arXiv subjects

Hao Chen

Publications and source records attributed to Hao Chen.

At least 811 records · Page 45Linked to original sources

arXiv2024

Floating Anchor Diffusion Model for Multi-motif Scaffolding

Motif scaffolding seeks to design scaffold structures for constructing proteins with functions derived from the desired motif, which is crucial for the design of vaccines and enzymes. Previous works approach the problem by inpainting or conditional generation. Both of them can only scaffold motifs with fixed positions, and the conditional generation cannot guarantee the presence of motifs. However, prior knowledge of the relative motif positions in a protein is not readily available, and constructing a protein with multiple functions in one protein is more general and significant because of the synergies between functions. We propose a Floating Anchor Diffusion (FADiff) model. FADiff allows motifs to float rigidly and independently in the process of diffusion, which guarantees the presence of motifs and automates the motif position design. Our experiments demonstrate the efficacy of FADiff with high success rates and designable novel scaffolds. To the best of our knowledge, FADiff is the first work to tackle the challenge of scaffolding multiple motifs without relying on the expertise of relative motif positions in the protein. Code is available at https://github.com/aim-uofa/FADiff.

q-bio.BM↗

arXiv2024

Post-hoc Part-prototype Networks

Post-hoc explainability methods such as Grad-CAM are popular because they do not influence the performance of a trained model. However, they mainly reveal "where" a model looks at for a given input, fail to explain "what" the model looks for (e.g., what is important to classify a bird image to a Scott Oriole?). Existing part-prototype networks leverage part-prototypes (e.g., characteristic Scott Oriole's wing and head) to answer both "where" and "what", but often under-perform their black box counterparts in the accuracy. Therefore, a natural question is: can one construct a network that answers both "where" and "what" in a post-hoc manner to guarantee the model's performance? To this end, we propose the first post-hoc part-prototype network via decomposing the classification head of a trained model into a set of interpretable part-prototypes. Concretely, we propose an unsupervised prototype discovery and refining strategy to obtain prototypes that can precisely reconstruct the classification head, yet being interpretable. Besides guaranteeing the performance, we show that our network offers more faithful explanations qualitatively and yields even better part-prototypes quantitatively than prior part-prototype networks.

cs.CV↗

arXiv2024

KnowGPT: Knowledge Graph based Prompting for Large Language Models

Large Language Models (LLMs) have demonstrated remarkable capabilities in many real-world applications. Nonetheless, LLMs are often criticized for their tendency to produce hallucinations, wherein the models fabricate incorrect statements on tasks beyond their knowledge and perception. To alleviate this issue, researchers have explored leveraging the factual knowledge in knowledge graphs (KGs) to ground the LLM's responses in established facts and principles. However, most state-of-the-art LLMs are closed-source, making it challenging to develop a prompting framework that can efficiently and effectively integrate KGs into LLMs with hard prompts only. Generally, existing KG-enhanced LLMs usually suffer from three critical issues, including huge search space, high API costs, and laborious prompt engineering, that impede their widespread application in practice. To this end, we introduce a novel Knowledge Graph based PrompTing framework, namely KnowGPT, to enhance LLMs with domain knowledge. KnowGPT contains a knowledge extraction module to extract the most informative knowledge from KGs, and a context-aware prompt construction module to automatically convert extracted knowledge into effective prompts. Experiments on three benchmarks demonstrate that KnowGPT significantly outperforms all competitors. Notably, KnowGPT achieves a 92.6% accuracy on OpenbookQA leaderboard, comparable to human-level performance.

cs.CL↗

arXiv2024

Domain Game: Disentangle Anatomical Feature for Single Domain Generalized Segmentation

Single domain generalization aims to address the challenge of out-of-distribution generalization problem with only one source domain available. Feature distanglement is a classic solution to this purpose, where the extracted task-related feature is presumed to be resilient to domain shift. However, the absence of references from other domains in a single-domain scenario poses significant uncertainty in feature disentanglement (ill-posedness). In this paper, we propose a new framework, named \textit{Domain Game}, to perform better feature distangling for medical image segmentation, based on the observation that diagnostic relevant features are more sensitive to geometric transformations, whilist domain-specific features probably will remain invariant to such operations. In domain game, a set of randomly transformed images derived from a singular source image is strategically encoded into two separate feature sets to represent diagnostic features and domain-specific features, respectively, and we apply forces to pull or repel them in the feature space, accordingly. Results from cross-site test domain evaluation showcase approximately an ~11.8% performance boost in prostate segmentation and around ~10.5% in brain tumor segmentation compared to the second-best method.

cs.CV↗

arXiv2024

Generative Active Learning for Long-tailed Instance Segmentation

Recently, large-scale language-image generative models have gained widespread attention and many works have utilized generated data from these models to further enhance the performance of perception tasks. However, not all generated data can positively impact downstream models, and these methods do not thoroughly explore how to better select and utilize generated data. On the other hand, there is still a lack of research oriented towards active learning on generated data. In this paper, we explore how to perform active learning specifically for generated data in the long-tailed instance segmentation task. Subsequently, we propose BSGAL, a new algorithm that online estimates the contribution of the generated data based on gradient cache. BSGAL can handle unlimited generated data and complex downstream segmentation tasks effectively. Experiments show that BSGAL outperforms the baseline approach and effectually improves the performance of long-tailed segmentation. Our code can be found at https://github.com/aim-uofa/DiverGen.

cs.CV↗

arXiv2024

Nature of long-lived moiré interlayer excitons in electrically tunable MoS$_{2}$/MoSe$_{2}$ heterobilayers

Interlayer excitons in transition-metal dichalcogenide heterobilayers combine high binding energy and valley-contrasting physics with long optical lifetime and strong dipolar character. Their permanent electric dipole enables electric-field control of emission energy, lifetime, and location. Device material and geometry impacts the nature of the interlayer excitons via their real- and momentum-space configurations. Here, we show that interlayer excitons in MoS$_{2}$/MoSe$_{2}$ heterobilayers are formed by charge carriers residing at the Brillouin zone edges, with negligible interlayer hybridization. We find that the moiré superlattice leads to the reversal of the valley-dependent optical selection rules, yielding a positively valued g-factor and cross-polarized photoluminescence. Time-resolved photoluminescence measurements reveal that the interlayer exciton population retains the optically induced valley polarization throughout its microsecond-long lifetime. The combination of long optical lifetime and valley polarization retention makes MoS$_{2}$/MoSe$_{2}$ heterobilayers a promising platform for studying fundamental bosonic interactions and developing excitonic circuits for optical information processing.

cond-mat.mes-hall↗

arXiv2024

FreeTumor: Advance Tumor Segmentation via Large-Scale Tumor Synthesis

AI-driven tumor analysis has garnered increasing attention in healthcare. However, its progress is significantly hindered by the lack of annotated tumor cases, which requires radiologists to invest a lot of effort in collecting and annotation. In this paper, we introduce a highly practical solution for robust tumor synthesis and segmentation, termed FreeTumor, which refers to annotation-free synthetic tumors and our desire to free patients that suffering from tumors. Instead of pursuing sophisticated technical synthesis modules, we aim to design a simple yet effective tumor synthesis paradigm to unleash the power of large-scale data. Specifically, FreeTumor advances existing methods mainly from three aspects: (1) Existing methods only leverage small-scale labeled data for synthesis training, which limits their ability to generalize well on unseen data from different sources. To this end, we introduce the adversarial training strategy to leverage large-scale and diversified unlabeled data in synthesis training, significantly improving tumor synthesis. (2) Existing methods largely ignored the negative impact of low-quality synthetic tumors in segmentation training. Thus, we employ an adversarial-based discriminator to automatically filter out the low-quality synthetic tumors, which effectively alleviates their negative impact. (3) Existing methods only used hundreds of cases in tumor segmentation. In FreeTumor, we investigate the data scaling law in tumor segmentation by scaling up the dataset to 11k cases. Extensive experiments demonstrate the superiority of FreeTumor, e.g., on three tumor segmentation benchmarks, average $+8.9\%$ DSC over the baseline that only using real tumors and $+6.6\%$ DSC over the state-of-the-art tumor synthesis method. Code will be available.

cs.CV↗

arXiv2024

FNP: Fourier Neural Processes for Arbitrary-Resolution Data Assimilation

Data assimilation is a vital component in modern global medium-range weather forecasting systems to obtain the best estimation of the atmospheric state by combining the short-term forecast and observations. Recently, AI-based data assimilation approaches have attracted increasing attention for their significant advantages over traditional techniques in terms of computational consumption. However, existing AI-based data assimilation methods can only handle observations with a specific resolution, lacking the compatibility and generalization ability to assimilate observations with other resolutions. Considering that complex real-world observations often have different resolutions, we propose the \textit{\textbf{Fourier Neural Processes}} (FNP) for \textit{arbitrary-resolution data assimilation} in this paper. Leveraging the efficiency of the designed modules and flexible structure of neural processes, FNP achieves state-of-the-art results in assimilating observations with varying resolutions, and also exhibits increasing advantages over the counterparts as the resolution and the amount of observations increase. Moreover, our FNP trained on a fixed resolution can directly handle the assimilation of observations with out-of-distribution resolutions and the observational information reconstruction task without additional fine-tuning, demonstrating its excellent generalization ability across data resolutions as well as across tasks.

cs.LG↗

arXiv2024

Orbital-Dependent Electron Correlation in Double-Layer Nickelate La3Ni2O7

The latest discovery of high temperature superconductivity near 80K in La3Ni2O7 under high pressure has attracted much attention. Many proposals are put forth to understand the origin of superconductivity.The determination of electronic structures is a prerequisite to establish theories to understand superconductivity in nickelates but is still lacking. Here we report our direct measurement of the electronic structures of La3Ni2O7 by high-resolution angle resolved photoemission spectroscopy. The Fermi surface and band structures of La3Ni2O7 are observed and compared with the band structure calculations. Strong electron correlations are revealed which are orbital- and momentum dependent. A flat band is formed from the Ni-3dz2 orbitals around the zone corner which is ~50meV below the Fermi level and exhibits the strongest electron correlation. In many theoretical proposals, this band is expected to play the dominant role in generating superconductivity in La3Ni2O7. Our observations provide key experimental information to understand the electronic structure and origin of high temperature superconductivity in La3Ni2O7.

cond-mat.supr-con↗

arXiv2024

RTGen: Generating Region-Text Pairs for Open-Vocabulary Object Detection

Open-vocabulary object detection (OVD) requires solid modeling of the region-semantic relationship, which could be learned from massive region-text pairs. However, such data is limited in practice due to significant annotation costs. In this work, we propose RTGen to generate scalable open-vocabulary region-text pairs and demonstrate its capability to boost the performance of open-vocabulary object detection. RTGen includes both text-to-region and region-to-text generation processes on scalable image-caption data. The text-to-region generation is powered by image inpainting, directed by our proposed scene-aware inpainting guider for overall layout harmony. For region-to-text generation, we perform multiple region-level image captioning with various prompts and select the best matching text according to CLIP similarity. To facilitate detection training on region-text pairs, we also introduce a localization-aware region-text contrastive loss that learns object proposals tailored with different localization qualities. Extensive experiments demonstrate that our RTGen can serve as a scalable, semantically rich, and effective source for open-vocabulary object detection and continue to improve the model performance when more data is utilized, delivering superior performance compared to the existing state-of-the-art methods.

cs.CV↗

arXiv2024

Prompt Fuzzing for Fuzz Driver Generation

Crafting high-quality fuzz drivers not only is time-consuming but also requires a deep understanding of the library. However, the state-of-the-art automatic fuzz driver generation techniques fall short of expectations. While fuzz drivers derived from consumer code can reach deep states, they have limited coverage. Conversely, interpretative fuzzing can explore most API calls but requires numerous attempts within a large search space. We propose PromptFuzz, a coverage-guided fuzzer for prompt fuzzing that iteratively generates fuzz drivers to explore undiscovered library code. To explore API usage in fuzz drivers during prompt fuzzing, we propose several key techniques: instructive program generation, erroneous program validation, coverage-guided prompt mutation, and constrained fuzzer scheduling. We implemented PromptFuzz and evaluated it on 14 real-world libraries. Compared with OSS-Fuzz and Hopper (the state-of-the-art fuzz driver generation tool), fuzz drivers generated by PromptFuzz achieved 1.61 and 1.63 times higher branch coverage than those by OSS-Fuzz and Hopper, respectively. Moreover, the fuzz drivers generated by PromptFuzz detected 33 genuine, new bugs out of a total of 49 crashes, out of which 30 bugs have been confirmed by their respective communities.

cs.CR↗

arXiv2024

You've Got to Feel It To Believe It: Multi-Modal Bayesian Inference for Semantic and Property Prediction

Robots must be able to understand their surroundings to perform complex tasks in challenging environments and many of these complex tasks require estimates of physical properties such as friction or weight. Estimating such properties using learning is challenging due to the large amounts of labelled data required for training and the difficulty of updating these learned models online at run time. To overcome these challenges, this paper introduces a novel, multi-modal approach for representing semantic predictions and physical property estimates jointly in a probabilistic manner. By using conjugate pairs, the proposed method enables closed-form Bayesian updates given visual and tactile measurements without requiring additional training data. The efficacy of the proposed algorithm is demonstrated through several hardware experiments. In particular, this paper illustrates that by conditioning semantic classifications on physical properties, the proposed method quantitatively outperforms state-of-the-art semantic classification methods that rely on vision alone. To further illustrate its utility, the proposed method is used in several applications including to represent affordance-based properties probabilistically and a challenging terrain traversal task using a legged robot. In the latter task, the proposed method represents the coefficient of friction of the terrain probabilistically, which enables the use of an on-line risk-aware planner that switches the legged robot from a dynamic gait to a static, stable gait when the expected value of the coefficient of friction falls below a given threshold. Videos of these case studies as well as the open-source C++ and ROS interface can be found at https://roahmlab.github.io/multimodal_mapping/.

cs.RO↗

arXiv2024

SFANet: Spatial-Frequency Attention Network for Weather Forecasting

Weather forecasting plays a critical role in various sectors, driving decision-making and risk management. However, traditional methods often struggle to capture the complex dynamics of meteorological systems, particularly in the presence of high-resolution data. In this paper, we propose the Spatial-Frequency Attention Network (SFANet), a novel deep learning framework designed to address these challenges and enhance the accuracy of spatiotemporal weather prediction. Drawing inspiration from the limitations of existing methodologies, we present an innovative approach that seamlessly integrates advanced token mixing and attention mechanisms. By leveraging both pooling and spatial mixing strategies, SFANet optimizes the processing of high-dimensional spatiotemporal sequences, preserving inter-component relational information and modeling extensive long-range relationships. To further enhance feature integration, we introduce a novel spatial-frequency attention module, enabling the model to capture intricate cross-modal correlations. Our extensive experimental evaluation on two distinct datasets, the Storm EVent ImageRy (SEVIR) and the Institute for Climate and Application Research (ICAR) - El Niño Southern Oscillation (ENSO) dataset, demonstrates the remarkable performance of SFANet. Notably, SFANet achieves substantial advancements over state-of-the-art methods, showcasing its proficiency in forecasting precipitation patterns and predicting El Niño events.

cs.CV↗

arXiv2024

An Innovative Networks in Federated Learning

This paper presents the development and application of Wavelet Kolmogorov-Arnold Networks (Wav-KAN) in federated learning. We implemented Wav-KAN \cite{wav-kan} in the clients. Indeed, we have considered both continuous wavelet transform (CWT) and also discrete wavelet transform (DWT) to enable multiresolution capabaility which helps in heteregeneous data distribution across clients. Extensive experiments were conducted on different datasets, demonstrating Wav-KAN's superior performance in terms of interpretability, computational speed, training and test accuracy. Our federated learning algorithm integrates wavelet-based activation functions, parameterized by weight, scale, and translation, to enhance local and global model performance. Results show significant improvements in computational efficiency, robustness, and accuracy, highlighting the effectiveness of wavelet selection in scalable neural network design.

eess.SP↗

arXiv2024

Wav-KAN: Wavelet Kolmogorov-Arnold Networks

In this paper, we introduce Wav-KAN, an innovative neural network architecture that leverages the Wavelet Kolmogorov-Arnold Networks (Wav-KAN) framework to enhance interpretability and performance. Traditional multilayer perceptrons (MLPs) and even recent advancements like Spl-KAN face challenges related to interpretability, training speed, robustness, computational efficiency, and performance. Wav-KAN addresses these limitations by incorporating wavelet functions into the Kolmogorov-Arnold network structure, enabling the network to capture both high-frequency and low-frequency components of the input data efficiently. Wavelet-based approximations employ orthogonal or semi-orthogonal basis and maintain a balance between accurately representing the underlying data structure and avoiding overfitting to the noise. While continuous wavelet transform (CWT) has a lot of potentials, we also employed discrete wavelet transform (DWT) for multiresolution analysis, which obviated the need for recalculation of the previous steps in finding the details. Analogous to how water conforms to the shape of its container, Wav-KAN adapts to the data structure, resulting in enhanced accuracy, faster training speeds, and increased robustness compared to Spl-KAN and MLPs. Our results highlight the potential of Wav-KAN as a powerful tool for developing interpretable and high-performance neural networks, with applications spanning various fields. This work sets the stage for further exploration and implementation of Wav-KAN in frameworks such as PyTorch and TensorFlow, aiming to make wavelets in KAN as widespread as activation functions like ReLU and sigmoid in universal approximation theory (UAT). The codes to replicate the simulations are available at https://github.com/zavareh1/Wav-KAN.

cs.LG↗

arXiv2024

Cost-efficient Knowledge-based Question Answering with Large Language Models

Knowledge-based question answering (KBQA) is widely used in many scenarios that necessitate domain knowledge. Large language models (LLMs) bring opportunities to KBQA, while their costs are significantly higher and absence of domain-specific knowledge during pre-training. We are motivated to combine LLMs and prior small models on knowledge graphs (KGMs) for both inferential accuracy and cost saving. However, it remains challenging since accuracy and cost are not readily combined in the optimization as two distinct metrics. It is also laborious for model selection since different models excel in diverse knowledge. To this end, we propose Coke, a novel cost-efficient strategy for KBQA with LLMs, modeled as a tailored multi-armed bandit problem to minimize calls to LLMs within limited budgets. We first formulate the accuracy expectation with a cluster-level Thompson Sampling for either KGMs or LLMs. A context-aware policy is optimized to further distinguish the expert model subject to the question semantics. The overall decision is bounded by the cost regret according to historical expenditure on failures. Extensive experiments showcase the superior performance of Coke, which moves the Pareto frontier with up to 20.89% saving of GPT-4 fees while achieving a 2.74% higher accuracy on the benchmark datasets.

cs.CL↗

arXiv2024

PandaLM: An Automatic Evaluation Benchmark for LLM Instruction Tuning Optimization

Instruction tuning large language models (LLMs) remains a challenging task, owing to the complexity of hyperparameter selection and the difficulty involved in evaluating the tuned models. To determine the optimal hyperparameters, an automatic, robust, and reliable evaluation benchmark is essential. However, establishing such a benchmark is not a trivial task due to the challenges associated with evaluation accuracy and privacy protection. In response to these challenges, we introduce a judge large language model, named PandaLM, which is trained to distinguish the superior model given several LLMs. PandaLM's focus extends beyond just the objective correctness of responses, which is the main focus of traditional evaluation datasets. It addresses vital subjective factors such as relative conciseness, clarity, adherence to instructions, comprehensiveness, and formality. To ensure the reliability of PandaLM, we collect a diverse human-annotated test dataset, where all contexts are generated by humans and labels are aligned with human preferences. Our results indicate that PandaLM-7B achieves 93.75% of GPT-3.5's evaluation ability and 88.28% of GPT-4's in terms of F1-score on our test dataset. PandaLM enables the evaluation of LLM to be fairer but with less cost, evidenced by significant improvements achieved by models tuned through PandaLM compared to their counterparts trained with default Alpaca's hyperparameters. In addition, PandaLM does not depend on API-based evaluations, thus avoiding potential data leakage. All resources of PandaLM are released at https://github.com/WeOpenML/PandaLM.

cs.CL↗

arXiv2024

DiffCalib: Reformulating Monocular Camera Calibration as Diffusion-Based Dense Incident Map Generation

Monocular camera calibration is a key precondition for numerous 3D vision applications. Despite considerable advancements, existing methods often hinge on specific assumptions and struggle to generalize across varied real-world scenarios, and the performance is limited by insufficient training data. Recently, diffusion models trained on expansive datasets have been confirmed to maintain the capability to generate diverse, high-quality images. This success suggests a strong potential of the models to effectively understand varied visual information. In this work, we leverage the comprehensive visual knowledge embedded in pre-trained diffusion models to enable more robust and accurate monocular camera intrinsic estimation. Specifically, we reformulate the problem of estimating the four degrees of freedom (4-DoF) of camera intrinsic parameters as a dense incident map generation task. The map details the angle of incidence for each pixel in the RGB image, and its format aligns well with the paradigm of diffusion models. The camera intrinsic then can be derived from the incident map with a simple non-learning RANSAC algorithm during inference. Moreover, to further enhance the performance, we jointly estimate a depth map to provide extra geometric information for the incident map estimation. Extensive experiments on multiple testing datasets demonstrate that our model achieves state-of-the-art performance, gaining up to a 40% reduction in prediction errors. Besides, the experiments also show that the precise camera intrinsic and depth maps estimated by our pipeline can greatly benefit practical applications such as 3D reconstruction from a single in-the-wild image.

cs.CV↗