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Zhong Chen

Publications and source records attributed to Zhong Chen.

At least 37 records · Page 2Linked to original sources

Pioplat: A Scalable, Low-Cost Framework for Latency Reduction in Ethereum Blockchain

As decentralized applications on permissionless blockchains are prevalent, more and more latency-sensitive usage scenarios emerged, where the lower the latency of sending and receiving messages, the better the chance of earning revenue. To reduce latency, we present Pioplat, a feasible, customizable, and low-cost latency reduction framework consisting of multiple relay nodes on different continents and at least one instrumented variant of a full node. The node selection strategy of Pioplat and the low-latency communication protocol offer an elastic way to reduce latency effectively. We demonstrate Pioplat's feasibility with an implementation running on five continents and show that Pioplat can significantly reduce the latency of receiving blocks/transactions and sending transactions, thus fulfilling the requirements of most latency-sensitive use cases. Furthermore, we provide the complete implementation of Pioplat to promote further research and allow people to apply the framework to more blockchain systems.

cs.DC↗

An Oversampling-enhanced Multi-class Imbalanced Classification Framework for Patient Health Status Prediction Using Patient-reported Outcomes

Patient-reported outcomes (PROs) directly collected from cancer patients being treated with radiation therapy play a vital role in assisting clinicians in counseling patients regarding likely toxicities. Precise prediction and evaluation of symptoms or health status associated with PROs are fundamental to enhancing decision-making and planning for the required services and support as patients transition into survivorship. However, the raw PRO data collected from hospitals exhibits some intrinsic challenges such as incomplete item reports and imbalance patient toxicities. To the end, in this study, we explore various machine learning techniques to predict patient outcomes related to health status such as pain levels and sleep discomfort using PRO datasets from a cancer photon/proton therapy center. Specifically, we deploy six advanced machine learning classifiers -- Random Forest (RF), XGBoost, Gradient Boosting (GB), Support Vector Machine (SVM), Multi-Layer Perceptron with Bagging (MLP-Bagging), and Logistic Regression (LR) -- to tackle a multi-class imbalance classification problem across three prevalent cancer types: head and neck, prostate, and breast cancers. To address the class imbalance issue, we employ an oversampling strategy, adjusting the training set sample sizes through interpolations of in-class neighboring samples, thereby augmenting minority classes without deviating from the original skewed class distribution. Our experimental findings across multiple PRO datasets indicate that the RF and XGB methods achieve robust generalization performance, evidenced by weighted AUC and detailed confusion matrices, in categorizing outcomes as mild, intermediate, and severe post-radiation therapy. These results underscore the models' effectiveness and potential utility in clinical settings.

cs.LG↗

ContractTinker: LLM-Empowered Vulnerability Repair for Real-World Smart Contracts

Smart contracts are susceptible to being exploited by attackers, especially when facing real-world vulnerabilities. To mitigate this risk, developers often rely on third-party audit services to identify potential vulnerabilities before project deployment. Nevertheless, repairing the identified vulnerabilities is still complex and labor-intensive, particularly for developers lacking security expertise. Moreover, existing pattern-based repair tools mostly fail to address real-world vulnerabilities due to their lack of high-level semantic understanding. To fill this gap, we propose ContractTinker, a Large Language Models (LLMs)-empowered tool for real-world vulnerability repair. The key insight is our adoption of the Chain-of-Thought approach to break down the entire generation task into sub-tasks. Additionally, to reduce hallucination, we integrate program static analysis to guide the LLM. We evaluate ContractTinker on 48 high-risk vulnerabilities. The experimental results show that among the patches generated by ContractTinker, 23 (48%) are valid patches that fix the vulnerabilities, while 10 (21%) require only minor modifications. A video of ContractTinker is available at https://youtu.be/HWFVi-YHcPE.

cs.SE↗

Demystifying and Detecting Cryptographic Defects in Ethereum Smart Contracts

Ethereum has officially provided a set of system-level cryptographic APIs to enhance smart contracts with cryptographic capabilities. These APIs have been utilized in over 10% of Ethereum transactions, motivating developers to implement various on-chain cryptographic tasks, such as digital signatures. However, since developers may not always be cryptographic experts, their ad-hoc and potentially defective implementations could compromise the theoretical guarantees of cryptography, leading to real-world security issues. To mitigate this threat, we conducted the first study aimed at demystifying and detecting cryptographic defects in smart contracts. Through the analysis of 2,406 real-world security reports, we defined nine types of cryptographic defects in smart contracts with detailed descriptions and practical detection patterns. Based on this categorization, we proposed CrySol, a fuzzing-based tool to automate the detection of cryptographic defects in smart contracts. It combines transaction replaying and dynamic taint analysis to extract fine-grained crypto-related semantics and employs crypto-specific strategies to guide the test case generation process. Furthermore, we collected a large-scale dataset containing 25,745 real-world crypto-related smart contracts and evaluated CrySol's effectiveness on it. The result demonstrated that CrySol achieves an overall precision of 95.4% and a recall of 91.2%. Notably, CrySol revealed that 5,847 (22.7%) out of 25,745 smart contracts contain at least one cryptographic defect, highlighting the prevalence of these defects.

cs.CR↗

One for Multiple: Physics-informed Synthetic Data Boosts Generalizable Deep Learning for Fast MRI Reconstruction

Magnetic resonance imaging (MRI) is a widely used radiological modality renowned for its radiation-free, comprehensive insights into the human body, facilitating medical diagnoses. However, the drawback of prolonged scan times hinders its accessibility. The k-space undersampling offers a solution, yet the resultant artifacts necessitate meticulous removal during image reconstruction. Although Deep Learning (DL) has proven effective for fast MRI image reconstruction, its broader applicability across various imaging scenarios has been constrained. Challenges include the high cost and privacy restrictions associated with acquiring large-scale, diverse training data, coupled with the inherent difficulty of addressing mismatches between training and target data in existing DL methodologies. Here, we present a novel Physics-Informed Synthetic data learning framework for Fast MRI, called PISF. PISF marks a breakthrough by enabling generalized DL for multi-scenario MRI reconstruction through a single trained model. Our approach separates the reconstruction of a 2D image into many 1D basic problems, commencing with 1D data synthesis to facilitate generalization. We demonstrate that training DL models on synthetic data, coupled with enhanced learning techniques, yields in vivo MRI reconstructions comparable to or surpassing those of models trained on matched realistic datasets, reducing the reliance on real-world MRI data by up to 96%. Additionally, PISF exhibits remarkable generalizability across multiple vendors and imaging centers. Its adaptability to diverse patient populations has been validated through evaluations by ten experienced medical professionals. PISF presents a feasible and cost-effective way to significantly boost the widespread adoption of DL in various fast MRI applications.

eess.IV↗

FlexDTI: Flexible diffusion gradient encoding scheme-based highly efficient diffusion tensor imaging using deep learning

Objective: Most deep neural network-based diffusion tensor imaging methods require the diffusion gradients' number and directions in the data to be reconstructed to match those in the training data. This work aims to develop and evaluate a novel dynamic-convolution-based method called FlexDTI for highly efficient diffusion tensor reconstruction with flexible diffusion encoding gradient scheme. Approach: FlexDTI was developed to achieve high-quality DTI parametric mapping with flexible number and directions of diffusion encoding gradients. The method used dynamic convolution kernels to embed diffusion gradient direction information into feature maps of the corresponding diffusion signal. Furthermore, it realized the generalization of a flexible number of diffusion gradient directions by setting the maximum number of input channels of the network. The network was trained and tested using datasets from the Human Connectome Project and local hospitals. Results from FlexDTI and other advanced tensor parameter estimation methods were compared. Main results: Compared to other methods, FlexDTI successfully achieves high-quality diffusion tensor-derived parameters even if the number and directions of diffusion encoding gradients change. It reduces normalized root mean squared error (NRMSE) by about 50% on fractional anisotropy (FA) and 15% on mean diffusivity (MD), compared with the state-of-the-art deep learning method with flexible diffusion encoding gradient scheme. Significance: FlexDTI can well learn diffusion gradient direction information to achieve generalized DTI reconstruction with flexible diffusion gradient scheme. Both flexibility and reconstruction quality can be taken into account in this network.

eess.IV↗

When Contracts Meets Crypto: Exploring Developers' Struggles with Ethereum Cryptographic APIs

To empower smart contracts with the promising capabilities of cryptography, Ethereum officially introduced a set of cryptographic APIs that facilitate basic cryptographic operations within smart contracts, such as elliptic curve operations. However, since developers are not necessarily cryptography experts, requiring them to directly interact with these basic APIs has caused real-world security issues and potential usability challenges. To guide future research and solutions to these challenges, we conduct the first empirical study on Ethereum cryptographic practices. Through the analysis of 91,484,856 Ethereum transactions, 500 crypto-related contracts, and 483 StackExchange posts, we provide the first in-depth look at cryptographic tasks developers need to accomplish and identify five categories of obstacles they encounter. Furthermore, we conduct an online survey with 78 smart contract practitioners to explore their perspectives on these obstacles and elicit the underlying reasons. We find that more than half of practitioners face more challenges in cryptographic tasks compared to general business logic in smart contracts. Their feedback highlights the gap between low-level cryptographic APIs and high-level tasks they need to accomplish, emphasizing the need for improved cryptographic APIs, task-based templates, and effective assistance tools. Based on these findings, we provide practical implications for further improvements and outline future research directions.

cs.SE↗

Precessing jet nozzle connecting to a spinning black hole in M87

The nearby radio galaxy M87 offers a unique opportunity to explore the connections between the central supermassive black hole and relativistic jets. Previous studies of the inner region of M87 revealed a wide opening angle for the jet originating near the black hole. The Event Horizon Telescope resolved the central radio source and found an asymmetric ring structure consistent with expectations from General Relativity. With a baseline of 17 years of observations, there was a shift in the jet's transverse position, possibly arising from an eight to ten-year quasi-periodicity. However, the origin of this sideways shift remains unclear. Here we report an analysis of radio observations over 22 years that suggests a period of about 11 years in the position angle variation of the jet. We infer that we are seeing a spinning black hole that induces the Lense-Thirring precession of a misaligned accretion disk. Similar jet precession may commonly occur in other active galactic nuclei but has been challenging to detect owing to the small magnitude and long period of the variation.

astro-ph.HE↗

Non-Uniform Sampling Reconstruction for Symmetrical NMR Spectroscopy by Exploiting Inherent Symmetry

Symmetrical NMR spectroscopy constitutes a vital branch of multidimensional NMR spectroscopy, providing a powerful tool for the structural elucidation of biological macromolecules. Non-Uniform Sampling (NUS) serves as an effective strategy for averting the prohibitive acquisition time of multidimensional NMR spectroscopy by only sampling a few points according to NUS sampling schedules and reconstructing missing points via algorithms. However, current sampling schedules are unable to maintain the accurate recovery of cross peaks that are weak but important. In this work, we propose a novel sampling schedule termed as SCPG (Symmetrical Copy Poisson Gap) and employ CS (Compressed Sensing) methods for reconstruction. We theoretically prove that the symmetrical constraint, apart from sparsity, is implicitly implemented when SCPG is combined with CS methods. The simulated and experimental data substantiate the advantage of SCPG over state-of-the-art 2D Woven PG in the NUS reconstruction of symmetrical NMR spectroscopy.

eess.SP↗

DSC-MRI derived relative CBV maps synthesized from IVIM-MRI data:Application in glioma IDH mutation status identification

Objectives:To develop a framework for obtaining dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) derived relative cerebral blood volume (rCBV) maps without gadolinium-based contrast agent (GBCA) injection. Methods:This retrospective study included 146 patients (124 IDH wildtype; 22 IDH mutation) diagnosed with glioma. The DSC-MRI-derived rCBV maps were synthesized from intravoxel incoherent motion (IVIM) MRI data by the deep neural network trained only with IDH wildtype data due to thedata imbalance. Linear regression analysis, Pearson correlation coefficient, and Bland-Altman analysis, were done to evaluate the consistency between real and synthetic rCBV maps. The generalizability of the proposed framework was evaluated with IDH mutation data. IDH mutation status identification ability of real and synthetic rCBV maps was analyzed and compared using ROC analysis and the DeLong test. Results:Linear regression analysis shows a linear relationship between real and synthetic rCBV maps with a relatively high Pearson correlation coefficient (IDH wildtype: Pearson P = 0.7536; IDH mutation: Pearson P = 0.8933). Bland-Altman analysis between real and synthetic rCBV maps shows that almost all the data distribute within the 95% limits of agreement (IDH wildtype: 19 of 20 [95%]; IDH mutation: 19 of 20 [95%]). ROC analysis and the DeLong test show that the IDH mutation status identification abilities of real (AUC = 0.8375) and synthetic rCBV (AUC = 0.8325) are comparable and show no significant difference (P = 0.9075). Conclusions:It is feasible to obtain DSC-MRI-derived rCBV maps without the injection of GBCA. The synthetic rCBV map shows high consistency with real one.

physics.med-ph↗

Convex Dual Theory Analysis of Two-Layer Convolutional Neural Networks with Soft-Thresholding

Soft-thresholding has been widely used in neural networks. Its basic network structure is a two-layer convolution neural network with soft-thresholding. Due to the network's nature of nonlinearity and nonconvexity, the training process heavily depends on an appropriate initialization of network parameters, resulting in the difficulty of obtaining a globally optimal solution. To address this issue, a convex dual network is designed here. We theoretically analyze the network convexity and numerically confirm that the strong duality holds. This conclusion is further verified in the linear fitting and denoising experiments. This work provides a new way to convexify soft-thresholding neural networks.

cs.LG↗

Overview of the Observing System and Initial Scientific Accomplishments of the East Asian VLBI Network (EAVN)

The East Asian VLBI Network (EAVN) is an international VLBI facility in East Asia and is operated under mutual collaboration between East Asian countries, as well as part of Southeast Asian and European countries. EAVN currently consists of 16 radio telescopes and three correlators located in China, Japan, and Korea, and is operated mainly at three frequency bands, 6.7, 22, and 43 GHz with the longest baseline length of 5078 km, resulting in the highest angular resolution of 0.28 milliarcseconds at 43 GHz. One of distinct capabilities of EAVN is multi-frequency simultaneous data reception at nine telescopes, which enable us to employ the frequency phase transfer technique to obtain better sensitivity at higher observing frequencies. EAVN started its open-use program in the second half of 2018, providing a total observing time of more than 1100 hours in a year. EAVN fills geographical gap in global VLBI array, resulting in enabling us to conduct contiguous high-resolution VLBI observations. EAVN has produced various scientific accomplishments especially in observations toward active galactic nuclei, evolved stars, and star-forming regions. These activities motivate us to initiate launch of the 'Global VLBI Alliance' to provide an opportunity of VLBI observation with the longest baselines on the earth.

astro-ph.IM↗

Detecting the oscillation and propagation of the nascent dynamic solar wind structure at 2.6 solar radii using VLBI radio telescopes

Probing the solar corona is crucial to study the coronal heating and solar wind acceleration. However, the transient and inhomogeneous solar wind flows carry large-amplitude inherent Alfven waves and turbulence, which make detection more difficult. We report the oscillation and propagation of the solar wind at 2.6 solar radii (Rs) by observation of China Tianwen and ESA Mars Express with radio telescopes. The observations were carried out on Oct.9 2021, when one coronal mass ejection (CME) passed across the ray paths of the telescope beams. We obtain the frequency fluctuations (FF) of the spacecraft signals from each individual telescope. Firstly, we visually identify the drift of the frequency spikes at a high spatial resolution of thousands of kilometers along the projected baselines. They are used as traces to estimate the solar wind velocity. Then we perform the cross-correlation analysis on the time series of FF from different telescopes. The velocity variations of solar wind structure along radial and tangential directions during the CME passage are obtained. The oscillation of tangential velocity confirms the detection of streamer wave. Moreover, at the tail of the CME, we detect the propagation of an accelerating fast field-aligned density structure indicating the presence of magnetohydrodynamic waves. This study confirm that the ground station-pairs are able to form particular spatial projection baselines with high resolution and sensitivity to study the detailed propagation of the nascent dynamic solar wind structure.

astro-ph.SR↗

Xscope: Hunting for Cross-Chain Bridge Attacks

Cross-Chain bridges have become the most popular solution to support asset interoperability between heterogeneous blockchains. However, while providing efficient and flexible cross-chain asset transfer, the complex workflow involving both on-chain smart contracts and off-chain programs causes emerging security issues. In the past year, there have been more than ten severe attacks against cross-chain bridges, causing billions of loss. With few studies focusing on the security of cross-chain bridges, the community still lacks the knowledge and tools to mitigate this significant threat. To bridge the gap, we conduct the first study on the security of cross-chain bridges. We document three new classes of security bugs and propose a set of security properties and patterns to characterize them. Based on those patterns, we design Xscope, an automatic tool to find security violations in cross-chain bridges and detect real-world attacks. We evaluate Xscope on four popular cross-chain bridges. It successfully detects all known attacks and finds suspicious attacks unreported before. A video of Xscope is available at https://youtu.be/vMRO_qOqtXY.

cs.SE↗

Model-based Synthetic Data-driven Learning (MOST-DL): Application in Single-shot T2 Mapping with Severe Head Motion Using Overlapping-echo Acquisition

Use of synthetic data has provided a potential solution for addressing unavailable or insufficient training samples in deep learning-based magnetic resonance imaging (MRI). However, the challenge brought by domain gap between synthetic and real data is usually encountered, especially under complex experimental conditions. In this study, by combining Bloch simulation and general MRI models, we propose a framework for addressing the lack of training data in supervised learning scenarios, termed MOST-DL. A challenging application is demonstrated to verify the proposed framework and achieve motion-robust T2 mapping using single-shot overlapping-echo acquisition. We decompose the process into two main steps: (1) calibrationless parallel reconstruction for ultra-fast pulse sequence and (2) intra-shot motion correction for T2 mapping. To bridge the domain gap, realistic textures from a public database and various imperfection simulations were explored. The neural network was first trained with pure synthetic data and then evaluated with in vivo human brain. Both simulation and in vivo experiments show that the MOST-DL method significantly reduces ghosting and motion artifacts in T2 maps in the presence of unpredictable subject movement and has the potential to be applied to motion-prone patients in the clinic.

eess.IV↗

The intrinsic structure of Sagittarius A* at 1.3 cm and 7 mm

Sagittarius A* (Sgr A*), the Galactic Center supermassive black hole (SMBH), is one of the best targets to resolve the innermost region of SMBH with very long baseline interferometry (VLBI). In this study, we have carried out observations toward Sgr A* at 1.349 cm (22.223 GHz) and 6.950 mm (43.135 GHz) with the East Asian VLBI Network, as a part of the multi-wavelength campaign of the Event Horizon Telescope (EHT) in 2017 April. To mitigate scattering effects, the physically motivated scattering kernel model from Psaltis et al. (2018) and the scattering parameters from Johnson et al. (2018) have been applied. As a result, a single, symmetric Gaussian model well describes the intrinsic structure of Sgr A* at both wavelengths. From closure amplitudes, the major-axis sizes are ~704$\pm$102 $μ$as (axial ratio $\sim$1.19$^{+0.24}_{-0.19}$) and $\sim$300$\pm$25 $μ$as (axial ratio $\sim$1.28$\pm$0.2) at 1.349 cm and 6.95 mm respectively. Together with a quasi-simultaneous observation at 3.5 mm (86 GHz) by Issaoun et al. (2019), we show that the intrinsic size scales with observing wavelength as a power-law, with an index $\sim$1.2$\pm$0.2. Our results also provide estimates of the size and compact flux density at 1.3 mm, which can be incorporated into the analysis of the EHT observations. In terms of the origin of radio emission, we have compared the intrinsic structures with the accretion flow scenario, especially the radiatively inefficient accretion flow based on the Keplerian shell model. With this, we show that a nonthermal electron population is necessary to reproduce the source sizes.

astro-ph.HE↗

VOLKS2: a transient search and localization pipeline for VLBI observations

We present VOLKS2, the second release of "VLBI Observation for transient Localization Keen Searcher". The pipeline aims at transient search in regular VLBI observations as well as detection of single pulses from known sources in dedicated VLBI observations. The underlying method takes the idea of geodetic VLBI data processing, including fringe fitting to maximize the signal power and geodetic VLBI solving for localization. By filtering the candidate signals with multiple windows within a baseline and by cross matching with multiple baselines, RFIs are eliminated effectively. Unlike the station auto spectrum based method, RFI flagging is not required in the VOLKS2 pipeline. EVN observation (EL060) is carried out, so as to verify the pipeline's detection efficiency and localization accuracy in the whole FoV. The pipeline is parallelized with MPI and further accelerated with GPU, so as to exploit the hardware resources of modern GPU clusters. We can prove that, with proper optimization, VOLKS2 could achieve comparable performance as auto spectrum based pipelines. All the code and documents are publicly available, in the hope that our pipeline is useful for radio transient studies.

astro-ph.IM↗

VLBI data processing on coronal radio-sounding experiments of Mars express

The ESA's Mars Express solar corona experiments were performed at two solar conjunctions in the years 2015 and 2017 by a number of radio telescopes in the European VLBI Network. This paper presents the methods to measure the frequency and phase fluctuations of the spacecraft radio signal, and the applications to study the characteristics of the plasma turbulence effects on the signal at a single station and at multiple stations via cross-correlation. The power spectra of the frequency fluctuations observed between 4.9 and 76.3 $\rm R_{s}$ have a power-law shape close to a Kolmogorov spectrum over the frequency interval $ ν_{lo}< ν<ν_{up}$, where the nominal value of $ν_{lo}$ is set to 3 mHz and $ν_{up}$ is in the range of 0.03 $\sim$ 0.15 Hz. The RMS of the frequency fluctuations is presented as a function of the heliocentric distance. Furthermore, we analyse the variations of the electron column density fluctuations at solar offsets 4.9 $\rm{R_{s}}$ and 9.9 $\rm{R_{s}}$ and the cross-correlation products between the VLBI stations. The power density of the differential fluctuations between different stations decreases at $ν< 0.01$ Hz. Finally, the fast flow speeds of solar wind $>700$ $\rm{km~s^{-1}}$ are derived from the cross-correlation of frequency fluctuations at $ν< 0.01$ Hz. The fast flow speeds of solar wind correspond to the high heliolatitude of the coronal region that the radio rays passed. The VLBI observations and analysis methods can be used to study the electron column density fluctuations and the turbulence at multiple spatial points in the inner solar wind by providing multiple lines of sight between the Earth and the spacecraft.

astro-ph.IM↗