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Yizhi Wang

Publications and source records attributed to Yizhi Wang.

At least 37 records · Page 2Linked to original sources

Bridging Efficiency and Transparency: Explainable CoT Compression in Multimodal Large Reasoning Models

Long chains of thought (Long CoTs) are widely employed in multimodal reasoning models to tackle complex tasks by capturing detailed visual information. However, these Long CoTs are often excessively lengthy and contain redundant reasoning steps, which can hinder inference efficiency. Compressing these long CoTs is a natural solution, yet existing approaches face two major challenges: (1) they may compromise the integrity of visual-textual reasoning by removing essential alignment cues, and (2) the compression process lacks explainability, making it difficult to discern which information is critical. To address these problems, we propose XMCC, an eXplainable Multimodal CoT Compressor that formulates compression as a sequential decision-making process optimized via reinforcement learning. XMCC can effectively shorten reasoning trajectories while preserving key reasoning steps and answer correctness, and simultaneously generates natural-language explanations for its compression decisions. Extensive experiments on representative multimodal reasoning benchmarks demonstrate that XMCC not only reduces reasoning length but also provides explainable explanations, validating its effectiveness.

cs.AI↗

Matrix Product State on a Quantum Computer

Solving quantum many-body systems is one of the most significant regimes where quantum computing applies. Currently, as a hardware-friendly computational paradigms, variational algorithms are often used for finding the ground energy of quantum many-body systems. However, running large-scale variational algorithms is challenging, because of the noise as well as the obstacle of barren plateaus. In this work, we propose the quantum version of matrix product state (qMPS), and develop variational quantum algorithms to prepare it in canonical forms, allowing to run the variational MPS method, which is equivalent to the Density Matrix Renormalization Group method, on near term quantum devices. Compared with widely used methods such as variational quantum eigensolver, this method can greatly reduce the number of qubits required, and thus can mitigate the effects of Barren Plateaus while obtain comparable or even better accuracy. Our method holds promise for distributed quantum computing, offering possibilities for fusion of different computing systems.

quant-ph↗

StainNet: Scaling Self-Supervised Foundation Models on Immunohistochemistry and Special Stains for Computational Pathology

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI) image analysis or patch-level feature extractors in whole-slide images (WSIs) based on multiple instance learning (MIL). Existing pathology foundation models (PFMs) are typically pre-trained on Hematoxylin-Eosin (H\&E) stained pathology images. However, images such as immunohistochemistry (IHC) and special stains are also frequently used in clinical practice. PFMs pre-trained mainly on H\&E-stained images may be limited in clinical applications involving these non-H\&E images. To address this issue, we propose StainNet, a collection of self-supervised foundation models specifically trained for IHC and special stains in pathology images based on the vision transformer (ViT) architecture. StainNet contains a ViT-Small and a ViT-Base model, both of which are trained using a self-distillation SSL approach on over 1.4 million patch images extracted from 20,231 publicly available IHC and special staining WSIs in the HISTAI database. To evaluate StainNet models, we conduct experiments on three in-house slide-level IHC classification tasks, three in-house ROI-level special stain and two public ROI-level IHC classification tasks to demonstrate their strong ability. We also perform ablation studies such as few-ratio learning and retrieval evaluations, and compare StainNet models with recent larger PFMs to further highlight their strengths. The StainNet model weights are available at https://github.com/WonderLandxD/StainNet.

cs.CV↗

To What Extent Do Token-Level Representations from Pathology Foundation Models Improve Dense Prediction?

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation), practical deployment still lacks a clear, reproducible understanding of how different PFMs behave across datasets and how adaptation choices affect performance and stability. We present PFM-DenseBench, a large-scale benchmark for dense pathology prediction, evaluating 17 PFMs across 18 public segmentation datasets. Under a unified protocol, we systematically assess PFMs with multiple adaptation and fine-tuning strategies, and derive insightful, practice-oriented findings on when and why different PFMs and tuning choices succeed or fail across heterogeneous datasets. We release containers, configs, and dataset cards to enable reproducible evaluation and informed PFM selection for real-world dense pathology tasks. Project Website: https://m4a1tastegood.github.io/PFM-DenseBench

eess.IV↗

Envision: Embodied Visual Planning via Goal-Imagery Video Diffusion

Embodied visual planning aims to enable manipulation tasks by imagining how a scene evolves toward a desired goal and using the imagined trajectories to guide actions. Video diffusion models, through their image-to-video generation capability, provide a promising foundation for such visual imagination. However, existing approaches are largely forward predictive, generating trajectories conditioned on the initial observation without explicit goal modeling, thus often leading to spatial drift and goal misalignment. To address these challenges, we propose Envision, a diffusion-based framework that performs visual planning for embodied agents. By explicitly constraining the generation with a goal image, our method enforces physical plausibility and goal consistency throughout the generated trajectory. Specifically, Envision operates in two stages. First, a Goal Imagery Model identifies task-relevant regions, performs region-aware cross attention between the scene and the instruction, and synthesizes a coherent goal image that captures the desired outcome. Then, an Env-Goal Video Model, built upon a first-and-last-frame-conditioned video diffusion model (FL2V), interpolates between the initial observation and the goal image, producing smooth and physically plausible video trajectories that connect the start and goal states. Experiments on object manipulation and image editing benchmarks demonstrate that Envision achieves superior goal alignment, spatial consistency, and object preservation compared to baselines. The resulting visual plans can directly support downstream robotic planning and control, providing reliable guidance for embodied agents.

cs.CV↗

VIVA: VLM-Guided Instruction-Based Video Editing with Reward Optimization

Instruction-based video editing aims to modify an input video according to a natural-language instruction while preserving content fidelity and temporal coherence. However, existing diffusion-based approaches are often trained on paired data of simple editing operations, which fundamentally limits their ability to generalize to diverse and complex, real-world instructions. To address this generalization gap, we propose VIVA, a scalable framework for instruction-based video editing that leverages VLM-guided encoding and reward optimization. First, we introduce a VLM-based instructor that encodes the textual instruction, the first frame of the source video, and an optional reference image into visually-grounded instruction representations, providing fine-grained spatial and semantic context for the diffusion transformer backbone. Second, we propose a post-training stage, Edit-GRPO, which adapts Group Relative Policy Optimization to the domain of video editing, directly optimizing the model for instruction-faithful, content-preserving, and aesthetically pleasing edits using relative rewards. Furthermore, we propose a data construction pipeline designed to synthetically generate diverse, high-fidelity paired video-instruction data of basic editing operations. Extensive experiments show that VIVA achieves superior instruction following, generalization, and editing quality over state-of-the-art methods. Website: https://viva-paper.github.io

cs.CV↗

ACT-R: Adaptive Camera Trajectories for Single View 3D Reconstruction

We introduce the simple idea of adaptive view planning to multi-view synthesis, aiming to improve both occlusion revelation and 3D consistency for single-view 3D reconstruction. Instead of producing an unordered set of views independently or simultaneously, we generate a sequence of views, leveraging temporal consistency to enhance 3D coherence. More importantly, our view sequence is not determined by a pre-determined and fixed camera setup. Instead, we compute an adaptive camera trajectory (ACT), forming an orbit, which seeks to maximize the visibility of occluded regions of the 3D object to be reconstructed. Once the best orbit is found, we feed it to a video diffusion model to generate novel views around the orbit, which can then be passed to any multi-view 3D reconstruction model to obtain the final result. Our multi-view synthesis pipeline is quite efficient since it involves no run-time training/optimization, only forward inferences by applying pre-trained models for occlusion analysis and multi-view synthesis. Our method predicts camera trajectories that reveal occlusions effectively and produce consistent novel views, significantly improving 3D reconstruction over SOTA alternatives on the unseen GSO dataset. Project Page: https://mingrui-zhao.github.io/ACT-R/

cs.GR↗

From Generic to Specialized: A Subspecialty Diagnostic System Powered by Self-Supervised Learning for Cervical Histopathology

Cervical cancer remains a major malignancy, necessitating extensive and complex histopathological assessments and comprehensive support tools. Although deep learning shows promise, these models still lack accuracy and generalizability. General foundation models offer a broader reach but remain limited in capturing subspecialty-specific features and task adaptability. We introduce the Cervical Subspecialty Pathology (CerS-Path) diagnostic system, developed through two synergistic pretraining stages: self-supervised learning on approximately 190 million tissue patches from 140,000 slides to build a cervical-specific feature extractor, and multimodal enhancement with 2.5 million image-text pairs, followed by integration with multiple downstream diagnostic functions. Supporting eight diagnostic functions, including rare cancer classification and multimodal Q&A, CerS-Path surpasses prior foundation models in scope and clinical applicability. Comprehensive evaluations demonstrate a significant advance in cervical pathology, with prospective testing on 3,173 cases across five centers maintaining 99.38% screening sensitivity and excellent generalizability, highlighting its potential for subspecialty diagnostic translation and cervical cancer screening.

cs.CV↗

MAGREF: Masked Guidance for Any-Reference Video Generation with Subject Disentanglement

We tackle the task of any-reference video generation, which aims to synthesize videos conditioned on arbitrary types and combinations of reference subjects, together with textual prompts. This task faces persistent challenges, including identity inconsistency, entanglement among multiple reference subjects, and copy-paste artifacts. To address these issues, we introduce MAGREF, a unified and effective framework for any-reference video generation. Our approach incorporates masked guidance and a subject disentanglement mechanism, enabling flexible synthesis conditioned on diverse reference images and textual prompts. Specifically, masked guidance employs a region-aware masking mechanism combined with pixel-wise channel concatenation to preserve appearance features of multiple subjects along the channel dimension. This design preserves identity consistency and maintains the capabilities of the pre-trained backbone, without requiring any architectural changes. To mitigate subject confusion, we introduce a subject disentanglement mechanism which injects the semantic values of each subject derived from the text condition into its corresponding visual region. Additionally, we establish a four-stage data pipeline to construct diverse training pairs, effectively alleviating copy-paste artifacts. Extensive experiments on a comprehensive benchmark demonstrate that MAGREF consistently outperforms existing state-of-the-art approaches, paving the way for scalable, controllable, and high-fidelity any-reference video synthesis. Code and model can be found at: https://github.com/MAGREF-Video/MAGREF

cs.CV↗

YpathRAG:A Retrieval-Augmented Generation Framework and Benchmark for Pathology

Large language models (LLMs) excel on general tasks yet still hallucinate in high-barrier domains such as pathology. Prior work often relies on domain fine-tuning, which neither expands the knowledge boundary nor enforces evidence-grounded constraints. We therefore build a pathology vector database covering 28 subfields and 1.53 million paragraphs, and present YpathRAG, a pathology-oriented RAG framework with dual-channel hybrid retrieval (BGE-M3 dense retrieval coupled with vocabulary-guided sparse retrieval) and an LLM-based supportive-evidence judgment module that closes the retrieval-judgment-generation loop. We also release two evaluation benchmarks, YpathR and YpathQA-M. On YpathR, YpathRAG attains Recall@5 of 98.64%, a gain of 23 percentage points over the baseline; on YpathQA-M, a set of the 300 most challenging questions, it increases the accuracies of both general and medical LLMs by 9.0% on average and up to 15.6%. These results demonstrate improved retrieval quality and factual reliability, providing a scalable construction paradigm and interpretable evaluation for pathology-oriented RAG.

cs.CL↗

Virtual Cells: From Conceptual Frameworks to Biomedical Applications

The challenge of translating vast, multimodal biological data into predictive and mechanistic understanding of cellular function is a central theme in modern biology. Virtual cells, or digital cellular twins, have emerged as a critical paradigm to meet this challenge by creating integrative computational models of cellular processes. This review synthesizes the evolution and current state of the virtual cell, from foundational mechanistic frameworks like the Virtual Cell that employ deterministic and stochastic simulations to the recent transformative impact of artificial intelligence and foundation models. We examine the core technological pillars required to build these models, including the integration of various data types, such as single-cell and spatial omics, the spectrum of modeling approaches, and the bioengineering principles that connect simulation to application. We further discuss key applications, frameworks for model benchmarking and validation, and the significant hurdles that remain, including computational scalability, parameter inference, and ethical considerations, which provides a roadmap for development of predictive virtual cells that promise to revolutionize biomedical research and clinical practice.

q-bio.QM↗

Integrated photonic neuromorphic computing: device, architecture, chip, algorithm

Artificial intelligence (AI) has experienced explosive growth in recent years. The large models have been widely applied in various fields, including natural language processing, image generation, and complex decision-making systems, revolutionizing technological paradigms across multiple industries. Nevertheless, the substantial data processing demands during model training and inference result in the computing power bottleneck. Traditional electronic chips based on the von Neumann architecture struggle to meet the growing demands for computing power and power efficiency amid the continuous development of AI. Photonic neuromorphic computing, an emerging solution in the post-Moore era, exhibits significant development potential. Leveraging the high-speed and large-bandwidth characteristics of photons in signal transmission, as well as the low-power consumption advantages of optical devices, photonic integrated computing chips have the potential to overcome the memory wall and power wall issues of electronic chips. In recent years, remarkable advancements have been made in photonic neuromorphic computing. This article presents a systematic review of the latest research achievements. It focuses on fundamental principles and novel neuromorphic photonic devices, such as photonic neurons and photonic synapses. Additionally, it comprehensively summarizes the network architectures and photonic integrated neuromorphic chips, as well as the optimization algorithms of photonic neural networks. In addition, combining with the current status and challenges of this field, this article conducts an in-depth discussion on the future development trends of photonic neuromorphic computing in the directions of device integration, algorithm collaborative optimization, and application scenario expansion, providing a reference for subsequent research in the field of photonic neuromorphic computing.

physics.optics↗

Hierarchical Decision-Making for Autonomous Navigation: Integrating Deep Reinforcement Learning and Fuzzy Logic in Four-Wheel Independent Steering and Driving Systems

This paper presents a hierarchical decision-making framework for autonomous navigation in four-wheel independent steering and driving (4WISD) systems. The proposed approach integrates deep reinforcement learning (DRL) for high-level navigation with fuzzy logic for low-level control to ensure both task performance and physical feasibility. The DRL agent generates global motion commands, while the fuzzy logic controller enforces kinematic constraints to prevent mechanical strain and wheel slippage. Simulation experiments demonstrate that the proposed framework outperforms traditional navigation methods, offering enhanced training efficiency and stability and mitigating erratic behaviors compared to purely DRL-based solutions. Real-world validations further confirm the framework's ability to navigate safely and effectively in dynamic industrial settings. Overall, this work provides a scalable and reliable solution for deploying 4WISD mobile robots in complex, real-world scenarios.

cs.RO↗

Don't Overthink It: A Survey of Efficient R1-style Large Reasoning Models

Recently, Large Reasoning Models (LRMs) have gradually become a research hotspot due to their outstanding performance in handling complex tasks. Among them, DeepSeek R1 has garnered significant attention for its exceptional performance and open-source nature, driving advancements in the research of R1-style LRMs. Unlike traditional Large Language Models (LLMs), these models enhance logical deduction and decision-making capabilities during reasoning by incorporating mechanisms such as long chain-of-thought and self-reflection through reinforcement learning. However, with the widespread application of these models, the problem of overthinking has gradually emerged. Specifically, when generating answers, these models often construct excessively long reasoning chains with redundant or repetitive steps, which leads to reduced reasoning efficiency and may affect the accuracy of the final answer. To this end, various efficient reasoning methods have been proposed, aiming to reduce the length of reasoning paths without compromising model performance and reasoning capability. By reviewing the current research advancements in the field of efficient reasoning methods systematically, we categorize existing works into two main directions based on the lens of single-model optimization versus model collaboration: (1) Efficient Reasoning with Single Model, which focuses on improving the reasoning efficiency of individual models; and (2) Efficient Reasoning with Model Collaboration, which explores optimizing reasoning paths through collaboration among multiple models. Besides, we maintain a public GitHub repository that tracks the latest progress in efficient reasoning methods.

cs.AI↗

Prune&Comp: Free Lunch for Layer-Pruned LLMs via Iterative Pruning with Magnitude Compensation

Layer pruning has emerged as a promising technique for compressing large language models (LLMs) while achieving acceleration proportional to the pruning ratio. In this work, we identify that removing any layer induces a significant magnitude gap in hidden states, resulting in substantial performance degradation. To address this issue, we propose Prune&Comp, a novel plug-and-play layer pruning scheme that leverages magnitude compensation to mitigate such gaps in a training-free manner. Specifically, we first estimate the magnitude gap caused by layer removal and then eliminate this gap by rescaling the remaining weights offline, with zero runtime overhead incurred. We further demonstrate the advantages of Prune&Comp through an iterative pruning strategy. When integrated with an iterative prune-and-compensate loop, Prune&Comp consistently enhances existing layer pruning metrics. For instance, when 5 layers of LLaMA-3-8B are pruned using the prevalent block influence metric, Prune&Comp nearly halves the perplexity and retains 93.19\% of the original model's question-answering performance, outperforming the baseline by 4.01%.

cs.CL↗

3D surface profiling via photonic integrated geometric sensor

Measurements of microscale surface patterns are essential for process and quality control in industries across semiconductors, micro-machining, and biomedicines. However, the development of miniaturized and intelligent profiling systems remains a longstanding challenge, primarily due to the complexity and bulkiness of existing benchtop systems required to scan large-area samples. A real-time, in-situ, and fast detection alternative is therefore highly desirable for predicting surface topography on the fly. In this paper, we present an ultracompact geometric profiler based on photonic integrated circuits, which directly encodes the optical reflectance of the sample and decodes it with a neural network. This platform is free of complex interferometric configurations and avoids time-consuming nonlinear fitting algorithms. We show that a silicon programmable circuit can generate pseudo-random kernels to project input data into higher dimensions, enabling efficient feature extraction via a lightweight one-dimensional convolutional neural network. Our device is capable of high-fidelity, fast-scanning-rate thickness identification for both smoothly varying samples and intricate 3D printed emblem structures, paving the way for a new class of compact geometric sensors.

physics.optics↗

TriCon-SF: A Triple-Shuffle and Contribution-Aware Serial Federated Learning Framework for Heterogeneous Healthcare Data

Serial pipeline training is an efficient paradigm for handling data heterogeneity in cross-silo federated learning with low communication overhead. However, even without centralized aggregation, direct transfer of models between clients can violate privacy regulations and remain susceptible to gradient leakage and linkage attacks. Additionally, ensuring resilience against semi-honest or malicious clients who may manipulate or misuse received models remains a grand challenge, particularly in privacy-sensitive domains such as healthcare. To address these challenges, we propose TriCon-SF, a novel serial federated learning framework that integrates triple shuffling and contribution awareness. TriCon-SF introduces three levels of randomization by shuffling model layers, data segments, and training sequences to break deterministic learning patterns and disrupt potential attack vectors, thereby enhancing privacy and robustness. In parallel, it leverages Shapley value methods to dynamically evaluate client contributions during training, enabling the detection of dishonest behavior and enhancing system accountability. Extensive experiments on non-IID healthcare datasets demonstrate that TriCon-SF outperforms standard serial and parallel federated learning in both accuracy and communication efficiency. Security analysis further supports its resilience against client-side privacy attacks.

cs.LG↗

Subspecialty-Specific Foundation Model for Intelligent Gastrointestinal Pathology

Gastrointestinal (GI) diseases represent a clinically significant burden, necessitating precise diagnostic approaches to optimize patient outcomes. Conventional histopathological diagnosis suffers from limited reproducibility and diagnostic variability. To overcome these limitations, we develop Digepath, a specialized foundation model for GI pathology. Our framework introduces a dual-phase iterative optimization strategy combining pretraining with fine-screening, specifically designed to address the detection of sparsely distributed lesion areas in whole-slide images. Digepath is pretrained on over 353 million multi-scale images from 210,043 H&E-stained slides of GI diseases. It attains state-of-the-art performance on 33 out of 34 tasks related to GI pathology, including pathological diagnosis, protein expression status prediction, gene mutation prediction, and prognosis evaluation. We further translate the intelligent screening module for early GI cancer and achieve near-perfect 99.70% sensitivity across nine independent medical institutions. This work not only advances AI-driven precision pathology for GI diseases but also bridge critical gaps in histopathological practice.

eess.IV↗