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arXiv · cond-mat/9701075

A hierarchical scheme for cooperativity and folding in proteins

Alex Hansen·Mogens H. Jensen·Kim Sneppen·Giovanni Zocchi
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Abstract

We propose a protein model based on a hierarchy of constraints that force the protein to follow certain pathways when changing conformation. The model exhibits a first order phase transition, cooperativity and is exactly solvable. It also shows an unexpected symmetry between folding and unfolding pathways as suggested by a recent experiment.

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Alex Hansen, Mogens H. Jensen, Kim Sneppen, Giovanni Zocchi. 1998-01-14. A hierarchical scheme for cooperativity and folding in proteins. https://doi.org/10.1016/s0378-4371(97)00567-0

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