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In-Vivo NMR of Hyperpolarized Helium-3 in the Human Lung at Very Low Magnetic Fields

Christopher P. Bidinosti·Jamal Choukeife·Pierre-Jean Nacher·Geneviève Tastevin
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Abstract

We present NMR measurements of the diffusion of hyperpolarized helium-3 in the human lung performed at fields much lower than those of conventional MRI scanners. The measurements were made on standing subjects using homebuilt apparatus operating at 3 mT. Oxygen-limited transverse relaxation (T2 up to 15-35 s) could be measured in-vivo. Accurate global diffusion measurements have been performed in-vivo and in-vitro. 1D ADC mapping with high SNR demonstrates the real possibility of performing quality lung imaging at extremely low fields.

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Christopher P. Bidinosti, Jamal Choukeife, Pierre-Jean Nacher, Geneviève Tastevin. 2003-01-20. In-Vivo NMR of Hyperpolarized Helium-3 in the Human Lung at Very Low Magnetic Fields. https://doi.org/10.1016/s1090-7807(02)00198-2

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