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arXiv · 2310.09207

Four-Dimensional Computational Ultrasound Imaging of Brain Haemodynamics

Michael D. Brown·Bastian S. Generowicz·Stephanie Dijkhuizen·Sebastiaan K. E. Koekkoek·Christos Strydis·Johannes G. Bosch·Petros Arvanitis·Geert Springeling·Geert J. T. Leus·Chris I. De Zeeuw·Pieter Kruizinga
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Abstract

Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), a new imaging method that uses complex ultrasound fields that can be generated with simple hardware and a physical wave prediction model to alleviate the sampling constraints. cUSi allows for high-resolution four-dimensional imaging of brain haemodynamics in awake and anesthetized mice.

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Michael D. Brown, Bastian S. Generowicz, Stephanie Dijkhuizen, Sebastiaan K. E. Koekkoek, Christos Strydis, Johannes G. Bosch, Petros Arvanitis, Geert Springeling, Geert J. T. Leus, Chris I. De Zeeuw, Pieter Kruizinga. 2023-10-13. Four-Dimensional Computational Ultrasound Imaging of Brain Haemodynamics. https://arxiv.org/abs/2310.09207

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