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Yuxiang Zhao

Publications and source records attributed to Yuxiang Zhao.

At least 19 recordsLinked to original sources

Distinct Radiobiological Responses to BNCT in SAS Oral Squamous Cell Carcinoma and MCF-7 Breast Cancer Cells

This work compared the radiobiological responses of SAS oral squamous cell carcinoma cells and MCF-7 breast cancer cells following accelerator-based boron neutron capture therapy (BNCT). Neutrons were generated by bombarding a lithium target with proton beams, followed by moderation to obtain sufficient thermal neutrons for BNCT irradiation. Boronophenylalanine (BPA) was used as the boron delivery agent. BNCT-induced biological responses were evaluated by gamma-H2AX immunofluorescence staining, cell-cycle analysis, apoptosis analysis, and clonogenic survival assays. BNCT induced marked gamma-H2AX foci formation in both cell lines, indicating DNA damage-associated responses after irradiation. The two cell lines further showed distinct post-irradiation outcomes. SAS cells exhibited stronger clonogenic suppression and prominent G2/M accumulation, whereas MCF-7 cells showed sustained G0/G1 accumulation and delayed apoptosis. These results suggest that BNCT sensitivity is determined by both boron accumulation and cell-line-specific biological characteristics. This work provides experimental evidence highlighting the importance of tumor-dependent cellular responses in understanding and optimizing BNCT efficacy.

physics.med-ph

X-VC: Zero-shot Streaming Voice Conversion in Codec Space

Zero-shot voice conversion (VC) aims to convert a source utterance into the voice of an unseen target speaker while preserving its linguistic content. Although recent systems have improved conversion quality, building zero-shot VC systems for interactive scenarios remains challenging because high-fidelity speaker transfer and low-latency streaming inference are difficult to achieve simultaneously. In this work, we present X-VC, a zero-shot streaming VC system that performs one-step conversion in the latent space of a pretrained neural codec. X-VC uses a dual-conditioning acoustic converter that jointly models source codec latents and frame-level acoustic conditions derived from target reference speech, while injecting utterance-level target speaker information through adaptive normalization. To reduce the mismatch between training and inference, we train the model with generated paired data and a role-assignment strategy that combines standard, reconstruction, and reversed modes. For streaming inference, we further adopt a chunkwise inference scheme with overlap smoothing that is aligned with the segment-based training paradigm of the codec. Experiments on Seed-TTS-Eval show that X-VC achieves the best streaming WER in both English and Chinese, strong speaker similarity in same-language and cross-lingual settings, and substantially lower offline real-time factor than the compared baselines. These results suggest that codec-space one-step conversion is a practical approach for building high-quality low-latency zero-shot VC systems. Our audio samples, code and checkpoints are released at https://github.com/Jerrister/X-VC.

eess.AS

Low-energy Muon-Nucleon scattering experiment: LUNE (White Paper)

The HIAF will provide high-intensity, high-quality muon beams with momenta from 0.5 to 7.5 GeV/c. This energy range is uniquely suited for precision muon scattering, bridging the gap between low-energy electron facilities and future high-energy lepton-ion colliders. In particular, HIAF will enable precision measurements with both positive and negative muon beams over a broad kinematic range, complementing existing electron-scattering facilities such as JLab, EicC and EIC. Based on HIAF muon source, the LUNE Collaboration has been established to address several fundamental questions in nuclear and particle physics, including the proton charge radius puzzle, nucleon electromagnetic structure, and the dynamics of quantum electrodynamics and hadronic interactions. The program proceeds in two phases, from elastic scattering to nucleon structure and beyond-Standard-Model searches. The experiment is expected to determine the proton charge radius with a precision of approximately 1.0\% using elastic muon-proton scattering. It will also perform systematic measurements of the proton electromagnetic form factors with both $μ^+$ and $μ^-$ beams, enabling precise studies of two-photon exchange effects and stringent tests of quantum electrodynamics. Beyond elastic scattering, LUNE will investigate TMD, gravitational form factors, and nuclear charge radii, providing new insights into the 3D structure of nucleons and nuclei. The experiment will further address important topics including Coulomb-distortion corrections, nuclear medium effects, and possible signatures of physics beyond the Standard Model. This white paper presents the scientific motivation, detector concept, expected performance, and long-term strategy of LUNE.

hep-ex

Physics of the Electron-Ion Collider in China

The Electron-Ion Collider in China (EicC), a cutting-edge facility under development, aims to unveil the internal structure of nucleons and nuclei by leveraging collisions of high-intensity polarized electrons and ions (polarized protons, polarized deuterons, polarized $^{3}$He, and unpolarized heavy ions up to Uranium) at center-of-mass energies of 15-20 GeV and luminosity of (2-4)$\times 10^{33}$cm$^{-2}$s$^{-1}$. Its primary physics objectives include 3D tomography of nucleon spin and momentum structure, fundamental questions regarding the origin of nucleon mass, partonic structure of nuclei and parton interactions with the nuclear environment, and exploration of exotic hadronic states. In this paper, we review the physics potential of the EicC and highlight its unique capabilities for advancing precision nucleon structure studies by combining its specialized kinematic coverage and high luminosity. Since traditional topics like 3D nucleon structure have already been well-covered by several extensive reviews, we have deliberately dedicated significant space to recent progress in nucleon mass decomposition, nucleon energy-energy correlation, quantum information, and artificial intelligence applications in high-energy nuclear physics, which have been emerging rapidly and attracted a tremendous amount of attention in the community.

hep-ph

Saturation-Aware Predictive Quantization for Low-Power ECG Acquisition: A Benchmark of Taylor, Adaptive-Order, Kalman, and LSTM Predictors

Wearable electrocardiogram (ECG) monitors require energy-efficient analog-to-digital converters (ADCs), yet conventional successive-approximation-register (SAR) ADCs repeatedly resolve slowly varying most significant bits. Predictive quantization (PQ) instead estimates the next sample and quantizes only the residual, thereby reducing the required conversion depth. Its principal failure mode is residual saturation, which occurs when prediction error exceeds the residual ADC range and is irreversibly clipped. We compared four one-step-ahead predictors under a common 10-bit, saturation-aware PQ model with residual widths from 2 to 8 bits. The benchmark included first-order Taylor extrapolation, an adaptive-order predictor, a constant-velocity Kalman filter, and a two-layer long short-term memory (LSTM) network. We used an open-loop protocol in which all predictors received past original samples. This protocol isolates intrinsic prediction performance from recursive reconstruction-error propagation. Saturation rate (SR) was the primary metric, complemented by overflow energy ratio (OER), which weights each event by its squared overflow depth. On a 5,317-sample excerpt from MIT-BIH Arrhythmia Database Record 101, the Kalman predictor performed best at Br=6. It achieved 30.88 dB SNR, 2.16% SR, and 12.93% OER, compared with 28.39 dB, 2.69%, and 25.29% for Taylor extrapolation. The adaptive-order predictor achieved 29.61 dB SNR and 2.44% SR using three registers, two comparators, and no multiplier. The LSTM reached 29.28 dB SNR and did not outperform the model-based predictors on this limited-data benchmark. Under the evaluated excerpt and open-loop protocol, Br=6 provided a favorable balance between reconstruction fidelity and conversion depth. Closed-loop, multi-subject, and hardware validation are required before system-level energy or deployment claims can be made.

eess.SP

GoGoTB: Agentic RTL Verification with Specification-Grounded Coverage Closure

Functional verification dominates integrated circuit (IC) front-end engineering effort, and a single missed bug that escapes to silicon can trigger a costly respin. Recent large language models (LLMs) offer new opportunities to automate this process, yet existing LLM-based approaches generate each component through independent single-turn calls with no shared context, leaving interface mismatches undetected and reported coverage disconnected from specification requirements. To address these challenges, we present GoGoTB, an agentic framework that achieves end-to-end verification closure through three subsystems: an agentic execution control layer, an evolvable knowledge system, and specification-grounded coverage closure. The execution control layer separates deterministic enforcement from LLM reasoning at every tool and stage boundary. The knowledge system dispatches methodology and design-specific expertise on demand. The coverage framework anchors every bin to a named specification behavior so that each residual gap has a diagnosable root cause and a targeted remedy. Tested on 8 register transfer level (RTL) designs without any human intervention, GoGoTB achieves 100\% environment generation success and averages 98.4\% line, 97.2\% branch, 97.0\% toggle, and 83.2\% functional coverage. No prior work successfully generates a complete verification environment or achieves meaningful coverage on the same benchmarks.

cs.AI

X-Translator: A Real-Time Multilingual Speaker-Aware Speech-to-Speech Translation System

Real-time speech-to-speech translation (S2ST) systems must balance translation quality, latency, speech naturalness, and speaker consistency. Publicly documented S2ST systems have advanced direct, multilingual, streaming, and expressive modeling, while proprietary products and APIs increasingly expose real-time translation capabilities to users. However, practical deployment remains challenging for open and reproducible systems, especially in long-form and multi-speaker conversations where partial ASR hypotheses are unstable, turn boundaries are ambiguous, and target speech must be generated with an appropriate speaker prompt. We present X-Translator, a low-cost modular cascaded S2ST system that combines streaming ASR, machine translation, and prompt-conditioned TTS through a session-level runtime controller. The system uses incremental segment commitment to convert unstable ASR streams into translation-ready units, and an online speaker prompt manager to bind source speech spans to speaker-specific voice prompts for synthesis. We evaluate translation, speech quality, and latency with OpenSTBench, compare against proprietary speech translation APIs as behavioral baselines, measure long-form voice stability, evaluate speaker preservation in multi-speaker conversations, and assess multilingual translation quality. X-Translator provides an open platform for understanding the practical trade-offs of deployment-oriented S2ST. Code and demo are available at https://github.com/zhaoyx239/X-Translator.

eess.AS

A Kalman Filter-Assisted Data-Predictive SAR ADC With Reduced Switching Energy for Low-Power Applications

The proliferation of Internet of Things (IoT) devices and wearable health monitors has created an urgent demand for ultra-low-power analog-to-digital converters (ADCs). Successive approximation register (SAR) ADCs are widely used in such applications, yet their energy efficiency remains constrained by the sequential bit-by-bit switching of the capacitive DAC (CDAC). The high-weight most significant bit (MSB) transitions dominate the total switching energy, and the rigid N -cycle conversion flow imposes a hard lower bound on latency per sample.This paper presents a Kalman filter-assisted data-predictive SAR ADC that replaces the first four comparator-driven decisions with a recursive state estimator. The Kalman filter predicts the 4 MSBs from the complete conversion history before each cycle begins, enabling simultaneous parallel switching of the MSB capacitors. This eliminates redundant CDAC transitions, shortens the quantization cycle by four clock periods, and reduces switching energy by approximately 50%. An optimized 4-bit MSB switching scheme further suppresses residual switching at the hardware level. The ADC, designed in a 180-nm CMOS process, supports configurable dual-mode operation, toggling between a conventional mode and the Kalman-driven predictive mode for robustness under erratic inputs. At 20 MS/s and a 1.8-V supply, the predictive mode reduces total power consumption by 50.3% (from 1.96 mW to 0.975 mW), with a measured SNR/SFDR of 57.88/74.51 dB at 504 kHz, confirming its suitability for energy-constrained wireless sensor networks.

eess.SP

Analysis of Nuclear Fragmentation Functions for Pions with $A$ and $ν$ Dependence

We present a QCD analysis of pion nuclear fragmentation functions (nFFs), which encode nuclear modifications to hadronization in high-energy nuclear collisions. Within this framework, vacuum fragmentation functions and their nuclear modifications are extracted simultaneously. The nuclear effects are parameterized as functions of the mass number $A$, the energy of the fragmenting parton in the target rest frame $ν$, and the hadron energy fraction $z$, allowing their dependence on these variables to be quantified. Our analysis includes semi-inclusive deep-inelastic scattering data on nuclear targets, with kinematic cuts chosen to ensure the applicability of perturbative QCD and collinear factorization. The resulting fit provides a good description of most datasets, with the nFFs well constrained in the energy fraction range $z \in [0.2, 0.7]$. Additionally, with our new nFFs, we present next-to-leading order predictions in $pp$ and $pA$ collisions, which show reasonable agreement with ALICE data within the current experimental uncertainties.

hep-ph

Miniaturized Photoacoustic Spectroscopy Gas Probe for In-Situ Detection in Oil

This paper designs and develops a miniaturized photoacoustic spectroscopy gas probe with acoustic pressure enhancement for in-situ detection in oil-immersed power equipment. The probe adopts a single-cavity single-fiber structure, integrating the photoacoustic cell and the Fabry-Pérot optical sensing cavity within a ceramic ferrule with an outer diameter of only 800 um. Through the electro-mechanical-acoustic equivalent model analysis of the semi-open photoacoustic cell, the enhancement mechanism is revealed that reducing the radius of the photoacoustic cell can form a flat region in the acoustic pressure response. The CrAgAu composite metal diaphragm is fabricated by electron-beam evaporation, and the gas vents are precisely machined by focused-ion-beam etching, successfully realizing the preparation of the sensor prototype. Experimental results demonstrate that the sensor exhibits a flat acoustic response in the frequency range of 2800-10000 Hz with a sensitivity of -15 dB re 1 mV/Pa. Using acetylene as the target gas, the detection limit reaches 71.4 ppb (with an integration time of 130 s) at the optimal operating frequency of 3275 Hz, and the linearity exceeds 0.998. In-oil tests verify its stable detection capability in oil-phase environments, providing a miniaturized, high-sensitivity all-optical technical solution for in-situ monitoring of dissolved gases in transformer oil.

physics.ins-det

OpenSTBench: Beyond Semantic Evaluation for Speech Translation

Speech translation systems increasingly span speech-to-text translation (S2TT), speech-to-speech translation (S2ST), offline translation, and streaming generation, producing outputs that differ in modality, speech realization, and timing behavior. Existing evaluation practices assess important aspects such as translation quality, speech quality, and temporal quality, but these aspects are often evaluated under separate protocols, making it difficult to compare heterogeneous systems comprehensively. To address this gap, we present OpenSTBench, a unified multidimensional evaluation framework that organizes heterogeneous speech translation outputs into a shared evaluation format. OpenSTBench supports both S2TT and S2ST systems in offline and streaming settings, and jointly evaluates translation quality, speech quality, speaker preservation, emotion and paralinguistic fidelity, temporal consistency, and latency. Through experiments on representative speech translation systems, we show that systems with strong translation quality can still differ substantially in speech quality, as well as in temporal quality. OpenSTBench provides a reproducible protocol for analyzing these cross-dimensional differences and supporting application-oriented comparison of speech translation systems. The code and datasets are available at https://github.com/sjtuayj/OpenSTBench.

eess.AS

POINav: Benchmarking and Enhancing Final-Meters Arrival in Real-World Vision-Language Navigation

Real-world navigation is fundamentally driven by Points of Interest (POIs), yet reaching a precise POI remains a critical "final-meters" challenge. Existing Vision-Language Navigation (VLN) benchmarks of POI-goal navigation often suffer from coarse granularity or significant sim-to-real gaps due to generated scene. To bridge this gap, we present POINav-Bench, the first benchmark designed for closed-loop evaluation of real-world POI-goal navigation. It comprises 11 commercial areas reconstructed from real-world captures using 3D Gaussian Splatting (3DGS), covering 126,398 $m^{2}$ in total and spanning 163 distinct POIs. With traversability-aware annotations and reference trajectories, POINav-Bench enables high-fidelity evaluation of navigation agents in realistic, POI-rich real-world environments. Building on this, we propose the POINav Brain-Action Framework where a Brain module performs POI-grounded reasoning to guide an Action module in predicting continuous waypoints for real-world execution. We further curate the POINav-Dataset, containing 70K real-world signage-entrance pairs. Experiments show that our framework provides a viable path toward refining real-world POI-goal navigation.

cs.RO

Conceptual Design of PID Detectors for the EicC Spectrometer

The Electron-ion collider in China (EicC) is a proposed future electron-ion collider designed to achieve a high luminosity, with a center-of-mass energy ranging from 15 to 20 GeV. Excellent particle identification (PID) with extensive momentum coverage is essential for investigating exclusive and semi-inclusive processes, as well as enabling precise 3D imaging of the nucleon structure in the EicC experiment. To meet its PID requirement, the EicC Collaboration has proposed the conceptual design of various Cherenkov detectors, including the DIRC in the barrel region and the RICH in the endcap region. It also involving the TOF detector for PID in the low momentum region. The GEANT4 simulation, which integrate advanced optical transmission models and image reconstruction algorithms, have been conducted to study and optimize the performance of these detectors.

physics.ins-det

Chatting about Upper-Body Expressive Human Pose and Shape Estimation

Expressive Human Pose and Shape Estimation (EHPS) plays a crucial role in various AR/VR applications and has witnessed significant progress in recent years. However, current state-of-the-art methods still struggle with accurate parameter estimation for facial and hand regions and exhibit limited generalization to wild images. To address these challenges, we present CoEvoer, a novel one-stage synergistic cross-dependency transformer framework tailored for upper-body EHPS. CoEvoer enables explicit feature-level interaction across different body parts, allowing for mutual enhancement through contextual information exchange. Specifically, larger and more easily estimated regions such as the torso provide global semantics and positional priors to guide the estimation of finer, more complex regions like the face and hands. Conversely, the localized details captured in facial and hand regions help refine and calibrate adjacent body parts. To the best of our knowledge, CoEvoer is the first framework designed specifically for upper-body EHPS, with the goal of capturing the strong coupling and semantic dependencies among the face, hands, and torso through joint parameter regression. Extensive experiments demonstrate that CoEvoer achieves state-of-the-art performance on upper-body benchmarks and exhibits strong generalization capability even on unseen wild images.

cs.CV

Chatting about Conditional Trajectory Prediction

Human behavior has the nature of mutual dependencies, which requires human-robot interactive systems to predict surrounding agents trajectories by modeling complex social interactions, avoiding collisions and executing safe path planning. While there exist many trajectory prediction methods, most of them do not incorporate the own motion of the ego agent and only model interactions based on static information. We are inspired by the humans theory of mind during trajectory selection and propose a Cross time domain intention-interactive method for conditional Trajectory prediction(CiT). Our proposed CiT conducts joint analysis of behavior intentions over time, and achieves information complementarity and integration across different time domains. The intention in its own time domain can be corrected by the social interaction information from the other time domain to obtain a more precise intention representation. In addition, CiT is designed to closely integrate with robotic motion planning and control modules, capable of generating a set of optional trajectory prediction results for all surrounding agents based on potential motions of the ego agent. Extensive experiments demonstrate that the proposed CiT significantly outperforms the existing methods, achieving state-of-the-art performance in the benchmarks.

cs.RO

Anonymization, Not Elimination: Utility-Preserved Speech Anonymization

The growing reliance on large-scale speech data has made privacy protection a critical concern. However, existing anonymization approaches often degrade data utility, for example by disrupting acoustic continuity or reducing vocal diversity, which compromises the value of speech data for downstream tasks such as Automatic Speech Recognition (ASR), Text-to-Speech (TTS), and Speech Emotion Recognition (SER). Current evaluation practices are also limited, as they mainly rely on direct testing of anonymized speech with pretrained models, providing only a partial view of utility. To address these issues, we propose a novel two-stage framework that protects both linguistic content and acoustic identity while maintaining usability. For content privacy, we employ a generative speech editing model to seamlessly replace personally identifiable information (PII), and for voice privacy, we introduce F3-VA, a flow-matching-based anonymization framework with a three-stage design that produces diverse and distinct anonymized speakers. To enable a more comprehensive assessment, we evaluate privacy using both acoustic- and content-based speaker verification metrics, and assess utility by training ASR, TTS, and SER models from scratch. Experimental results show that our framework achieves stronger privacy protection with minimal utility degradation compared to baselines from the VoicePrivacy Challenge, while the proposed evaluation protocol provides a more realistic reflection of the utility of anonymized speech under privacy protection.

eess.AS

Design and Performance Simulation of the Electromagnetic Calorimeter at EicC

The electromagnetic calorimeter (ECAL) is a key detector component for precise electron and photon measurements in electron-ion collision experiments. At the Electron-Ion Collider in China (EicC), high-performance calorimetry is essential for exploring the internal structure of nucleons and studying the dynamics of quarks and gluons within quantum chromodynamics (QCD). This paper presents the optimized design and performance simulation of the EicC ECAL system. The ECAL consists of three specialized sections tailored to distinct detection environments: (1) an electron-Endcap employing high-resolution pure Cesium Iodide (pCsI) crystals, (2) a central barrel, and (3) an ion-Endcap, both adopting a cost-effective Shashlik-style sampling calorimeter with improved light yield. Each segment's geometry and material composition have been systematically optimized through Geant4 simulations to achieve excellent energy and position resolutions as well as strong electron-pion discrimination. The simulated performance indicates that the ECAL can achieve energy resolutions of 2 percent divided by sqrt(E) for pCsI crystals and 5 percent divided by sqrt(E) for Shashlik modules, meeting the design goals of the EicC detector.

physics.ins-det

SoulX-Duplug: Plug-and-Play Streaming State Prediction Module for Realtime Full-Duplex Speech Conversation

Recent advances in spoken dialogue systems have brought increased attention to human-like full-duplex voice interactions. However, our comprehensive review of this field reveals several challenges, including the difficulty in obtaining training data, catastrophic forgetting, and limited scalability. In this work, we propose SoulX-Duplug, a plug-and-play streaming state prediction module for full-duplex spoken dialogue systems. By jointly performing streaming ASR, SoulX-Duplug explicitly leverages textual information to identify user intent, effectively serving as a semantic VAD. To promote fair evaluation, we introduce SoulX-Duplug-Eval, extending widely used benchmarks with improved bilingual coverage. Experimental results show that SoulX-Duplug enables low-latency streaming dialogue state control, and the system built upon it outperforms existing full-duplex models in overall turn management and latency performance. We have open-sourced SoulX-Duplug and SoulX-Duplug-Eval.

eess.AS