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Yuhang Tan

Publications and source records attributed to Yuhang Tan.

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Laboratory X-ray Microscopy Using Fresnel Zone Plate: Method and Practice

This book was written to share our experience in developing a Fresnel zone plate (FZP) based X-ray microscope. The research began in September 2020, when we were going to build such a scientific imaging instrument from scratch in our laboratory. At that time, we could not find a textbook that systematically explained the entire development process step by step. We therefore had to make progress through trials and mistakes. After nearly five years of hard effort, we finally managed to build such an X-ray microscope in April 2025. Through this experience, we came to realize how challenging it can be to develop a new FZP-based X-ray microscope without systematic guidance. We therefore believe that it is worthwhile to share the learned lessons with readers who may be interested in developing their own FZP-based X-ray microscopes in the future. I would encourage readers to treat this book as a practical manual rather than a traditional textbook. Readers are not expected to be experts in X-ray imaging. Instead, a basic background in college-level physics should be sufficient to understand most of the material. Inevitably, the current edition has limitations and may contain omissions or inaccuracies due to the authors' limited experience and perspective. I sincerely welcome comments, suggestions and discussions from readers, please feel free to contact me at geyongshuai1987@qq.com. Your feedback will be greatly appreciated and will help make future editions of this book more complete.

physics.optics

CBCT scatter correction with dual-layer flat-panel detector

Background: Recently, the popularity of dual-layer flat-panel detector (DL-FPD) based dual-energy cone-beam CT (DE-CBCT) imaging has been increasing. However, the image quality of DE-CBCT remains constrained by the Compton scattered X-ray photons. Purpose: The objective of this study is to develop an energy-modulated scatter correction method for DL-FPD based CBCT imaging. Methods: In DL-FPD, a certain portion of the X-ray photons (mainly low-energy primary and scattered photons) passing through the object are captured by the top detector layer, while the remaining X-ray photons (mainly high-energy primary and scattered photons) are collected by the bottom detector layer. Based on the two set of distinct low-energy and high-energy measurements, a linear signal model was approximated for the dual-energy primary and scattered signals on DL-FPD. The distributions of X-ray scatters were quickly estimated using this signal model. Monte Carlo (MC) simulation of a water phantom was conducted to verify this newly developed scatter estimation method. Moreover, physical experiments of water phantom, head phantom, and abdominal phantom were carried out to validate the real performance of this proposed scatter correction method. Results: The MC results showed that the e-Grid method was able to generate scatter distributions close to the ground truth. Moreover, the physical experiments demonstrated that the e-Grid method can greatly reduce the shading artifacts in both low-energy and high-energy CBCT images acquired from DL-FPD. On average, the image non-uniformity (NU) was reduced by over 77% in the low-energy CBCT image and by over 66% in the high-energy CBCT image. A a consequence, the accuracy of the decomposed multi-material bases was substantially improved.

physics.med-ph

Explanations of MTF discrepancy in grating-based X-ray differential phase contrast CT imaging

As a multi-contrast X-ray computed tomography (CT) imaging system, the grating-based Talbot-Lau interferometer is able to generate the absorption contrast and differential phase contrast (DPC) images concurrently. However, experiments found that the absorption CT (ACT) images have better spatial resolution, i.e., higher modulation transfer function (MTF), than the differential phase contrast CT (DPCT) images. Until now, the root cause of such observed discrepancy has not been rigorously investigated. Through physical experiments, this study revealed that the phase grating in the Talbot-Lau interferometer induces direct superposition of paired split absorption signals and inverse superposition of paired split phase signals via diffraction. Further simulation experiments demonstrated that this splitting leads to a reduction in MTF in both ACT and DPCT images, with distinct superposition mechanisms contributing to the lower MTF in DPCT. Besides, such MTF discrepancy may also be affected in a minor extent by object composition, sample size, beam spectra and detector pixel size. Based on this study, the spatial resolution could be optimized when designing a grating-based DPC imaging system.

physics.med-ph

Model-driven CT reconstruction algorithm for nano-resolution X-ray phase contrast imaging

The low-density imaging performance of a zone plate based nano-resolution hard X-ray computed tomography (CT) system can be significantly improved by incorporating a grating-based Lau interferometer. Due to the diffraction, however, the acquired nano-resolution phase signal may suffer splitting problem, which impedes the direct reconstruction of phase contrast CT (nPCT) images. To overcome, a new model-driven nPCT image reconstruction algorithm is developed in this study. In it, the diffraction procedure is mathematically modeled into a matrix B, from which the projections without signal splitting can be generated invertedly. Furthermore, a penalized weighed least-square model with total variation (PWLS-TV) is employed to denoise these projections, from which nPCT images with high accuracy are directly reconstructed. Numerical and physical experiments demonstrate that this new algorithm is able to work with phase projections having any splitting distances. Results also reveal that nPCT images with higher signal-to-noise-ratio (SNR) would be reconstructed from projections with larger signal splittings. In conclusion, a novel model-driven nPCT image reconstruction algorithm with high accuracy and robustness is verified for the Lau interferometer based hard X-ray nano-resolution phase contrast imaging.

eess.IV

Super resolution dual-layer CBCT imaging with model-guided deep learning

Objective: This study aims at investigating a novel super resolution CBCT imaging technique with the dual-layer flat panel detector (DL-FPD). Approach: In DL-FPD based CBCT imaging, the low-energy and high-energy projections acquired from the top and bottom detector layers contain intrinsically mismatched spatial information, from which super resolution CBCT images can be generated. To explain, a simple mathematical model is established according to the signal formation procedure in DL-FPD. Next, a dedicated recurrent neural network (RNN), named as suRi-Net, is designed by referring to the above imaging model to retrieve the high resolution dual-energy information. Different phantom experiments are conducted to validate the performance of this newly developed super resolution CBCT imaging method. Main Results: Results show that the proposed suRi-Net can retrieve high spatial resolution information accurately from the low-energy and high-energy projections having lower spatial resolution. Quantitatively, the spatial resolution of the reconstructed CBCT images of the top and bottom detector layers is increased by about 45% and 54%, respectively. Significance: In future, suRi-Net provides a new approach to achieve high spatial resolution dual-energy imaging in DL-FPD based CBCT systems.

physics.med-ph

Super resolution dual-energy cone-beam CT imaging with dual-layer flat-panel detector

For medical cone-beam computed tomography (CBCT) imaging, the native receptor array of the flat-panel detector (FPD) is usually binned into a reduced matrix size. By doing so, the signal readout speed can be increased by over 4-9 times at the expense of sacrificing the spatial resolution by at least 50%-67%. Clearly, such tradition poses a main bottleneck in generating high spatial resolution and high temporal resolution CBCT images at the same time. In addition, the conventional FPD is also difficult in generating dual-energy CBCT images. In this paper, we propose an innovative super resolution dual-energy CBCT imaging method, named as suRi, based on dual-layer FPD (DL-FPD) to overcome these aforementioned difficulties at once. With suRi, specifically, an 1D or 2D sub-pixel (half pixel in this study) shifted binning is applied to replace the conventionally aligned binning to double the spatial sampling rate during the dual-energy data acquisition. As a result, the suRi approach provides a new strategy to enable high signal readout speed and high spatial resolution CBCT imaging with FPD. Moreover, a penalized likelihood material decomposition algorithm is developed to directly reconstruct the high resolution bases from the dual-energy CBCT projections containing spatial sub-pixel shifts. Experiments based on the single-layer FPD and DL-FPD are performed with physical phantoms and biological specimen to validate this newly developed suRi method. The synthesized monochromatic CT imaging results demonstrate that suRi can significantly improve the spatial image resolution by 46.15%. We believe the developed suRi method would be capable to greatly enhance the imaging performance of the DL-FPD based dual-energy CBCT systems in future.

physics.med-ph

Leakage current simulations of Low Gain Avalanche Diode with improved Radiation Damage Modeling

We report precise TCAD simulations of IHEP-IME-v1 Low Gain Avalanche Diode (LGAD) calibrated by secondary ion mass spectroscopy (SIMS). Our setup allows us to evaluate the leakage current, capacitance, and breakdown voltage of LGAD, which agree with measurements' results before irradiation. And we propose an improved LGAD Radiation Damage Model (LRDM) which combines local acceptor removal with global deep energy levels. The LRDM is applied to the IHEP-IME-v1 LGAD and able to predict the leakage current well at -30 $^{\circ}$C after an irradiation fluence of $ Φ_{eq}=2.5 \times 10^{15} ~n_{eq}/cm^{2}$. The charge collection efficiency (CCE) is under development.

physics.ins-det

Simulation of the 4H-SiC Low Gain Avalanche Diode

Silicon Carbide device (4H-SiC) has potential radiation hardness, high saturated carrier velocity and low temperature sensitivity theoretically. The Silicon Low Gain Avalanche Diode (LGAD) has been verified to have excellent time performance. Therefore, the 4H-SiC LGAD is introduced in this work for application to detect the Minimum Ionization Particles (MIPs). We provide guidance to determine the thickness and doping level of the gain layer after an analytical analysis. The gain layer thickness $d_{gain}=0.5~μm$ is adopted in our design. We design two different types of 4H-SiC LGAD which have two types electric field, and the corresponding leakage current, capacitance and gain are simulated by TCAD tools. Through analysis of the simulation results, the advantages and disadvantages are discussed for two types of 4H-SiC LGAD.

physics.ins-det

Design and testing of LGAD sensor with shallow carbon implantation

The low gain avalanche detectors (LGADs) are thin sensors with fast charge collection which in combination with internal gain deliver an outstanding time resolution of about 30 ps. High collision rates and consequent large particle rates crossing the detectors at the upgraded Large Hadron Collider (LHC) in 2028 will lead to radiation damage and deteriorated performance of the LGADs. The main consequence of radiation damage is loss of gain layer doping (acceptor removal) which requires an increase of bias voltage to compensate for the loss of charge collection efficiency and consequently time resolution. The Institute of High Energy Physics (IHEP), Chinese Academy of Sciences (CAS) has developed a process based on the Institute of Microelectronics (IME), CAS capability to enrich the gain layer with carbon to reduce the acceptor removal effect by radiation. After 1 MeV neutron equivalent fluence of 2.5$\times$10$^{15}$ n$_{eq}$/cm$^{2}$, which is the maximum fluence to which sensors will be exposed at ATLAS High Granularity Timing Detector (HGTD), the IHEP-IME second version (IHEP-IMEv2) 50 $μ$m LGAD sensors already deliver adequate charge collection > 4 fC and time resolution < 50 ps at voltages < 400 V. The operation voltages of these 50 $μ$m devices are well below those at which single event burnout may occur.

physics.ins-det

Time Resolution of the 4H-SiC PIN Detector

We address the determination of the time resolution for the $\rm 100~μm$ 4H-SiC PIN detectors fabricated by Nanjing University (NJU). The time response to $\rm β$ particles from a $\rm ^{90}$Sr source is investigated for the detection of the minimum ionizing particles (MIPs). We study the influence of different reverse voltages, which correspond to different carrier velocities and device sizes, and how this correlates with the detector capacitance. We determine a time resolution $\rm (94\pm1)~ps$ for $\rm 100~μm$ 4H-SiC PIN detector. A fast simulation software, termed RASER (RAdiation SEmiconductoR), is developed, and validated by comparing the waveform obtained from simulated and measured data. The simulated time resolution is $\rm (73\pm 1)~ps$ after considering the intrinsic leading contributions of the detector to time resolution.

physics.ins-det

Timing performance simulation for 3D 4H-SiC detector

To meet high radiation challenge for detectors in future high-energy physics, a novel 3D 4H-SiC detector was investigated. SiC detectors could potentially operate in radiation harsh and room temperature environment because of its high thermal conductivity and high atomic displacement threshold energy. 3D structure, which decouples thickness and distance between electrodes, further improves timing performance and radiation hardness of the detector. We developed a simulation software - RASER (RAdiation SEmiconductoR) to simulate the time resolution of planar and 3D 4H-SiC detectors with different parameters and structures, and the reliability of the software is verified by comparing time resolution results of simulation with data. The rough time resolution of 3D 4H-SiC detector was estimated, and the simulation parameters could be used as guideline to 3D 4H-SiC detector design and optimization.

physics.ins-det

Effects of shallow carbon and deep N++ layer on the radiation hardness of IHEP-IME LGAD sensors

Low Gain Avalanche Diode (LGAD) is applied for the High-Granularity Timing Detector (HGTD), and it will be used to upgrade the ATLAS experiment. The first batch IHEP-IME LGAD sensors were designed by the Institute of High Energy Physics (IHEP) and fabricated by the Institute of Microelectronics (IME). Three IHEP-IME sensors (W1, W7 and W8) were irradiated by the neutrons up to the fluence of 2.5 x 10^15 n_eq/cm^2 to study the effect of the shallow carbon and deep N++ layer on the irradiation hardness. Taking W7 as a reference, W1 has an extra shallow carbon applied, and W8 has a deeper N++ layer.

physics.ins-det

The performance of IHEP-NDL LGAD sensors after neutron irradiation

The performances of Low Gain Avalanche diode (LGAD) sensors from a neutron irradiation campaign with fluences of 0.8 x 10^15, 15 x 10^15 and 2.5 x 10^15 neq/cm2 are reported in this article. These LGAD sensors are developed by the Institute of High Energy Physics, Chinese Academy of Sciences and the Novel Device Laboratory for the High Granularity Timing Detector of the High Luminosity Large Hadron Collider. The timing resolution and collected charge of the LGAD sensors were measured with electrons from a beta source. After irradiation with a fluence of 2.5 x 10^15 neq/cm2, the collected charge decreases from 40 fC to 7 fC, the signal-to-noise ratio deteriorates from 48 to 12, and the timing resolution increases from 29 ps to 39 ps.

physics.ins-det

Radiation effects on NDL prototype LGAD sensors after proton irradiation

We study the radiation effects of the Low Gain Avalanche Detector (LGAD) sensors developed by the Institute of High Energy Physics (IHEP) and the Novel Device Laboratory (NDL) of Beijing Normal University in China. These new sensors have been irradiated at the China Institute of Atomic Energy (CIAE) using 100 MeV proton beam with five different fluences from 7$\times10^{14}$ $n_{eq}/cm^2$ up to 4.5$\times10^{15}$ $n_{eq}/cm^2$. The result shows the effective doping concentration in the gain layer decreases with the increase of irradiation fluence, as expected by the acceptor removal mechanism. By comparing data and model gives the acceptor removal coefficient $c_{A}$ = $(6.07\pm0.70)\times10^{-16}~cm^2$, which indicates the NDL sensor has fairly good radiation resistance.

physics.ins-det

Search for invisible decay of a Higgs boson produced at the CEPC

The existence of dark matter has been established in astrophysics. However, there is no candidate for DM in the Stand Model (SM). In SM, the Higgs boson can only decay invisibly via $H\rightarrow ZZ^\ast \rightarrow ν\barνν\barν$ or DM, so any evidence of invisible Higgs decay that exceeds BR (H$\rightarrow$inv.) will immediately point to a phenomenon that is beyond the standard model (BSM). In this paper, we report on the upper limit of BR (H$\rightarrow$invisible) estimated for three channels, including two leptonic channels and one hadronic channel, under the assumption predicted by SM. With the SM ZH production rate, the upper limit of BR (H$\rightarrow$inv.) could reach 0.24\% at the 95\% confidence level.

hep-ex

Charaterization of the first prototype IHEP-NDL LGAD sensor

The timing measurement of charged particles using silicon detector is widely used in synchrotron source as X-ray detectors, in time-of-flight mass spectrometer and especially in large collider experiment. To reduce the drastically event pile-up of high-luminosity large hadron collider (HL-LHC), a new concept of 4-dimension detector including timing and positon has been proposed. One of the candidates for the 4-dimension detector is a new kind of silicon detector called Low Gain Avalanche Diode (LGAD). In China, Institute of High Energy Physics (IHEP) Chinese Academic Science cooperated with Novel Device Laboratory (NDL) at Beijing Normal University have fabricated a series of LGAD sensors. The characterization of the first prototype of IHEP-NDL sensors is presented including leakage current and sensor capacitance measurement. A test system for the time resolution of jitter term using pico-second laser and fast sampling rate oscilloscope is also setup, and the time resolution of 10 ps can be achieved with these sensors.

physics.ins-det