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arXiv · 2605.16679

CHI-Bench: Can AI Agents Automate End-to-End, Long-Horizon, Policy-Rich Healthcare Workflows?

Abstract

End-to-end automation of realistic healthcare operations stresses three capabilities underrepresented in current benchmarks: policy density, decisions must be grounded in a large library of medical, insurance, and operational rules; Multi-role composition: a single task requires the agent to play multiple roles with handoffs; and multilateral interaction: intermediate workflow steps are multi-turn dialogs, such as peer-to-peer review and patient outreach. We introduce $\chi$-Bench, a benchmark of long-horizon healthcare workflows across three domains: provider prior authorization, payer utilization management, and care management. Each task hands the agent a clinical case in a high-fidelity simulator of 20 healthcare apps exposed via 87 MCP tools, which it must drive to a terminal status through tool calls and writing the role's artifacts, guided by a 1,290+ document managed-care operations handbook skill. Across 30 agent harness/models configurations, the best agent resolves only 28.0% of tasks, no agent clears 20% on strict pass^3, and executing all tasks in a single session slumps the performance to 3.8%. These results raise the hypothesis that similar gaps are likely to surface in other policy-dense, role-composed, irreversible enterprise domains.

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Haolin Chen, Deon Metelski, Leon Qi, Tao Xia, Joonyul Lee, Steve Brown, Kevin Riley, Frank Wang, T. Y. Alvin Liu, Hank Capps MD, Zeyu Tang, Xiangchen Song, Lingjing Kong, Fan Feng, Tianyi Zeng, Zhiwei Liu, Zixian Ma, Hang Jiang, Fangli Geng, Yuan Yuan, Chenyu You, Qingsong Wen, Hua Wei, Yanjie Fu, Yue Zhao, Carl Yang, Biwei Huang, Kun Zhang, Caiming Xiong, Sanmi Koyejo, Eric P. Xing, Philip S. Yu, Weiran Yao. 2026-05-15. CHI-Bench: Can AI Agents Automate End-to-End, Long-Horizon, Policy-Rich Healthcare Workflows?. https://arxiv.org/abs/2605.16679

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