arXiv subjects

H. C. Rosu

Publications and source records attributed to H. C. Rosu.

At least 73 records · Page 4Linked to original sources

arXiv2007

High-gain nonlinear observer for simple genetic regulation process

High-gain nonlinear observers occur in the nonlinear automatic control theory and are in standard usage in chemical engineering processes. We apply such a type of analysis in the context of a very simple one-gene regulation circuit. In general, an observer combines an analytical differential-equation-based model with partial measurement of the system in order to estimate the non-measured state variables. We use one of the simplest observers, that of Gauthier et al., which is a copy of the original system plus a correction term which is easy to calculate. For the illustration of this procedure, we employ a biological model, recently adapted from Goodwin's old book by De Jong, in which one plays with the dynamics of the concentrations of the messenger RNA coding for a given protein, the protein itself, and a single metabolite. Using the observer instead of the metabolite, it is possible to rebuild the non-measured concentrations of the mRNA and the protein

q-bio.QM↗

arXiv2007

Supersymmetric methods in the traveling variable: inside neurons and at the brain scale

We apply the mathematical technique of factorization of differential operators to two different problems. First we review our results related to the supersymmetry of the Montroll kinks moving onto the microtubule walls as well as mentioning the sine-Gordon model for the microtubule nonlinear excitations. Second, we find analytic expressions for a class of one-parameter solutions of a sort of diffusion equation of Bessel type that is obtained by supersymmetry from the homogeneous form of a simple damped wave equations derived in the works of P.A. Robinson and collaborators for the corticothalamic system. We also present a possible interpretation of the diffusion equation in the brain context

physics.bio-ph↗

arXiv2007

The microtubule transistor

I point out the similarity between the microtubule experiment reported by Priel et al [Biophys. J. 90, 4639 (2006)] and the ZnO nanowire experiment of Wang et al [Nanolett. 6, 2768 (2006)]. It is quite possible that MTs are similar to a piezoelectric field effect transistor for which the role of the control gate electrode is played by the piezo-induced electric field across the width of the MT walls and their elastic bending features

q-bio.SC↗

arXiv2007

Stationary states in a potential well

We review here in a historical context the topic of stationary states in the quantum world, including the generalization to the primary ideas. We also discuss the stationary states in one dimensional parabolic wells and the three dimensional Coulomb and parabolic cases, as well as the stationary bound states in the continuum

quant-ph↗

arXiv2007

FRW barotropic zero modes: Dynamical systems observability

The dynamical systems observability properties of barotropic bosonic and fermionic FRW cosmological oscillators are investigated. Nonlinear techniques for dynamical analysis have been recently developed in many engineering areas but their application has not been extended beyond their standard field. This paper is a small contribution to an extension of this type of dynamical systems analysis to FRW barotropic cosmologies. We find that determining the Hubble parameter of barotropic FRW universes does not allow the observability, i.e., the determination of neither the barotropic FRW zero mode nor of its derivative as dynamical cosmological states. Only knowing the latter ones correspond to a rigorous dynamical observability in barotropic cosmology

gr-qc↗

arXiv2007

Inferring mixed-culture growth from total biomass data in a wavelet approach

It is shown that the presence of mixed-culture growth in batch fermentation processes can be very accurately inferred from total biomass data by means of the wavelet analysis for singularity detection. This is accomplished by considering simple phenomenological models for the mixed growth and the more complicated case of mixed growth on a mixture of substrates. The main quantity provided by the wavelet analysis is the Holder exponent of the singularity that we determine for our illustrative examples. The numerical results point to the possibility that Holder exponents can be used to characterize the nature of the mixed-culture growth in batch fermentation processes with potential industrial applications. Moreover, the analysis of the same data affected by the common additive Gaussian noise still lead to the wavelet detection of the singularities although the Holder exponent is no longer a useful parameter

physics.bio-ph↗

arXiv2006

Shape invariance through Crum transformation

We show in a rigorous way that Crum's result on equal eigenvalue spectrum of Sturm-Liouville problems can be obtained iteratively by successive Darboux transformations. It can be shown that all neighbouring Darboux-transformed potentials of higher order, u_{k} and u_{k+1}, satisfy the condition of shape invariance provided the original potential u does. We use this result to proof that under the condition of shape invariance the n-th iteration of the original Sturm-Liouville problem defined through shape invariance is equal to the n-th Crum transformation

math-ph↗

arXiv2006

Genetic algorithm optimization of entanglement

We present an application of a genetic algorithmic computational method to the optimization of the concurrence measure of entanglement for the cases of one dimensional chains, as well as square and triangular lattices in a simple tight-binding approach in which the hopping of electrons is much stronger than the phonon dissipation

quant-ph↗

arXiv2006

Cellular Automata Modeling of Continuous Stirred Tank Reactors

The classical dynamical systems model of continuous stirred tank reactors (CSTR) in which a first order chemical reaction takes place is reformulated in terms of stochastic cellular automata by extending previous works of Seyborg (1997) and Neuforth (2000) by including the feed flow of chemical reactants. We show that this cellular automata procedure is able to simulate the dilution rate and the mixing process in the CSTR, as well as the details of the heat removal due to the jacket. The cellular automata approach is expected to be of considerable applicability at any industrial scales and especially for any type of microchemical systems

nlin.CG↗

arXiv2006

PI-controlled bioreactor as a generalized Lienard system

It is shown that periodic orbits can occur in Cholette's bioreactor model working under the influence of a PI-controller. We find a diffeomorphic coordinate transformation that turns this controlled enzymatic reaction system into a generalized Lienard form. Furthermore, we give sufficient conditions for the existence and uniqueness of limit cycles in the new coordinates. We also perform numerical simulations illustrating the possibility of the existence of a local center (period annulus). A result with possible practical applications is that the oscillation frequency is a function of the integral control gain parameter

nlin.CD↗

arXiv2006

Travelling-wave solutions for Korteweg-de Vries-Burgers equations through factorizations

Travelling-wave solutions of the standard and compound form of Korteweg-de Vries-Burgers equations are found using factorizations of the corresponding reduced ordinary differential equations. The procedure leads to solutions of Bernoulli equations of nonlinearity 3/2 and 2 (Riccati), respectively. Introducing the initial conditions through an imaginary phase in the travelling coordinate, we obtain all the solutions previously reported, some of them being corrected here, and showing, at the same time, the presence of interesting details of these solitary waves that have been overlooked before this investigation

math-ph↗

arXiv2006

Self-image effects for diffraction and dispersion

Excerpt: We apply the wavelet transform to the fractal Talbot effect in both diffraction and fiber dispersion. In the first case, the self similar character of the transverse paraxial field at irrational multiples of the Talbot distance is confirmed, whereas in the second case it is shown that the field is not self similar for supergaussian pulses. Finally, a high-precision measurement of irrational distances employing the fractal index determined with the wavelet transform is pointed out

physics.optics↗

arXiv2006

Niederhauser's model for epilepsy and wavelet methods

Wavelets and wavelet transforms (WT) could be a very useful tool to analyze electroencephalogram (EEG) signals. To illustrate the WT method we make use of a simple electric circuit model introduced by Niederhauser, which is used to produce EEG-like signals, particularly during an epileptic seizure. The original model is modified to resemble the 10-20 derivation of the EEG measurements. WT is used to study the main features of these signals

physics.med-ph↗

arXiv2006

Robust estimation of the exponent function in the Gompertz law

The estimation of the solution of a system of two differential equations introduced by Norton (1976) that is equivalent to the Gompertz law is performed by means of the recent adaptive scheme of Besancon and collaborators (2004). Results of computer simulations illustrate the robustness of the approach

physics.comp-ph↗

arXiv2005

Mutually unbiased phase states, phase uncertainties, and Gauss sums

Mutually unbiased bases (MUBs), which are such that the inner product between two vectors in different orthogonal bases is a constant equal to 1/sqrt{d), with d the dimension of the finite Hilbert space, are becoming more and more studied for applications such as quantum tomography and cryptography, and in relation to entangled states and to the Heisenberg-Weil group of quantum optics. Complete sets of MUBs of cardinality d+1 have been derived for prime power dimensions d=p^m using the tools of abstract algebra. Presumably, for non prime dimensions the cardinality is much less. Here we reinterpret MUBs as quantum phase states, i.e. as eigenvectors of Hermitean phase operators generalizing those introduced by Pegg & Barnett in 1989. We relate MUB states to additive characters of Galois fields (in odd characteristic p) and to Galois rings (in characteristic 2). Quantum Fourier transforms of the components in vectors of the bases define a more general class of MUBs with multiplicative characters and additive ones altogether. We investigate the complementary properties of the above phase operator with respect to the number operator. We also study the phase probability distribution and variance for general pure quantum electromagnetic states and find them to be related to the Gauss sums, which are sums over all elements of the field (or of the ring) of the product of multiplicative and additive characters. Finally, we relate the concepts of mutual unbiasedness and maximal entanglement. This allows to use well studied algebraic concepts as efficient tools in the study of entanglement and its information aspects

quant-ph↗

arXiv2005

Talbot effect for dispersion in linear optical fibers and a wavelet approach

We shortly recall the mathematical and physical aspects of Talbot's self-imaging effect occurring in near-field diffraction. In the rational paraxial approximation, the Talbot images are formed at distances z=p/q, where p and q are coprimes, and are superpositions of q equally spaced images of the original binary transmission (Ronchi) grating. This interpretation offers the possibility to express the Talbot effect through Gauss sums. Here, we pay attention to the Talbot effect in the case of dispersion in optical fibers presenting our considerations based on the close relationships of the mathematical representations of diffraction and dispersion. Although dispersion deals with continuous functions, such as gaussian and supergaussian pulses, whereas in diffraction one frequently deals with discontinuous functions, the mathematical correspondence enables one to characterize the Talbot effect in the two cases with minor differences. In addition, we apply, for the first time to our knowledge, the wavelet transform to the fractal Talbot effect in both diffraction and fiber dispersion. In the first case, the self similar character of the transverse paraxial field at irrational multiples of the Talbot distance is confirmed, whereas in the second case it is shown that the field is not self similar for supergaussian pulses. Finally, a high-precision measurement of irrational distances employing the fractal index determined with the wavelet transform is pointed out

physics.optics↗

arXiv2005

Supersymmetry of FRW barotropic cosmologies

Barotropic FRW cosmologies are presented from the standpoint of nonrelativistic supersymmetry. First, we reduce the barotropic FRW system of differential equations to simple harmonic oscillator differential equations. Employing the factorization procedure, the solutions of the latter equations are divided into the two classes of bosonic (nonsingular) and fermionic (singular) cosmological solutions. We next introduce a coupling parameter denoted by K between the two classes of solutions and obtain barotropic cosmologies with dissipative features acting on the scale factors and spatial curvature of the universe. The K-extended FRW equations in comoving time are presented in explicit form in the low coupling regime. The standard barotropic FRW cosmologies correspond to the dissipationless limit K =0

gr-qc↗

arXiv2005

Nonlinear software sensor for monitoring genetic regulation processes with noise and modeling errors

Nonlinear control techniques by means of a software sensor that are commonly used in chemical engineering could be also applied to genetic regulation processes. We provide here a realistic formulation of this procedure by introducing an additive white Gaussian noise, which is usually found in experimental data. Besides, we include model errors, meaning that we assume we do not know the nonlinear regulation function of the process. In order to illustrate this procedure, we employ the Goodwin dynamics of the concentrations [B.C. Goodwin, Temporal Oscillations in Cells, (Academic Press, New York, 1963)] in the simple form recently applied to single gene systems and some operon cases [H. De Jong, J. Comp. Biol. 9, 67 (2002)], which involves the dynamics of the mRNA, given protein, and metabolite concentrations. Further, we present results for a three gene case in co-regulated sets of transcription units as they occur in prokaryotes. However, instead of considering their full dynamics, we use only the data of the metabolites and a designed software sensor. We also show, more generally, that it is possible to rebuild the complete set of nonmeasured concentrations despite the uncertainties in the regulation function or, even more, in the case of not knowing the mRNA dynamics. In addition, the rebuilding of concentrations is not affected by the perturbation due to the additive white Gaussian noise and also we managed to filter the noisy output of the biological system

physics.bio-ph↗