arXiv subjects

Yunxiang Li

Publications and source records attributed to Yunxiang Li.

At least 19 recordsLinked to original sources

arXiv2026

An integrated diffusion-weighted imaging processing and interpretation platform for MR-guided radiotherapy

Background: Magnetic resonance imaging-guided linear accelerators (MR-Linacs) allow diffusion-weighted imaging (DWI) to be acquired at every treatment fraction, but converting these low-signal-to-noise-ratio acquisitions into clinical decisions requires both reliable quantitative processing and an interpretation that reconciles a scattered and often contradictory literature. Purpose: To describe and evaluate an integrated, web-based platform that carries raw MR-Linac DWI to a structured, literature-grounded clinical interpretation, and to assess its retrieval-augmented generation (RAG) interpretation module by independent expert rating. Methods: The platform couples a deep-learning processing pipeline, comprising distortion correction, denoising, and intravoxel incoherent motion (IVIM)/apparent diffusion coefficient (ADC) fitting, with longitudinal region-of-interest analysis and a RAG interpretation agent. The agent reasons over a two-layer knowledge base of curated publications (a structured catalog index plus line-indexed full text), delegates arithmetic to deterministic tools, and is designed to trace each statement to a source document, section, and line range. One medical physicist and one physician independently rated the agent's reports for nine longitudinal glioblastoma cases on a 1-5 scale across three metrics: clinical-reasoning soundness, literature-citation quality, and overall clinical utility. Results: Across 54 ratings, the pooled mean was 4.65 +/- 0.80, with 93% of ratings >= 4; metric means were 4.6 (reasoning), 4.5 (citation), and 4.8 (utility), and raters agreed within one point on 85% of paired ratings. Conclusions: A single platform can integrate MR-Linac DWI post-processing with traceable, expert-evaluated clinical interpretation, while highlighting the safeguards needed to verify LLM-generated reasoning in radiation oncology.

physics.med-ph↗

arXiv2026

Towards Parameter-Free Temporal Difference Learning

Temporal difference (TD) learning is a fundamental algorithm for estimating value functions in reinforcement learning. Recent finite-time analyses of TD with linear function approximation quantify its theoretical convergence rate. However, they often require setting the algorithm parameters using problem-dependent quantities that are difficult to estimate in practice -- such as the minimum eigenvalue of the feature covariance ($ω$) or the mixing time of the underlying Markov chain ($τ_{\text{mix}}$). In addition, some analyses rely on nonstandard and impractical modifications, exacerbating the gap between theory and practice. To address these limitations, we use an exponential step-size schedule with the standard TD(0) algorithm. We analyze the resulting method under two sampling regimes: independent and identically distributed (i.i.d.) sampling from the stationary distribution, and the more practical Markovian sampling along a single trajectory. In the i.i.d.\ setting, the proposed algorithm does not require knowledge of problem-dependent quantities such as $ω$, and attains the optimal bias-variance trade-off for the last iterate. In the Markovian setting, we propose a regularized TD(0) algorithm with an exponential step-size schedule. The resulting algorithm achieves a comparable convergence rate to prior works, without requiring projections, iterate averaging, or knowledge of $τ_{\text{mix}}$ or $ω$.

cs.LG↗

arXiv2026

TreePS-RAG: Tree-based Process Supervision for Reinforcement Learning in Agentic RAG

Agentic retrieval-augmented generation (RAG) formulates question answering as a multi-step interaction between reasoning and information retrieval, and has recently been advanced by reinforcement learning (RL) with outcome-based supervision. While effective, relying solely on sparse final rewards limits step-wise credit assignment and provides weak guidance for intermediate reasoning and actions. Recent efforts explore process-level supervision, but typically depend on offline constructed training data, which risks distribution shift, or require costly intermediate annotations. We present TreePS-RAG, an online, tree-based RL framework for agentic RAG that enables step-wise credit assignment while retaining standard outcome-only rewards. Our key insight is to model agentic RAG reasoning as a rollout tree, where each reasoning step naturally maps to a node. This tree structure allows step utility to be estimated via Monte Carlo estimation over its descendant outcomes, yielding fine-grained process advantages without requiring intermediate labels. To make this paradigm practical, we introduce an efficient online tree construction strategy that preserves exploration diversity under a constrained computational budget. With a rollout cost comparable to strong baselines like Search-R1, experiments on seven multi-hop and general QA benchmarks across multiple model scales show that TreePS-RAG consistently and significantly outperforms both outcome-supervised and leading process-supervised RL methods.

cs.CL↗

arXiv2026

Scale-aware Adaptive Supervised Network with Limited Medical Annotations

Medical image segmentation faces critical challenges in semi-supervised learning scenarios due to severe annotation scarcity requiring expert radiological knowledge, significant inter-annotator variability across different viewpoints and expertise levels, and inadequate multi-scale feature integration for precise boundary delineation in complex anatomical structures. Existing semi-supervised methods demonstrate substantial performance degradation compared to fully supervised approaches, particularly in small target segmentation and boundary refinement tasks. To address these fundamental challenges, we propose SASNet (Scale-aware Adaptive Supervised Network), a dual-branch architecture that leverages both low-level and high-level feature representations through novel scale-aware adaptive reweight mechanisms. Our approach introduces three key methodological innovations, including the Scale-aware Adaptive Reweight strategy that dynamically weights pixel-wise predictions using temporal confidence accumulation, the View Variance Enhancement mechanism employing 3D Fourier domain transformations to simulate annotation variability, and segmentation-regression consistency learning through signed distance map algorithms for enhanced boundary precision. These innovations collectively address the core limitations of existing semi-supervised approaches by integrating spatial, temporal, and geometric consistency principles within a unified optimization framework. Comprehensive evaluation across LA, Pancreas-CT, and BraTS datasets demonstrates that SASNet achieves superior performance with limited labeled data, surpassing state-of-the-art semi-supervised methods while approaching fully supervised performance levels. The source code for SASNet is available at https://github.com/HUANGLIZI/SASNet.

eess.IV↗

arXiv2025

Multi-directional Safe Rectangle Corridor-Based MPC for Nonholonomic Robots Navigation in Cluttered Environment

Autonomous Mobile Robots (AMRs) have become indispensable in industrial applications due to their operational flexibility and efficiency. Navigation serves as a crucial technical foundation for accomplishing complex tasks. However, navigating AMRs in dense, cluttered, and semi-structured environments remains challenging, primarily due to nonholonomic vehicle dynamics, interactions with mixed static/dynamic obstacles, and the non-convex constrained nature of such operational spaces. To solve these problems, this paper proposes an Improved Sequential Model Predictive Control (ISMPC) navigation framework that systematically reformulates navigation tasks as sequential switched optimal control problems. The framework addresses the aforementioned challenges through two key innovations: 1) Implementation of a Multi-Directional Safety Rectangular Corridor (MDSRC) algorithm, which encodes the free space through rectangular convex regions to avoid collision with static obstacles, eliminating redundant computational burdens and accelerating solver convergence; 2) A sequential MPC navigation framework that integrates corridor constraints with barrier function constraints is proposed to achieve static and dynamic obstacle avoidance. The ISMPC navigation framework enables direct velocity generation for AMRs, simplifying traditional navigation algorithm architectures. Comparative experiments demonstrate the framework's superiority in free-space utilization ( an increase of 41.05$\%$ in the average corridor area) while maintaining real-time computational performance (average corridors generation latency of 3 ms).

cs.RO↗

arXiv2025

A Conditional Point Cloud Diffusion Model for Deformable Liver Motion Tracking Via a Single Arbitrarily-Angled X-ray Projection

Deformable liver motion tracking using a single X-ray projection enables real-time motion monitoring and treatment intervention. We introduce a conditional point cloud diffusion model-based framework for accurate and robust liver motion tracking from arbitrarily angled single X-ray projections (PCD-Liver), which estimates volumetric liver motion by solving deformable vector fields (DVFs) of a prior liver surface point cloud based on a single X-ray image. The model is patient-specific and consists of two main components: a rigid alignment model to estimate the liver's overall shifts and a conditional point cloud diffusion model that further corrects for liver surface deformations. Conditioned on motion-encoded features extracted from a single X-ray projection via a geometry-informed feature pooling layer, the diffusion model iteratively solves detailed liver surface DVFs in a projection angle-agnostic manner. The liver surface motion estimated by PCD-Liver serves as a boundary condition for a U-Net-based biomechanical model to infer internal liver motion and localize liver tumors. A dataset of ten liver cancer patients was used for evaluation. The accuracy of liver point cloud motion estimation was assessed using root mean square error (RMSE) and 95th-percentile Hausdorff distance (HD95), while liver tumor localization error was quantified using center-of-mass error (COME). The mean (standard deviation) RMSE, HD95, and COME of the prior liver or tumor before motion estimation were 8.82(3.58) mm, 10.84(4.55) mm, and 9.72(4.34) mm, respectively. After PCD-Liver motion estimation, the corresponding values improved to 3.63(1.88) mm, 4.29(1.75) mm, and 3.46(2.15) mm. Under highly noisy conditions, PCD-Liver maintained stable performance. This study presents an accurate and robust framework for deformable liver motion estimation and tumor localization in image-guided radiotherapy.

physics.med-ph↗

arXiv2025

RAG-Zeval: Towards Robust and Interpretable Evaluation on RAG Responses through End-to-End Rule-Guided Reasoning

Robust evaluation is critical for deploying trustworthy retrieval-augmented generation (RAG) systems. However, current LLM-based evaluation frameworks predominantly rely on directly prompting resource-intensive models with complex multi-stage prompts, underutilizing models' reasoning capabilities and introducing significant computational cost. In this paper, we present RAG-Zeval (RAG-Zero Evaluator), a novel end-to-end framework that formulates faithfulness and correctness evaluation as a rule-guided reasoning task. Our approach trains evaluators with reinforcement learning, facilitating compact models to generate comprehensive and sound assessments with detailed explanation in one-pass. We introduce a ranking-based outcome reward mechanism, using preference judgments rather than absolute scores, to address the challenge of obtaining precise pointwise reward signals. To this end, we synthesize the ranking references by generating quality-controlled responses with zero human annotation. Experiments demonstrate RAG-Zeval's superior performance, achieving the strongest correlation with human judgments and outperforming baselines that rely on LLMs with 10-100 times more parameters. Our approach also exhibits superior interpretability in response evaluation.

cs.CL↗

arXiv2025

ReMA: Learning to Meta-think for LLMs with Multi-Agent Reinforcement Learning

Recent research on Reasoning of Large Language Models (LLMs) has sought to further enhance their performance by integrating meta-thinking -- enabling models to monitor, evaluate, and control their reasoning processes for more adaptive and effective problem-solving. However, current single-agent work lacks a specialized design for acquiring meta-thinking, resulting in low efficacy. To address this challenge, we introduce Reinforced Meta-thinking Agents (ReMA), a novel framework that leverages Multi-Agent Reinforcement Learning (MARL) to elicit meta-thinking behaviors, encouraging LLMs to think about thinking. ReMA decouples the reasoning process into two hierarchical agents: a high-level meta-thinking agent responsible for generating strategic oversight and plans, and a low-level reasoning agent for detailed executions. Through iterative reinforcement learning with aligned objectives, these agents explore and learn collaboration, leading to improved generalization and robustness. Empirical results from single-turn experiments demonstrate that ReMA outperforms single-agent RL baselines on complex reasoning tasks, including competitive-level mathematical benchmarks and LLM-as-a-Judge benchmarks. Additionally, we further extend ReMA to multi-turn interaction settings, leveraging turn-level ratio and parameter sharing to improve efficiency. Comprehensive ablation studies further illustrate the evolving dynamics of each distinct agent, providing valuable insights into how the meta-thinking reasoning process enhances the reasoning capabilities of LLMs. Our code can be found in https://github.com/ziyuwan/ReMA-public

cs.AI↗

arXiv2025

STPNet: Scale-aware Text Prompt Network for Medical Image Segmentation

Accurate segmentation of lesions plays a critical role in medical image analysis and diagnosis. Traditional segmentation approaches that rely solely on visual features often struggle with the inherent uncertainty in lesion distribution and size. To address these issues, we propose STPNet, a Scale-aware Text Prompt Network that leverages vision-language modeling to enhance medical image segmentation. Our approach utilizes multi-scale textual descriptions to guide lesion localization and employs retrieval-segmentation joint learning to bridge the semantic gap between visual and linguistic modalities. Crucially, STPNet retrieves relevant textual information from a specialized medical text repository during training, eliminating the need for text input during inference while retaining the benefits of cross-modal learning. We evaluate STPNet on three datasets: COVID-Xray, COVID-CT, and Kvasir-SEG. Experimental results show that our vision-language approach outperforms state-of-the-art segmentation methods, demonstrating the effectiveness of incorporating textual semantic knowledge into medical image analysis. The code has been made publicly on https://github.com/HUANGLIZI/STPNet.

eess.IV↗

arXiv2025

Generate, Discriminate, Evolve: Enhancing Context Faithfulness via Fine-Grained Sentence-Level Self-Evolution

Improving context faithfulness in large language models is essential for developing trustworthy retrieval augmented generation systems and mitigating hallucinations, especially in long-form question answering (LFQA) tasks or scenarios involving knowledge conflicts. Existing methods either intervene LLMs only at inference without addressing their inherent limitations or overlook the potential for self-improvement. In this paper, we introduce GenDiE (Generate, Discriminate, Evolve), a novel self-evolving framework that enhances context faithfulness through fine-grained sentence-level optimization. GenDiE combines both generative and discriminative training, equipping LLMs with self-generation and self-scoring capabilities to facilitate iterative self-evolution. This supports both data construction for model alignment and score-guided search during inference. Furthermore, by treating each sentence in a response as an independent optimization unit, GenDiE effectively addresses the limitations of previous approaches that optimize at the holistic answer level, which may miss unfaithful details. Experiments on ASQA (in-domain LFQA) and ConFiQA (out-of-domain counterfactual QA) datasets demonstrate that GenDiE surpasses various baselines in both faithfulness and correctness, and exhibits robust performance for domain adaptation.

cs.CL↗

arXiv2025

SAMScore: A Content Structural Similarity Metric for Image Translation Evaluation

Image translation has wide applications, such as style transfer and modality conversion, usually aiming to generate images having both high degrees of realism and faithfulness. These problems remain difficult, especially when it is important to preserve content structures. Traditional image-level similarity metrics are of limited use, since the content structures of an image are high-level, and not strongly governed by pixel-wise faithfulness to an original image. To fill this gap, we introduce SAMScore, a generic content structural similarity metric for evaluating the faithfulness of image translation models. SAMScore is based on the recent high-performance Segment Anything Model (SAM), which allows content similarity comparisons with standout accuracy. We applied SAMScore on 19 image translation tasks, and found that it is able to outperform all other competitive metrics on all tasks. We envision that SAMScore will prove to be a valuable tool that will help to drive the vibrant field of image translation, by allowing for more precise evaluations of new and evolving translation models. The code is available at https://github.com/Kent0n-Li/SAMScore.

cs.CV↗

arXiv2025

Incomplete Data Multi-Source Static Computed Tomography Reconstruction with Diffusion Priors and Implicit Neural Representation

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and limited angle data in CT imaging, addressing these critical factors. This linear imaging inverse problem is solved by a conditional generation process within the denoising diffusion image reconstruction framework. The noisy volume data sample generated by the reverse time diffusion process is projected onto the affine set to ensure its consistency to the measured data. To enhance the quality of the reconstruction, the 3D phantom's orthogonal space projector is parameterized implicitly by a neural network. Then, a self-supervised learning algorithm is adopted to optimize the implicit neural representation. Through this multistage conditional generation process, we obtain a new approximate posterior sampling strategy for MSCT volume reconstruction. Numerical experiments are implemented with various imaging settings to verify the effectiveness of our methods for incomplete data MSCT volume reconstruction.

physics.med-ph↗

arXiv2024

Devising a Set of Compact and Explainable Spoken Language Feature for Screening Alzheimer's Disease

Alzheimer's disease (AD) has become one of the most significant health challenges in an aging society. The use of spoken language-based AD detection methods has gained prevalence due to their scalability due to their scalability. Based on the Cookie Theft picture description task, we devised an explainable and effective feature set that leverages the visual capabilities of a large language model (LLM) and the Term Frequency-Inverse Document Frequency (TF-IDF) model. Our experimental results show that the newly proposed features consistently outperform traditional linguistic features across two different classifiers with high dimension efficiency. Our new features can be well explained and interpreted step by step which enhance the interpretability of automatic AD screening.

cs.CL↗

arXiv2024

FDDM: Unsupervised Medical Image Translation with a Frequency-Decoupled Diffusion Model

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in achieving faithful image translations that can accurately preserve the anatomical structures of medical images, especially for unpaired datasets. The preservation of structural and anatomical details is essential to reliable medical diagnosis and treatment planning, as structural mismatches can lead to disease misidentification and treatment errors. In this study, we introduce the Frequency Decoupled Diffusion Model (FDDM) for MR-to-CT conversion. FDDM first obtains the anatomical information of the CT image from the MR image through an initial conversion module. This anatomical information then guides a subsequent diffusion model to generate high-quality CT images. Our diffusion model uses a dual-path reverse diffusion process for low-frequency and high-frequency information, achieving a better balance between image quality and anatomical accuracy. We extensively evaluated FDDM using public datasets for brain MR-to-CT and pelvis MR-to-CT translations, demonstrating its superior performance to other GAN-based, VAE-based, and diffusion-based models. The evaluation metrics included Frechet Inception Distance (FID), Peak Signal-to-Noise Ratio (PSNR), and Structural Similarity Index Measure (SSIM). FDDM achieved the best scores on all metrics for both datasets, particularly excelling in FID, with scores of 25.9 for brain data and 29.2 for pelvis data, significantly outperforming other methods. These results demonstrate that FDDM can generate high-quality target domain images while maintaining the accuracy of translated anatomical structures.

eess.IV↗

arXiv2024

FDNet: Feature Decoupled Segmentation Network for Tooth CBCT Image

Precise Tooth Cone Beam Computed Tomography (CBCT) image segmentation is crucial for orthodontic treatment planning. In this paper, we propose FDNet, a Feature Decoupled Segmentation Network, to excel in the face of the variable dental conditions encountered in CBCT scans, such as complex artifacts and indistinct tooth boundaries. The Low-Frequency Wavelet Transform (LF-Wavelet) is employed to enrich the semantic content by emphasizing the global structural integrity of the teeth, while the SAM encoder is leveraged to refine the boundary delineation, thus improving the contrast between adjacent dental structures. By integrating these dual aspects, FDNet adeptly addresses the semantic gap, providing a detailed and accurate segmentation. The framework's effectiveness is validated through rigorous benchmarks, achieving the top Dice and IoU scores of 85.28% and 75.23%, respectively. This innovative decoupling of semantic and boundary features capitalizes on the unique strengths of each element to elevate the quality of segmentation performance.

cs.CV↗

arXiv2024

Single-Point Supervised High-Resolution Dynamic Network for Infrared Small Target Detection

Infrared small target detection (IRSTD) tasks are extremely challenging for two main reasons: 1) it is difficult to obtain accurate labelling information that is critical to existing methods, and 2) infrared (IR) small target information is easily lost in deep networks. To address these issues, we propose a single-point supervised high-resolution dynamic network (SSHD-Net). In contrast to existing methods, we achieve state-of-the-art (SOTA) detection performance using only single-point supervision. Specifically, we first design a high-resolution cross-feature extraction module (HCEM), that achieves bi-directional feature interaction through stepped feature cascade channels (SFCC). It balances network depth and feature resolution to maintain deep IR small-target information. Secondly, the effective integration of global and local features is achieved through the dynamic coordinate fusion module (DCFM), which enhances the anti-interference ability in complex backgrounds. In addition, we introduce the high-resolution multilevel residual module (HMRM) to enhance the semantic information extraction capability. Finally, we design the adaptive target localization detection head (ATLDH) to improve detection accuracy. Experiments on the publicly available datasets NUDT-SIRST and IRSTD-1k demonstrate the effectiveness of our method. Compared to other SOTA methods, our method can achieve better detection performance with only a single point of supervision.

cs.CV↗

arXiv2024

STS MICCAI 2023 Challenge: Grand challenge on 2D and 3D semi-supervised tooth segmentation

Computer-aided design (CAD) tools are increasingly popular in modern dental practice, particularly for treatment planning or comprehensive prognosis evaluation. In particular, the 2D panoramic X-ray image efficiently detects invisible caries, impacted teeth and supernumerary teeth in children, while the 3D dental cone beam computed tomography (CBCT) is widely used in orthodontics and endodontics due to its low radiation dose. However, there is no open-access 2D public dataset for children's teeth and no open 3D dental CBCT dataset, which limits the development of automatic algorithms for segmenting teeth and analyzing diseases. The Semi-supervised Teeth Segmentation (STS) Challenge, a pioneering event in tooth segmentation, was held as a part of the MICCAI 2023 ToothFairy Workshop on the Alibaba Tianchi platform. This challenge aims to investigate effective semi-supervised tooth segmentation algorithms to advance the field of dentistry. In this challenge, we provide two modalities including the 2D panoramic X-ray images and the 3D CBCT tooth volumes. In Task 1, the goal was to segment tooth regions in panoramic X-ray images of both adult and pediatric teeth. Task 2 involved segmenting tooth sections using CBCT volumes. Limited labelled images with mostly unlabelled ones were provided in this challenge prompt using semi-supervised algorithms for training. In the preliminary round, the challenge received registration and result submission by 434 teams, with 64 advancing to the final round. This paper summarizes the diverse methods employed by the top-ranking teams in the STS MICCAI 2023 Challenge.

cs.CV↗

arXiv2024

nnSAM: Plug-and-play Segment Anything Model Improves nnUNet Performance

Automatic segmentation of medical images is crucial in modern clinical workflows. The Segment Anything Model (SAM) has emerged as a versatile tool for image segmentation without specific domain training, but it requires human prompts and may have limitations in specific domains. Traditional models like nnUNet perform automatic segmentation during inference and are effective in specific domains but need extensive domain-specific training. To combine the strengths of foundational and domain-specific models, we propose nnSAM, integrating SAM's robust feature extraction with nnUNet's automatic configuration to enhance segmentation accuracy on small datasets. Our nnSAM model optimizes two main approaches: leveraging SAM's feature extraction and nnUNet's domain-specific adaptation, and incorporating a boundary shape supervision loss function based on level set functions and curvature calculations to learn anatomical shape priors from limited data. We evaluated nnSAM on four segmentation tasks: brain white matter, liver, lung, and heart segmentation. Our method outperformed others, achieving the highest DICE score of 82.77% and the lowest ASD of 1.14 mm in brain white matter segmentation with 20 training samples, compared to nnUNet's DICE score of 79.25% and ASD of 1.36 mm. A sample size study highlighted nnSAM's advantage with fewer training samples. Our results demonstrate significant improvements in segmentation performance with nnSAM, showcasing its potential for small-sample learning in medical image segmentation.

cs.CV↗