrameric GluK2 in complex with Neto2 at inhibited and desensitized states, illustrating variable stoichiometry of GluK2-Neto2 complexes, with one or two Neto2 subunits associate with the GluK2. We find that Neto2 accesses only two broad faces of KARs, intermolecularly crosslinking the lower-lobe of ATDA/C, upper-lobe of LBDB/D, and lower-lobe of LBDA/C, illustrating how Neto2 regulates receptor-gating kinetics. The transmembrane helix of Neto2 is positioned proximal to the selectivity filter and competes with the amphiphilic H1-helix after M4 for interacting with an ICD formed by the M1-M2 linkers of the receptor, revealing how rectification is regulated by Neto2.

q-bio.BM

Quantifying the trade-off between stiffness and permeability in hydrogels

Hydrogels have a distinct combination of mechanical and water-transport behaviors. As hydrogels stiffen, they become less permeable. Here, we combine semi-dilute polymer theory with the Kozeny-Carman equation to develop a simple scaling law describing the relationship between hydraulic permeability and mechanical stiffness. We find that these properties are dictated by the polymer strand spacing, explained via analogy of a bowl of noodle soup. We find a remarkably close agreement between our scaling law and experimental results across four different polymer families with varied crosslinkings.

cond-mat.soft

Scaling laws to predict humidity-induced swelling and stiffness in hydrogels

From pasta to biological tissues to contact lenses, gel and gel-like materials inherently soften as they swell with water. In dry, low-relative-humidity environments, these materials stiffen as they de-swell with water. Here, we use semi-dilute polymer theory to develop a simple power-law relationship between hydrogel elastic modulus and swelling. From this relationship, we predict hydrogel stiffness or swelling at arbitrary relative humidities. Our close predictions of properties of hydrogels across three different polymer mesh families at varying crosslinking densities and relative humidities demonstrate the validity and generality of our understanding. This predictive capability enables more rapid material discovery and selection for hydrogel applications in varying humidity environments.

cond-mat.soft