Radionuclide Production for Dose Verification in VHEE FLASH Radiotherapy

Francesco Urso; Federica Baffigi; Esther Ciarrocchi; Leonida Antonio Gizzi; Petra Koester; Luca Labate; Matteo Morrocchi; Simona Piccinini; Martina Salvadori; Maria Giuseppina Bisogni

arXiv · 2505.21183

Radionuclide Production for Dose Verification in VHEE FLASH Radiotherapy

Francesco Urso·Federica Baffigi·Esther Ciarrocchi·Leonida Antonio Gizzi·Petra Koester·Luca Labate·Matteo Morrocchi·Simona Piccinini·Martina Salvadori·Maria Giuseppina Bisogni

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Abstract

This study explores the production of radionuclides in a PMMA (Polymethylmethacrylate) phantom irradiated with Very High Energy Electrons (VHEE) beams as a novel method for dose verification. In this work, Monte Carlo simulation studies using the Geant4 toolkit and experimental measurements with a VHEE beam produced by a laser-plasma accelerator were conducted. Specifically, the photonuclear production of 11C, 15O and 13N is examined, with a detailed analysis of their spatial distribution, production yields and decay time

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Francesco Urso, Federica Baffigi, Esther Ciarrocchi, Leonida Antonio Gizzi, Petra Koester, Luca Labate, Matteo Morrocchi, Simona Piccinini, Martina Salvadori, Maria Giuseppina Bisogni. 2025-05-27. Radionuclide Production for Dose Verification in VHEE FLASH Radiotherapy. https://arxiv.org/abs/2505.21183

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