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arXiv · 1506.07215

A quantum mechanical scheme to reduce radiation damage in electron microscopy

Hiroshi Okamoto·Tatiana Latychevskaia·Hans-Werner Fink
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Abstract

We show that radiation damage to unstained biological specimens is not an intractable problem in electron microscopy. When a structural hypothesis of a specimen is available, quantum mechanical principles allow us to verify the hypothesis with a very low electron dose. Realization of such a concept requires precise control of the electron wave front. Based on a diffractive electron optical implementation, we demonstrate the feasibility of this new method by both experimental and numerical investigations.

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Hiroshi Okamoto, Tatiana Latychevskaia, Hans-Werner Fink. 2015-06-24. A quantum mechanical scheme to reduce radiation damage in electron microscopy. https://doi.org/10.1063/1.2191096

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