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Yuanyuan Wang

Publications and source records attributed to Yuanyuan Wang.

At least 73 records · Page 4Linked to original sources

Diff-CXR: Report-to-CXR generation through a disease-knowledge enhanced diffusion model

Text-To-Image (TTI) generation is significant for controlled and diverse image generation with broad potential applications. Although current medical TTI methods have made some progress in report-to-Chest-Xray (CXR) generation, their generation performance may be limited due to the intrinsic characteristics of medical data. In this paper, we propose a novel disease-knowledge enhanced Diffusion-based TTI learning framework, named Diff-CXR, for medical report-to-CXR generation. First, to minimize the negative impacts of noisy data on generation, we devise a Latent Noise Filtering Strategy that gradually learns the general patterns of anomalies and removes them in the latent space. Then, an Adaptive Vision-Aware Textual Learning Strategy is designed to learn concise and important report embeddings in a domain-specific Vision-Language Model, providing textual guidance for Chest-Xray generation. Finally, by incorporating the general disease knowledge into the pretrained TTI model via a delicate control adapter, a disease-knowledge enhanced diffusion model is introduced to achieve realistic and precise report-to-CXR generation. Experimentally, our Diff-CXR outperforms previous SOTA medical TTI methods by 33.4\% / 8.0\% and 23.8\% / 56.4\% in the FID and mAUC score on MIMIC-CXR and IU-Xray, with the lowest computational complexity at 29.641 GFLOPs. Downstream experiments on three thorax disease classification benchmarks and one CXR-report generation benchmark demonstrate that Diff-CXR is effective in improving classical CXR analysis methods. Notably, models trained on the combination of 1\% real data and synthetic data can achieve a competitive mAUC score compared to models trained on all data, presenting promising clinical applications.

cs.CV↗

TASL-Net: Tri-Attention Selective Learning Network for Intelligent Diagnosis of Bimodal Ultrasound Video

In the intelligent diagnosis of bimodal (gray-scale and contrast-enhanced) ultrasound videos, medical domain knowledge such as the way sonographers browse videos, the particular areas they emphasize, and the features they pay special attention to, plays a decisive role in facilitating precise diagnosis. Embedding medical knowledge into the deep learning network can not only enhance performance but also boost clinical confidence and reliability of the network. However, it is an intractable challenge to automatically focus on these person- and disease-specific features in videos and to enable networks to encode bimodal information comprehensively and efficiently. This paper proposes a novel Tri-Attention Selective Learning Network (TASL-Net) to tackle this challenge and automatically embed three types of diagnostic attention of sonographers into a mutual transformer framework for intelligent diagnosis of bimodal ultrasound videos. Firstly, a time-intensity-curve-based video selector is designed to mimic the temporal attention of sonographers, thus removing a large amount of redundant information while improving computational efficiency of TASL-Net. Then, to introduce the spatial attention of the sonographers for contrast-enhanced video analysis, we propose the earliest-enhanced position detector based on structural similarity variation, on which the TASL-Net is made to focus on the differences of perfusion variation inside and outside the lesion. Finally, by proposing a mutual encoding strategy that combines convolution and transformer, TASL-Net possesses bimodal attention to structure features on gray-scale videos and to perfusion variations on contrast-enhanced videos. These modules work collaboratively and contribute to superior performance. We conduct a detailed experimental validation of TASL-Net's performance on three datasets, including lung, breast, and liver.

cs.CV↗

SimpleSpeech 2: Towards Simple and Efficient Text-to-Speech with Flow-based Scalar Latent Transformer Diffusion Models

Scaling Text-to-speech (TTS) to large-scale datasets has been demonstrated as an effective method for improving the diversity and naturalness of synthesized speech. At the high level, previous large-scale TTS models can be categorized into either Auto-regressive (AR) based (\textit{e.g.}, VALL-E) or Non-auto-regressive (NAR) based models (\textit{e.g.}, NaturalSpeech 2/3). Although these works demonstrate good performance, they still have potential weaknesses. For instance, AR-based models are plagued by unstable generation quality and slow generation speed; meanwhile, some NAR-based models need phoneme-level duration alignment information, thereby increasing the complexity of data pre-processing, model design, and loss design. In this work, we build upon our previous publication by implementing a simple and efficient non-autoregressive (NAR) TTS framework, termed SimpleSpeech 2. SimpleSpeech 2 effectively combines the strengths of both autoregressive (AR) and non-autoregressive (NAR) methods, offering the following key advantages: (1) simplified data preparation; (2) straightforward model and loss design; and (3) stable, high-quality generation performance with fast inference speed. Compared to our previous publication, we present ({\romannumeral1}) a detailed analysis of the influence of speech tokenizer and noisy label for TTS performance; ({\romannumeral2}) four distinct types of sentence duration predictors; ({\romannumeral3}) a novel flow-based scalar latent transformer diffusion model. With these improvement, we show a significant improvement in generation performance and generation speed compared to our previous work and other state-of-the-art (SOTA) large-scale TTS models. Furthermore, we show that SimpleSpeech 2 can be seamlessly extended to multilingual TTS by training it on multilingual speech datasets. Demos are available on: {https://dongchaoyang.top/SimpleSpeech2\_demo/}.

cs.SD↗

Small exciton effective mass in QL Bi2Se2Te: A material platform towards high-temperature excitonic condensate

Using first-principles simulations combined with many-body calculations, we show that two-dimensional free-standing quintuple-layer Bi2Se2Te is an inversion symmetric monolayer expected to achieve spatially indirect exciton with large exciton radius, small exciton effective mass and long exciton lifetime. Such system is theoretically predicted to be a promising platform for realizing excitonic Bose-Einstein condensation and superfluid due to its high phase transition temperatures of ~257 K and ~64.25 K for the BEC and excitonic superfluid, respectively. The importance of spin-orbit coupling is revealed, and the angular momentum selection rules for photon absorption are discussed. This finding suggests the potential of QL Bi2Se2Te monolayer with exotic bosonic bound states provides as a tantalizing high-temperature platform to probe excitonic physics.

cond-mat.mtrl-sci↗

Chest-Diffusion: A Light-Weight Text-to-Image Model for Report-to-CXR Generation

Text-to-image generation has important implications for generation of diverse and controllable images. Several attempts have been made to adapt Stable Diffusion (SD) to the medical domain. However, the large distribution difference between medical reports and natural texts, as well as high computational complexity in common stable diffusion limit the authenticity and feasibility of the generated medical images. To solve above problems, we propose a novel light-weight transformer-based diffusion model learning framework, Chest-Diffusion, for report-to-CXR generation. Chest-Diffusion employs a domain-specific text encoder to obtain accurate and expressive text features to guide image generation, improving the authenticity of the generated images. Meanwhile, we introduce a light-weight transformer architecture as the denoising model, reducing the computational complexity of the diffusion model. Experiments demonstrate that our Chest-Diffusion achieves the lowest FID score 24.456, under the computation budget of 118.918 GFLOPs, which is nearly one-third of the computational complexity of SD.

cs.CV↗

UniAudio 1.5: Large Language Model-driven Audio Codec is A Few-shot Audio Task Learner

The Large Language models (LLMs) have demonstrated supreme capabilities in text understanding and generation, but cannot be directly applied to cross-modal tasks without fine-tuning. This paper proposes a cross-modal in-context learning approach, empowering the frozen LLMs to achieve multiple audio tasks in a few-shot style without any parameter update. Specifically, we propose a novel and LLMs-driven audio codec model, LLM-Codec, to transfer the audio modality into the textual space, \textit{i.e.} representing audio tokens with words or sub-words in the vocabulary of LLMs, while keeping high audio reconstruction quality. The key idea is to reduce the modality heterogeneity between text and audio by compressing the audio modality into a well-trained LLMs token space. Thus, the audio representation can be viewed as a new \textit{foreign language}, and LLMs can learn the new \textit{foreign language} with several demonstrations. In experiments, we investigate the performance of the proposed approach across multiple audio understanding and generation tasks, \textit{e.g.} speech emotion classification, audio classification, text-to-speech generation, speech enhancement, etc. The experimental results demonstrate that the LLMs equipped with the proposed LLM-Codec, named as UniAudio 1.5, prompted by only a few examples, can achieve the expected functions in simple scenarios. It validates the feasibility and effectiveness of the proposed cross-modal in-context learning approach. To facilitate research on few-shot audio task learning and multi-modal LLMs, we have open-sourced the LLM-Codec model.

cs.SD↗

Nuclear mass table in deformed relativistic Hartree-Bogoliubov theory in continuum, II: Even-$Z$ nuclei

The mass table in the deformed relativistic Hartree-Bogoliubov theory in continuum (DRHBc) with the PC-PK1 density functional has been established for even-$Z$ nuclei with $8\le Z\le120$, extended from the previous work for even-even nuclei [Zhang $\it{et.~al.}$ (DRHBc Mass Table Collaboration), At. Data Nucl. Data Tables 144, 101488 (2022)]. The calculated binding energies, two-nucleon and one-neutron separation energies, root-mean-square (rms) radii of neutron, proton, matter, and charge distributions, quadrupole deformations, and neutron and proton Fermi surfaces are tabulated and compared with available experimental data. A total of 4829 even-$Z$ nuclei are predicted to be bound, with an rms deviation of 1.477 MeV from the 1244 mass data. Good agreement with the available experimental odd-even mass differences, $α$ decay energies, and charge radii is also achieved. The description accuracy for nuclear masses and nucleon separation energies as well as the prediction for drip lines is compared with the results obtained from other relativistic and nonrelativistic density functional. The comparison shows that the DRHBc theory with PC-PK1 provides an excellent microscopic description for the masses of even-$Z$ nuclei. The systematics of the nucleon separation energies, odd-even mass differences, pairing energies, two-nucleon gaps, $α$ decay energies, rms radii, quadrupole deformations, potential energy curves, neutron density distributions, and neutron mean-field potentials are discussed.

nucl-th↗

Identifiability and Asymptotics in Learning Homogeneous Linear ODE Systems from Discrete Observations

Ordinary Differential Equations (ODEs) have recently gained a lot of attention in machine learning. However, the theoretical aspects, e.g., identifiability and asymptotic properties of statistical estimation are still obscure. This paper derives a sufficient condition for the identifiability of homogeneous linear ODE systems from a sequence of equally-spaced error-free observations sampled from a single trajectory. When observations are disturbed by measurement noise, we prove that under mild conditions, the parameter estimator based on the Nonlinear Least Squares (NLS) method is consistent and asymptotic normal with $n^{-1/2}$ convergence rate. Based on the asymptotic normality property, we construct confidence sets for the unknown system parameters and propose a new method to infer the causal structure of the ODE system, i.e., inferring whether there is a causal link between system variables. Furthermore, we extend the results to degraded observations, including aggregated and time-scaled ones. To the best of our knowledge, our work is the first systematic study of the identifiability and asymptotic properties in learning linear ODE systems. We also construct simulations with various system dimensions to illustrate the established theoretical results.

stat.ML↗

Consistency Model is an Effective Posterior Sample Approximation for Diffusion Inverse Solvers

Diffusion Inverse Solvers (DIS) are designed to sample from the conditional distribution $p_θ(X_0|y)$, with a predefined diffusion model $p_θ(X_0)$, an operator $f(\cdot)$, and a measurement $y=f(x'_0)$ derived from an unknown image $x'_0$. Existing DIS estimate the conditional score function by evaluating $f(\cdot)$ with an approximated posterior sample drawn from $p_θ(X_0|X_t)$. However, most prior approximations rely on the posterior means, which may not lie in the support of the image distribution, thereby potentially diverge from the appearance of genuine images. Such out-of-support samples may significantly degrade the performance of the operator $f(\cdot)$, particularly when it is a neural network. In this paper, we introduces a novel approach for posterior approximation that guarantees to generate valid samples within the support of the image distribution, and also enhances the compatibility with neural network-based operators $f(\cdot)$. We first demonstrate that the solution of the Probability Flow Ordinary Differential Equation (PF-ODE) with an initial value $x_t$ yields an effective posterior sample $p_θ(X_0|X_t=x_t)$. Based on this observation, we adopt the Consistency Model (CM), which is distilled from PF-ODE, for posterior sampling. Furthermore, we design a novel family of DIS using only CM. Through extensive experiments, we show that our proposed method for posterior sample approximation substantially enhance the effectiveness of DIS for neural network operators $f(\cdot)$ (e.g., in semantic segmentation). Additionally, our experiments demonstrate the effectiveness of the new CM-based inversion techniques. The source code is provided in the supplementary material.

cs.CV↗

Impact of local CP-odd domain in hot QCD on axionic domain-wall interpretation for NANOGrav 15-year Data

We argue that the axionic domain-wall with a QCD bias may be incompatible with the NANOGrav 15-year data on a stochastic gravitational wave (GW) background, when the domain wall network collapses in the hot-QCD induced local CP-odd domain. This is due to the drastic suppression of the QCD bias set by the QCD topological susceptibility in the presence of the CP-odd domain with nonzero $θ$ parameter of order one which the QCD sphaleron could generate. We quantify the effect on the GW signals by working on a low-energy effective model of Nambu-Jona-Lasinio type in the mean field approximation. We find that only at $θ=π$, the QCD bias tends to get significantly large enough due to the criticality of the thermal CP restoration, which would, however, give too big signal strengths to be consistent with the NANOGrav 15-year data and would also be subject to the strength of the phase transition at the criticality.

hep-ph↗

GlobalBuildingMap -- Unveiling the Mystery of Global Buildings

Understanding how buildings are distributed globally is crucial to revealing the human footprint on our home planet. This built environment affects local climate, land surface albedo, resource distribution, and many other key factors that influence well-being and human health. Despite this, quantitative and comprehensive data on the distribution and properties of buildings worldwide is lacking. To this end, by using a big data analytics approach and nearly 800,000 satellite images, we generated the highest resolution and highest accuracy building map ever created: the GlobalBuildingMap (GBM). A joint analysis of building maps and solar potentials indicates that rooftop solar energy can supply the global energy consumption need at a reasonable cost. Specifically, if solar panels were placed on the roofs of all buildings, they could supply 1.1-3.3 times -- depending on the efficiency of the solar device -- the global energy consumption in 2020, which is the year with the highest consumption on record. We also identified a clear geospatial correlation between building areas and key socioeconomic variables, which indicates our global building map can serve as an important input to modeling global socioeconomic needs and drivers.

cs.CV↗

On the Foundations of Earth and Climate Foundation Models

Foundation models have enormous potential in advancing Earth and climate sciences, however, current approaches may not be optimal as they focus on a few basic features of a desirable Earth and climate foundation model. Crafting the ideal Earth foundation model, we define eleven features which would allow such a foundation model to be beneficial for any geoscientific downstream application in an environmental- and human-centric manner.We further shed light on the way forward to achieve the ideal model and to evaluate Earth foundation models. What comes after foundation models? Energy efficient adaptation, adversarial defenses, and interpretability are among the emerging directions.

cs.AI↗

Exploring the compactness of $α$ cluster in $^{16}$O nuclei with relativistic $^{16}$O+$^{16}$O collisions

Probing the $α$ cluster of $^{16}$O with the relativistic $^{16}$O+$^{16}$O collisions has raised great interest in the heavy ion community. However, the effects of the $α$ cluster on the soft hadron observables vary largely among different studies. In this paper, we explain the differences by the compactness of the $α$ cluster in oxygen, using iEBE-VISHNU hydrodynamic simulations with different initial state $α$ cluster configurations. We also find several observables, such as the intensive skewness of the $[p_{\rm T}]$ correlator $Γ_{p_{\rm T}}$, the harmonic flows $v_2\{2\}$, $v_2\{4\}$, $v_3\{2\}$, and the $v_n^2-δ[p_{\rm T}]$ correlations $ρ(v_{2}^{2}, [p_{\rm T}])$, $ρ(v_{3}^{2}, [p_{\rm T}])$ in $^{16}$O+$^{16}$O collisions are sensitive to the compactness of the $α$ cluster in the colliding nuclei, which can be used to constrain the configurations of $^{16}$O in the future. Our study serves as an important step toward the quantitative exploration of the $α$ cluster configuration in the light nuclei with relativistic heavy ion collisions.

nucl-th↗

Holmes: Towards Distributed Training Across Clusters with Heterogeneous NIC Environment

Large language models (LLMs) such as GPT-3, OPT, and LLaMA have demonstrated remarkable accuracy in a wide range of tasks. However, training these models can incur significant expenses, often requiring tens of thousands of GPUs for months of continuous operation. Typically, this training is carried out in specialized GPU clusters equipped with homogeneous high-speed Remote Direct Memory Access (RDMA) network interface cards (NICs). The acquisition and maintenance of such dedicated clusters is challenging. Current LLM training frameworks, like Megatron-LM and Megatron-DeepSpeed, focus primarily on optimizing training within homogeneous cluster settings. In this paper, we introduce Holmes, a training framework for LLMs that employs thoughtfully crafted data and model parallelism strategies over the heterogeneous NIC environment. Our primary technical contribution lies in a novel scheduling method that intelligently allocates distinct computational tasklets in LLM training to specific groups of GPU devices based on the characteristics of their connected NICs. Furthermore, our proposed framework, utilizing pipeline parallel techniques, demonstrates scalability to multiple GPU clusters, even in scenarios without high-speed interconnects between nodes in distinct clusters. We conducted comprehensive experiments that involved various scenarios in the heterogeneous NIC environment. In most cases, our framework achieves performance levels close to those achievable with homogeneous RDMA-capable networks (InfiniBand or RoCE), significantly exceeding training efficiency within the pure Ethernet environment. Additionally, we verified that our framework outperforms other mainstream LLM frameworks under heterogeneous NIC environment in terms of training efficiency and can be seamlessly integrated with them.

cs.CL↗

Significantly Enhanced Vacancy Diffusion in Mn-containing Alloys

Manipulating point defects for tailored macroscopic properties remains a formidable challenge in materials science. This study demonstrates a proof-of-principle for a universal law involving element Mn, significantly enhancing vacancy diffusion through an unprecedented anomalous Friedel Oscillations phenomenon, across most metals in the periodic table. The correlation between Mn-induced point-defect dynamic changes and intrinsic macro-properties is robustly validated through the first-principles theory and well-designed experiments. The physical origin stems from Mn's exceptionally large effective intra-elemental 3d electron interactions, surpassing the Coulomb attraction induced by vacancy and disrupting the electron screening effect. Given the ubiquitous nature of vacancies and their recognition as the most crucial defects influencing nearly all physical and mechanical properties of crystalline materials, this outcome may drive advances in a broad domain.

cond-mat.mtrl-sci↗

Generator Identification for Linear SDEs with Additive and Multiplicative Noise

In this paper, we present conditions for identifying the generator of a linear stochastic differential equation (SDE) from the distribution of its solution process with a given fixed initial state. These identifiability conditions are crucial in causal inference using linear SDEs as they enable the identification of the post-intervention distributions from its observational distribution. Specifically, we derive a sufficient and necessary condition for identifying the generator of linear SDEs with additive noise, as well as a sufficient condition for identifying the generator of linear SDEs with multiplicative noise. We show that the conditions derived for both types of SDEs are generic. Moreover, we offer geometric interpretations of the derived identifiability conditions to enhance their understanding. To validate our theoretical results, we perform a series of simulations, which support and substantiate the established findings.

math.ST↗

USFM: A Universal Ultrasound Foundation Model Generalized to Tasks and Organs towards Label Efficient Image Analysis

Inadequate generality across different organs and tasks constrains the application of ultrasound (US) image analysis methods in smart healthcare. Building a universal US foundation model holds the potential to address these issues. Nevertheless, the development of such foundational models encounters intrinsic challenges in US analysis, i.e., insufficient databases, low quality, and ineffective features. In this paper, we present a universal US foundation model, named USFM, generalized to diverse tasks and organs towards label efficient US image analysis. First, a large-scale Multi-organ, Multi-center, and Multi-device US database was built, comprehensively containing over two million US images. Organ-balanced sampling was employed for unbiased learning. Then, USFM is self-supervised pre-trained on the sufficient US database. To extract the effective features from low-quality US images, we proposed a spatial-frequency dual masked image modeling method. A productive spatial noise addition-recovery approach was designed to learn meaningful US information robustly, while a novel frequency band-stop masking learning approach was also employed to extract complex, implicit grayscale distribution and textural variations. Extensive experiments were conducted on the various tasks of segmentation, classification, and image enhancement from diverse organs and diseases. Comparisons with representative US image analysis models illustrate the universality and effectiveness of USFM. The label efficiency experiments suggest the USFM obtains robust performance with only 20% annotation, laying the groundwork for the rapid development of US models in clinical practices.

eess.IV↗

Exploring the partonic collectivity in small systems at the LHC

Using the Hydro-Coal-Frag model that combines hydrodynamics at low $p_{\rm T}$, quark coalescence at intermediate $p_{\rm T}$, and the LBT transport model at high $p_{\rm T}$, we study the spectra and elliptic flow of identified hadrons in high multiplicity p--Pb and p--p collisions at the Large Hadron Collider (LHC). In p--Pb collisions, the Hydro-Coal-Frag model gives a good description of the differential elliptic flow over the $p_{\rm T}$ range from 0 to 6 GeV and the approximate number of constituent quark (NCQ) scaling at intermediate $p_{\rm T}$. Although Hydro-Coal-Frag model can also roughly describe the elliptic flow in high multiplicity p--p collisions with the quark coalescence process, the larger contribution from the string fragmentations leads to a notable violation of the NCQ scaling of $v_2$ at intermediate $p_{\rm T}$ as observed in the experiment. Comparison runs of the Hydro-Frag model without the coalescence process demonstrate that regardless the parameter adjustments, the Hydro-Frag model cannot simultaneously describe the $p_{\rm T}$ spectra and the elliptic flow of identified hadrons in either p--Pb collisions or p--p collisions. The calculations in this paper thus provide support for the existence of partonic degrees of freedom and the possible formation of the QGP in the small systems created at the LHC.

nucl-th↗