arXiv subjects

Zhen Tian

Publications and source records attributed to Zhen Tian.

At least 55 records · Page 3Linked to original sources

arXiv2025

Frequency-Domain Denoising-Based in Vivo Fluorescence Imaging

The second near-infrared window (NIR-II, 900-1,880 nm) has been pivotal in advancing in vivo fluorescence imaging due to its superior penetration depth and contrast. Yet, its clinical utility remains limited by insufficient imaging temporal-spatial resolution and the absence of U.S. Food and Drug Administration (FDA)-approved NIR-II contrast agents. This work presents a frequency-domain denoising (FDD)-based in vivo fluorescence imaging technique, which can improve signal-to-background ratio (SBR) and signal-to-noise ratio (SNR) by more than 2,500-fold and 300-fold, respectively. The great enhancement yields a doubled penetration depth and a 95% reduction in contrast agent dosage or excitation light intensity for mouse vascular imaging. Additionally, we achieved a SBR far exceeded the Rose criterion in the observation of tumor margins and vessels in mice using Indocyanine Green (ICG), demonstrating the feasibility of NIR-II surgical navigation with FDA-approved agents. Furthermore, a 600 Hz real-time video enables visualization of the entire contrast agent diffusion process within the mouse body and differentiation between arteries and veins. This innovative technique, characterized by exceptional sensitivity, efficiency, and robustness, presents a promising solution for clinical applications, particularly in NIR-II surgical navigation.

physics.bio-ph↗

arXiv2025

YOLO-FireAD: Efficient Fire Detection via Attention-Guided Inverted Residual Learning and Dual-Pooling Feature Preservation

Fire detection in dynamic environments faces continuous challenges, including the interference of illumination changes, many false detections or missed detections, and it is difficult to achieve both efficiency and accuracy. To address the problem of feature extraction limitation and information loss in the existing YOLO-based models, this study propose You Only Look Once for Fire Detection with Attention-guided Inverted Residual and Dual-pooling Downscale Fusion (YOLO-FireAD) with two core innovations: (1) Attention-guided Inverted Residual Block (AIR) integrates hybrid channel-spatial attention with inverted residuals to adaptively enhance fire features and suppress environmental noise; (2) Dual Pool Downscale Fusion Block (DPDF) preserves multi-scale fire patterns through learnable fusion of max-average pooling outputs, mitigating small-fire detection failures. Extensive evaluation on two public datasets shows the efficient performance of our model. Our proposed model keeps the sum amount of parameters (1.45M, 51.8% lower than YOLOv8n) (4.6G, 43.2% lower than YOLOv8n), and mAP75 is higher than the mainstream real-time object detection models YOLOv8n, YOL-Ov9t, YOLOv10n, YOLO11n, YOLOv12n and other YOLOv8 variants 1.3-5.5%. For more details, please visit our repository: https://github.com/JEFfersusu/YOLO-FireAD

cs.CV↗

arXiv2025

Semi-Supervised Defect Detection via Conditional Diffusion and CLIP-Guided Noise Filtering

In the realm of industrial quality inspection, defect detection stands as a critical component, particularly in high-precision, safety-critical sectors such as automotive components aerospace, and medical devices. Traditional methods, reliant on manual inspection or early image processing algorithms, suffer from inefficiencies, high costs, and limited robustness. This paper introduces a semi-supervised defect detection framework based on conditional diffusion (DSYM), leveraging a two-stage collaborative training mechanism and a staged joint optimization strategy. The framework utilizes labeled data for initial training and subsequently incorporates unlabeled data through the generation of pseudo-labels. A conditional diffusion model synthesizes multi-scale pseudo-defect samples, while a CLIP cross-modal feature-based noise filtering mechanism mitigates label contamination. Experimental results on the NEU-DET dataset demonstrate a 78.4% mAP@0.5 with the same amount of labeled data as traditional supervised methods, and 75.1% mAP@0.5 with only 40% of the labeled data required by the original supervised model, showcasing significant advantages in data efficiency. This research provides a high-precision, low-labeling-dependent solution for defect detection in industrial quality inspection scenarios. The work of this article has been open-sourced at https://github.com/cLin-c/Semisupervised-DSYM.

cs.CV↗

arXiv2025

Limited-Angle CBCT Reconstruction via Geometry-Integrated Cycle-domain Denoising Diffusion Probabilistic Models

Cone-beam CT (CBCT) is widely used in clinical radiotherapy for image-guided treatment, improving setup accuracy, adaptive planning, and motion management. However, slow gantry rotation limits performance by introducing motion artifacts, blurring, and increased dose. This work aims to develop a clinically feasible method for reconstructing high-quality CBCT volumes from consecutive limited-angle acquisitions, addressing imaging challenges in time- or dose-constrained settings. We propose a limited-angle (LA) geometry-integrated cycle-domain (LA-GICD) framework for CBCT reconstruction, comprising two denoising diffusion probabilistic models (DDPMs) connected via analytic cone-beam forward and back projectors. A Projection-DDPM completes missing projections, followed by back-projection, and an Image-DDPM refines the volume. This dual-domain design leverages complementary priors from projection and image spaces to achieve high-quality reconstructions from limited-angle (<= 90 degrees) scans. Performance was evaluated against full-angle reconstruction. Four board-certified medical physicists conducted assessments. A total of 78 planning CTs in common CBCT geometries were used for training and evaluation. The method achieved a mean absolute error of 35.5 HU, SSIM of 0.84, and PSNR of 29.8 dB, with visibly reduced artifacts and improved soft-tissue clarity. LA-GICD's geometry-aware dual-domain learning, embedded in analytic forward/backward operators, enabled artifact-free, high-contrast reconstructions from a single 90-degree scan, reducing acquisition time and dose four-fold. LA-GICD improves limited-angle CBCT reconstruction with strong data fidelity and anatomical realism. It offers a practical solution for short-arc acquisitions, enhancing CBCT use in radiotherapy by providing clinically applicable images with reduced scan time and dose for more accurate, personalized treatments.

cs.CV↗

arXiv2025

Automated Treatment Planning for Interstitial HDR Brachytherapy for Locally Advanced Cervical Cancer using Deep Reinforcement Learning

High-dose-rate (HDR) brachytherapy plays a critical role in the treatment of locally advanced cervical cancer but remains highly dependent on manual treatment planning expertise. The objective of this study is to develop a fully automated HDR brachytherapy planning framework that integrates reinforcement learning (RL) and dose-based optimization to generate clinically acceptable treatment plans with improved consistency and efficiency. We propose a hierarchical two-stage autoplanning framework. In the first stage, a deep Q-network (DQN)-based RL agent iteratively selects treatment planning parameters (TPPs), which control the trade-offs between target coverage and organ-at-risk (OAR) sparing. The agent's state representation includes both dose-volume histogram (DVH) metrics and current TPP values, while its reward function incorporates clinical dose objectives and safety constraints, including D90, V150, V200 for targets, and D2cc for all relevant OARs (bladder, rectum, sigmoid, small bowel, and large bowel). In the second stage, a customized Adam-based optimizer computes the corresponding dwell time distribution for the selected TPPs using a clinically informed loss function. The framework was evaluated on a cohort of patients with complex applicator geometries. The proposed framework successfully learned clinically meaningful TPP adjustments across diverse patient anatomies. For the unseen test patients, the RL-based automated planning method achieved an average score of 93.89%, outperforming the clinical plans which averaged 91.86%. These findings are notable given that score improvements were achieved while maintaining full target coverage and reducing CTV hot spots in most cases.

physics.med-ph↗

arXiv2025

A Large Convolutional Neural Network for Clinical Target and Multi-organ Segmentation in Gynecologic Brachytherapy with Multi-stage Learning

Purpose: Accurate segmentation of clinical target volumes (CTV) and organs-at-risk is crucial for optimizing gynecologic brachytherapy (GYN-BT) treatment planning. However, anatomical variability, low soft-tissue contrast in CT imaging, and limited annotated datasets pose significant challenges. This study presents GynBTNet, a novel multi-stage learning framework designed to enhance segmentation performance through self-supervised pretraining and hierarchical fine-tuning strategies. Methods: GynBTNet employs a three-stage training strategy: (1) self-supervised pretraining on large-scale CT datasets using sparse submanifold convolution to capture robust anatomical representations, (2) supervised fine-tuning on a comprehensive multi-organ segmentation dataset to refine feature extraction, and (3) task-specific fine-tuning on a dedicated GYN-BT dataset to optimize segmentation performance for clinical applications. The model was evaluated against state-of-the-art methods using the Dice Similarity Coefficient (DSC), 95th percentile Hausdorff Distance (HD95), and Average Surface Distance (ASD). Results: Our GynBTNet achieved superior segmentation performance, significantly outperforming nnU-Net and Swin-UNETR. Notably, it yielded a DSC of 0.837 +/- 0.068 for CTV, 0.940 +/- 0.052 for the bladder, 0.842 +/- 0.070 for the rectum, and 0.871 +/- 0.047 for the uterus, with reduced HD95 and ASD compared to baseline models. Self-supervised pretraining led to consistent performance improvements, particularly for structures with complex boundaries. However, segmentation of the sigmoid colon remained challenging, likely due to anatomical ambiguities and inter-patient variability. Statistical significance analysis confirmed that GynBTNet's improvements were significant compared to baseline models.

cs.CV↗

arXiv2025

Applications and Effect Evaluation of Generative Adversarial Networks in Semi-Supervised Learning

In recent years, image classification, as a core task in computer vision, relies on high-quality labelled data, which restricts the wide application of deep learning models in practical scenarios. To alleviate the problem of insufficient labelled samples, semi-supervised learning has gradually become a research hotspot. In this paper, we construct a semi-supervised image classification model based on Generative Adversarial Networks (GANs), and through the introduction of the collaborative training mechanism of generators, discriminators and classifiers, we achieve the effective use of limited labelled data and a large amount of unlabelled data, improve the quality of image generation and classification accuracy, and provide an effective solution for the task of image recognition in complex environments.

cs.CV↗

arXiv2025

Machine Learning Algorithm for Noise Reduction and Disease-Causing Gene Feature Extraction in Gene Sequencing Data

In this study, we propose a machine learning-based method for noise reduction and disease-causing gene feature extraction in gene sequencing DeepSeqDenoise algorithm combines CNN and RNN to effectively remove the sequencing noise, and improves the signal-to-noise ratio by 9.4 dB. We screened 17 key features by feature engineering, and constructed an integrated learning model to predict disease-causing genes with 94.3% accuracy. We successfully identified 57 new candidate disease-causing genes in a cardiovascular disease cohort validation, and detected 3 missed variants in clinical applications. The method significantly outperforms existing tools and provides strong support for accurate diagnosis of genetic diseases.

cs.LG↗

arXiv2025

Stereotactic Arrhythmia Radioablation for Refractory Ventricular Tachycardia: A Narrative Review and Exploratory Pooled Analysis of Clinical Outcomes and Toxicity

Purpose: Stereotactic arrhythmia radioablation (STAR) is a non-invasive salvage therapy for refractory ventricular tachycardia (VT), especially in patients ineligible for catheter ablation. This narrative review and pooled analysis evaluates the safety, efficacy, and technical characteristics of STAR, integrating preclinical studies, case reports, case series, and clinical trials. Methods and Materials: A comprehensive review identified 86 studies published between 2015 and 2025, including 12 preclinical studies, 49 case reports, 18 case series, and 7 clinical trials. Study-level data were extracted for pooled analysis of 6- and 12-month mortality, VT burden reduction, and grade 3+ acute toxicities. Subgroup analyses were performed by delivery modality, age, left ventricular ejection fraction (LVEF), and cardiomyopathy type. Results: Pooled mortality was 16% (95% CI: 11-20%) at 6 months and 33% (95% CI: 27-38%) at 12 months. VT burden reduction at 6 months averaged 75% (95% CI: 73-77%) but showed substantial heterogeneity (I^2 = 98.8%). Grade 3+ acute toxicities occurred in 7% (95% CI: 4-10%), with heart failure being most common. Subgroup analyses suggested better outcomes in younger patients, those with NICM, and those with higher LVEF. Conclusions: STAR is a promising salvage therapy with favorable acute safety and efficacy. Outcome heterogeneity and inconsistent reporting highlight the need for standardized definitions, dosimetric protocols, and longer-term follow-up. Prospective trials and real-world registries are critical for refining STAR's role in VT management.

physics.med-ph↗

arXiv2025

An ACO-MPC Framework for Energy-Efficient and Collision-Free Path Planning in Autonomous Maritime Navigation

Automated driving on ramps presents significant challenges due to the need to balance both safety and efficiency during lane changes. This paper proposes an integrated planner for automated vehicles (AVs) on ramps, utilizing an unsatisfactory level metric for efficiency and arrow-cluster-based sampling for safety. The planner identifies optimal times for the AV to change lanes, taking into account the vehicle's velocity as a key factor in efficiency. Additionally, the integrated planner employs arrow-cluster-based sampling to evaluate collision risks and select an optimal lane-changing curve. Extensive simulations were conducted in a ramp scenario to verify the planner's efficient and safe performance. The results demonstrate that the proposed planner can effectively select an appropriate lane-changing time point and a safe lane-changing curve for AVs, without incurring any collisions during the maneuver.

eess.SY↗

arXiv2025

Adaptive Field Effect Planner for Safe Interactive Autonomous Driving on Curved Roads

Autonomous driving has garnered significant attention for its potential to improve safety, traffic efficiency, and user convenience. However, the dynamic and complex nature of interactive driving poses significant challenges, including the need to navigate non-linear road geometries, handle dynamic obstacles, and meet stringent safety and comfort requirements. Traditional approaches, such as artificial potential fields (APF), often fall short in addressing these complexities independently, necessitating the development of integrated and adaptive frameworks. This paper presents a novel approach to autonomous vehicle navigation that integrates artificial potential fields, Frenet coordinates, and improved particle swarm optimization (IPSO). A dynamic risk field, adapted from traditional APF, is proposed to ensure interactive safety by quantifying risks and dynamically adjusting lane-changing intentions based on surrounding vehicle behavior. Frenet coordinates are utilized to simplify trajectory planning on non-straight roads, while an enhanced quintic polynomial trajectory generator ensures smooth and comfortable path transitions. Additionally, an IPSO algorithm optimizes trajectory selection in real time, balancing safety and user comfort within a feasible input range. The proposed framework is validated through extensive simulations and real-world scenarios, demonstrating its ability to navigate complex traffic environments, maintain safety margins, and generate smooth, dynamically feasible trajectories.

eess.SY↗

arXiv2025

Data-Driven Evolutionary Game-Based Model Predictive Control for Hybrid Renewable Energy Dispatch in Autonomous Ships

In this paper, we propose a data-driven Evolutionary Game-Based Model Predictive Control (EG-MPC) framework for the energy dispatch of a hybrid renewable energy system powering an autonomous ship. The system integrates solar photovoltaic and wind turbine generation with battery energy storage and diesel backup power to ensure reliable operation. Given the uncertainties in renewable generation and dynamic energy demands, an optimal dispatch strategy is crucial to minimize operational costs while maintaining system reliability. To address these challenges, we formulate a cost minimization problem that considers both battery degradation costs and diesel fuel expenses, leveraging real-world data to enhance modeling accuracy. The EG-MPC approach integrates evolutionary game dynamics within a receding-horizon optimization framework, enabling adaptive and near-optimal control solutions in real time. Simulation results based on site-specific data demonstrate that the proposed method achieves cost-effective, reliable, and adaptive energy dispatch, outperforming conventional rule-based and standard MPC approaches, particularly under uncertainty.

eess.SY↗

arXiv2025

Efficient and Safe Planner for Automated Driving on Ramps Considering Unsatisfication

cs.RO↗

arXiv2025

Intelligent road crack detection and analysis based on improved YOLOv8

As urbanization speeds up and traffic flow increases, the issue of pavement distress is becoming increasingly pronounced, posing a severe threat to road safety and service life. Traditional methods of pothole detection rely on manual inspection, which is not only inefficient but also costly. This paper proposes an intelligent road crack detection and analysis system, based on the enhanced YOLOv8 deep learning framework. A target segmentation model has been developed through the training of 4029 images, capable of efficiently and accurately recognizing and segmenting crack regions in roads. The model also analyzes the segmented regions to precisely calculate the maximum and minimum widths of cracks and their exact locations. Experimental results indicate that the incorporation of ECA and CBAM attention mechanisms substantially enhances the model's detection accuracy and efficiency, offering a novel solution for road maintenance and safety monitoring.

cs.CV↗

arXiv2025

Fundus2Globe: Generative AI-Driven 3D Digital Twins for Personalized Myopia Management

Myopia, projected to affect 50% population globally by 2050, is a leading cause of vision loss. Eyes with pathological myopia exhibit distinctive shape distributions, which are closely linked to the progression of vision-threatening complications. Recent understanding of eye-shape-based biomarkers requires magnetic resonance imaging (MRI), however, it is costly and unrealistic in routine ophthalmology clinics. We present Fundus2Globe, the first AI framework that synthesizes patient-specific 3D eye globes from ubiquitous 2D color fundus photographs (CFPs) and routine metadata (axial length, spherical equivalent), bypassing MRI dependency. By integrating a 3D morphable eye model (encoding biomechanical shape priors) with a latent diffusion model, our approach achieves submillimeter accuracy in reconstructing posterior ocular anatomy efficiently. Fundus2Globe uniquely quantifies how vision-threatening lesions (e.g., staphylomas) in CFPs correlate with MRI-validated 3D shape abnormalities, enabling clinicians to simulate posterior segment changes in response to refractive shifts. External validation demonstrates its robust generation performance, ensuring fairness across underrepresented groups. By transforming 2D fundus imaging into 3D digital replicas of ocular structures, Fundus2Globe is a gateway for precision ophthalmology, laying the foundation for AI-driven, personalized myopia management.

eess.IV↗

arXiv2025

A Comparative Dosimetric Study of Proton and Photon Therapy in Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia

Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-invasive option for such patients. While photon-based STAR has shown efficacy, proton therapy offers potential advantages due to its superior dose conformity and sparing of critical OARs, including the heart itself. This study aims to investigate and compare the dosimetry between proton and photon therapy for VT, focusing on target coverage and OAR sparing. Methods: We performed a retrospective study on a cohort of 34 VT patients who received photon STAR. Proton STAR plans were generated using robust optimization in RayStation to deliver the same prescription dose of 25 Gy in a single fraction while minimizing dose to OARs. Dosimetric metrics, including D99, D95, Dmean, and D0.03cc, were extracted for critical OARs and VAS. Shapiro-Wilk tests were used to assess normality, followed by paired t-tests or Wilcoxon signed-rank tests for statistical comparisons between modalities, with Bonferroni correction applied for multiple comparisons. Results: Proton and photon plans achieved comparable target coverage, with VAS D95 of 24.1 +/- 1.2 Gy vs. 24.7 +/- 1.0 Gy (p=0.294). Proton therapy significantly reduced OAR doses, including heart Dmean (3.6 +/- 1.5 Gy vs. 5.5 +/- 2.0 Gy, p<0.001), lungs Dmean (1.6 +/- 1.5 Gy vs. 2.1 +/- 1.4 Gy, p<0.001), and esophagus Dmean (0.3 +/- 0.6 Gy vs. 1.6 +/- 1.3 Gy, p<0.001), while maintaining optimal target coverage. Conclusion: Proton therapy for STAR demonstrates significant dosimetric advantages in sparing the heart and other critical OARs compared to photon therapy for VT, while maintaining equivalent target coverage. These findings highlight the potential of proton therapy to reduce treatment-related toxicity and improve outcomes for VT patients.

physics.med-ph↗

arXiv2025

Irrational Complex Rotations Empower Low-bit Optimizers

In this paper, we propose a novel optimizer state compression algorithm, namely $π$-Quant, which leverages the properties of irrational numbers (e.g., $π$) for memory-efficient training. The core idea is based on our mathematical findings, which show that a pair of parameters can be represented by a single rotation angle using the complex rotation scheme. Building on this insight, we map the parameters into a complex space and perform quantization using the corresponding rotation angles. To efficiently integrate it into optimization process, we develop an efficient system of geometric equations that computes the precise rotation angles with linear complexity. We evaluate $π$-Quant on a wide range of tasks. Our experiments show that it can reduce the bit-width of parameters to 3.32-bit, achieving a 75% reduction in parameter scale and a 40% decrease in GPU memory usage, all while maintaining full accuracy.

cs.LG↗

arXiv2025

Evaluating Scenario-based Decision-making for Interactive Autonomous Driving Using Rational Criteria: A Survey

Autonomous vehicles (AVs) can significantly promote the advances in road transport mobility in terms of safety, reliability, and decarbonization. However, ensuring safety and efficiency in interactive during within dynamic and diverse environments is still a primary barrier to large-scale AV adoption. In recent years, deep reinforcement learning (DRL) has emerged as an advanced AI-based approach, enabling AVs to learn decision-making strategies adaptively from data and interactions. DRL strategies are better suited than traditional rule-based methods for handling complex, dynamic, and unpredictable driving environments due to their adaptivity. However, varying driving scenarios present distinct challenges, such as avoiding obstacles on highways and reaching specific exits at intersections, requiring different scenario-specific decision-making algorithms. Many DRL algorithms have been proposed in interactive decision-making. However, a rationale review of these DRL algorithms across various scenarios is lacking. Therefore, a comprehensive evaluation is essential to assess these algorithms from multiple perspectives, including those of vehicle users and vehicle manufacturers. This survey reviews the application of DRL algorithms in autonomous driving across typical scenarios, summarizing road features and recent advancements. The scenarios include highways, on-ramp merging, roundabouts, and unsignalized intersections. Furthermore, DRL-based algorithms are evaluated based on five rationale criteria: driving safety, driving efficiency, training efficiency, unselfishness, and interpretability (DDTUI). Each criterion of DDTUI is specifically analyzed in relation to the reviewed algorithms. Finally, the challenges for future DRL-based decision-making algorithms are summarized.

cs.RO↗